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| Product | Description | |
|---|---|---|
| Isobutyramide | 100g Pack Size. Group: Building Blocks, Organics. Formula: (CH3)2CHCONH2. CAS No. 563-83-7. Prepack ID 32947370-100g. Molecular Weight 87.12. See USA prepack pricing. |  |
| Isobutyramide | 25g Pack Size. Group: Building Blocks, Organics. Formula: (CH3)2CHCONH2. CAS No. 563-83-7. Prepack ID 32947370-25g. Molecular Weight 87.12. See USA prepack pricing. | |
| Isobutyramide | Isobutyramide. CAS No. 563-83-7. |  Pennsylvania PA |
| Isobutyramide | Isobutyramide. Group: Biochemicals. Grades: Highly Purified. CAS No. 563-83-7. Pack Sizes: 50g, 100g, 250g. US Biological Life Sciences. |  Worldwide |
| LIM Kinase Inhibitor I, LIMKi 3 (N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide) | A cell-permeable pyrazolylthiazolo-isobutyramide compound that acts as a potent LIM kinase inhibitor (IC50 = 7 and 8nM against LIMK1 and LIMK2, respectively) and effectively suppresses cellular cofilin phosphorylation (IC50 ~1uM in A549 and MDA-MB-231 cultures) without affecting tubulin polymerization or inducing cytotoxicity (EC50 >10uM in A549 proliferation & colony formation assays). Shown to effectively destabilize F-actin structure in MDA-MB-231 breast cancer cells (3 to 10uM) with concomitant blockage of invasion (by 93% at 10uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1338247-35-0. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?F?N?OS. US Biological Life Sciences. | Worldwide |
| N-(9-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-6-oxo-5,9-dihydro-6H-purin-2-yl)isobutyramide | N-(9-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-6-oxo-5,9-dihydro-6H-purin-2-yl)isobutyramide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O,4'-C-methylene-N-(2-methyl-1-oxopropyl)-. Product Category: Nucleosides. CAS No. 206055-72-3. Molecular formula: C36H37N5O8. Mole weight: 667.72. Purity: 0.95. IUPACName: N-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-5H-purin-2-ylidene]-2-methylpropanamide. Product ID: PR206055723. Alfa Chemistry ISO 9001:2015 Certified. |  |
| N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-ethynyl-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide | N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-ethynyl-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Uses: Designed for use in research and industrial production. Product Category: Nucleosides. Molecular formula: C37H36FN5O7. Mole weight: 681.72. Purity: >97%. Product ID: PR01189. Alfa Chemistry ISO 9001:2015 Certified. | |
| N-Naphthalen-2-yl-isobutyramide | N-Naphthalen-2-yl-isobutyramide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-NAPHTHALEN-2-YL-ISOBUTYRAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 71182-40-6. Molecular formula: C14H15NO. Mole weight: 213.275. Product ID: ACM71182406. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-Amino-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-N2-isobutyryl-2'-O-methyladenosine | 2-Amino-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-N2-isobutyryl-2'-O-methyladenosine, a compound hailed within the biomedical industry, exhibiting intriguing medicinal potential. It serves as a catalyst in the creation of tailored therapeutics, meticulously designed to thwart precise pathways by selectively maneuvering functions. Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methyl-2-[(2-methyl-1-oxopropyl)amino]-; N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-6-(((dimethylamino)methylene)amino)-9H-purin-2-yl)isobutyramide; 2'-OMe-5'-DMT-2,6-diamino purine riboside (n6,n6-dmf) (n2-ibu); 2'-OMe-5'-DMT-N2-amino-ibu rA(N6-DMF). Grade: ≥97%. CAS No. 869354-79-0. Molecular formula: C39H45N7O7. Mole weight: 723.84. |  |
| 2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine | 2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine, a remarkable and influential compound, is extensively utilized in the realm of biomedical research. Its widespread application lies in investigating the impeding effect it manifests on viral RNA synthesis across diverse viral infections. This nucleoside analog showcases auspicious efficacy against select DNA and RNA viruses, thereby rendering it an invaluable asset in the arena of antiviral drug development and investigations pertaining to virology. Synonyms: 2'-Deoxy-N2-isobutyryl-2'-fluoroguanosine; N2-Isobutyryl-2'-fluoro-deoxyguanosine; 2'-Deoxy-2'-fluoro-N2-isobutyryl-D-guanosine; 2'-Fluoro-N2-isobutyryl-2'-deoxyguanosine; N-(9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 2'-F-dG(iBu). Grade: ≥97% by HPLC. CAS No. 80681-25-0. Molecular formula: C14H18FN5O5. Mole weight: 355.33. | |
| 2-Methyl-2-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]-propanamide | 2-Methyl-2-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]-propanamide. Synonyms: 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)isobutyramide; 2-Methyl-2-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]propanamide; (2R,3R,4S,5R,6S)-2-(Acetoxymethyl)-6-((1-amino-2-methyl-1-oxopropan-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate. Grade: ≥98%. CAS No. 207512-69-4. Molecular formula: C18H27NO11. Mole weight: 433.41. | |
| 2-Methylpropanamide-[d6] | 2-Methylpropanamide-[d6]. Uses: A useful deuterated synthetic intermediate. Synonyms: 2-Methyl-d3-propionic-3,3,3-d3-amide; 2-(Methyl-d3)-propanamide-3,3,3-d3; Isobutyramide-d6; 2-Methylpropanamide-d6; 2-Methylpropionamide-d6; Isobutyrimidic acid-d6; dimethylacetoamide-d6. Grade: ≥95%. CAS No. 1020719-64-5. Molecular formula: C4H3D6NO. Mole weight: 93.16. | |
| 2'-O-Methyl-N2-isobutyroylguanosine | 2'-O-Methyl-N2-isobutyroylguanosine is a biomedicine used in the reserch of certain diseases, including cancer. It acting as an antineoplastic compound and exhibiting potent activity against specific tumor cells. Its mechanism of action involves inhibiting cell growth and inducing apoptosis. Synonyms: N2-Isobutyryl-2'-O-methylguanosine; N2-Isobutyryl-2'-O-methyl-D-guanosine; IBU-2'-OME-G; N2-isobutyryl-O2'-methyl-guanosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 2'-O-methyl-N-(2-methyl-1-oxopropyl)-; 2'-O-Methyl-N-(2-methyl-1-oxopropyl)guanosine. Grade: ≥95%. CAS No. 63264-29-9. Molecular formula: C15H21N5O6. Mole weight: 367.36. | |
| 3'-O-TBDMS-2'-O-Me-rG(iBu) | Guanosine, 3'-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-2'-O-methyl-N-(2-methyl-1-oxopropyl)? - the nucleoside analog believed to hold great potential in the fight against a wide range of viral infections and certain cancers. Extensively researched for its ability to disrupt viral or cancerous DNA replication, Guanosine, 3'-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-2'-O-methyl-N-(2-methyl-1-oxopropyl)? has been shown to be effective against HCV, HIV, herpes simplex virus, leukemia and lung cancer - making it a powerful tool in the battle against these debilitating diseases. Synonyms: 3'-O-[(1,1-Dimethylethyl)dimethylsilyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)guanosine; Guanosine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-; N-(9-((2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)isobutyramide. Grade: ≥98% by HPLC. CAS No. 863097-97-6. Molecular formula: C21H35N5O6Si. Mole weight: 481.62. | |
| 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine | 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine is a revolutionary biomedical substance renowned for its remarkable antiviral and antiproliferative attributes. Synonyms: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-guanosine; N2-iBu-DMT-2'-O-4'-C-Locked-Gr; N-(9-{(1R,3R,4R,7S)-1-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-7-hydroxy-2,5-dioxa-bicyclo[2.2.1]hept-3-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O,4'-C-methylene-N-(2-methyl-1-oxopropyl)-; (1R,3R,4R,7S)-1-(4,4'-Dimethoxytrityloxymethyl)-7-hydroxy-3-(2-N-isobutyrylguanin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane. Grade: ≥95%. CAS No. 206055-72-3. Molecular formula: C36H37N5O8. Mole weight: 667.71. | |
| 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine | 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine, an indispensable compound utilized in the biomedical sector, showcases immense promise in combatting a plethora of diseases and disorders, namely cancer and viral infections. Its extraordinary configuration empowers it to disrupt replication procedures, rendering it a highly efficacious agent against antiviral and anticancer fronts. Synonyms: N2-iBu-2'-O-TBDMS-5'-O-DMT-G; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine; N2-iBu-DMT-2'-O-TBDMS-Gr; N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanosine; 5'-DMT-2'-tBDSilyl Guanosine (n-ibu). Grade: ≥95%. CAS No. 81279-39-2. Molecular formula: C41H51N5O8Si. Mole weight: 769.96. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine | 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine, an intriguing bioactive compound, has garnered attention in the biomedical industry for its potential antiviral prowess. Demonstrating commendable efficacy in impeding viral replication, it holds promise in combatting viral ailments such as herpes and hepatitis. However, the precise workings of this compound remain enigmatic, warranting further exploration in the realm of antiviral drug development. Synonyms: N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 2'-O-MOE-5'-O-DMT-G(iBu); 5'-O-DMT-2'-O-MOE-N2-iBu-rG; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine. Grade: ≥95%. CAS No. 251647-50-4. Molecular formula: C38H43N5O9. Mole weight: 713.78. | |
| 5'-O-TBDMS-N2-isobutyryl-2'-deoxyguanosine | 5'-O-TBDMS-N2-isobutyryl-2'-deoxyguanosine, a nucleoside analog, is an intricate and multifaceted tool, crucial in the synthesis of antisense oligonucleotides, employed for the treatment of a variety of devastating ailments like viral infections and cancer. Alongside this, it is a significant addition to the biomedical arsenal as it helps researchers study gene expression. Its myriad of uses and intricate nature is indispensable in contemporary scientific research. Synonyms: 5'-O-TBDMS-N2-ibu-dG; N2-isobutyryl-5'-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine; N-(9-((2R,4S,5R)-5-(((tert-Butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; N-Isobutyryl-5'-O-tert-butyldiMethylsilyl-2'-deoxyguanosine; N2-iBu-5'-O-TBS-dG; Guanosine, 2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-; 2'-Deoxy-5'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine. Grade: ≥97% by HPLC. CAS No. 85326-10-9. Molecular formula: C20H33N5O5Si. Mole weight: 451.60. | |
| 5'-Trt-N2-ibu-rG | 5'-Trt-N2-ibu-rG, a nucleoside analog, exhibits strong potential as an effective anticancer agent, as it has been demonstrated to impede the growth and spread of certain cancer cell types, including leukemia and breast cancer. The mechanism behind its tumor suppression lies in its specific targeting of the RNA polymerase II enzyme, a key factor in the transcription of cancer-promoting genes, thus providing a promising avenue for chemotherapy. Synonyms: 5'-O-Trt-N2-ibu-rG; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grade: ≥98% by HPLC. Molecular formula: C33H32N5O6. Mole weight: 595.65. | |
| 8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine | 8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine is an antiviral compound, holding immense potential in the development of antiviral therapeutics. Synonyms: N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-8-phenylmethoxy-1H-purin-2-yl]-2-methylpropanamide; 8-BENZYLOXY-N2-ISOBUTYRYL-2/'-DEOXYGUANOSINE; 8-(Benzyloxy)-2'-deoxy-N-(2-methylpropanoyl)guanosine; N-(8-(benzyloxy)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grade: ≥ 90%. CAS No. 136859-75-1. Molecular formula: C21H25N5O6. Mole weight: 443.46. | |
| 8-Oxo-N2-isobutyryl-2'-deoxyguanosine | 8-Oxo-N2-isobutyryl-2'-deoxyguanosine is an exceptional biomedical compound, rendered as a discerning indicator for DNA impairment. It assumes an integral role as a substrate for DNA reparation. Its utilization propels extensive investigation into oxidative species-induced DNA lesions, thereby furnishing profound elucidation into an array of afflictions spanning cancer to neurodegenerative disorders. Synonyms: 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE; 8-HYDROXY-N2-ISOBUTRYL-2/'-DEOXYGUANOSINE; N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,8-dioxo-1,7-dihydropurin-2-yl]-2-methylpropanamide; DTXSID40721580; MFCD22373349; N2-Isobutyryl-8-oxo-2'-deoxyguanosine; 2'-Deoxy-N-(2-methylpropanoyl)-8-oxo-7,8-dihydroguanosine; N-(8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grade: ≥ 90%. CAS No. 136859-76-2. Molecular formula: C14H19N5O6. Mole weight: 353.33. | |
| BMS-5 | BMS-5, a LIMK inhibitor, has been found to restrain the cofilin phosphorylation in MDA-MB-231 breast cancer cells. Synonyms: LIMKi 3; N-(5-(1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide; N-{5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-1,3-thiazol-2-yl}-2-methylpropanamide; BMS 5; BMS5. Grade: 98%. CAS No. 1338247-35-0. Molecular formula: C17H14Cl2F2N4OS. Mole weight: 431.29. | |
| Cytidine,2'-deoxy-N-(2-methyl-1-oxopropyl)-(9ci) | Cytidine,2'-deoxy-N-(2-methyl-1-oxopropyl)-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ST056931, 110522-75-3, N-(1-((2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-2-OXO-1,2-DIHYDROPYRIMIDIN-4-YL)ISOBUTYRAMIDE, ACMC-20efww, Cytidine,2-deoxy-N-(2-methyl-1-oxopropyl)- (9CI), AC1N7Y3L, I6261_SIGMA, N4-Isobutyryl-2-deoxycytidine, MCULE-3684872135, N4-Isobutyryl-2 inverted exclamation marka-deoxycytidine, N-[1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]-2-methylpropanamide, N-{1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxohydropyrimidin-4-yl}-2-meth ylpropanamide. Product Category: Heterocyclic Organic Compound. CAS No. 110522-75-3. Molecular formula: C13H19N3O5. Mole weight: 297.31. Purity: 0.95. IUPACName: N-[1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]-2-methylpropanamide. Canonical SMILES: CC(C)C(=O)NC1=NC(=O)N(C=C1)C2CC(C(O2)CO)O. Density: 1.49g/cm³. Product ID: ACM110522753. Alfa Chemistry ISO 9001:2015 Certified. | |
| Flutamide EP Impurity F | Flutamide EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-nitro-5-(trifluoromethyl)phenyl)isobutyramide. CAS No. 151262-93-0. Molecular formula: C11H11F3N2O3. Mole weight: 276.21. Catalog: APB151262930. |  |
| Isobutanamidoxime | Isobutanamidoxime was shown to exhibit antitumor activities and were active against P388 leukemia. Group: Biochemicals. Alternative Names: Isobutyramide Oxime; Isobutyramidoxime; Isopropylcarboxamide Oxime; N-Hydroxy-2-methylpropanimidamide; N-hydroxyisobutyramidin e; N'-hydroxyisobutyramidin e. Grades: Highly Purified. CAS No. 35613-84-4. Pack Sizes: 1g. Molecular Formula: C4H10N2O, Molecular Weight: 102.14. US Biological Life Sciences. | Worldwide |
| N-(3-Amino-4-chlorophenyl)-2-methylpropanamide | N-(3-Amino-4-chlorophenyl)-2-methylpropanamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(3-AMINO-4-CHLOROPHENYL)-2-METHYLPROPANAMIDE, 916813-19-9, Ambcb4030051, AGN-PC-015UOR, SureCN5050812, CTK5H0330, MolPort-004-295-183, ZINC08732387, AKOS000101478, AG-H-76570, MCULE-2107450157, N-(3-Amino-4-chlorophenyl)isobutyramide, AK121251. Product Category: Heterocyclic Organic Compound. CAS No. 916813-19-9. Molecular formula: C10H13ClN2O. Mole weight: 212.676020 [g/mol]. Purity: 0.96. IUPACName: N-(3-amino-4-chlorophenyl)-2-methylpropanamide. Canonical SMILES: CC(C)C(=O)NC1=CC(=C(C=C1)Cl)N. Density: 1.25g/cm³. Product ID: ACM916813199. Alfa Chemistry ISO 9001:2015 Certified. | |
| N-Desmethyl Netupitant-[d6] | N-Desmethyl Netupitant-[d6] is the labelled analogue of N-Desmethyl Netupitant, which is a derivative of Netupitant. Netupitant is a selective neurokinin 1 receptor antagonist with potential antiemetic activity. Synonyms: N-Desmethyl Netupitant D6; N,α,α-Trimethyl-N-[4-(2-methylphenyl)-6-(1-piperazinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-benzeneacetamide-d6; 2-[3,5-Bis(trifluoromethyl)phenyl]-N-methyl-N-[6-(piperazin-1-yl)-4-o-tolylpyridin-3-yl]isobutyramide-d6. Grade: >98%. CAS No. 2070015-21-1. Molecular formula: C29H24D6F6N4O. Mole weight: 570.60. | |
| (S)-9-[3-(4,4'-Dimethoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine | (S)-9-[3-(4,4'-Dimethoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine, a chemical employed in the realm of biomedicine, is of prime utility for combating viral infections by thwarting viral replication. Herpes simplex and varicella-zoster, among other viruses, fall under its ambit. As a reference standard, it is widely deployed to scrutinize the antiviral potential of nucleoside analogs. Synonyms: Propanamide, N-[9-[(2S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-2-hydroxypropyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl-; N-(9-{(S)-3-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-hydroxy-propyl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide. Grade: ≥95%. CAS No. 182625-67-8. Molecular formula: C33H35N5O6. Mole weight: 597.66. | |
| 2,2'-Azobis[2-methyl-propanimidamide Dihydrochloride | 2,2'-Azobis[2-methyl-propanimidamide Dihydrochloride. Group: Biochemicals. Alternative Names: 2,2'-(1,2-Diazenediyl)bis[2-methylpropanimidamide Dihydrochloride; 2,2'-Azobis[2-methyl-propionamidine Dihydrochloride; 2,2-Azobis(2-amidinopropane) Dihydrochloride; 2,2'-Azobis(2-amidinopropane) Dihydrochloride; 2,2'-Azobis(2-methylpropionamidine) Dihydrochloride; 2,2'-Azobis(isobutyramidine hydrochloride); 2, 2'-Azobis (isobutyramidine) Dihydrochloride; 2,2'-Azobis(propane-2-carboxamidine) Dihydrochloride; 2,2'-Azobisamidinopropane dihydrochloride; 2, 2'-Azobisisobutyramidiniu m Chloride; AAPH; AIBA; Azobis (isobutyramidine) Dihydrochloride; Azobisisobutyramidiniu m Dichloride; Azostarter V 50; MS 1; MS 1 (catalyst); NC 32P; V 50; VA 50; VA 50 (catalyst); Vazo 56; Vazo 56WSP; Vazo 56WSW; Wako V 50. Grades: Highly Purified. CAS No. 2997-92-4. Pack Sizes: 5g. Molecular Formula: C8H20Cl2N6, Molecular Weight: 271.19. US Biological Life Sciences. | Worldwide |
| 2',3'-ddG(N-iBu) CE Phosphoramidite | 2',3'-ddG(N-iBu) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxyguanosine (ddG) with an N-isobutyryl protecting group. This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddG(N-iBu) Phosphoramidite; N2-Isobutyryl-2',3'-dideoxyguanosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-Dideoxyguanosine (N-iBu) 5'-phosphoramidite; 2',3'-ddG(iBu) CE Phosphoramidite; 2-Cyanoethyl (((2S,5R)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. Grade: ≥97%. Molecular formula: C23H36N7O5P. Mole weight: 521.56. | |
| 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite | 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite, a critical chemical reagent in the biomedicine industry, demonstrates immense value for the synthesis of nucleosides and nucleotides. Its pivotal role lies within the realm of research and development of pharmaceuticals, particularly anti-cancer and antiviral drugs. CAS No. 2376756-54-4. Molecular formula: C43H52FN8O6P. Mole weight: 826.9. | |
| 2-cyanoethyl (((2S,3R,4R,5R)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite | 2-cyanoethyl (((2S,3R,4R,5R)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite exhibits paramount significance within the biomedical industry. It serves as a vital ingredient in oligonucleotide synthesis for multifarious applications encompassing gene expression analysis, antisense technology, and the pioneering sector of drug development. CAS No. 2376756-55-5. Molecular formula: C44H55N8O7P. Mole weight: 838.93. | |
| 2-Isobutyramido guanosine 2,3,5-tris(isobutanoate) | 2-Isobutyramido guanosine 2, 3, 5-tris(isobutanoate) is a fascinating biomedical compound that possesses immense potential in studying a diverse array of ailments such as cancer and neurodegenerative disorders. Its exceptional ability to proficiently target and modulate specific cellular signaling pathways lends it considerable promise as a pioneering research. Synonyms: 2-Isobutyramido guanosine 2,3,5-tris(2-methylpropanoate); Guanosine, N-(2-methyl-1-oxopropyl)-, 2',3',5'-tris(2-methylpropanoate). CAS No. 70337-80-3. Molecular formula: C26H37N5O9. Mole weight: 563.60. | |
| 2'-OMe G(iBu) PACE amidite | 2'-OMe G(iBu) PACE amidite is a reagent used in oligonucleotide synthesis. It contains a methyl (Me) group at the 2' position of ribose, guanosine (G) potentially protected with an isobutyl (iBu) group, and incorporates a modification referred to as 'PACE'. This modification introduces specific functionalities or properties to the oligonucleotide. The exact nature of 'PACE' would determine its role in the synthesis process and the characteristics of the resulting oligonucleotide. Synonyms: 2'-OMe G(iBu) PACE amidite; 5'-Dimethoxytrityl-N-isobutyryl-2'-OMe-Guanosine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; 1-Cyano-2-methylpropan-2-yl 2-((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(diisopropylamino)phosphaneyl)acetate. Grade: >98%. CAS No. 1355047-26-5. Molecular formula: C49H62N7O10P. Mole weight: 940.05. | |
| ((2R,3S,5R)-3-((tert-Butyldimethylsilyl)oxy)-5-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) ((2R,3S,5R)-5-(4-((E)-((dimethylamino)methylene)amino)-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl) phosphate | Targeting HIV and hepatitis B, this nucleotide analogue presents itself as the key to inhibiting viral DNA polymerase, effectively stopping the replications of viruses. With its versatile properties, it also serves as a potent treatment for certain cancer types. Synonyms: ((2R,3S,5R)-3-((tert-butyldimethylsilyl)oxy)-5-(2-isobutyrylamino-6-oxo-1H-purine-9(6H)-Yl)tetrahydrofuran-2-yl)methyl(2-cyanoethyl)((2R,3S,5R)-5-(4-((E)-((dimethylamino)methylene)amino)-2-oxo-1,3,5-triazine-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl)phosphate. Molecular formula: C34H52N11O11PSi. Mole weight: 849.90. | |
| 3-(Isobutyramido)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylic acid | 3-(Isobutyramido)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206969-41-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C11H12N4O3, Molecular Weight: 248.238. US Biological Life Sciences. | Worldwide |
| 5-amino-3-((4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | 5-amino-3-((4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one is an imperative pharmaceutical compound, exhibiting remarkable applications in research of diverse ailments encompassing viral infections and cancer. Synonyms: (R)-2-(((R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxypropan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl benzoate. CAS No. 1229414-16-7. Molecular formula: C9H12N6O4. Mole weight: 268.23. | |
| 5'-O-DMT-3'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 2'-CE phosphoramidite | 5'-O-DMT-3'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 2'-CE phosphoramidite is a specialized phosphoramidite used for the synthesis of oligonucleotides. It includes a 5'-dimethoxytrityl (DMT) group for 5'-hydroxyl protection, a 3'-tert-butyldimethylsilyl (TBDMS) group for 3'-hydroxyl protection, and an N2-isobutyryl group to protect the exocyclic amine of the guanine base. Additionally, it has a cyanoethyl (CE) group at the 2'-position of the phosphoramidite. These protective groups help facilitate efficient synthesis and stability of the oligonucleotides, making this compound valuable for research, diagnostic, and therapeutic applications. Synonyms: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 2'-CE phosphoramidite; (2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-TBDMS-ibu-rG Phosphoramidite; 3'-O-TBDMS-5'-O-DMT-N2-iBu-rG CED phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-guanosine-3'-cyanoethyl Phosphoramidite. Grade: ≥95%. CAS No. 1445905-51-0. Molecular formula: C50H68N7O9PSi. Mole weight: 970.18. | |
| 8-oxo-dG-CE Phosphoramidite | 8-oxo-dG-CE Phosphoramidite is an indispensable compound assuming a pivotal role in oligonucleotide research and development. Its contributes to the exploration of therapeutic drugs aimed at DNA repair and ailments associated with oxidative stress. Synonyms: 5'-Dimethoxytrityl-N2-isobutyryl-8-oxo-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-OXO-dG(ibu) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6,8-dioxo-1,6,7,8-tetrahydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DNA 8-oxo-G(iBu) amidite. Grade: 95%. CAS No. 143060-53-1. Molecular formula: C44H54N7O9P. Mole weight: 855.93. | |
| Corynecin III | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Methamphenicol; dimethylamphenicol; N-[(1R,2R)-1-(Hydroxymethyl)-2-hydroxy-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; d-threo-2-Isobutyramido-1-(p-nitrophenyl)-1,3-propanediol; N-[β-Hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-2-methyl-D-threo-propionamide. Grade: >99% by HPLC. CAS No. 18048-95-8. Molecular formula: C13H18N2O5. Mole weight: 282.29. | |
| dG(iBu)-3'-PS Phosphoramidite | dG(iBu)-3'-PS Phosphoramidite is a deoxyguanosine-derived phosphoramidite designed for oligonucleotide synthesis incorporating a 3'-phosphorothioate (PS) linkage. The 3'-PS modification replaces a non-bridging oxygen atom in the phosphate group with a sulfur atom, providing enhanced nuclease resistance and improved biological stability for the resulting oligonucleotides. The guanine base is protected with an isobutyryl (iBu) group at the N2 position to prevent side reactions during synthesis while maintaining proper base-pairing properties. This phosphoramidite is widely used in therapeutic applications, such as antisense oligonucleotides and siRNA, where increased enzymatic resistance, stability, and prolonged activity are essential for performance. Synonyms: 5'-DMT-dG(iBu)-3'-PS-Phosphoramidite; dG(iBu) ThioPhosphamidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; S-(2-(((((2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate. Grade: ≥90%. CAS No. 178272-31-6. Molecular formula: C48H53N6O8PS2. Mole weight: 937.08. | |
| Faldaprevir | Faldaprevir, also known as BI-201335, is a potent NS3/NS4A protease inhibitor potentially for the treatment of HCV infection. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Faldaprevir; BI-201335; BI 201335; BI201335. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 801283-95-4. Molecular formula: C40H49BrN6O9S. Mole weight: 869.83. Purity: >98%. IUPACName: (1R,2S)-1-((2S,4R)-4-((8-bromo-2-(2-isobutyramidothiazol-4-yl)-7-methoxyquinolin-4-yl)oxy)-1-((S)-2-(((cyclopentyloxy)carbonyl)amino)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-2-vinylcyclopropane-1-carboxylic acid. Canonical SMILES: O=C([C@]1(NC([C@H]2N(C([C@@H](NC(OC3CCCC3)=O)C(C)(C)C)=O)C[C@H](OC4=CC(C5=CSC(NC(C(C)C)=O)=N5)=NC6=C(Br)C(OC)=CC=C46)C2)=O)[C@H](C=C)C1)O. Product ID: ACM801283954. Alfa Chemistry ISO 9001:2015 Certified. | |
| Guanosine, 3'-?deoxy-?2'-?O-?(1,?1-?difluoro-?2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl), 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a chemical utilized in RNA synthesis. It serves as a modified nucleoside to improve the binding affinity of RNA with therapeutic drugs in treating viral diseases such as HIV and hepatitis C. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-99-3. Molecular formula: C46H57F2N8O8P. Mole weight: 918.96. | |
| Guanosine, 3'-?deoxy-?2'-?O-?(2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an indispensable compound employed extensively in the realm of biomedical exploration, specifically in nucleic acid synthesis. This remarkable compound acts as a modulated foundational unit in the paradigm of solid-phase DNA synthesis, consequently enabling the assimilation of aforementioned guanosine variant into the very fabric of DNA filaments. By virtue of its distinctive phosphoramidite structure, this exemplary specimen facilitates focused inquiry into precise DNA modifications. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-14-9. Molecular formula: C46H59N8O8P. Mole weight: 882.98. | |
| Guanosine, 3'-?deoxy-?2'-?O-?ethyl-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-2'-O-ethyl-3'-[[(4-methoxyphenyl)?diphenylmethyl]?amino]?-N-(2-methyl-1-oxopropyl)?-, 5'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite] is a pivotal constituent, emanates as a linchpin in the explicit domain of nucleic acid synthesis, intently within DNA and RNA exploration. It confers enhanced prospects for manufacturing modified nucleotides as well as derivatives pertaining to nucleic acids, necessitated for investigations encompassing the structural, functional and behavioral attributes pertinent to DNA and RNA molecules, rendering significant insights. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-ethoxy-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 2299279-11-9. Molecular formula: C45H57N8O7P. Mole weight: 852.96. | |
| Guanosine, 3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?methyl-?1-?oxopropyl)?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Guanosine, 3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] serves as an indispensable compound within the biomedical sector, utilized for the synthesis of modified nucleotides. Its paramount importance lies in its significant contribution to the advancement of nucleic acid-based therapeutics, including antisense oligonucleotides, siRNAs and aptamers. Synonyms: ((2S,3R,4R,5R)-4-(allyloxy)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299283-17-1. Molecular formula: C46H57N8O7P. Mole weight: 864.97. | |
| HMTase Inhibitor IX, MM-102 (Histone Methyltransferase Inhibitor IX, MM102, (S) -N- (bis (4-Fluoro phenyl ) methy l )-1- (2- (2-ethyl -2-isobutyramidobutanamid o)-5-guanidinopentanamido) cyclopentane carboxami de , TFA) | A cell-permeable peptidomimetic that prevents MLL1 (Mixed Lineage Leukemia 1) from complex assembling with WDR5 (Trp-Asp Repeat Domain 5), RbBP5 (Retinoblastoma Binding Protein 5), and ASH2L (Absent Small or Homeotic-2-Like) for enhanced H3K4 methyltransferase activity (IC50 = 0.4nM). Shown to reduce HoxA9 and Meis-1 mRNA expression in myeloblasts derived from MLL1-AF9-transduced murine bone marrow cells (50uM for 96 h) and preferentially inhibit the growth of MLL1-AF4-harboring MV4;11 and MLL1-ENL-harboring KOPN8 leukemia cultures (GI50 in 7 days = 25uM) via apoptosis induction, while exhibiting much reduced potency against BCR-ABL-dependent K562 cells (GI50 in 7 days = 84uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O? · CF?CO?H. US Biological Life Sciences. | Worldwide |
| iBu-G-(S)-GNA phosphoramidite | Bz-G-(S)-GNA phosphoramidite: A Potent Anticancer and Antiviral Reagent for DNA Synthesis and Modification. This widely employed derivative is recognized for its high-purity and stability, enabling the synthesis of oligonucleotides with amplified efficacy and selectivity. Renowned for its use in drug discovery and development, the Bz-G-(S)-GNA nucleoside intermediate supports treatment of devastating conditions like HIV and cancer. Synonyms: 2'-O-(2-Cyanoethoxy)(diisopropylamino)phosphino-3'-O-(4,4'-dimethoxytriphenyl)methyl-N2-isobutyryl-(S)-9-(2,3-dihydroxypropyl)guanine; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]methyl]ethyl 2-cyanoethyl ester; (S)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite; (S)-GNA-G(iBu) phosphoramidite; DMT-G(iBu)-(S)-GNA Phosphoramidite. Grade: ≥98%. CAS No. 182625-68-9. Molecular formula: C44H52N7O7P. Mole weight: 797.88. | |
| O6-Diphenylcarbamoyl-N2-isobutyrylguanine | O6-Diphenylcarbamoyl-N2-isobutyrylguanine. Group: Biochemicals. Alternative Names: 2-Isobutyramido-9H-purin-6-yl diphenylcarbamate; Diphenyl-carbamic acid (2-isobutyryl guanine) ester. Grades: Highly Purified. CAS No. 185610-53-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C22H20N6O3. US Biological Life Sciences. | Worldwide |
| (R)-2-(((S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxypropan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl benzoate | (R)-2-(((S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxypropan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl benzoate. Uses: Designed for use in research and industrial production. Product Category: Nucleosides. CAS No. 1120329-60-3. Molecular formula: C42H43N5O9. Mole weight: 761.83. Purity: 0.95. Product ID: PR1120329603. Alfa Chemistry ISO 9001:2015 Certified. | |
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