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An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane; (7S)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine. Grade: 95%. CAS No. 866783-13-3. Molecular formula: C12H18ClNO2. Mole weight: 243.73.
2-Oxo-ivabradine Hydrochloride
2-Oxo-ivabradine Hydrochloride is an impurity of Ivabradine Hydrochloride (I940500) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Grades: Highly Purified. CAS No. 1616710-50-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H35ClN2O6. US Biological Life Sciences.
Worldwide
2-Oxo-ivabradine Hydrochloride
2-Oxo-ivabradine Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-4,5-dihydro-7,8-dimethoxy-1H-3-benzazepine-1,2(3H)-dione Hydrochloride (1:1). CAS No. 1616710-50-9. IUPAC Name: 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-1,2-dihydro-3-benzazepine-4,5-dione;hydrochloride. Molecular formula: C27H34N2O6.ClH. Mole weight: 519.03. Catalog: APS1616710509. SMILES: Cl.COc1cc2C[C@H](CN(C)CCCN3CCc4cc(OC)c(OC)cc4C(=O)C3=O)c2cc1OC. Format: Neat.
3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one is an impurity in the synthesis of Ivabradine (I940500), a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Grades: Highly Purified. CAS No. 85175-65-1. Pack Sizes: 100mg, 1g. Molecular Formula: C15H20ClNO3, Molecular Weight: 297.779999999999. US Biological Life Sciences.
3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one is an impurity in the synthesis of Ivabradine (I940500), a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C15H14D6ClNO3, Molecular Weight: 303.81. US Biological Life Sciences.
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-(3-chloropropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one; 3-(3-chloropropyl)-7,8-dimethoxy-2,3-dihydro-1H-3-benzazepin-2-one; 3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one. Grade: 95%. CAS No. 85175-59-3. Molecular formula: C15H18ClNO3. Mole weight: 295.76.
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 3-(3-Hydroxypropyl)-7,8-dimethoxy-1,3-dihydro-2h-benzo[d]azepin-2-one; Ivabradine Impurity H. CAS No. 1235547-06-4. Molecular formula: C15H19NO4. Mole weight: 277.31.
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Synonyms: 7,8-Dimethoxy-1,2-dihydro-3H-3-benzazepin-2-one. Grade: 95%. CAS No. 73942-87-7. Molecular formula: C12H13NO3. Mole weight: 219.24.
Hydroxy Ivabradine
An impurity of Ivabradine, a medication used to reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure. Synonyms: 1,3,4,5-Tetrahydro-3-(3-hydroxypropyl)-7,8-dimethoxy-2H-3-benzazepin-2-one; 3-(3-Hydroxypropyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one. Grade: > 95%. CAS No. 1235547-07-5. Molecular formula: C15H21NO4. Mole weight: 279.34.
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