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An intermediate in the Ras farnesyltransferase inhibitor L-744832. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
An intermediate in the Ras farnesyltransferase inhibitor L-744832. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
L-744832 ((2S)-[(2S)-[(2R)-Amino-3-mercapto]-propylamino-(3S)-methyl]pentyloxy-3-phenylpropionyl-methionine SulfoneIsopropyl Ester Bis Hydrchloride)
Ras farnesyltransfer. Group: Biochemicals. Alternative Names: (2S)-[(2S)-[(2R)-Amino-3-mercapto]-propylamino-(3S)-methyl]pentyloxy-3-phenylpropionyl-methionine SulfoneIsopropyl Ester Bis Hydrchloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose is a vital compound used in the biomedical industry. It exhibits potential therapeutic applications in the treatment of various diseases. Actively investigated for its efficacy, this compound displays promising results in the treatment of inflammatory disorders, cancer, and certain viral infections. Its unique molecular structure and bioactive properties make it a valuable component in drug research and development within the biomedicine field. Synonyms: 1,2-O-Isopropylidene-6-methyl-sulfonyl-alpha-D-glucofuranose; 1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose; [(2R)-2-[(3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]-2-hydroxyethyl] methanesulfonate; (R)-2-Hydroxy-2-((3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethyl methanesulfonate; SCHEMBL7145842; (2R)-2-[(3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]-2-hydroxyethyl methanesulfonate. CAS No. 33557-25-4. Molecular formula: C10H18O8S. Mole weight: 298.31.
Used in the preparation of N-heterocyclic indole carboxamides as glycogen phosphorylase inhibitors. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-1,3-dioxolane-4-methanol 4-Methanesulfonate-d5; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl Methanesulfonate-d5; (±)-1,2-O-Isopropylidenepropane-1,2,3-triol 3-Mesylate-d5; DL-1-Methane sulfonylisopropyl idene glycerol-d5; Solketal Mesylate-d5. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
2,3-O-Isopropylidene-1,4-di-O-tosyl-D-threitol
2,3-O-Isopropylidene-1,4-di-O-tosyl-D-threitol, a highly versatile compound, holds significant importance in the field of biomedical research due to its diverse applications. Acting as a safeguarding agent, it proves essential in the synthesis of numerous drugs and pharmaceutical intermediates. Synonyms: (+)-1,4-Di-O-tosyl-2,3-O-isopropylidene-D-threitol; 1,4-Di-O-tosyl-2,3-O-isopropylidene-D-threitol; (4R-trans)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethyl bis(toluene-p-sulphonate); ((4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene) bis(4-methylbenzenesulfonate); (+)-2,3-O-Isopropylidene-1,4-di-O-tosyl-D-threitol; [(4R,5R)-2,2-dimethyl-5-[(4-methylphenyl)sulfonyloxymethyl]-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate; (4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol 4,5-Bis(4-methylbenzenesulfonate)1111. CAS No. 51064-65-4. Molecular formula: C21H26O8S2. Mole weight: 470.56.
2,3-O-Isopropylidene-1,4-di-O-tosyl-L-threitol
2,3-O-Isopropylidene-1,4-di-O-tosyl-L-threitol, a highly significant compound extensively utilized in the field of biomedicine, demonstrates exceptional prowess as a precursor for the synthesis of a plethora of therapeutic drugs and molecules. This indispensable substance effortlessly contributes to the development of cardiovascular medications, anti-inflammatory marvels, and potent antiviral remedies. Synonyms: (-)-1,4-di-O-Tosyl-2,3-O-isopropylidene-L-threitol; ((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene) bis(4-methylbenzenesulfonate); [(4S,5S)-2,2-dimethyl-5-[(4-methylphenyl)sulfonyloxymethyl]-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate; 1,4-di-o-tosyl-2,3-o-isopropylidene-l-threitol; MFCD00003212; (-)-1,4-Di-o-tosyl-2,3-o-isopropylidenethreitol; [(4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene) bis(4-methylbenzenesulfonate); C21H26O8S21111. CAS No. 37002-45-2. Molecular formula: C21H26O8S2. Mole weight: 470.56.
2,3-O-Isopropylidene-1,6-di-O-p-toluenesulfonyl-α-L-sorbofuranose, an essential component in the biomedical field, showcases immense possibilities in carbohydrate derivative synthesis and glycosylation reactions. As a result of its distinctive configuration, this compound illustrates immense promise in combating a wide range of ailments such as cancer, cardiovascular disorders, and infectious diseases. Synonyms: 2,3-O-Isopropylidene-1,6-di-O-p-toluenesulfonyl-a-L-sorbofuranose; alpha-L-Sorbofuranose, 2,3-O-(1-methylethylidene)-, 1,6-bis(4-methylbenzenesulfonate); 1,6-Di-O-tosyl-2,3-O-isopropylidene-alpha-L-sorbofuranose; 2,3-O-Isopropylidene-1,6-ditosyl-L-sorbose; [(3aS,5S,6R,6aS)-6-hydroxy-2,2-dimethyl-3a-[(4-methylphenyl)sulfonyloxymethyl]-6,6a-dihydro-5H-furo[2,3-d][1,3]dioxol-5-yl]methyl 4-methylbenzenesulfonate; DTXSID101132627; W-202039; 1,6-Di-O-tosyl-2,3-O-isopropylidene-?-L-sorbofuranose; 2,3-O-Isopropylidene-1,6-di-O-tosyl-alpha-L-sorbofuranose?. CAS No. 2484-55-1. Molecular formula: C23H28O10S2. Mole weight: 528.59.
2,3-O-Isopropylidene-b-D-ribofuranosylamine p-toluenesulphonate salt
2,3-O-Isopropylidene-b-D-ribofuranosylamine p-toluenesulphonate salt is a specialized reagent commonly used in the synthesis of nucleoside analogs, which are integral to a variety of antiviral and anticancer drugs. It promotes efficient bond formation between complex molecules. Synonyms: 2,3-O-Isopropylidene-beta-D-ribofuranosylamine p-toluenesulfonate salt; 2,3-O-Isopropylidene-ss-D-ribofuranosylamine, p-Toluenesulfonate Salt;2,3-O-Isopropylidene-b-D-ribofuranosylamine p-toluenesulphonate salt; ((3AR,4R,6R,6aR)-6-amino-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 4-methylbenzenesulfonate; [(3aR,4R,6R,6aR)-4-amino-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol; 4-methylbenzenesulfonic acid; 4-methylbenzene-1-sulfonic acid; [(3aR,4R,6R,6aR)-6-amino-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]methanol;((3AR,4R,6R,6aR)-6-amino-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol4-methylbenzenesulfonate. CAS No. 29836-10-0. Molecular formula: C8H15NO4.C7H8O3S. Mole weight: 361.41.
(-)-2,3-O-Isopropylidene-L-threitol-1,4-dimethane sulfonate stands as a cornerstone in the biomedical realm. It exerts its significance in the synthesis of an array of medicinal agents and pharmaceutics. Synonyms: [(4s,5s)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]dimethanediyl dimethanesulfonate; [(4S,5S)-2,2-dimethyl-5-(methylsulfonyloxymethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate; (-)-2,3-O-Isopropylidene-L-threitol-1,4-dimethane sulfonate; (-)-2,3-O-ISOPROPYLIDENE-L-THREITOL 1,4-DIMETHANE SULFONATE; NSC60499; 1,3-Dioxolane-4,5-dimethanol,2,2-dimethyl-, 4,5-dimethanesulfonate, (4S,5S)-1111. CAS No. 4248-74-2. Molecular formula: C9H18O8S2. Mole weight: 318.37.
3,4-Di-O-acetyl-1,2-O-isopropylidene-5-O-p-toluenesulfonyl-a-L-sorbopyranose acts as a key intermediate in the synthesis of several drugs targeting metabolic disorders, viral infections, and autoimmune diseases. Synonyms: 3,4-Di-O-acetyl-1,2-O-isopropylidene-5-O-p-toluenesulfonyl-a-L-sorbopyranose; 3,4-Di-O-acetyl-1,2-O-isopropylidene-5-O-tosyl-alpha-L-sorbose; [(5S,6S,7S,8S)-6-acetyloxy-2,2-dimethyl-8-(4-methylphenyl)sulfonyloxy-1,3,10-trioxaspiro[4.5]decan-7-yl] acetate; 3,4-DI-O-ACETYL-1,2-O-ISOPROPYLIDENE-5-O-TOSYL-alpha-L-SORBOPYRANSE;3,4-Di-O-acetyl-1,2-O-isopropylidene-5-O-tosyl-?-L-sorbose; 3,4-Di-O-acetyl-1,2-O-isopropylidene-5-O-tosyl-a-L-sorbose. CAS No. 53821-66-2. Molecular formula: C20H26O10S. Mole weight: 458.48.
MCC7840 is a sulfonylurea non-steroidal anti-inflammatory drug and a potent selective inhibitor of NLRP3 inflammasome with IC50 <100 nM. Synonyms: N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]-1-(propan-2-yl)-1H-pyrazole-3-sulfonamide; Inzomelid; 1H-Pyrazole-3-sulfonamide, N-(((1,2,3,5,6,7-hexahydro-S-indacen-4-yl)amino)carbonyl)-1-(1-methylethyl)-; N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide; MCC7840. CAS No. 1995067-59-8. Molecular formula: C19H24N4O3S. Mole weight: 388.48.
isopropyl (4- (2- (5-Methylpyrazine-2-carboxamido) ethyl) phenyl) sulfonylcarbamate. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS009126. Format: Neat. Shipping: Room Temperature.
isopropyl 4-methylbenzenesulfonate
Isopropyl 4-Methylbenzenesulfonate (CAS# 2307-69-9) is a sulfonic acid ester, a potentialy alkylating agent. Studies suggest Isopropyl p-Tosylate may exert genotoxic effects in bacterial and mammalian cell systems. Synonyms: Isopropyl p-Tosylate; 2-Propyl tosylate; 4-Methylbenzenesulfonic Acid 1-Methylethyl Ester. CAS No. 2307-69-9. Molecular formula: C10H14O3S. Mole weight: 214.28.
Isopropyl Benzenesulfonate
Isopropyl Benzenesulfonate is a sulfonate ester that acts as a potential genotoxic impurity in drug substances. It may exert genotoxic effects in bacterial and mammalian cell systems. Synonyms: Benzenesulfonic Acid Isopropyl Ester; Benzenesulfonic Acid 1-Methylethyl Ester; Isopropyl Besylate. Grades: > 95%. CAS No. 6214-18-2. Molecular formula: C9H12O3S. Mole weight: 200.26.
Isopropyl Benzenesulfonate
Sulfonate ester genotoxic impurity found in active pharmaceutical ingredients. It has potential to exert toxic effects in bacterial and mammalian cells. Group: Biochemicals. Alternative Names: Benzenesulfonic Acid Isopropyl Ester; Benzenesulfonic Acid 1-Methylethyl Ester; Isopropyl besylate. Grades: Highly Purified. CAS No. 6214-18-2. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences.
Methyl 2,3-O-isopropylidene-5-O-(4-toluenesulfonyl)-b-D-ribofuranoside is a chemical compound extensively employed in the biomedical sector, serving as a foundational reactant in a myriad of drug synthesis endeavors. It is used in the research of synthesis of nucleoside analogs or antiviral compounds. Synonyms: ((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl 4-methylbenzenesulfonate; FVP47IPF3Z; UNII-FVP47IPF3Z; Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside; methyl 2,3-o-isopropylidene-5-o-tosyl-beta-d-ribofuranoside; EC 609-920-2; NSC 85192; Methyl 2,3-O-(1-methylethylidene)-5-O-((4-methylphenyl)sulfonyl)-beta-D-ribofuranoside; Methyl 2,3-O-isopropylidene-5-O-p-toluenesulfonyl-beta-D-ribofuranoside; b-D-Ribofuranoside, methyl 2,3-O-(1-methylethylidene)-,4-methylbenzenesulfonate; methyl 2, 3-o- (1-methylethylidene) -5-o-[ (4-methylphenyl) sulfonyl]pentofuranoside; [(3aR,4R,6R,6aR)-4-methoxy-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl 4-methylbenzenesulfonate; 13007-50-6; [(3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]methyl 4-methylbenzene-1-sulfonate. CAS No. 13007-50-6. Molecular formula: C16H22O7S. Mole weight: 358.4.
Mps1-IN-1
Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor with IC50 of 367 nM; >1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk. Synonyms: Mps1-IN-1; 1125593-20-5; 1-(4-(4-(2-(Isopropylsulfonyl)phenylamino)-1H-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol; 1-[3-methoxy-4-[[4-(2-propan-2-ylsulfonylanilino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]piperidin-4-ol; 1MPS1-IN-1; 3gfw; 1-(4-((4-((2-(isopropylsulfonyl)phenyl)amino)-1H-pyrrolo[2,3-b]pyridin-6-yl)amino)-3-methoxyphenyl)piperidin-4-ol; MLS003230944; GTPL9271; SCHEMBL4051419; CHEMBL1235786; BDBM36485; CHEBI:91379; DTXSID60649015; AVB59320; BCP27688; AKOS027422816; CS-3776; NCGC00387463-01; NCGC00387463-04; HY-13298; MS-29898; SMR001913509; F85109; A925638; J-503190; Q27087728; 1-(3-methoxy-4-{[4-({2-[(1-methylethyl)sulfonyl]phenyl}amino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino}phenyl)piperidin-4-ol; 1-[3-Methoxy-4-({4-[2-(propane-2-sulfonyl)anilino]-1H-pyrrolo[2,3-b]pyridin-6-yl}amino)phenyl]piperidin-4-ol; s22. Grades: >98%. CAS No. 1125593-20-5. Molecular formula: C28H33N5O4S. Mole weight: 535.66.
An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 1-Propanesulfonamide, N-[4-(4-fluorophenyl)-5-formyl-6-(1-methylethyl)-2-pyrimidinyl]-2-hydroxy-N,2-dimethyl-; Rosuvastatin Impurity 37. Grades: >95%. CAS No. 2101546-09-0. Molecular formula: C19H24FN3O4S. Mole weight: 409.48.
PF-4217329
PF-04217329 is a potent and selective EP2 receptor agonist on intraocular pressure in preclinical models of glaucoma. It is a prodrug of CP-544326. It is well tolerated in preclinical species. Uses: Pf-04217329 is useful for intraocular pressure of glaucoma. Synonyms: PF-4217329, PF 4217329, PF4217329, PF-04217329, PF04217329, PF 04217329, Taprenepag isopropyl; Propan-2-yl 2- [3- [ [ (4-pyrazol-1-ylphenyl) methyl-pyridin-3-ylsulfonylamino] methyl] phenoxy] acetate; PF4217329; PF-04217329; PF04217329; Isopropyl 2-(3-((N-(4-(1H-pyrazol-1-yl)benzyl)pyridine-3-sulfonamido)methyl)phenoxy)acetate. Grades: >98 %. CAS No. 1005549-94-9. Molecular formula: C27H28N4O5S. Mole weight: 520.60.
Rosuvastatin (6S)-Lactone Impurity
An impurity of Rosuvastatin. Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: N-[(6S)-8-Fluoro-5,6-dihydro-4-(1-methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-methylmethane sulfonamide; N-((S)-8-fluoro-6-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)-4-isopropyl-5,6-dihydrobenzo[h]quinazolin-2-yl)-N-methylmethanesulfonamide. CAS No. 854898-47-8. Molecular formula: C22H26FN3O5S. Mole weight: 463.52.
Rosuvastatin EP Impurity A
Rosuvastatin EP Impurity A is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Synonyms: (3R,5S,6E)-7-[2-(2,N-Dimethyl-2-hydroxypropane-1-sulfonamido)-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl](methyl)amino]-6-(1-methylethyl)-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,E)-7-(4-(4-Fluorophenyl)-2-((2-hydroxy-N,2-dimethylpropyl)sulfonamido)-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid; S-Desmethyl-S-(2-hydroxy-2-methylpropyl) Rosuvastatin; 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-, (3R,5S,6E)-; (3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid; Rosuvastatin Calcium EP Impurity A. Grades: ≥95%. CAS No. 1715120-13-0. Molecular formula: C25H34FN3O7S. Mole weight: 539.62.