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L-(+)-Ergothioneine (ET) is a sulfur-containing amino acid, which is only produced by Actinomycetales bacteria and non-yeast like fungi belonging to the division Basidiomycota and Ascomycota. It was originally isolated from Claviceps purpurea or rye ergot. It is obtained from L-histidine, which is converted into betaine form called hercynine. It is found in both animals and plants, and mammals usually obtain it from their diet, e.g. through mushrooms or oats. It is tautomeric in nature, and in neutral aqueous solution exists in thione form. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-Ergothioneine; (+)-Ergothioneine; Thiasine; Sympectothion; Ergothionine; Erythrothioneine; Thiolhistidinebetaine. Product Category: Heterocyclic Organic Compound. Appearance: Colorless liquid. CAS No. 497-30-3. Molecular formula: C9H15N3O2S. Mole weight: 229.3. ECNumber: 207-843-5. Product ID: ACM497303. Alfa Chemistry ISO 9001:2015 Certified.
L-(+)-Ergothioneine
L-Ergothioneine is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Group: Biochemicals. Alternative Names: (αS)-α-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium Inner Salt; 2-Mercaptohistidine Betaine; NSC 7175; 2-Mercapto-N,N-dimethylhistidine Methyl Ester Betaine; 2-Mercapto-histidine; Sympectothion; Thiasine; Thioneine; Thiotane. Grades: Highly Purified. CAS No. 497-30-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C?H??N?O?S, Molecular Weight: 229.3. US Biological Life Sciences.
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L-(+)-Ergothioneine-d9
Labeled L-Ergothionine. It is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Group: Biochemicals. Alternative Names: (αS)-α-Carboxy-2,3-dihydro-N,N,N-tri(methyl-d3)-2-thioxo-1H-imidazole-4-ethanaminium Inner Salt; 2-Mercaptohistidine Betaine-d9; NSC 7175-d9; 2-Mercapto-N,N-dimethylhistidine Methyl Ester Betaine-d9; 2-Mercapto-histidine-d9; Sympectothion-d9; Thiasine-d9; Thioneine-d9; Thiotane-d9. Grades: Highly Purified. CAS No. 497-30-3-unlabeled. Pack Sizes: 1mg. Molecular Formula: C?H?D?N?O?S, Molecular Weight: 238.35. US Biological Life Sciences.
Worldwide
N-Desmethyl L-Ergothioneine-d6 Methyl Ester
Intermediate in the production of labeled L-Ergothioneine. Group: Biochemicals. Alternative Names: (S)-α-(Dimethylamino)-2,3-dihydro-2-thioxo-1H-imidazole-4-propanoic-d6 Acid Methyl Ester; N,N-Dimethyl-2-mercapto-L-histidine-d6 Methyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
N-Desmethyl L-ergothioneine methyl ester
N-Desmethyl L-ergothioneine methyl ester. Group: Biochemicals. Alternative Names: (S)-a-(Dimethylamino)-2,3-dihydro-2-thioxo-1H-imidazole-4-propanoic acid methyl ester; N,N-Dimethyl-2-mercapto-L-histidine methyl ester. Grades: Highly Purified. CAS No. 162138-71-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C9H15N3O2S. US Biological Life Sciences.
Intermediate in the production of labeled L-Ergothioneine. Group: Biochemicals. Alternative Names: 1-(Ethoxycarbonyl)-2-[(ethoxycarbonyl)thio]-N,N-dimethyl-L-histidine-d6 Methyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Intermediate in the production of L-Ergothioneine. Group: Biochemicals. Grades: Highly Purified. CAS No. 162138-72-9. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
2-Mercapto-L-histidine
. Uses: An intermediate in the formation of l-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. in humans, l-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cata. Synonyms: L-His(2-mercapto)-OH. Grades: ≥ 98% (TLC). CAS No. 2002-22-4. Molecular formula: C6H9N3O2S. Mole weight: 187.20.
An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal f. Group: Biochemicals. Alternative Names: 2-Thiolhistidine, 1H-Imidazole-4-propanoic Acid. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
2-Mercaptoglyoxalines derivative used in the preparation of L-(+)-Ergothioneine. Group: Biochemicals. Alternative Names: 2-Thiocarbonic Acid Ethyl Ester L-Histidine Dihydrochloride; Thiolcarbonic Acid O-Ethyl Ester 2-Mercaptohistidine Dihydrochloride. Grades: Highly Purified. CAS No. 909272-14-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ergothioneine
Ergothioneine is an imidazole-2-thione derivative with orally active histidine betaine. Ergothioneine is a specific inhibitor of p38-MAPK and Akt , which plays a protective role in cell apoptosis induced by stress. Ergothioneine has antioxidant activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: L-(+)-Ergothioneine. CAS No. 497-30-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1914.
L-Hercynine is a precursor of L-(+)-Ergothioneine (E600000); a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Group: Biochemicals. Grades: Highly Purified. CAS No. 534-30-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H15N3O2. US Biological Life Sciences.
Worldwide
L-Histidine methyl ester dihydrochloride
Used in the preparation of optically pure L-(+)-Ergothioneine. Synonyms: L-His-OMe 2HCl; H-L-His-OMe dihydrochloride; L-Histidine Methyl Ester 2HCl; H-His-OMe dihydrochloride; HISTIDINE-OME 2 HCl; H-His-Ome 2HCI. Grades: ≥ 99% (HPLC). CAS No. 7389-87-9. Molecular formula: C7H11N3O2·2HCl. Mole weight: 242.10.
L-Histidine Methyl Ester Dihydrochloride
Used in the preparation of optically pure L-(+)-Ergothioneine. Group: Biochemicals. Grades: Highly Purified. CAS No. 7389-87-9. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C?H??Cl?N?O?. US Biological Life Sciences.
Worldwide
N2,N5-Dibenzoyl-4-oxo-L-ornithine Methyl Ester
N2,N5-Dibenzoyl-4-oxo-L-ornithine Methyl Ester is an intermediate in the preparation of L-(+)-Ergothioneine (E600000). Group: Biochemicals. Alternative Names: 2,5-Di(benzoylamino)-4-oxo-pentanoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 78420-25-4. Pack Sizes: 50mg. US Biological Life Sciences.
Used in the preparation of optically pure labeled L-(+)-Ergothioneine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
An intermediate in the preparation of L-(+)-Ergothioneine (E600000). Group: Biochemicals. Grades: Highly Purified. CAS No. 78420-23-2. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
γ-glutamyl hercynylcysteine S-oxide hydrolase
The enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria. Group: Enzymes. Synonyms: EgtC. Enzyme Commission Number: EC 3.5.1.118. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4398; γ-glutamyl hercynylcysteine S-oxide hydrolase; EC 3.5.1.118; EgtC. Cat No: EXWM-4398.
γ-glutamyl hercynylcysteine S-oxide synthase
Requires Fe2+ for activity. The enzyme, found in bacteria, is specific for both hercynine and γ-L-glutamyl-L-cysteine. It is part of the biosynthesis pathway of ergothioneine. Group: Enzymes. Synonyms: EgtB. Enzyme Commission Number: EC 1.14.99.50. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1060; γ-glutamyl hercynylcysteine S-oxide synthase; EC 1.14.99.50; EgtB. Cat No: EXWM-1060.
hercynylcysteine S-oxide synthase
Requires Fe2+ for activity. The enzyme, found in fungal species, is part of a fusion protein that also has the the activity of EC 2.1.1.44, L-histidine Nα-methyltransferase. It is part of the biosynthesis pathway of ergothioneine. The enzyme can also use L-selenocysteine to produce hercynylselenocysteine, which can be converted to selenoneine. Group: Enzymes. Synonyms: Egt1; Egt-1. Enzyme Commission Number: EC 1.14.99.51. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1061; hercynylcysteine S-oxide synthase; EC 1.14.99.51; Egt1; Egt-1. Cat No: EXWM-1061.
L-histidine Nα-methyltransferase
Part of the biosynthetic pathway of ergothioneine. Group: Enzymes. Synonyms: dimethylhistidine N-methyltransferase; dimethylhistidine methyltransferase; histidine-α-N-methyltransferase; S-adenosyl-L-methionine:α-N,α-N-dimethyl-L-histidine α-N-methyltransferase; S-adenosyl-L-methionine:Nα,Nα-dimethyl-L-histidine Nα-methyltransferase. Enzyme Commission Number: EC 2.1.1.44. CAS No. 62213-53-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1948; L-histidine Nα-methyltransferase; EC 2.1.1.44; 62213-53-0; dimethylhistidine N-methyltransferase; dimethylhistidine methyltransferase; histidine-α-N-methyltransferase; S-adenosyl-L-methionine:α-N,α-N-dimethyl-L-histidine α-N-methyltransferase; S-adenosyl-L-methionine:Nα,Nα-dimethyl-L-histidine Nα-methyltransferase. Cat No: EXWM-1948.
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