Isoenzyme Suppliers USA
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Product | Description | |
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Creatine kinasa MM isoenzyme (CC-MM) Quick inquiry Where to buy Suppliers range | Creatine kinasa MM isoenzyme (CC-MM). Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS007109. Format: Matrix Material. Shipping: Dry ice. | |
Lactate dehydrogenase isoenzyme 1 (LD1) Quick inquiry Where to buy Suppliers range | Lactate dehydrogenase isoenzyme 1 (LD1). Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS009293. Format: Matrix Material. Shipping: Dry ice. | |
Lactate Dehydrogenase Isoenzyme 1 (LD1) (catalytic activity concentration) Quick inquiry Where to buy Suppliers range | Lactate Dehydrogenase Isoenzyme 1 (LD1) (catalytic activity concentration). Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Catalog: APS009294. Shipping: Dry ice. | |
1,2,3,4-Tetrahydro Staurosporine Quick inquiry Where to buy Suppliers range | Staurosporine derivative for use as isoenzyme PKCα inhibitors and anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 220038-19-7. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
(17 β ) -N-[2, 5-Bis (trifluoromethyl) phenyl]-3-oxo-4-azaandrost-5-ene-17-carboxamide Quick inquiry Where to buy Suppliers range | (17 β ) -N-[2, 5-Bis (trifluoromethyl) phenyl]-3-oxo-4-azaandrost-5-ene-17-carboxamide is an intermediate in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Group: Biochemicals. Grades: Highly Purified. CAS No. 164656-21-7. Pack Sizes: 25mg, 100mg. Molecular Formula: C27H30F6N2O2. US Biological Life Sciences. | Worldwide |
(17 β ) -N-[2, 5-Bis (trifluoromethyl) phenyl]-3-oxo-androst-4-ene-17-carboxamide Quick inquiry Where to buy Suppliers range | (17 β ) -N-[2, 5-Bis (trifluoromethyl) phenyl]-3-oxo-androst-4-ene-17-carboxamide is an intermediate in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Group: Biochemicals. Grades: Highly Purified. CAS No. 164656-19-3. Pack Sizes: 50mg, 250mg. Molecular Formula: C28H31F6NO2. US Biological Life Sciences. | Worldwide |
2-Bromoacetophenone Quick inquiry Where to buy Suppliers range | 2-Bromoacetophenone is a brominated acteophenone derivative. 2-Bromoacetophenone has been shown to completely and irreversibly inactivate human liver aldehyde dehydrogenase (EC 1.2.1.3) isoenzymes E1 and E2. 2-Bromoacetophenone and its derivatives display some inhibitory activity on neutral protein tyrosine.inhibitors. Group: Biochemicals. Alternative Names: 1-Bromo-2-phenylethan-2-one; 1-Phenyl-2-bromoethanone; 2-Bromo-1-phenylethan-1-one; 2-Bromo-1-phenylethanone; 2-Bromoacetophenone; Benzoylmethyl Bromide; Bromoacetophenone; Bromomethyl Phenyl Ketone; NSC 9807; Phenacyl Bromide; Phenyl Bromomethyl Ketone; Stauffer 4644; α-Bromoacetophenone; β-Bromoacetophenone; ω-Bromacetophenone; ω-Bromoacetophenone. Grades: Highly Purified. CAS No. 70-11-1. Pack Sizes: 50g. US Biological Life Sciences. | Worldwide |
2-Iodo-3-Oxo-4-aza-5α-androst-17 β-carboxylic Acid Quick inquiry Where to buy Suppliers range | 2-Iodo-3-Oxo-4-aza-5α-androst-17 β-carboxylic Acid is a reactant in the synthesis of Duasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia. Group: Biochemicals. Grades: Highly Purified. CAS No. 140700-63-6. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H28INO3, Molecular Weight: 445.33. US Biological Life Sciences. | Worldwide |
2-Ketobutyric Acid Quick inquiry Where to buy Suppliers range | A substrate for the determination of lactate dehydrogenase isoenzymes.This compound is suitable for lactate dehydrogenase (LDH) related research. Group: Biochemicals. Alternative Names: 2-Oxobutanoic Acid; 2-Oxobutyric Acid; 2-Ketobutanoic Acid; 2-Ketobutyric Acid; 2-Oxo-n-butyric Acid; 2-Oxobutanoic Acid; 2-Oxobutyric Acid; 3-Methylpyruvic Acid; NSC 60533; Propionylformic Acid; α-Ketobutyric Acid; α-Oxo-n-butyric Acid; α-Oxobutanoic Acid; α-Oxobutyric Acid; α-keto-n-Butyric Acid. Grades: Reagent Grade. CAS No. 600-18-0. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
3-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy]-1,2-propanediol. (Mixture of Diastereomers) Quick inquiry Where to buy Suppliers range | 3-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy]-1,2-propanediol is involved in biological studies as microsomal cytochrome P 450 isoenzymes from Penicillium italicum interaction with sterol demethylation inhibitor fungicides. Group: Biochemicals. Grades: Highly Purified. CAS No. 86491-83-0. Pack Sizes: 50mg, 500mg. Molecular Formula: C14H16Cl2N2O3. US Biological Life Sciences. | Worldwide |
4-Diethylaminobenzaldehyde Quick inquiry Where to buy Suppliers range | DEAB is a potent inhibitor of cytosolic (class 1) aldehyde dehydrogenase (ALDH) enzymes (IC50 values 0.057 μM, 1.2 μM, 3.0 μM, 1.2 μM, 0.16 μM, and 13 μM for inhibition of ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1, ALDH2, and ALDH5A1, respectively). DEAB is also an excellent substrate for ALDH3A1, and an irreversible inhibitor of ALDH7A1 (KI value 100 μM). Uses: 4-(diethylamino)benzaldehyde is a mechanism-based inhibitor for human aldehyde dehydrogenase isoenzymes. potent and reversible inhibitor of mouse and human class i aldehyde dehydrogenase. Synonyms: 4-(diethylamino)benzaldehyde. Grades: 99 %. CAS No. 120-21-8. Molecular formula: C11H15NO. Mole weight: 177.24. | |
4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside-6-sulfate sodium salt Quick inquiry Where to buy Suppliers range | It is a fluorescent substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (Hexosaminidase A). Synonyms: 4-Methylumbelliferyl N-acetyl-b-D-glucosaminide-6-sulfate sodium salt; 4-Methylumbelliferyl 2-acetamido-2-deoxy-6-sulphate-b-D-glucopyranoside sodium salt; 4MU-b-D-galactoside-6-sulphate sodium salt; 4-Methylumbelliferyl-b-D-galactoside-6-sulphate sodium salt; 7-[[2-(Acetylamino)-2-deoxy-6-O-sulfo-β-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one Monosodium Salt. Grades: ≥95%. CAS No. 142439-99-4. Molecular formula: C18H20NNaO11S. Mole weight: 481.41. | |
4-Methylumbelliferyl 2-Acetamido-2-deoxy-b-D-glucopyranoside 6-Sulphate Sodium Salt Quick inquiry Where to buy Suppliers range | 4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside 6-sulphate sodium salt is a fluorescent substrate for isoenzyme A of N-acetyl- β-D-glucosaminidase (Hexosaminidase A). It can also be used in biological study of characterization of the mutant β-subunit of β-hexosaminidase for dimer formation responsible for the adult form of Sandhoff disease with the motor neuron disease phenotype. Group: Biochemicals. Grades: Highly Purified. CAS No. 142439-99-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C18H21NO11S; Na, Molecular Weight: 459.422299. US Biological Life Sciences. | Worldwide |
4-Oxocyclohexane-1-Carbonitrile Quick inquiry Where to buy Suppliers range | 4-Oxocyclohexane-1-Carbonitrile (CAS# 34916-10-4) is used to prepare nicotinamides as PDE4 D isoenzymes inhibitors. It is also used as an anthranilic acid replacement in niacin receptor agonist. Synonyms: 4-oxocyclohexanecarbonitrile; 4-Oxo-cyclohexanecarbonitrile. CAS No. 34916-10-4. Molecular formula: C7H9NO. Mole weight: 123.15. | |
4SC-202 Quick inquiry Where to buy Suppliers range | 4SC-202 is a selective and potent, orallly available inhibitor of histone deacetylases (HDAC) specific for class 1 HDAC isoenzymes, with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. 4SC-202 also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). In addition, 4SC-202 shows a broad anti-proliferative activity towards human cancer cell lines with a mean IC50 of 0.7 μM. Synonyms: 4SC202; 4SC-202; 4SC 202; domatinostat; (E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide. CAS No. 910462-43-0. Molecular formula: C23H21N5O3S. Mole weight: 447.51. | |
4SC-202 Tosylate Quick inquiry Where to buy Suppliers range | 4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an accumulation of highly acetylated histones.This may inhibit tumor cell proliferation in susceptible tumor cells. HDACs, upregulated in many tumor types, are a class of enzymes that deacetylate chromatin histone proteins. Synonyms: 4SC-202; 4SC 202; 4SC202. Grades: 0.98. CAS No. 1186222-89-8. Molecular formula: C30H29N5O6S2. Mole weight: 619.711. | |
A 438079 hydrochloride Quick inquiry Where to buy Suppliers range | A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. It protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, but not by inflammasome activation. It partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores. Synonyms: 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride;A-438079 HCl;A-438079 hydrochloride; A438079 hydrochloride; A 438079 hydrochloride. Grades: >98 %. CAS No. 899507-36-9. Molecular formula: C13H10Cl3N5. Mole weight: 342.61. | |
CDP 840 hydrochloride Quick inquiry Where to buy Suppliers range | CDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase 4 (PDE4) (IC50 = 12 nM). It competitively inhibits all PDE4 isoenzymes. Synonyms: CDP840; CDP-840; CDP 840; CDP840 HCl; CDP840HCl. 4-[(2R)-2-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-phenylethyl]-pyridine hydrochloride. Grades: ≥98% by HPLC. CAS No. 162542-90-7. Molecular formula: C25H27NO2.HCl. Mole weight: 409.95. | |
Chidamide Quick inquiry Where to buy Suppliers range | Chidamide, also known as CS055 and HBI-8000, is an orally bioavailable benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10, with potential antineoplastic activity. Chidamide selectively binds to and inhibits HDAC leading to an increase of acetylation levels of histone protein H3. This agent also inhibits the expression of signaling kinases in the PI3K/Akt and MAPK/Ras signaling pathways and may result in cell cycle arrest and the induction of tumor cell apoptosis. This may inhibit tumor cell proliferation in susceptible tumor cells. HDACs, a class of enzymes that deacetylate chromatin histone proteins, are upregulated in many tumor types and play key roles in gene expression. Compared to some other benzamide type HDAC inhibitors, chidamide is more stable, more resistant to degradation and has a longer half-life. Synonyms: CS055; CS-055; CS 055; HBI-8000; HBI 8000; HBI8000; N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide. CAS No. 743420-02-2. Molecular formula: C22H19FN4O2. Mole weight: 390.418. | |
CRT0066854 Quick inquiry Where to buy Suppliers range | CRT0066854 is a selective and ATP-competitive inhibitor of the atypical PKC isoenzymes (IC50 values 639 nM and 132 nM for full-length PKCζ, PKCΙ, respectively). CRT0066854 decreases colony formation in HeLa cells, inhibits LLGL2 phosphorylation and polarized epithelial morphogenesis, and impedes directed migration of NRK cells. Synonyms: CRT0066854; CRT 0066854; CRT-0066854; (2S)-3-Phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine. Grades: 99%. CAS No. 1438881-19-6. Molecular formula: C24H25N5S. Mole weight: 415.55. | |
D-Homoarginine Hemisulfate Quick inquiry Where to buy Suppliers range | D-Homoarginine Hemisulfate is an enantiomer of L-Homoarginine, which is an inhibitor of alkaline phosphatase isoenzymes. Synonyms: N6-(Aminoiminomethyl)-D-lysine Hemisulfate Salt; (R)-2-Amino-6-guanidinohexanoic Acid Hemisulfate Salt. CAS No. 32733-73-6. Molecular formula: C14H34N8O8S. Mole weight: 474.54. | |
Diclofenamide Quick inquiry Where to buy Suppliers range | Diclofenamide is a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP). Group: Biochemicals. Alternative Names: 1,3-Disulfamoyl-4,5-dichlorobenzene; 1,3-Disulfamyl-4,5-dichlorobenzene; 3, 4-Dichloro-5-sulfamyl Benzene sulfonamide; 4,5-Dichloro-1,3-disulfamoylbenzene; 4,5-Dichloro-m-benzenedisulfonamide; Antidrasi; CB 8000; Daramide; Daranide; Dichlofenamide; Dichlorophenamide; Dichlorphenamide; Diclofenamid; Glaucol; Oratrol. Grades: Highly Purified. CAS No. 120-97-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
Dutasteride-13C6 Quick inquiry Where to buy Suppliers range | Labeled Dutasteride. Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride. Dutasteride is used in the treatment of benign prostatic hyperplasia. Group: Biochemicals. Alternative Names: (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N-[2, 5-Bis (trifluoromethyl) phenyl]-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetradecahydro-4a, 6a-dimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide-13C6; (5α,17 β)-. Grades: Highly Purified. CAS No. 1217685-27-2. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
L-Homoarginine-d4 Dihydrochloride Quick inquiry Where to buy Suppliers range | A labeled inhibitor of alkaline phosphatase isoenzymes. A labeled analog of Homoarginine. Group: Biochemicals. Alternative Names: N6-(Aminoiminomethyl)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
L-Homoarginine, Hydrochloride (2-Amino-6-guanidino-hexanoic Acid, HCl) Quick inquiry Where to buy Suppliers range | An inhibitor of alkaline phosphatase isoenzymes. Group: Biochemicals. Alternative Names: 2-Amino-6-guanidino-hexanoic Acid, HCl. Grades: Highly Purified. CAS No. 1483-01-8. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
L-Lactic dehydrogenase Quick inquiry Where to buy Suppliers range | L-Lactic dehydrogenase. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: IUB: 1.1.1.27;LACTIC DEHYDROGENASE;LACTIC DEHYDROGENASE BOVINE HEART;LACTIC ACID DEHYDROGENASE;LACTATE DEHYDROGENASE;LACTATE DEHYDROGENASE, HUMAN MUSCLE;LACTATE DEHYDROGENASE ISOENZYME-1, HUMAN;L-LACTATE DEHYDROGENASE. CAS No. 9001-60-9. Product ID: CDF4-0043. | |
Peroxidase Quick inquiry Where to buy Suppliers range | Peroxidase. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: Peroxidase froM horseradish(EIA Grade,Purified);84 kDa myeloperoxidase;89 kDa myeloperoxidase;ANTI-MYELOPEROXIDASE(N-TERMINAL) antibody produced in rabbit;Myeloperoxidase light chain;Apoperoxidase;Peroxidase isoenzymes Type XI: Apoenzyme from horseradish;ANTI-MYELOPEROXIDASE (CENTER) antibody produced in rabbit. CAS No. 9003-99-0. Product ID: CDF4-0034. | |
Piclamilast Quick inquiry Where to buy Suppliers range | Piclamilast is a potent and selective phosphodiesterase-4 (PDE4) inhibitor (IC50 = 1 nM at PDE4 from human neutrophils) with >19,000-fold selectivity over other PDE isoenzymes. Uses: Phosphodiesterase 4 inhibitors. Synonyms: Piclamilast; RP-73401; RP 73-401; RP 73401; RP 73 401; RP73401; RP 73401; 3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide; N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide. Grades: ≥99% by HPLC. CAS No. 144035-83-6. Molecular formula: C18H18Cl2N2O3. Mole weight: 381.25. | |
PKR-IN-1 Quick inquiry Where to buy Suppliers range | Activator of pyruvate kinase isoenzyme M2 (PKM2), an enzyme involved in glycolysis. Since all tumor cells exclusively express the embryonic M2 isoform of PK, it is hypothesized that PKM2 is a potential target for cancer therapy. Modulation of PKM2 might also be effective in the treatment of obesity, diabetes, autoimmune conditions, and antiproliferation-dependent diseases. Synonyms: PKR-IN-1; PKM2 activator 1020; PKM2 activator; Mitapivat. Grades: >98%. CAS No. 1260075-17-9. Molecular formula: C24H26N4O3S. Mole weight: 450.55. | |
Sterigmatocystin Quick inquiry Where to buy Suppliers range | Sterigmatocystin is a mycotoxin produced by several species of aspergillus. It is structurally related to the aflatoxins. It is mutagenic, teratogenic and carcinogenic and is less widespread and potent than Aflatoxin. It inhibits acyl-CoA. It is a cholesterol acyltransferase (ACAT) with selectivity for the ACAT2 isoenzyme. Synonyms: (3aR,12cS)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one; (3aR-cis)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one; NSC 201423; NSC 204985; Sterigmatocystine. Grades: >95% by HPLC. CAS No. 10048-13-2. Molecular formula: C18H12O6. Mole weight: 324.28. |