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KN 62 1-[N,O-bis(5-Isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine, (S)-5-Isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester C38H35N5O6S2Fw 721.88 98% white solid, selectively inhibits rat brain, Ca2+/cadmodulin-dependent protein kinase II, soluble in DMSO, MeOH. selectively inhibits rat brain Ca2+/cadmodulin-dependent protein kinase II. CAS No. 127191-97-3. Product ID: 1-01108. Molecular formula: C38H35N5O6S2. Mole weight: 721.88. Purity: 0.98. Properties: white solid, soluble in DMSO, MeOH, 4°C. Reference: J. Biol. Chem., 267, 12511, 1992; J. Biol. Chem., 265, 4315, 1990. Categories: KN-62. CarboMer Inc
KN62 KN62 is a P2X7R antagonist (hP2X7 IC50=51 nM) and Ca2+/calmodulin-dependent protein kinase II inhibitor. KN62 inhibits the invasiveness of cancer cells in vitro and in vivo KN62 causes retrograde amnesia in the rat. KN62 attenuates glutamate release by inhibiting voltage-dependent Ca(2+)-channels. The effect of KN62 on Ca(2+)-influx appears to be specific to slowly-or non-inactivating conductances, and therefore presents KN62 as a potentially useful tool. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KN62; KN-62; KN 62. Product Category: Antagonists. Appearance: Solid powder. CAS No. 127191-97-3. Molecular formula: C38H35N5O6S2. Mole weight: 721.85. Purity: >98%. IUPACName: (S)-4-(2-(N-methylisoquinoline-5-sulfonamido)-3-oxo-3-(4-phenylpiperazin-1-yl)propyl)phenyl isoquinoline-5-sulfonate. Canonical SMILES: CN([C@@H](CC1=CC=C(OS(=O)(C2=C3C(C=NC=C3)=CC=C2)=O)C=C1)C(N4CCN(C5=CC=CC=C5)CC4)=O)S(C6=CC=CC7=C6C=CN=C7)(=O)=O. Product ID: ACM127191973. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
KN-62 KN-62 suppresses the A23187-induced autophosphorylation of Ca2+/CaM kinase in PC12 D cells. Uses: Enzyme inhibitors. Synonyms: KN-62; KN 62; KN62. Grades: >98%. CAS No. 127191-97-3. Molecular formula: C38H35N5O6S2. Mole weight: 721.84. BOC Sciences 10
2-Propynal 2-Propynal is hypothesized to be a possible metabolite of pargyline, a monoamine oxidase inhibitor that is used as an antihypertensive agent. 2-Propynal is also known to induce hepatocyte toxicity in vivo in rats. Group: Biochemicals. Grades: Highly Purified. CAS No. 624-67-9. Pack Sizes: 100mg, 500mg. Molecular Formula: C3H2O. US Biological Life Sciences. USBiological 10
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3,3',5-Triiodothyroacetic acid Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue. Synonyms: 2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid. Grades: 97 %. CAS No. 51-24-1. Molecular formula: C14H9I3O4. Mole weight: 621.93. BOC Sciences 6
6-Acetoxy-2H-pyran-3(6H)-one Intermediate in the preparation of 3-Methyl 2H-Furo[2,3-c]pyran-2-one also known as “karrik”, a compound found in smoke responsible for promoting seed germination. Group: Biochemicals. Alternative Names: 2-Acetoxy-5-oxo-5,6-dihydro-2H-pyran; 6-Acetoxy-2H-pyran-3(6H)-one. Grades: Highly Purified. CAS No. 62644-49-9. Pack Sizes: 250mg. US Biological Life Sciences. USBiological 1
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6-Amino-1-methyl-5-nitrosouracil 6-Amino-1-methyl-5-nitrosouracil is known to exhibit anitmicrobial activity and form complexation with platinum (II). Group: Biochemicals. Alternative Names: 6-Amino-1-methyl-5-nitroso-2,4-pyrimidinedione; 6-amino-1-methyl-5-nitroso-uracil; 6-Amino-1-methyl-5-nitrosopyrimidine-2,4-dione; NSC 62582. Grades: Highly Purified. CAS No. 6972-78-7. Pack Sizes: 10g. US Biological Life Sciences. USBiological 2
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7'-t-Butyldimethylsilyloxy-N-trityl-morpholinoguanine 7'-t-Butyldimethylsilyloxy-N-trityl-morpholinoguanine, a remarkable and potent compound harnessed in the realm of biomedicine, exhibits immense potential for combating a myriad of ailments. Known for its distinctive and intricate chemical architecture, this compound possesses the ability to selectively target and impede key enzymes implicated in the advancement of particular malignancies, including leukemia and solid tumors. Grades: ≥95%. CAS No. 2305415-90-9. Molecular formula: C35H42N6O3Si. Mole weight: 622.83. BOC Sciences 2
8-[(6-Amino)hexyl]-amino-ATP - ATTO-620 ATTO-620 is a highly effective fluorescent dye known for its meticulous labeling of biomolecules comprising a number of previously insurmountable substances such as proteins, nucleotides, and antibodies in the field of biomedical research. This extraordinary dye radiates emissions solely in the near-infrared spectrum championing its relevance in immunohistochemistry as well as in vivo imaging research. Additionally, this product has played a vital role in studying life-altering diseases such as cancer, Alzheimer's disease, and infectious diseases, igniting a new wave of scientific research. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-5'-triphosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H30N7O13P3- ATTO 620 (free acid). Mole weight: 1114.37 (free acid). BOC Sciences 2
8-[(6-Amino)hexyl]-amino-cAMP - ATTO-620 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-620, an exemplary fluorescent labeling probe essential in shedding light on cAMP signaling pathways, is widely used in biomedical research. Labeling of cell membranes and intracellular compartments using this product is indeed suitable, thereby amplifying knowledge about biomedical mechanisms of interest. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O6P - ATTO 620 (free acid). Mole weight: 936.39 (free acid). BOC Sciences 2
Acid blue 140 Acid Blue 140, also known as C.I. Acid Blue 140 or Acid Blue 140 (C.I. 62115), is a synthetic dye commonly used in the textile industry. It belongs to the class of triaryl methane dyes and is known for its bright blue color. Uses: Acid blue 140 has been used in various scientific research applications due to its unique properties. it has been used as a ph indicator in analytical chemistry, where it changes color depending on the ph of the solution. it has also been used as a fluorescent probe in biological imaging studies, where it can be used to label proteins and other biomolecules. in addition, acid blue 140 has been used as a model compound in photocatalytic studies, where it can be used to study the degradation of organic pollutants under visible light irradiation. Additional or Alternative Names: Acid Blue 140;C.I. Acid Blue 140. Product Category: Heterocyclic Organic Compound. CAS No. 12219-21-5. Molecular formula: C41H28N4O10S2·2Na. Mole weight: 844.786. Purity: 0.95. ECNumber: 247-287-0. Product ID: ACM12219215. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Acid Blue 147. Alfa Chemistry.
ACID BLUE 41 Acid blue 41 is a synthetic dye. It is a member of the triphenylmethane family of dyes and is known for its bright blue color. Uses: Acid blue 41 has several potential scientific research applications. one of the most promising uses is in the field of bioimaging. acid blue 41 has been shown to selectively stain mitochondria in live cells, making it a useful tool for studying mitochondrial function and dynamics. it has also been used as a fluorescent probe for detecting amyloid fibrils, which are associated with several neurodegenerative diseases. Additional or Alternative Names: LANAPERL BLUE B;CI 62130;ACID BLUE 41;ALIZARINE DIRECT BLUE ARA;ALIZARINE SAPPHIRE AR;10-dioxo-)-monosodiumsalt;10-dioxo-dihydro-monosodiumsalt;2-anthracenesulfonicacid,1-amino-9,10-dihydro-4-(p-(n-methylacetamido)anilino. Product Category: Acid Dyes. Appearance: Dark blue powder. CAS No. 2666-17-3. Molecular formula: C23H18N3NaO6S. Mole weight: 487.46. IUPACName: sodium;4-[4-[acetyl(methyl)amino]anilino]-1-amino-9,10-dioxoanthracene-2-sulfonate. Canonical SMILES: CC(=O)N(C)C1=CC=C(C=C1)NC2=CC(=C(C3=C2C(=O)C4=CC=CC=C4C3=O)N)S(=O)(=O)[O-].[Na+]. Density: 1.542 g/mL. ECNumber: 220-201-9. Product ID: ACM2666173. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Acid Blue 147. Alfa Chemistry.
Acid red 42 Acid Red 42 is a synthetic dye that belongs to the Acid Dye class. Acid Red 42, also known as C.I. Acid Red 42, Acid Red G, or Acid Scarlet 3R, is a specific dye within the Acid Dye category. Uses: Acid dyes are water-soluble anionic dyes commonly used for dyeing protein fibers such as silk, wool, and nylon, as well as other materials like leather and synthetic fibers. Additional or Alternative Names: Acid Red 42;2-Naphthalenesulfonic acid, 6-amino-4-hydroxy-5-2-(phenylsulfonyl)phenylazo-, monosodium salt;Acid red 42 (C.I. 17070);C.I. Acid Red 42;6-Amino-4-hydroxy-5-[. Product Category: Heterocyclic Organic Compound. Appearance: Powder. CAS No. 6245-60-9. Molecular formula: C22H16N3NaO6S2. Mole weight: 505.49. Purity: min. 98.0 area%. IUPACName: sodium;6-amino-5-[[2-(benzenesulfonyl)phenyl]diazenyl]-4-hydroxynaphthalene-2-sulfonate. Canonical SMILES: C1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2N=NC3=C(C=CC4=CC(=CC(=C43)O)S(=O)(=O)[O-])N.[Na+]. ECNumber: 228-359-0. Product ID: ACM6245609. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Acid red 27. Alfa Chemistry.
Adrenalone hydrochloride Adrenalone hydrochloride is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone hydrochloride is an inhibitor of dopamine β oxidase. Adrenalone hydrochloride is chemically similar to known norepinephrine transporter (NET) ligands with an IC 50 of 36.9 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 62-13-5. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B1308. MedChemExpress MCE
AFN-1252 AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is FASII Inhibitor which is potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 efficiently blocked daptomycin-induced phospholipid decoy production, even in the case of isolates resistant to AFN-1252, which prevented the inactivation of daptomycin and resulted in sustained bacterial killing. In turn, daptomycin prevented the fatty acid-dependent emergence of AFN-1252-resistant isolates in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AFN-1252; AFN 1252; AFN1252; API-1252; API1252; API 1252; AFN12520000; AFN 12520000; AFN12520000; Debio1452; Debio 1452; Debio1452. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 620175-39-5. Molecular formula: C22H21N3O3. Mole weight: 375.43. Purity: >98%. IUPACName: (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide. Canonical SMILES: O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)NC4=O. Product ID: ACM620175395. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Alizarin Complexone Alizarin-3-methyliminodiacetic acid is a colorimetric dye for the detection of fluoride ions, which is known to painters as Rose madder and Alizarin crimson. Alizarin Red is used in a biochemical assay to determine, quantitatively by colorimetry, the presence of calcific deposition by cells of an osteogenic lineage. It reacts with fluoride to form a lilac-blue complex which can be quantified colorimetrically at 620 nm to determine fluoride concentration. Synonyms: 2-[carboxymethyl-[(3,4-dihydroxy-9,10-dioxo-2-anthracenyl)methyl]amino]acetic acid; 2-[carboxymethyl-[(3,4-dihydroxy-9,10-dioxoanthracen-2-yl)methyl]amino]acetic acid. Grades: ≥ 95 %. CAS No. 3952-78-1. Molecular formula: C19H15NO8. Mole weight: 385.32. BOC Sciences 2
Apoptozole Apoptozole, also known as Apoptosis Activator VII, is an apoptosis-inducing small molecule that inhibits the ATPase activity of heat shock cognate 70 (Hsc70) and Hsp70 (Kd = 210 and 140 nM, respectively). Apoptozole dose-dependently induces apoptosis in cancer cells (IC50 = 5-7 μM). Synonyms: 4-((2-(3,5-bis(trifluoromethyl)phenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl)methyl)benzamide; Apoptozole; Apoptosis Activator VII. CAS No. 1054543-47-3. Molecular formula: C33H25F6N3O3. Mole weight: 625.57. BOC Sciences
Citric Acid, Anhydrous, ACS Citric acid is a weak organic acid that is known as a commodity chemical, as more than a million tonnes are produced every year by mycological fermentation on an industrial scale using crude sugar solutions, such as molasses and strains of Aspergillus niger. Citric acid is widely distributed in plants and in animal tissues and fluids and exist in greater than grace amounts in variety of fruits and vegetables, most notably in citrus fruits such as lemon and limes. Citric acid is mainly used as an acidifier, flavoring agent and chelating agent. Group: Biochemicals. Alternative Names: 2-Hydroxy-1,2,3-propanetricarboxylic Acid; 2-Hydroxy-1,2,3-propanetricarboxylic Acid; 2-Hydroxypropan-1,2,3-tricarboxylic Acid; 3-Carboxy-3-hydroxypentane-1,5-dioic Acid; Aciletten; Celenex 3P6; Cellborn SC-C; Chemfill; Citretten; Citric Acid Monoglyceride; Citro; E 330; EL 4; EL 4; F 0001; F 4020; FE 2; Grindsted Pro Tex TR 100; Hydrocerol A; INS 330; Jet Setter; Monoglyceride Citrate; NSC 112226; NSC 30279; NSC 626579; Suby G; Uro-trainer. Grades: ACS Grade. CAS No. 77-92-9. Pack Sizes: 500g, 1Kg, 2.5Kg, 5Kg. Molecular Formula: C6H8O7, Molecular Weight: 192.12. US Biological Life Sciences. USBiological 1
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Europium(III) acetate hydrate Europium(III) acetate hydrate. Uses: Europium(iII) acetate hydrate is used as a phosphor activator, color cathode-ray tubes and liquid-crystal displays used in computer monitors and televisions employ europium oxide as the red phosphor; no substitute is known. europium acetate is also applied in speciality glass for laser material. excitation of the europium atom by absorption of ultra violet radiation can result in specific energy level transitions within the atom creating an emission of visible radiation. Group: Solution deposition precursors. Alternative Names: Europium triacetate hydrate. CAS No. 62667-64-5. Product ID: Acetic acid; europium; hydrate. Molecular formula: 350.14. Mole weight: C6H14EuO7. CC(=O)O.CC(=O)O.CC(=O)O.O.[Eu]. InChI=1S/3C2H4O2.Eu.H2O/c3*1-2(3)4; /h3*1H3, (H, 3, 4); 1H2. RWVNKGWAXJFQSB-UHFFFAOYSA-N. 95%+. Alfa Chemistry Materials 3
Gastrodin Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H 2 O 2 -induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Gastrodine. CAS No. 62499-27-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0115. MedChemExpress MCE
GDC6036 GDC-6036, also known as RG6330, is an orally bioavailable, highly potent and selective KRAS G12C inhibitor, with a median IC50 in the sub-nanomolar range and greater than 18,000-fold selectivity for G12C versus non-G12C cell lines. GDC-6036 demonstrates greater potency and selectivity compared with other KRAS G12C inhibitors in vitro, and complete tumor growth inhibition in multiple KRAS G12C-positive cell lines and in xenograft mouse models. We will highlight the research program that led to the discovery and optimization of GDC-6036, which is currently in clinical development. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GDC-6036; GDC 6036; GDC6036; RG6330; RG-6330; RG 6330. Product Category: Inhibitors. Appearance: To be determined. CAS No. 2417987-45-0. Molecular formula: C29H32ClF4N7O2. Mole weight: 622.07. Purity: >98%. IUPACName: 1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one. Canonical SMILES: NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F. Product ID: ACM2417987450. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Divarasib. Alfa Chemistry.
Ibutamoren Mesylate Ibutamoren, also known as MK-677 or L-163,191, is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity. Synonyms: MK-677; MK 677; MK677; Crescendo; MK 0677; MK-0677; MK0677. Grades: >98%. CAS No. 159752-10-0. Molecular formula: C28H40N4O8S2. Mole weight: 624.77. BOC Sciences 9
Ipatasertib HCl Ipatasertib, also known as GDC-0068, is a highly selective pan-Akt inhibitor targeting Akt1/2/3 (IC50= 5 nM/18 nM/8 nM in cell-free assays) with 620-fold selectivity over PKA. Ipatasertib is advancing in clinical development including a Phase 3 trial in patients with prostate cancer and three Phase 2 trials in patients with breast cancer, gastric cancer and prostate cancer. Synonyms: (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one hydrochloride.; GDC0068; GDC-0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib; Ipatasertib hydrochloride, Ipatasertib HCl. CAS No. 1489263-16-2. Molecular formula: C24H33Cl2N5O2. Mole weight: 494.46. BOC Sciences 10
JNJ-10198409 JNJ-10198409, also known as RWJ-540973, is an inhibitor of PDGF-BB tyrosine kinase with an IC50 value of 4.2 nM. JNJ-10198409 is a competitive antagonist of the ATP binding and hydrolysis at this receptor, resulting in a dose dependent inhibition of tumor growth and angiogenesis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: JNJ-10198409; JNJ 10198409; JNJ10198409; RWJ-540973; RWJ 540973; RWJ540973. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 627518-40-5. Molecular formula: C18H16FN3O2. Mole weight: 325.34. Purity: >98%. IUPACName: N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-indeno[1,2-c]pyrazol-3-amine. Canonical SMILES: COC1=CC2=C(C=C1OC)CC3=C2NN=C3NC4=CC=CC(F)=C4. Product ID: ACM627518405-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Methyl 2-acetamido-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-glucopyranoside Methyl 2-acetamido-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-glucopyranoside, known for its multifaceted applications in the research of an array of afflictions such as cancer, diabetes and bacterial infections. Synonyms: [(2R,3S,4S,5R,6R)-6-[(2R,3S,4R,5R,6S)-5-acetamido-3-hydroxy-2-(hydroxymethyl)-6-methoxyoxan-4-yl]oxy-3,4,5-triacetyloxyoxan-2-yl]methyl acetate; Methyl 2-Acetamido-2-deoxy-O-[ss-D-(2,3,4,6-tetraacetyl) galactopyranosyl]-alpha-D-glucopyranoside; Methyl 2-Acetamido-2-deoxy-O-[ss-D-(2,3,4,6-tetraacetyl) galactopyranosyl]-?-D-glucopyranoside. CAS No. 62998-28-1. Molecular formula: C23H35NO15. Mole weight: 565.52. BOC Sciences 12
Mordant yellow 26 Mordant Yellow 26, also known as Acid Yellow 26 or C.I. 13065, is a synthetic dye that belongs to the class of acid dyes. Uses: Mordant yellow 26 is commonly used in the textile and dyeing industries for coloring various materials, including wool, silk, and nylon. Additional or Alternative Names: tetrasodium 5,5'-[(2,2'-disulphonato[1,1'-biphenyl]-4,4'-diyl)bis(azo)]disalicylate;Acid mordant Yellow 26;Benzoic acid, 3,3-(2,2-disulfo1,1-biphenyl-4,4-diyl)bis(azo)bis6-hydroxy-, tetrasodium salt;MORDANT YELLOW 26;3,3'-(2,2'-Disulfobiphenyl-4,4'-diyl. Product Category: Heterocyclic Organic Compound. Appearance: Dark yellow. CAS No. 6232-49-1. Molecular formula: C26H14N4Na4O12S2. Mole weight: 730.5. Purity: 0.95. Canonical SMILES: C1=CC(=C(C=C1N=NC2=CC(=C(C=C2)[O-])C(=O)O)S(=O)(=O)[O-])C3=C(C=C(C=C3)N=NC4=CC(=C(C=C4)[O-])C(=O)O)S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]. ECNumber: 228-336-5. Product ID: ACM6232491. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Oxalic Acid An impurity of oxaliplatin which is a coordination complex that is used in cancer chemotherapy. A reducing agent and its conjugate base, known as oxalate (C2O42?), is a useful chelating agent for metal cations. Group: Biochemicals. Alternative Names: Ethanedioic Acid; Aktisal; Aquisal; DeerClean; NSC 132055; NSC 151956; NSC 62774; NSC 76990; Ultraplast Activate S 52. Grades: Highly Purified. CAS No. 144-62-7. Pack Sizes: 2.5g. US Biological Life Sciences. USBiological 2
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Oxalic Acid-(1,2-13C2) Oxalic Acid-(1,2-13C2) is the labelled analog of Oxalic Acid (O845120) which is an impurity of oxaliplatin which is a coordination complex that is used in cancer chemotherapy. It is also a reducing agent and its conjugate base, known as oxalate (C2O42?), is a useful chelating agent for metal cations. Group: Biochemicals. Grades: Highly Purified. CAS No. 62654-02-8. Pack Sizes: 5mg, 10mg. Molecular Formula: 13C2H2O4. US Biological Life Sciences. USBiological 2
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Oxytocin acetate Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: α-Hypophamine acetate; Oxytocic hormone acetate. CAS No. 6233-83-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17571A. MedChemExpress MCE
Relugolix Relugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH) receptor antagonist administered orally. By preventing LH-RH from binding with the LH-RH receptor in the anterior pituitary gland and suppressing the secretion of luteinizing hormone (LH) and follicle stimulation hormone (FSH) from the anterior pituitary gland, TAK-385 controls the effect of LH and FSH on the ovary, reduces the level of estrogen in blood, which is known to be associated with the development of endometriosis and uterine fibroids, and is expected to improve the symptoms of these disorders. Uses: Androgen antagonists. Synonyms: TAK-385; N-[4-[1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-1,2,3,4-tetrahydro-3-(6-methoxy-3-pyridazinyl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-N'-methoxyurea; Orgovyx; RVT 601; 1-{4-[1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea. Grades: ≥95%. CAS No. 737789-87-6. Molecular formula: C29H27F2N7O5S. Mole weight: 623.63. BOC Sciences 9
[(R,R)-Teth-TsDpen RuCl] [(R,R)-Teth-TsDpen RuCl]. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1192620-83-9;MFCD16294993;{N-[3-(eta6-Phenyl)propyl]-[(1R-2R)-1,2-diphenyl-1-4-methylbenzenesulfonylamidato(kN')-ethyl-2-amino-(kN)]}ruthenium(II). Product Category: Ruthenium series catalysts. CAS No. 1192620-83-9. Molecular formula: C30H31ClN2O2RuS. Mole weight: 620.17g/mol. IUPACName: chlororuthenium(1+);[(1R,2R)-1,2-diphenyl-2-(3-phenylpropylamino)ethyl]-(4-methylphenyl)sulfonylazanide. Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)[N-]C(C2=CC=CC=C2)C(C3=CC=CC=C3)NCCCC4=CC=CC=C4.Cl[Ru+]. Product ID: ACM1192620839. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
Selumetinib Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells. MEK 1 and 2 are dual-specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various tumor cell types, and are drivers of diverse cellular activities, including cellular proliferation. Check for active clinical trials or closed clinical trials using this agent. Synonyms: ARRY-142886; ARRY 142886; ARRY142886; AZD6244; AZD-6244; AZD 6244; ARRY-886; ARRY886; ARRY 886. Grades: >98%. CAS No. 606143-52-6. Molecular formula: C17H15BrClFN4O3. Mole weight: 457.684. BOC Sciences 8
SKF-38393 hydrochloride SKF-38393, aslo known as (+/-)-SKF-38393, is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist. It has stimulant and anorectic effects. Synonyms: SKF-38393; SKF 38393; SKF38393; SKF-38,393; SKF 38,393; SKF38,393; SKF-38393 HCl; SKF-38393 hydrochloride. Grades: 98%. CAS No. 62717-42-4. Molecular formula: C16H18ClNO2. Mole weight: 291.78. BOC Sciences 10
Tasidotin hydrochloride Tasidotin, also know as ILX-651, is an orally active synthetic microtubule-targeted derivative of the marine depsipeptide dolastatin-15, is currently undergoing clinical evaluation for cancer treatment. Tasidotin inhibited proliferation of MCF7/GFP breast cancer cells with an IC(50) of 63 nmol/L and inhibited mitosis with an IC(50) of 72 nmol/L in the absence of detectable effects on spindle microtubule polymer mass. Tasidotin inhibited the polymerization of purified tubulin into microtubules weakly (IC(50) approximately 30 micromol/L). However, it strongly suppressed the dynamic instability behavior of the microtubules at their plus ends at concentrations approximately 5 to 10 times below those required to inhibit polymerization. Synonyms: ILX 651; ILX651; ILX-651. CAS No. 623174-20-9. Molecular formula: C32H59ClN6O5. Mole weight: 643.31. BOC Sciences 11
Tradipitant Tradipitant, also known as VLY-686 and LY686017, is the 2nd generation neurokinin-1 receptor antagonist, which showed activity in preclinical anxiety models. LY686017 may be a possible therapy for alcoholism. LY686017 can be also served as a suitable chemical platform for future imaging ligand development. (last update: ). Synonyms: LY686017; LY 686017; LY-686017; VLY 686; VLY686; VLY-686. Grades: 99%. CAS No. 622370-35-8. Molecular formula: C28H16ClF6N5O. Mole weight: 587.91. BOC Sciences 11
Xanthosine-5'-Triphosphate Xanthosine-5'-Triphosphate, known as XTP, holds immense significance within the biomedical sector. It serves as an essential building block for RNA and DNA synthesis, thereby playing a pivotal role in genetic material generation. Its versatility extends to governing crucial cellular operations like protein synthesis, signaling pathways, and enzymatic reactions. Synonyms: Xanthosine-TP. Grades: ≥ 95 % by HPLC. CAS No. 6253-56-1. Molecular formula: C10H15N4O15P3(free acid). Mole weight: 524.16 (free acid). BOC Sciences

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