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| Product | Description | |
|---|---|---|
| Ivacaftor | Ivacaftor. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX 770. Grades: Highly Purified. CAS No. 873054-44-5. Pack Sizes: 5mg. Molecular Formula: C24H28N2O3, Molecular Weight: 392.49. US Biological Life Sciences. |  Worldwide |
| Ivacaftor | Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Ivacaftor is used in the treatment of cystic fibrosis. Uses: Chloride channel agonists. Synonyms: N-[2,4-Bis[1,1-di(methyl)ethyl]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX-770; VX 770; VX770. Grades: 98%. CAS No. 873054-44-5. Molecular formula: C24H28N2O3. Mole weight: 392.49. |  |
| Ivacaftor | Ivacaftor. Uses: For analytical and research use. Group: Impurity standards. CAS No. 873054-44-5. Molecular Formula: C24H28N2O3. Mole Weight: 392.5. Catalog: APB873054445. |  |
| Ivacaftor | Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC 50 s of 100 nM and 25 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-770. CAS No. 873054-44-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13017. |  |
| Ivacaftor Acyl-Glucuronide | Ivacaftor Acyl-Glucuronide is an impurity of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Molecular formula: C30H34N2O10. Mole weight: 582.60. | |
| Ivacaftor Benzenesulfonate | Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Synonyms: N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide Benzenesulfonate;N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide Benzenesulfonate; VX-770; VX 770; VX770. Grades: 98%. CAS No. 1134822-09-5. Molecular formula: C30H34N2O6S. Mole weight: 550.66. | |
| Ivacaftor Carboxylic Acid | Ivacaftor Carboxylic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-α,α-dimethyl-, 2-(5-tert-Butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid, 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-α,α-dimethylbenzeneacetic acid, Ivacaftor carboxylic acid, Ivacaftor impurity 1. CAS No. 1246213-24-0. IUPAC Name: 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid. Molecular Formula: C24H26N2O5. Mole Weight: 422.47. Catalog: APS1246213240. SMILES: CC (C) (C)c1cc (c (O)cc1NC (=O)C2=CNc3ccccc3C2=O)C (C) (C)C (=O)O. Format: Neat. | |
| Ivacaftor Carboxylic Acid Lactone | Ivacaftor Carboxylic Acid Lactone is related to Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Synonyms: N-[5-(1,1-Dimethylethyl)-2,3-dihydro-3,3-dimethyl-2-oxo-6-benzofuranyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; N-(5-(tert-Butyl)-3,3-dimethyl-2-oxo-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide. Grades: ≥95%. CAS No. 1246213-41-1. Molecular formula: C24H24N2O4. Mole weight: 404.46. | |
| Ivacaftor Carboxylic Acid N-Glucuronide | Ivacaftor Carboxylic Acid N-Glucuronide is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Grades: 95%. Molecular formula: C30H34N2O11. Mole weight: 598.60. | |
| Ivacaftor Carboxylic Acid O-Glucuronide | Ivacaftor Carboxylic Acid O-Glucuronide is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Molecular formula: C30H34N2O11. Mole weight: 598.60. | |
| Ivacaftor-d18 | Ivacaftor-d18. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide-d18. Grades: Highly Purified. CAS No. 1413431-05-6. Pack Sizes: 2.5mg. Molecular Formula: C24H10D18N2O3, Molecular Weight: 410.6. US Biological Life Sciences. | Worldwide |
| Ivacaftor-d19 | Ivacaftor-d 9 is a potent CFTR modulator and exhibits an EC 50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: VX-770-d19. CAS No. 1413431-22-7. Pack Sizes: 5 mg; 1 mg. Product ID: HY-13017S1. | |
| Ivacaftor hydrate | Ivacaftor hydrate is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively. Synonyms: VX-770 hydrate; N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrate; 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-, hydrate (1:1); N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide hydrate (1:1); Kalydeco hydrate. Grades: >98%. CAS No. 1134822-07-3. Molecular formula: C24H30N2O4. Mole weight: 410.51. | |
| Ivacaftor impurities1 | Ivacaftor impurities1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 873051-52-6. Molecular Formula: C24H28N2O3. Mole Weight: 392.5. Catalog: APB873051526. | |
| Ivacaftor impurities10 | Ivacaftor impurities10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 26892-90-0. Molecular Formula: C12H11NO3. Mole Weight: 217.22. Catalog: APB26892900. | |
| Ivacaftor impurities11 | Ivacaftor impurities11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13721-01-2. Molecular Formula: C10H7NO3. Mole Weight: 189.17. Catalog: APB13721012. | |
| Ivacaftor impurities 12 | Ivacaftor impurities 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 873055-58-4. Molecular Formula: C14H23NO. Mole Weight: 221.34. Catalog: APB873055584. | |
| Ivacaftor impurities 13 | Ivacaftor impurities 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H27N3O4. Mole Weight: 421.5. Catalog: APB11131. | |
| Ivacaftor impurities 14 | Ivacaftor impurities 14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H27N3O4. Mole Weight: 421.5. Catalog: APB11132. | |
| Ivacaftor impurities 15 | Ivacaftor impurities 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C10H6N2O4. Mole Weight: 218.17. Catalog: APB11134. | |
| Ivacaftor impurities 16 | Ivacaftor impurities 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H10N2O4. Mole Weight: 246.22. Catalog: APB11133. | |
| Ivacaftor impurities 17 | Ivacaftor impurities 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2760759-55-3. Molecular Formula: C34H33N3O5. Mole Weight: 563.65. Catalog: APB2760759553. | |
| Ivacaftor impurities2 | Ivacaftor impurities2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 873054-39-8. Molecular Formula: C20H20N2O3. Mole Weight: 336.39. Catalog: APB873054398. | |
| Ivacaftor impurities3 | Ivacaftor impurities3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 873055-35-7. Molecular Formula: C10H15NO. Mole Weight: 165.24. Catalog: APB873055357. | |
| Ivacaftor impurities4 | Ivacaftor impurities4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1643-39-6. Molecular Formula: C14H23NO. Mole Weight: 221.34. Catalog: APB1643396. | |
| Ivacaftor impurities5 | Ivacaftor impurities5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-24-0. Molecular Formula: C24H26N2O5. Mole Weight: 422.48. Catalog: APB1246213240. | |
| Ivacaftor impurities6 | Ivacaftor impurities6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-23-9. Molecular Formula: C24H28N2O4. Mole Weight: 408.5. Catalog: APB1246213239. | |
| Ivacaftor impurities7 | Ivacaftor impurities7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246213-41-1. Molecular Formula: C24H24N2O4. Mole Weight: 404.47. Catalog: APB1246213411. | |
| Ivacaftor impurities8 (Kynurenic Acid Impurity 4) | Ivacaftor impurities8 (Kynurenic Acid Impurity 4). Uses: For analytical and research use. Group: Impurity standards. CAS No. 34785-11-0. Molecular Formula: C10H7NO3. Mole Weight: 189.17. Catalog: APB34785110. | |
| Ivacaftor impurities9 | Ivacaftor impurities9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 83342-70-5. Molecular Formula: C10H7NO2. Mole Weight: 173.17. Catalog: APB83342705. | |
| Ivacaftor Impurity 1 | an impurity of Ivacaftor. Synonyms: Ivacaftor Carboxylic Acid; 4-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-5-(1,1-dimethylethyl)-2-hydroxy-α,α-dimethylbenzeneacetic Acid. Grades: > 95%. CAS No. 1246213-24-0. Molecular formula: C24H26N2O5. Mole weight: 422.49. | |
| Ivacaftor Impurity 2 | an impurity of Ivacaftor. Synonyms: Hydroxymethyl Ivacaftor; N-[2-(1,1-Dimethylethyl)-5-hydroxy-4-(2-hydroxy-1,1-dimethylethyl)phenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide. Grades: > 95%. CAS No. 1246213-23-9. Molecular formula: C24H28N2O4. Mole weight: 408.50. | |
| Ivacaftor N-Glucuronide | Ivacaftor N-Glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C30H36N2O9, Molecular Weight: 568.61. US Biological Life Sciences. | Worldwide |
| Ivacaftor-N-Glucuronide | Ivacaftor-N-Glucuronide is a metabolite of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: Ivacaftor N-β-D-Glucuronide. Grades: 98%. Molecular formula: C30H36N2O9. Mole weight: 568.61. | |
| Ivacaftor-O-Glucuronide | Ivacaftor-O-Glucuronide is a metabolite of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: Ivacaftor O-β-D-Glucuronide. Grades: 98%. Molecular formula: C30H36N2O9. Mole weight: 568.61. | |
| Hydroxymethyl Ivacaftor | Hydroxymethyl Ivacaftor. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS001947. Format: Neat. | |
| 1,4-Dihydro-4-oxo-3-quinolinecarbonyl Chloride | 1,4-Dihydro-4-oxo-3-quinolinecarbonyl Chloride is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: 4-Oxo-1,4-dihydroquinoline-3-carbonyl Chloride. CAS No. 80761-61-1. Molecular formula: C10H6ClNO2. Mole weight: 207.61. | |
| 2,4-Di-tert-butyl-5-nitrophenyl-d10 Methyl Carbonate | 5-Nitro-2,4-bis(1,1-dimethylethyl)phenyl-carbonic Acid Methyl Ester-d10 is an intermediate used in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603), which is isotopically labeled form of Ivacaftor (I940600), that is used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C16H13D10NO5, Molecular Weight: 319.42. US Biological Life Sciences. | Worldwide |
| 2,4-Di-tert-butyl-6-nitrophenyl Methyl Carbonate + 2,4-Di-tert-butyl-5-nitrophenyl Methyl Carbonate (Mixture of Regioisomers) | 2,4-Di-tert-butyl-6-nitrophenyl Methyl Carbonate + 2,4-Di-tert-butyl-5-nitrophenyl Methyl Carbonate (Mixture of Regioisomers) is an intermediate of Ivacaftor, a drug used in the treatment of cystic fibrosis. Molecular formula: C16H23NO5. Mole weight: 309.36. | |
| 2,4-Di-tert-butyl-6-nitrophenyl Methyl Carbonate + 2,4-Di-tert-butyl-5-nitrophenyl Methyl Carbonate. (Mixture of Regioisomers) | 2,4-Di-tert-butyl-6-nitrophenyl Methyl Carbonate + 2,4-Di-tert-butyl-5-nitrophenyl Methyl Carbonate (Mixture of Regioisomers) is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H23NO5 + C16H23NO5. US Biological Life Sciences. | Worldwide |
| 2,4-Di-tert-butylphenol-d10 | 2,4-Di-tert-butylphenol-d10 is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. 2,4-Di-tert-butylphenol-d18 is the labelled analogue of 2,4-Di-tert-butylphenol (D429475). A chemical constituent of volatile oils from Catunaregam spinosa fruits. Group: Biochemicals. Grades: Highly Purified. CAS No. 1577233-50-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C14H12D10O. US Biological Life Sciences. | Worldwide |
| 2-Bromo-4-(1,1-dimethylethyl)-5-nitrophenol | 2-Bromo-4-(1,1-dimethylethyl)-5-nitrophenol is a metabolite of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: 2-Bromo-4-(2-methyl-2-propanyl)-5-nitrophenol; Phenol, 2-bromo-4-(1,1-dimethylethyl)-5-nitro-; 2-Bromo-4-tert-butyl-5-nitro-phenol. Grades: ≥95%. CAS No. 1246213-42-2. Molecular formula: C10H12BrNO3. Mole weight: 274.11. | |
| 2-Bromo-4-(tert-butyl)-5-nitrophenyl Acetate | 2-Bromo-4-(tert-butyl)-5-nitrophenyl Acetate is an intermediate in the synthesis of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Molecular formula: C12H14BrNO4. Mole weight: 316.15. | |
| 3-Amino-4-(1,1-dimethylethyl)-6-[1,1-di(methyl-d3)ethyl-2,2,2-d3]phen-2-d-ol | 3-Amino-4-(1,1-dimethylethyl)-6-[1,1-di(methyl-d3)ethyl-2,2,2-d3]phen-2-d-ol is an intermediate used in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603), which is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1577233-53-4. Pack Sizes: 500ug, 1mg. Molecular Formula: C14H13D10NO, Molecular Weight: 231.4. US Biological Life Sciences. | Worldwide |
| 5-(1,1-Dimethylethyl)-3,3-dimethyl-6-nitro-2(3H)-benzofuranone | 5-(1,1-Dimethylethyl)-3,3-dimethyl-6-nitro-2(3H)-benzofuranone is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: 5-(tert-butyl)-3,3-dimethyl-6-nitrobenzo[b]furan-2(3H)-one. CAS No. 1246213-39-7. Molecular formula: C14H17NO4. Mole weight: 263.29. | |
| 5-Amino-2,4-di-tert-butylphenol | 5-Amino-2,4-di-tert-butylphenol is an intermediate of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: 5-Amino-2,4-bis(1,1-dimethylethyl)phenol; 5-Amino-2,4-bis(2-methyl-2-propanyl)phenol; Phenol, 5-amino-2,4-bis(1,1-dimethylethyl)-. Grades: ≥95%. CAS No. 873055-58-4. Molecular formula: C14H23NO. Mole weight: 221.34. | |
| 5-Amino-2,4-di-tert-butylphenol-d9 | 5-Amino-2,4-di-tert-butylphenol-d9 is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1577233-54-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H14D9NO. US Biological Life Sciences. | Worldwide |
| 6-Amino-2,4-di-tert-butylphenyl Methyl Carbonate | 6-Amino-2,4-di-tert-butylphenyl Methyl Carbonate is an intermediate of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: 2-amino-4,6-di-tert-butylphenyl methyl carbonate; 2-Amino-4,6-bis(2-methyl-2-propanyl)phenyl methyl carbonate; Carbonic acid, 2-amino-4,6-bis(1,1-dimethylethyl)phenyl methyl ester. Molecular formula: C16H25NO3. Mole weight: 279.37. | |
| 6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone | 6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone is an intermediate in the synthesis of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Synonyms: 6-Amino-5-(tert-butyl)-3,3-dimethylbenzofuran-2(3H)-one; 2(3H)-Benzofuranone, 6-amino-5-(1,1-dimethylethyl)-3,3-dimethyl-; 6-Amino-3,3-dimethyl-5-(2-methyl-2-propanyl)-1-benzofuran-2(3H)-one; 6-Amino-5-(tert-butyl)-3,3-dimethylbenzo[b]furan-2(3H)-one. Grades: ≥95%. CAS No. 1246213-40-0. Molecular formula: C14H19NO2. Mole weight: 233.31. | |
| Methyl 2-(2-Acetoxy-5-(tert-butyl)-4-nitrophenyl)-2-methylpropanoate | Methyl 2-(2-Acetoxy-5-(tert-butyl)-4-nitrophenyl)-2-methylpropanoate is an intermediate in the synthesis of Ivacaftor, which is a CFTR potentiator used in the treatment of cystic fibrosis. Molecular formula: C17H23NO6. Mole weight: 337.37. | |
| N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide | N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide is an intermediate of Ivacaftor, a drug used in the treatment of cystic fibrosis. Synonyms: Carbonic Acid 5-[[(1,4-Dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl Methyl Ester; 2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl methyl carbonate; 2,4-Bis(2-methyl-2-propanyl)-5-{[(4-oxo-1,4-dihydro-3-quinolinyl)carbonyl]amino}phenyl methyl carbonate. Grades: ≥95%. CAS No. 1246213-45-5. Molecular formula: C26H30N2O5. Mole weight: 450.53. | |
| N-(5-(tert-Butyl)-2-hydroxy-3,3-dimethyl-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide | N-(5-(tert-Butyl)-2-hydroxy-3,3-dimethyl-2,3-dihydrobenzofuran-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide is an impurity of Ivacaftor, a drug used in the treatment of cystic fibrosis. Molecular formula: C24H26N2O4. Mole weight: 406.47. | |
| Tezacaftor | Tezacaftor (VX-661) is a F508del CFTR corrector. It helps CFTR protein reach the cell surface. However, Ivacaftor (VX-770, HY-13017), a CFTR potentiator, helps to prolong the opening time of cell surface CFTR protein channels. Tezacaftor combining with Ivacaftor, shows potent efficacy against cystic fibrosis and diseases with homozygous for the CFTR Phe508del mutation. Moreover, Elexacaftor (VX-445, HY-111772) is also a CFTR corrector. Elexacaftor-Tezacaftor-Ivacaftor aims at with cystic fibrosis (CF) with at least one Phe508del mutation, often avoids the indication for lung transplantation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-661. CAS No. 1152311-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15448. | |
| VX-661 | VX-661 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used in combination with Ivacaftor in the treatment of cystic fibrosis. Synonyms: 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide; VX 661; VX661; Tezacaftor. Grades: 98%. CAS No. 1152311-62-0. Molecular formula: C26H27F3N2O6. Mole weight: 520.50. | |
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