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Ethyl 2-(2-isobutyl-6-quinolyloxy-8-p-toluenesulfonamido)acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ETHYL 2-(2-ISOBUTYL-6-QUINOLYLOXY-8-P-TOLUENESULFONAMIDO)ACETATE. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 316124-91-1. Molecular formula: C24H28N2O5S. Mole weight: 456.55. Purity: 0.96. IUPACName: ethyl 2-[8-[(4-methylphenyl)sulfonylamino]-2-(2-methylpropyl)quinolin-6-yl]oxyacetate. Canonical SMILES: CCOC(=O)COC1=CC(=C2C(=C1)C=CC(=N2)CC(C)C)NS(=O)(=O)C3=CC=C(C=C3)C. Product ID: ACM316124911. Alfa Chemistry ISO 9001:2015 Certified.
Isobutyl Acetoacetate
Isobutyl Acetoacetate. Group: Biochemicals. Alternative Names: Acetoacetic Acid Isobutyl Ester. Grades: Highly Purified. CAS No. 7779-75-1. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
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Isobutyl phenoxyacetate
Isobutyl phenoxyacetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: isobutyl phenoxyacetate;2-Phenoxyacetic acid isobutyl ester;2-methylpropyl 2-(phenoxy)acetate;2-methylpropyl 2-(phenoxy)ethanoate. Product Category: Heterocyclic Organic Compound. CAS No. 5432-66-6. Molecular formula: C12H16O3. Mole weight: 208.25364. Product ID: ACM5432666. Alfa Chemistry ISO 9001:2015 Certified.
2-Methylpropyl2-[[methyl(2-methylpropoxy)phosphoryl]sulfanylmethylsulfanyl]acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID53121, LS-12348, ACETIC ACID, 2-(MERCAPTOMETHYLTHIO)-, ISOBUTYL ESTER, S-ESTER with O-ISOBUTYL ME, 74789-30-3, Acetic acid, 2-(mercaptomethylthio)-, isobutyl ester, S-ester with O-isobutyl methylphosphonothioate. Product Category: Heterocyclic Organic Compound. CAS No. 74789-30-3. Molecular formula: C12H25O4PS2. Mole weight: 328.428 g/mol. Purity: 0.96. IUPACName: 2-methylpropyl 2-[[methyl(2-methylpropoxy)phosphoryl]sulfanylmethylsulfanyl]acetate. Canonical SMILES: CC(C)COC(=O)CSCSP(=O)(C)OCC(C)C. Density: 1.135g/cm³. Product ID: ACM74789303. Alfa Chemistry ISO 9001:2015 Certified.
Alarelin acetate
Alarelin acetate is a synthetic Gonadotrophin-releasing hormone agonist. It is the acetate form of a hypothalamic peptide. It is a potent LH-RH agonist in rats and mice. It reversibly delays sexual maturation in rats, stimulates spawning activity in fish. It could inducte ovulation and is used to treat endmometriosis. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Uses: Alarelin acetate could inducte ovulation and is used to treat endmometriosis. it is responsible for the secretion of gonadotropins, luteinizing hormone (lh) and follicle-stimulating hormone (fsh), from the pituitary glands. Synonyms: LHRH-A; 6-D-Ala-10-D-gly-LHRH-ethylamide; Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; 6-D-Ala-10-D-gly-LHRH-ethylamide; (S)-1-((3S,6S,9S,12S,15R,18S,21S)-3-((1H-imidazol-5-yl)methyl)-6-((1H-indol-3-yl)methyl)-21-(3-((diaminomethylene)amino)propyl)-12-(4-hydroxybenzyl)-9-(hydroxymethyl)-18-isobutyl-15-methyl-1,4,7,10,13,16,19-heptaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,17,20-heptaazadocosan-22-oyl)-N-ethylpyrrolidine-2-carboxamide diacetate. Grades: >98%. CAS No. 79561-22-1. Molecular formula: C60H86N16O16. Mole weight: 1287.42.
Goserelin Acteate
N-(21-((1H-indol-3-yl)methyl)-1,1-diamino-12-(tert-butoxymethyl)-6-(2-(2-carbamoylhydrazinecarbonyl)cyclopentanecarbonyl)-15-(4-hydroxybenzyl)-18-(hydroxymethyl)-25-(1H-imidazol-5-yl)-9-isobutyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacos-1-en-24-yl)-5-oxopyrrolidine-2-carboxamide Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2. injectable gonadotropin releasing hormone superagonist (GnRH agonist) or luteinizing hormone antiproliferative activity in breast, prostate and endometrial cancers. CAS No. 145781-92-6. Product ID: 1-01628. Molecular formula: C59H84N18O14. Mole weight: 1269.42. Purity: 0.99. Properties: water soluble. Categories: Goserelin acetate.
Ibufenac Ethyl Ester
Ibufenac Ethyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Acetic acid, (p-isobutylphenyl)-, ethyl ester (7CI,8CI),4-(2-Methylpropyl)benzeneacetic acid ethyl ester, Ethyl p-isobutylphenylacetate, Ethyl (4-isobutylphenyl)acetate. CAS No. 15649-02-2. IUPAC Name: ethyl 2-[4-(2-methylpropyl)phenyl]acetate. Molecular formula: C14H20O2. Mole weight: 220.31. Catalog: APS15649022. SMILES: CCOC(=O)Cc1ccc(CC(C)C)cc1. Format: Neat. Shipping: Room Temperature.
Ibufenac Methyl Ester
Ibufenac Methyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Methyl (4-isobutylphenyl)acetate, 2-(4-Isobutylphenyl)acetic acid methyl ester,4-(2-Methylpropyl)benzeneacetic acid methyl ester. CAS No. 61566-33-4. IUPAC Name: methyl 2-[4-(2-methylpropyl)phenyl]acetate. Molecular formula: C13H18O2. Mole weight: 206.28. Catalog: APS61566334. SMILES: COC(=O)Cc1ccc(CC(C)C)cc1. Format: Neat. Shipping: Room Temperature.
2-(N-Isobutyl-3,5-Dimethylisoxazole-4-Sulfonamido)Acetic Acid. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
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4'-Isobutylacetophenone
A degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen impuritiy. Group: Biochemicals. Alternative Names: 1-[4- (2-Methylpropyl) phenyl]ethanone; 1-Acetyl-4-isobutylbenzene; 1-[4-(2-Methylpropyl)phenyl]-1-ethanone; 1-[4- (2-Methylpropyl) phenyl]ethanone; 4- (2-Methylpropyl) acetophenone; NSC 173015; p-Acetylisobutylbenzene; p-Isobutylacetophenone; p-Isobutylphenyl Methyl Ketone; 4-IBAP. Grades: Highly Purified. CAS No. 38861-78-8. Pack Sizes: 1g. US Biological Life Sciences.
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(4-Isobutyl-piperazin-1-yl)-oxo-acetic acid
(4-Isobutyl-piperazin-1-yl)-oxo-acetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (4-ISOBUTYL-PIPERAZIN-1-YL)-OXO-ACETIC ACID;AKOS BB-3862. Product Category: Heterocyclic Organic Compound. CAS No. 713522-59-9. Molecular formula: C10H18N2O3. Mole weight: 214.26. Purity: >98. IUPACName: 2-[4-(2-methylpropyl)piperazin-1-yl]-2-oxoacetic acid. Canonical SMILES: CC(C)CN1CCN(CC1)C(=O)C(=O)O. Density: 1.155g/cm³. Product ID: ACM713522599. Alfa Chemistry ISO 9001:2015 Certified.
9-Desmethyl-alpha-Dihydro-Tetrabenazine
9-Desmethyl-alpha-Dihydro-Tetrabenazine is one of Tetrabenazine derivatives. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: (+)-9-O-Desmethyl-a-dihydrotetrabenazine; 1H-Naphtho[2,3-c]pyran-3-aceticacid,3,4,5,10-tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-,(1R,3S); Desoxyfrenolicin; (2R,3R,11bR)-9-O-desmethyldihydrotetrabenazine; (+)-deoxyfrenolicin; 1H-Naphtho(2,3-c)pyran-3-acetic acid,3,4,5,10-tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-,(1R-trans); 9-o-Desmethyl-alpha-dihydrotetrabenazine; 3-isobutyl-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2,9-diol. Grades: ≥95%. CAS No. 1065193-59-0. Molecular formula: C18H27NO3. Mole weight: 305.41.
Ac-LEHD-AFC
Ac-LEHD-AFC is a fluorogenic substrate for caspase-4, 5 and 9. Synonyms: N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine; N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin; Caspase-9 substrate; L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; (4S,7S,10S,13S)-10-((1H-imidazol-5-yl)methyl)-7-(2-carboxyethyl)-4-isobutyl-2,5,8,11-tetraoxo-13-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12-tetraazapentadecan-15-oic acid. Grades: ≥95%. CAS No. 210345-03-2. Molecular formula: C33H38F3N7O11. Mole weight: 765.69.
Alamethicin (Antibiotic U-22324)
Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. Alamethicin contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules. Group: Biochemicals. Alternative Names: (3S,12R)-1-((S)-1-((6S,12S,15S,21S,30S)-1-((R)-1-(2-Acetamido-2- methylpropanoyl) pyrrolidin-2-yl) -15- (3-amino-3-oxopropyl) -30-isobutyl-21-isopropyl- 3, 3, 6, 9, 9, 2, 18, 18, 24, 24, 33, 33-dodecamethyl-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31- undecaoxo-2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32-undecaazatetratri acontan-34- oyl)pyrrolidin-2-yl)-12-(((R)-5-amino-1-(((S)-1-hydroxy-3-phenylpropan-2-yl)amino)-1, 5-dioxopentan-2-yl)carbamoyl)-3-isopropyl-6,6,9,9-tetramethyl-1,4,7,10-tetraoxo-2,5, 8,11-tetraazapentadecan-15-oic Acid; Antibiotic U-22324. Grades: Purified. CAS No. 27061-78-5. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H???N??O??, Molecular Weight: 1964.31. US Biological Life Sciences.
Alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: alpha-[2-(Diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide;Pentisomide. Product Category: Heterocyclic Organic Compound. Appearance: White Crystalline Solid. CAS No. 78833-03-1. Molecular formula: C19H33N3O. Mole weight: 319.48482. Purity: 0.96. IUPACName: 2-[2-[di(propan-2-yl)amino]ethyl]-4-methyl-2-pyridin-2-ylpentanamide. Canonical SMILES: CC(C)CC(CCN(C(C)C)C(C)C)(C1=CC=CC=N1)C(=O)N. ECNumber: 278-989-5. Product ID: ACM78833031. Alfa Chemistry ISO 9001:2015 Certified.
A cell-permeable 4-hydroxy-2-oxo quinoline carboxamide that acts as an agonist of AMPK signaling. It is shown to reduce fat storage in C. elegans (EC50 ~0.1uM) and reduce the expression level of fat-7 (a C. elegans ortholog of mammalian stearoyl-CoA desaturase-1), through aak-1 (an ortholog for the AMPK-a1 catalytic subunit) and K08F8.2 (a transcription factor) dependent mechanisms. In addition, it markedly reduces the number of lipid droplets in HepG2 human hepatocarcinoma cells at 25uM, and elicits the phosphorylation and inactivation of acetyl coenzyme A carboxylase (ACC, the enzyme that catalyzes the rate-limiting step in de novo fatty acid synthesis). F17-induced ACC phosphorylation can be abrogated by simultaneous treatment with an AMPK inhibitor compound C. Group: Biochemicals. Grades: Highly Purified. CAS No. 280112-24-5. Pack Sizes: 5mg. US Biological Life Sciences.
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Des-Acety-Cetrorelix
Des-Acety-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Alanine amide; Cetrorelix Impurity-9; Des-Ac-Cetrorelix; 3-(2-Naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; (S)-N-((R)-1-amino-1-oxopropan-2-yl)-1-((2S,5S,8R,11S,14S,17R,20R,23R)-23-amino-20-(4-chlorobenzyl)-2-(3-((diaminomethylene)amino)propyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-24-(naphthalen-2-yl)-4,7,10,13,16,19,22-heptaoxo-17-(pyridin-3-ylmethyl)-8-(3-ureidopropyl)-3,6,9,12,15,18,21-heptaazatetracosanoyl)pyrrolidine-2-carboxamide; D-Alaninamide, 3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-. CAS No. 121081-09-2. Molecular formula: C68H90ClN17O13. Mole weight: 1389.02.
Ibufenac is an analog of ibuprofen, and also acts as a COX inhibitor. Ibufenac can be used as an analgesic and anti-inflammatory agent but exhibits hepatotoxicity. Synonyms: Dytransin; Ibunac; 4-Isobutylphenylacetic acid; 2-[4-(2-methylpropyl)phenyl]acetic acid; NSC 99976. Grades: ≥95%. CAS No. 1553-60-2. Molecular formula: C12H16O2. Mole weight: 192.3.
L-Ala(10)-Cetrorelix
L-Ala(10)-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-Ala-NH2; (S)-N-((S)-1-amino-1-oxopropan-2-yl)-1-((2S,5S,8R,11S,14S,17R,20R,23R)-20-(4-chlorobenzyl)-2-(3-((diaminomethylene)amino)propyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-23-(naphthalen-2-ylmethyl)-4,7,10,13,16,19,22,25-octaoxo-17-(pyridin-3-ylmethyl)-8-(3-ureidopropyl)-3,6,9,12,15,18,21,24-octaazahexacosanoyl)pyrrolidine-2-carboxamide; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-L-alaninamide. CAS No. 2886712-13-4. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06.
N-Cyanoacetyl-N'-isobutylurea
N-Cyanoacetyl-N'-isobutylurea. Group: Biochemicals. Alternative Names: 2-Cyano-N- [ [ (2-methylpropyl) amino] carbonyl] acetamide. Grades: Highly Purified. CAS No. 59341-75-2. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C8H13N3O2. US Biological Life Sciences.
Worldwide
N-Cyanoacetyl-N'-isobutylurea
N-Cyanoacetyl-N'-isobutylurea. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Cyano-N-[[(2-methylpropyl)amino]carbonyl]acetamide. Product Category: Heterocyclic Organic Compound. Appearance: White Crystals. CAS No. 59341-75-2. Molecular formula: C8H13N3O2. Mole weight: 183.21. Purity: 0.96. IUPACName: 2-cyano-N-(2-methylpropylcarbamoyl)acetamide. Canonical SMILES: CC(C)CNC(=O)NC(=O)CC#N. Product ID: ACM59341752. Alfa Chemistry ISO 9001:2015 Certified.
NNGH
NNGH is a cell-permeable inhibitor of matrix metalloproteinases (MMPs). It has been used to study the role of MMP-3 (stromelysin 1) in biological systems. Synonyms: N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid; ??Matrix Metalloproteinase-3 Inhibitor II; MMP-3 Inhibitor II; N-hydroxy-2-[(4-methoxyphenyl)sulfonyl-(2-methylpropyl)amino]acetamide. Grades: ≥99%. CAS No. 161314-17-6. Molecular formula: C13H20N2O5S. Mole weight: 316.4.
Rifalazil
Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase. Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml. Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia?infection, Clostridium difficile?associated diarrhea (CDAD), and tuberculosis (TB). Uses: Designed for use in research and industrial production. Additional or Alternative Names: RIFALAZIL;KRM 1648;3-Hydroxy-5-(4-isobutylpiperazinyl)benzoxazinorifamycin;5,12-Dihydroxy-2,4-dimethyl-10-[4-(2-methyl-propyl)-l-piperazinyl]-2,7-[oxy(5-acetoxy-7,9-dihydroxy-3-methoxy-4,6,8,10,14-pentamethyl-15-oxo-l,ll,13-pentadecatriene-l,15-diyl)imino]-6H-benzofuro[4,5-a]phenoxazine-l(2H),6-dione;1-Deoxy-1-dehydro-1-oxo-3-hydroxy-5-[4-(2-methylpropyl)piperazino]rifamycin VIII. Product Category: Inhibitors. Appearance: Solid. CAS No. 129791-92-0. Molecular formula: C51H64N4O13. Mole weight: 941.07. Purity: 0.9806. Canonical SMILES: CC(C)CN(CC1)CCN1C2=CC(O3)=C(C(O)=C2)N=C(C3=C(NC(/C(C)=C\C=C\[C@@H]([C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@@H]([C@@H]([C@H](/C=C/O[C@@]4(C)O5)OC)C)OC(C)=O)C)=O)C6=O)C7=C6C(O)=C(C)C5=C7C4=O. Product ID: ACM129791920. Alfa Chemistry ISO 9001:201
TAK-448
TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Synonyms: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. Grades: 98%. CAS No. 1234319-68-6. Molecular formula: C58H80N16O14. Mole weight: 1225.36.
TAK-683
TAK-683 is an investigational peptide derivative of metastin under the development of Millennium. It is a KISS1R protein agonist. Phase I development for prostate cancer was discontinued. Uses: Prostate cancer. Synonyms: TAK-683, TAK 683, TAK683; (S)-2-((R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)-N1-((8S,11S,17S,20S,21R)-8-(((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)succinamide. Grades: 98%. CAS No. 872719-49-8. Molecular formula: C64H83N17O13. Mole weight: 1298.47.
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