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L-Serinamide Synonyms: Serinamide. CAS No. 6791-49-7. Molecular formula: C3H8N2O2. Mole weight: 104.1. BOC Sciences 6
Exenatide Exenatide, naturally occured in the saliva of the Gila monster, an incretin mimetic that has glucoregulatory effect. As a glucagon-like peptide-1 (GLP-1) receptor agonist, it stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways. Uses: Hypoglycemic agents. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide; Exendin 3 (Heloderma horridum), 2-glycine-3-L-glutamic acid-; Exendin 4 (Heloderma suspectum); AC 2993; AC 2993A; AC 2993LAR; Bydureon; Byetta; DA 3091; EQW; Exatenide; Exenatide LAR; Exendin 4; Exendin-4; ITCA 650; LAEx4; H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. CAS No. 141758-74-9. Molecular formula: C184H282N50O60S. Mole weight: 4186.56. BOC Sciences 3
Exenatide acetate Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-, acetate (1:x); Exendin 4 (Heloderma suspectum), acetate; Exendin-4 acetate; H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2.CH3CO2H. Grades: >98%. CAS No. 914454-01-6. Molecular formula: C184H282N50O60S.C2H4O2. Mole weight: 4246.61. BOC Sciences 9
LEP (116-130) (mouse) TFA LEP (116-130) (mouse) TFA is a synthetic leptin peptide fragment. Synonyms: Leptin Fragment 116-130 Amide mouse TFA; LEP(116-130) (mouse) TFA; H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2.TFA; L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-seryl-glycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-serinamide trifluoroacetic acid; L-Serinamide, L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-serylglycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-α-glutamyl-, 2,2,2-trifluoroacetate (1:1). Grades: ≥95%. CAS No. 2828433-16-3. Molecular formula: C66H110F3N19O26S. Mole weight: 1674.77. BOC Sciences 6
L-Serine amide hydrochloride Synonyms: L-Ser-NH2 HCl; L-β-Hydroxyalanine amide hydrochloride; L-Ser-NH2 HCl; L-Serinamide hydrochloride; SERINE-NH2 HCl; Ser-NH2 HCl; serine amide hydrochloride. Grades: ≥ 98% (NMR). CAS No. 65414-74-6. Molecular formula: C3H8N2O2·HCl. Mole weight: 140.57. BOC Sciences 5
Oprozomib Oprozomib is the second class of proteasome inhibitors with higher specificities and reduced toxicities, against head and neck squamous cell carcinoma. Group: Biochemicals. Alternative Names: ONX 0912; PR 047; O-Methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-serinamide. Grades: Highly Purified. CAS No. 935888-69-0. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 3
Worldwide
tert-Butyln-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[4-(hydrazinecarbonyl)phenyl]-3-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2- Heterocyclic Organic Compound. Alternative Names: 125598-87-0, N-(tert-butoxycarbonyl)-L-tryptophyl-L-leucyl-N-{(2S)-1-[4-(hydrazinylcarbonyl)phenyl]-3-oxopropan-2-yl}-L-serinamide. CAS No. 125598-87-0. Molecular formula: C35H47N7O8. Mole weight: 693.79 g/mol. Purity: 0.96. IUPACName: tert-butyl N-[1-[[1-[[1-[[1-[4- (hydrazinecarbonyl)phenyl]-3-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3- (1H-indol-3-yl)-1-oxopropan-2-yl]carbamate. Canonical SMILES: CC (C)CC (C (=O)NC (CO)C (=O)NC (CC1=CC=C (C=C1)C (=O)NN)C=O)NC (=O)C (CC2=CNC3=CC=CC=C32)NC (=O)OC (C) (C)C. Density: 1.268g/cm³. Catalog: ACM125598870. Alfa Chemistry. 4

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