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Isoproterenol Sulfate Dihydrate. Uses: Designed for use in research and industrial production. Appearance: Solid. CAS No. 299-95-6. Molecular formula: C22H34N2O6·H2SO4·2H2O. Mole weight: 520.59. Purity: 0.98. Product ID: ACM299956. Alfa Chemistry ISO 9001:2015 Certified. Categories: Medihaler-ISO.
Adrenaline Impurity 8 (Isoproterenol Impurity 4)
Adrenaline Impurity 8 (Isoproterenol Impurity 4). Uses: For analytical and research use. Group: Impurity standards. CAS No. 25015-92-3. Molecular Formula: C8H7ClO3. Mole Weight: 186.59. Catalog: APB25015923.
(-)-Isoproterenol hydrochloride
(-)-Isoproterenol (Levisoprenaline; Proternol L) hydrochloride is a β-adrenoceptor agonist. (-)-Isoproterenol induces ventricular remodeling [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Levisoprenaline hydrochloride; Proternol L hydrochloride. CAS No. 5984-95-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B1670A.
L-Isoproterenol Sulphate
The sulphate salt of isoproterenol, a β-adrenoreceptor agonist used to treat heart block. Synonyms: L-4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol Sulphate. Molecular formula: C11H19NO7S. Mole weight: 309.34.
(R)-(-)-Isoproterenol
(R)-(-)-Isoproterenol. Uses: Designed for use in research and industrial production. Appearance: Crystalline. CAS No. 51-31-0. Molecular formula: C11H17NO3. Mole weight: 211.26. Purity: 0.98. Product ID: ACM51310. Alfa Chemistry ISO 9001:2015 Certified. Categories: (R)-Isoproterenol.
17-ODYA
17-ODYA is a CYP450 ω-hydroxylase inhibitor. 17-ODYA is also a potent inhibitor (IC 50 <100 nM) of the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids by rat renal cortical microsomes incubated with arachidonic acid. 17-ODYA completely attenuates the isoproterenol (ISO)-induced apoptosis, and necrosis in cultured cardiomyocytes [1] [2] [3]. 17-ODYA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 34450-18-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101016.
8-Aminoadenine
8-Aminoadenine is an adenine receptor agonist with Ki value of 0.0341 μM in HEK293 cells expressing an adenine binding site. It shows 190-fold increased potency at the human binding site over the rat adenine receptor. It inhibits adenine uptake and isoproterenol-stimulated cAMP accumulation. It may be used in the synthetic preparation of purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase. It is important in regulating myocardial oxygen consumption and coronary blood flow. It may take part in inflammation and immune responses. Synonyms: 9H-Purine-6,8-diamine; 1H-Purine-6,8-diamine (9CI); 6,8-Diamino-purine (8CI); NSC 21698; NSC21698; NSC-21698. Grades: ≥98% by HPLC. CAS No. 28128-33-8. Molecular formula: C5H6N6. Mole weight: 150.14.
Carbuterol acetate
Carbuterol acetate hydrate is an impurity of Carbuterol. Carbuterol is a β-adrenergic agonist related to isoproterenol with selectivity for airway smooth muscle receptors used as a bronchodilator. Synonyms: [5-(2-tert-Butylamino-1-hydroxyethyl)-2-hydroxyphenyl]-urea acetate; 1-(2-Hydroxy-5-{1-hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}phenyl)urea acetate (1:1). CAS No. 1613439-57-8. Molecular formula: C13H21N3O3.C2H4O2. Mole weight: 327.38.
Carbuterol Hemisulfate Salt
A β-adrenergic agonist related to isoproterenol with selectivity for airway smooth muscle receptors. Bronchodilator. Group: Biochemicals. Alternative Names: N-[5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]urea Hemisulfate; Bronsecur; Carbuterol Hemisulfate Pirem; SKF 40383 Hemisulfate; SKF 40383A Hemisulfate. Grades: Highly Purified. CAS No. 34866-46-1. Pack Sizes: 1mg. Molecular Formula: C??H??ClN?O? 1/2 H?SO?, Molecular Weight: 303.79. US Biological Life Sciences.
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Cinepazide
Cinepazide is a vasodilator. Cinepazide (30 mg/kg, i.v.) potentiated the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, Intravertebral cinepazide(1-10 mg) increased vertebral blood flow in a dose-related manner and the effect was partially inhibited by intravenous pretreatment with aminophylline but not by pretreatment with autonomic antagonists. Cinepazide resembled cinnarizine and papaverine in that the drug antagonized rabbit aortic contraction induced by KCl, norepinephrine or CaCl2. Cinepazide in concentrations ranging from 10-6 to 10-5M augmented the relaxing responses to ATP, adenosine and cAMP. However, this agent did not affect the relaxations induced by isoproterenol and papaverine and the contractions induced by 5-HT, prostaglandin F2α and ATP. cinepazide selectively potentiates the relaxing response mediated through purinergic P1 receptors. Synonyms: Cinepazide. Grades: >98%. CAS No. 23887-46-9. Molecular formula: C22H31N3O5. Mole weight: 417.5.
Fabomotizole
Fabomotizole (CM346) is an insecticide with anxiolytic, antianxiety, and neuroprotective activities and a substrate of p-glycoprotein. Fabomotizole inhibits the ST-segment depression induced by isoproterenol in a rat model of acute subendocardial ischemia. Fabomotizole also inhibits Giardia lamblia and has the potential to inhibit giardiasis. Fabomotizole also targets Sigma1R , NRH:quinone reductase 2 (NQO2) , and MAO-A to exert anxiolytic effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM346. CAS No. 173352-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-14895.
A cell-permeable Niacin triazolo derivative that acts as a potent and selective agonist toward the human orphan G-protein-coupled receptor GPR109b/HM74, but not GPR109a/HM74A or b-adrenergic receptor. Effectively inhibits cAMP elevation induced by forskolin (5uM) and isoproterenol (1uM), respectively, in GPR109b-expressing CHO cells (EC50=400nM) and freshly isolated human adipocytes (EC50 about 1uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 306935-41-1. Pack Sizes: 25mg. US Biological Life Sciences.
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IBC 293
IBC 293, a cell-permeable niacin triazolo derivative, is a potent and highly selective agonist for human orphan G-protein-coupled receptor GPR109b/HM74 expressed in adipocytes with EC50 value of 400 nM. It is selective for GPR109B over niacin receptor GPR109A and β-adrenergic receptor. It inhibits cAMP elevation induced by isoproterenol and forskolin in freshly isolated human adipocytes and GPR109b-expressing CHO cells. It also inhibits forskolin-stimulated cAMP release in Chinese hamster ovary cells. It also inhibits isoproterenol-stimulated lipolysis in vitro in isolated human adipocytes. It may be relevant to atherosclerosis and dyslipidemia. Synonyms: IBC 293; IBC293; IBC-293. 1-Isopropyl-1,2,3-benzotriazole-5-carboxylic acid; 1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid. Grades: ≥99% by HPLC. CAS No. 306935-41-1. Molecular formula: C10H11N3O2. Mole weight: 205.22.
Isoprenaline hydrochloride
Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Isoproterenol hydrochloride. CAS No. 51-30-9. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g. Product ID: HY-B0468.
L-748,337
L-748,337 is a selective and competitive β3-adrenoceptor antagonist with Ki value of 4.0 nM. It can inhibit agonist-induced relaxation of smooth muscle and lipolysis in rhesus monkey adipocytes. It also inhibits cAMP accumulation in response to isoproterenol. It reduces apoptosis, iNOS expression and attenuates nitric oxide-induced cell proliferation in a melanoma cell line. Synonyms: L-748337; L 748337; L748337. N- [ [3- [ (2S) -2-Hydroxy-3- [ [2- [4- [ (phenylsulfonyl) amino] phenyl] ethyl] amino] propoxy] phenyl] methyl] -acetamide. Grades: ≥98% by HPLC. CAS No. 244192-94-7. Molecular formula: C26H31N3O5S. Mole weight: 497.61.
Momordicine I
Momordicine I, a triterpenoid compound extracted from momordica charantia L. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ [1]. Uses: Scientific research. Group: Natural products. CAS No. 91590-76-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-122949.
N-[5-Acetyl-2- (phenylmethoxy) phenyl]urea
N-[5-Acetyl-2- (phenylmethoxy) phenyl]urea is an intermediate used in the synthesis of Carbuterol (C183350), an β-adrenergic agonist related to isoproterenol with selectivity for airway smooth muscle receptors. Group: Biochemicals. Alternative Names: [5-Acetyl-2- (benzyloxy) phenyl]urea; [5-Acetyl-2- (phenylmethoxy) phenyl]urea. Grades: Highly Purified. CAS No. 34241-97-9. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
N-Isopropylnoradrenochrome
N-Isopropylnoradrenochrome is an impurity of Isoproterenol, which is a non-selective β-adrenoceptor agonist used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma. Synonyms: 1-Isopropylnoradrenochrome; Aludrinochrome; Isoproterenol Aminochrome; Isoproteroquinone; N-Isopropylnoradrenochrome; 2,3-Dihydro-3-hydroxy-1-(1-methylethyl)-1H-indole-5,6-dione. Grades: ≥95%. CAS No. 3736-31-0. Molecular formula: C11H13NO3. Mole weight: 207.23.
SQ-22536
SQ-22536, also known as NSC 53339, is a cell-permeable adenylyl cyclase inhibitor (IC50 = 20 μM in detergent-dispersed rat brain preparation). SQ 22536 has demonstrated inhibition of the effect of glucagon on rat membrane cyclase activity and has reduced the effect of isoproterenol, epinephrine, norepinephrine, and phenylephrine. Synonyms: 9-(tetrahydro-2-furanyl)-9H-purin-6-amine; SQ-22536; SQ22536; SQ 22536; SQ-22,536; SQ22,536; SQ 22,536. NSC 53339. CAS No. 17318-31-9. Molecular formula: C9H11N5O. Mole weight: 205.22.
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