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100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C12H9F3N2O2. CAS No. 75706-12-6. Prepack ID 77117657-100mg. Molecular Weight 270.21. See USA prepack pricing.
Leflunomide
Leflunomide. Group: Biochemicals. Grades: Purified. CAS No. 75706-12-6. Pack Sizes: 50mg. US Biological Life Sciences.
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Leflunomide
Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent. Uses: Scientific research. Group: Natural products. Alternative Names: HWA486; RS-34821; SU101. CAS No. 75706-12-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0083.
Leflunomide 3-isomer
Leflunomide 3-isomer. Group: Biochemicals. Alternative Names: 5-Methyl-N-[3- (trifluoromethyl) phenyl]-4-isoxazolecarboxamide; Leflunomide imp. E (EP). Grades: Highly Purified. CAS No. 61643-23-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C12H9F3N2O2. US Biological Life Sciences.
An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Group: Biochemicals. Alternative Names: 5- methyl isoxazole-4- [4-trifluoro methyl carboxanilide] -d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Leflunomide-d4(phenyl-d4)
Heterocyclic Organic Compound. CAS No. 1189987-23-2. Molecular formula: 274.23. Purity: 98 atom % D. Catalog: ACM1189987232.
Leflunomide EP impurity A
Leflunomide EP impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 455-14-1. Molecular Formula: C7H6F3N. Mole Weight: 161.13. Catalog: APB455141.
Leflunomide EP impurity H
Leflunomide EP impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 24522-30-3. Molecular Formula: C10H7F3N2O. Mole Weight: 228.17. Catalog: APB24522303.
Leflunomide impurity 1
Leflunomide impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 61643-23-0. Molecular Formula: C12H9F3N2O2. Mole Weight: 270.21. Catalog: APB61643230.
Leflunomide Impurity C
Leflunomide analogue, with potential antiinflammatory and anti-viral activity. Synonyms: 3-Methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide; Leflunomide 3-Isomer. Grades: > 95%. CAS No. 61643-23-0. Molecular formula: C12H9F3N2O2. Mole weight: 270.21.
Leflunomide Impurity D
An intermediate for synthesis of Leflunomide. Synonyms: 5-Methylisoxazole-4-carboxylic Acid. Grades: > 95%. CAS No. 42831-50-5. Molecular formula: C5H5NO3. Mole weight: 127.10.
5-Desmethyl-3-methyl leflunomide. Group: Biochemicals. Alternative Names: 3-Methyl-N-[4- (trifluoromethyl) phenyl]-4-isoxazolecarboxamide; N-[4- (Trifluoromethyl) phenyl]-3-methylisoxazole-4-carboxamide. Grades: Highly Purified. CAS No. 208401-20-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H9F3N2O2. US Biological Life Sciences.
Worldwide
2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide
2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide is an impurity of Teriflunomide (A771726) which is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1385789-70-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H12N2O2, Molecular Weight: 216.24. US Biological Life Sciences.
2-Cyano-N-[3-methyl-4- (trifluoromethyl) phenyl]-acetamide is used to synhesize analogues of leflunomide active metabolite with antiarthritic potential. Group: Biochemicals. Grades: Highly Purified. CAS No. 179637-55-9. Pack Sizes: 500mg, 5g. Molecular Formula: C11H9F3N2O, Molecular Weight: 242.2. US Biological Life Sciences.
Worldwide
2-Cyano-N-[4- (trifluoromethyl) phenyl]acetamide
2-Cyano-N-[4- (trifluoromethyl) phenyl]acetamide (Leflunomide EP Impurity H) is used to prepare aminothiophene carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. It is also used to synthesize (1,2,3-triazol-4-yl)benzenamines as inhibitors against VEGF receptors 1 and 2. Group: Biochemicals. Grades: Highly Purified. CAS No. 24522-30-3. Pack Sizes: 1g, 10g. Molecular Formula: C10H7F3N2O. US Biological Life Sciences.
(2Z)-2-Cyano-N-(4-cyanophenyl)-3-hydroxy-2-Butenamide was used in the study of structural requirements for bioactive mtabolites of leflunomide. Group: Biochemicals. Grades: Highly Purified. CAS No. 202057-74-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C12H9N3O2, Molecular Weight: 227.22. US Biological Life Sciences.
Worldwide
5-Methylisoxazole-3-carboxylic-d4 Acid
A labelled metabolite of UTL-5b, a structural analog of the anti-arthritic drug, Leflunomide (L322750). Group: Biochemicals. Alternative Names: 5-(Methyl-d3)-3-isoxazole-4-d-carboxylic Acid; 3-Carboxy-5-methylisoxazole-d4; 5-Methyl-3-isoxazolecarboxylic-d4 Acid. Grades: Highly Purified. CAS No. 1267623-84-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
5-Methylisoxazole-4-carboxylic Acid
An intermediate for synthesis of Leflunomide. Herbicidal activities towards Digitaria ciliaris. Group: Biochemicals. Alternative Names: 5-Methyl-4-isoxazolecarboxylic Acid. Grades: Highly Purified. CAS No. 42831-50-5. Pack Sizes: 250mg. US Biological Life Sciences.
The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. Group: Biochemicals. Alternative Names: N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide-d4, 2-Cyano-3-hydroxy-N-[4- (trifluoromethyl) phenyl]-2-beuteamide-d4, LEF-M-d4. Grades: Highly Purified. CAS No. 1185240-22-5. Pack Sizes: 1mg. US Biological Life Sciences.
The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. Group: Biochemicals. Alternative Names: N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4- (trifluoromethyl) phenyl]-2-beuteamide, LEF-M. Grades: Highly Purified. CAS No. 163451-81-8. Pack Sizes: 10mg. US Biological Life Sciences.
Physiologically active metabolite of the immunosuppressive drug leflunomide. Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kB activation in a dose- and time-dependent manner. Also inhibits the activity of COX-2 in vitro and in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ethyl 3-methylisoxazole-4-carboxylate
an impurity in Leflunomide. Synonyms: 3-Methylisoxazole-4-carboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 20328-15-8. Molecular formula: C7H9NO3. Mole weight: 155.15.
PfDHODH-IN-1
PfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183945-55-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135648.
Teriflunomide
Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A77 1726. CAS No. 163451-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15405.
Teriflunomide-E Isomer
the active metabolite of Leflunomide. Synonyms: 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide. Grades: > 95%. CAS No. 214782-56-6. Molecular formula: C12H9F3N2O2. Mole weight: 270.21.
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