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Ivermectin aglycone is a semi-synthetic produced by the hydrolysis of the disaccharide unit of ivermectin. Ivermectin aglycone is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 aglycone,Ivermectin B1 aglycone. Grades: Highly Purified. CAS No. 123997-59-1. Pack Sizes: 1mg. US Biological Life Sciences.
Ivermectin B1a is the major component (>80%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides. The individual 25-sec-butyl (B1a) and 25-iso-propyl (B1b) components of ivermectin have received little separate study. Group: Biochemicals. Alternative Names: Ivermectin, Ivermectin B1a, 22, 23-Dihydro-avermectin B1a. Grades: Highly Purified. CAS No. 70161-11-4. Pack Sizes: 1mg. US Biological Life Sciences.
Ivermectin monosaccharide is a semi-synthetic produced by the selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 monosaccharide, Ivermectin B1 monosaccharide. Grades: Highly Purified. CAS No. 123997-64-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivermectin
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Synonyms: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). Grades: ≥95%. CAS No. 70288-86-7. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16.
Ivermectin
Ivermectin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 70288-86-7. Molecular Formula: C48H74O14. Mole Weight: 875.11. Catalog: APB70288867.
Ivermectin
Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1; 22,23-Dihydro C-076B1; Heartgard 30; Ivomec; Ivosint; Mectizan; Stromectol; Uvemec; Vermic; Zimecterin. Grades: Highly Purified. CAS No. 70288-86-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Ivermectin
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C48H74O14. CAS No. 70288-86-7. Prepack ID 21022571-1g. Molecular Weight 875.09. See USA prepack pricing.
Ivermectin 2-epimer
an epimer of Ivermectin. Synonyms: 2-epi-Ivermectin B1a. Grades: > 95%. Molecular formula: C48H74O14. Mole weight: 875.12.
Ivermectin B1a
Ivermectin B1a is a major component of Ivermectin, a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Group: Biochemicals. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a; 2,23-Dihydroavermectin B1a; Dihydroavermectin B1a. Grades: Highly Purified. CAS No. 71827-03-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 875.09. US Biological Life Sciences.
Worldwide
Ivermectin B1a
It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Synonyms: Dihydroavermectin B1a; Ivermectin; 22,23-Dihydroavermectin B1a; 5-O-Demethyl-22,23-dihydro-avermectin A1a; Ivermectin Impurity I. Grades: >95% by HPLC. CAS No. 70161-11-4. Molecular formula: C48H74O14. Mole weight: 875.12.
Ivermectin B1a-D2
Ivermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C48H72D2O14, Molecular Weight: 877.11. US Biological Life Sciences.
Worldwide
Ivermectin B1 Aglycon
Ivermectin B1 Aglycon. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-, (6R,13S,25R)-,(6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B, 22,23-Dihydroavermectin B1a Aglycon, Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Milbemycin B Deriv., Ivermectin Imp. G (EP), Ivermectin Aglycone, [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B. CAS No. 73162-95-5. Pack Sizes: 1MG. Molecular Formula: C34H50O8. Mole Weight: 586.76. Catalog: APS73162955. SMILES: CC[C@H] (C)[C@H]1O[C@]2 (CC[C@@H]1C)C[C@@H]3C[C@@H] (C\C=C (/C)\[C@@H] (O)[C@@H] (C)\C=C\C=C\4/CO[C@@H]5[C@H] (O)C (=C[C@@H] (C (=O)O3)[C@]45O)C)O2. Format: Neat. Shipping: Room Temperature.
Ivermectin B1 Aglycon
Ivermectin B1 Aglycon is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 73162-95-5. Pack Sizes: 50mg, 500mg. Molecular Formula: C34H50O8. US Biological Life Sciences.
Worldwide
Ivermectin B1 aglycone
A semi-synthetic product produced by hydrolysing the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 aglycone; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; 22,23-Dihydroavermectin B1a Aglycon; Ivermectin Aglycone; 13-O-De[4-O-(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl]-22,23-dihydro-27-noravermectin A1. Grades: >99% by HPLC. CAS No. 123997-59-1. Molecular formula: C34H50O8. Mole weight: 586.76.
Ivermectin B1b
Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Synonyms: Dihydroavermectin B1b; 22,23-Dihydroavermectin B1b; Avermectin H2B1b. Grades: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C47H72O14. Mole weight: 861.06.
Ivermectin B1b
Ivermectin B1b is the minor component (>20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro tests have found the B1b (25-iso-propyl) analogue to be slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis and also a more sensitive probe for ivermectin resistance. Group: Biochemicals. Alternative Names: Ivermectin B1b, 22, 23-Dihydroavermectin B1b. Grades: Highly Purified. CAS No. 70209-81-3. Pack Sizes: 500ug, 2.5mg. US Biological Life Sciences.
Worldwide
Ivermectin B1B
Ivermectin B1B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 70209-81-3. Molecular Formula: C47H72O14. Mole Weight: 861.08. Catalog: APB70209813.
Ivermectin B1 Monosaccharide
Ivermectin B1 Mono-sugar Derivative is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 71837-27-9. Pack Sizes: 50mg, 500mg. Molecular Formula: C41H62O11. US Biological Life Sciences.
Worldwide
Ivermectin-d2
Isotope labelled Ivermectin, is the labeled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivermectin EP Impurity C
Ivermectin EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 65195-57-5. Molecular Formula: C48H74O15. Mole Weight: 891.11. Catalog: APB65195575.
Ivermectin impurity 10
Ivermectin impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1135339-49-9. Molecular Formula: C48H74O14. Mole Weight: 875.11. Catalog: APB1135339499.
Ivermectin impurity 11
Ivermectin impurity 11. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C47H72O14. Mole Weight: 861.08. Catalog: APB11124.
Ivermectin impurity 12
Ivermectin impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 74567-01-4. Molecular Formula: C48H76O14. Mole Weight: 877.12. Catalog: APB74567014.
Ivermectin impurity 13
Ivermectin impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H76O14. Mole Weight: 889.13. Catalog: APB11125.
Ivermectin impurity 14
Ivermectin impurity 14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H76O15. Mole Weight: 905.13. Catalog: APB11126.
Ivermectin impurity 15
Ivermectin impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C47H72O14. Mole Weight: 861.08. Catalog: APB11127.
Ivermectin impurity 16
Ivermectin impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 431070-70-1. Molecular Formula: C47H72O14. Mole Weight: 861.08. Catalog: APB431070701.
Ivermectin impurity 17
Ivermectin impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 127468-07-9. Molecular Formula: C48H74O15. Mole Weight: 891.11. Catalog: APB127468079.
Ivermectin impurity 18
Ivermectin impurity 18. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H76O15. Mole Weight: 905.13. Catalog: APB11128.
Ivermectin impurity 5
Ivermectin impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102190-55-6. Molecular Formula: C48H72O15. Mole Weight: 889.09. Catalog: APB102190556.
Ivermectin impurity 6
Ivermectin impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H76O14. Mole Weight: 889.13. Catalog: APB11122.
Ivermectin impurity 7
Ivermectin impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H74O14. Mole Weight: 875.11. Catalog: APB11123.
Ivermectin impurity 8
Ivermectin impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 73162-95-5. Molecular Formula: C34H50O8. Mole Weight: 586.77. Catalog: APB73162955.
Ivermectin impurity 9
Ivermectin impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 71837-27-9. Molecular Formula: C41H62O11. Mole Weight: 730.94. Catalog: APB71837279.
Ivermectin Impurity D
an impurity of Ivermectin. Synonyms: 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.10.
Ivermectin Impurity G
an impurity of Ivermectin. Synonyms: Ivermectin B1 Aglycon; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B. Grades: > 95%. CAS No. 73162-95-5. Molecular formula: C34H50O8. Mole weight: 586.77.
Ivermectin Impurity H
an impurity of Ivermectin. Synonyms: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94.
Ivermectin Impurity K
an impurity of Ivermectin. Synonyms: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13.
Ivermectin monosaccharide
A semi-synthetic product produced by selective hydrolysis of the terminal saccharide unit. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. It is a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)ivermectin B1. Grades: >99% by HPLC. CAS No. 123997-64-8. Molecular formula: C41H62O11. Mole weight: 730.92.
Ivermectin USP
Ivermectin USP.
CA, FL & NJ
2,3-Dehydro-3,4-dihydro Ivermectin
2,3-Dehydro-3,4-dihydro Ivermectin is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: Ivermectin EP Impurity I; (4S)-2,3-Didehydro-5-O-demethyl-3,4,22,23-tetrahydroavermectin A1a. Grades: ≥95%. CAS No. 1135339-49-9. Molecular formula: C48H74O14. Mole weight: 875.1.
2,3-Dehydro-3,4-dihydro Ivermectin (Mixture of Diastereomers)
2,3-Dehydro-3,4-dihydro Ivermectin is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 1135339-49-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C48H74O14. US Biological Life Sciences.
Worldwide
28-Oxo Ivermectin B1a (Impurity)
28-Oxo Ivermectin B1a is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 102190-55-6. Pack Sizes: 5mg, 50mg. Molecular Formula: C48H72O15. US Biological Life Sciences.
Worldwide
2-epi-Ivermectin B1a
2-epi-Ivermectin B1a is an epimer of Ivermectin, semi-synthetic derivative of Abamectin. Ivermectin is a broad-spectrum antiparasitic agent, traditionally against parasitic worms. It is mainly used in humans in the treatment of onchocerciasis (river blindness), but is also effective against other worm infestations. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C48H74O14. US Biological Life Sciences.
Worldwide
3,4-Dihydro Ivermectin (Mixture of Diastereomers)
3,4-Dihydro Ivermectin is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 74567-01-4. Pack Sizes: 1mg. Molecular Formula: C48H76O14. US Biological Life Sciences.
7-O-Methyl Ivermectin B1a is an impurity of Ivermectin (I940800), which is anthelmintic drug. Related to Ivermectin B1a (I940815). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C49H76O14, Molecular Weight: 889.12. US Biological Life Sciences.
Worldwide
Delta-2-Ivermectin B1a
An irreversible base degradation product of ivermectin found in animals treated with ivermectin and in the environment. It is an anthelmintic in animal health. Synonyms: Δ2-Ivermectin B1a; Ivermectin B1a, delta2-. Grades: >95% by HPLC. Molecular formula: C48H74O14. Mole weight: 875.09.
epi-Ivermectin B1a
Epi-Ivermectin B1a is a degradation product produced by the reversible base-catalyzed isomerization of ivermectin B1a. It is less active than ivermectin against T. urticae (LC90s = 4.0 and 0.038 ppm, respectively). Synonyms: 5-O-demethyl-22,23-dihydro-avermectin A1a; 2-dehydro-4-dihydro Avermectin B1a; epi-dihydro Avermectin B1a; 22,23-dihydro Avermectin B1a; 2-epi-Ivermectin B1a. Grades: >95% by HPLC. Molecular formula: C48H74O14. Mole weight: 875.09.
5-O-Demethyl-4'', 5-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-22, 23-dihydro-28-oxo-Avermectin A1a is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 102190-51-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C60H100O15Si2. US Biological Life Sciences.
5-O-Demethyl-4'', 5-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-22, 23-dihydro-Avermectin A1a is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 82590-57-6. Pack Sizes: 5mg, 25mg. Molecular Formula: C60H102O14Si2. US Biological Life Sciences.
Worldwide
Adsorbent Resin for Macromolecule adsorption,MC:45.0-55.0%
Adsorbent Resin for Macromolecule adsorption,MC:45.0-55.0%. Uses: ·Absorption of avermectin, ivermectin, erythromycin ·Extraction and separation of antibiotics and Chinese herbal medicine ·Plasma separation and purification ·Organic wastewater treatment. Group: Adsorbent Resin.
Adsorbent Resin for Protein adsorption,MC:45-55%
Adsorbent Resin for Protein adsorption,MC:45-55%. Uses: ·Absorption of avermectin, ivermectin, erythromycin and their series of products ·Extraction and separation of ginkgo, antibiotics and Chinese herbal medicine ·Plasma separation and purification ·Preparation of stationary phase for enrichment of trace elements ·Organic wastewater treatment. Group: Adsorbent Resin.
Avermectin A1a
Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10.
Avermectin A2a
Avermectin A2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a had the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22,23-dihydroabamectin B1a (above 80%) and 22,23 dioxabamectin B1b(below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: Avermectin A1a; SCHEMBL1681224. CAS No. 50914-15-3. Molecular formula: C49H76O15. Mole weight: 905.12.
Avermectin B2a
Avermectin B2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681286. CAS No. 65195-57-5. Molecular formula: C48H74O15. Mole weight: 891.09.
delta2-Avermectin B1a
Δ2-Avermectin B1a is a degradation product produced by the reversible base-catalyzed isomerization of ivermectin B1a. It is less active than ivermectin against T. urticae (LC90s = 0.23 and 0.038 ppm, respectively). Synonyms: Avermectin A1a, 2,3-didehydro-5-O-demethyl-3,4-dihydro-, (4S)-; Δ2-4(R)-avermectin B1a; Δ2-Avermectin B1a. Grades: >95% by HPLC. CAS No. 110415-68-4. Molecular formula: C48H72O14. Mole weight: 873.07.