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| Product | Description | |
|---|---|---|
| Leukotriene B4 | ~100 ?g/mL in ethanol, ?97%. Group: Fluorescence/luminescence spectroscopy. |  |
| Leukotriene B4 | Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LTB4; 5(S),12(R)-DiHETE. CAS No. 71160-24-2. Pack Sizes: 25 μg (297.2 μM * 250 μL in Ethanol). Product ID: HY-107608. |  |
| Leukotriene B4-3-aminopropylamide | Leukotriene B4-3-aminopropylamide is a LTB4 analog that exhibits high binding affinity for BLT1 receptor. Synonyms: LTB4-3-aminopropylamide; (5S,6Z,8E,10E,12R,14Z)-N-(3-aminopropyl)-5,12-dihydroxyicosa-6,8,10,14-tetraenamide. Grades: ≥95%. CAS No. 89596-43-0. Molecular formula: C23H40N2O3. Mole weight: 392.6. |  |
| Leukotriene B4 dimethyl amide | Leukotriene B4 dimethyl amide is a lipid mediator and Leukotriene B4 antagonist. It was shown to inhibit neutrophil degranulation induced by LTB4. Synonyms: LTB4 dimethyl amide; N,N-dimethyl-5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraen-1-amide. Grades: ≥97%. CAS No. 83024-92-4. Molecular formula: C22H37NO3. Mole weight: 363.5. | |
| Leukotriene B4 ethanolamide | Leukotriene B4 ethanolamide is a potent antagonist of leukotriene B4 receptor with 3-fold higher affinity than leukotriene B4. It exhibits anti-inflammatory activity. Synonyms: LTB4-EA; (5S,12R)-5,12-Dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide. Grades: ≥97%. CAS No. 877459-63-7. Molecular formula: C22H37NO4. Mole weight: 379.5. | |
| 12-epi Leukotriene B4 | 12-epi Leukotriene B4 is a leukotriene with less affinity than LTB4 at LTB4 receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 83709-73-3. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences. |  Worldwide |
| 12-Epi leukotriene B4 | 12-Epi leukotriene B4 is a leukotriene with less affinity than LTB4 at LTB4 receptors. Synonyms: 12-epi LTB4; 5S,12S-dihydroxy-6E,8Z,10E,14Z-eicosatetraenoic acid. Grades: ≥97%. CAS No. 83709-73-3. Molecular formula: C20H32O4. Mole weight: 336.5. | |
| 12-Oxoleukotriene B4 in acetonitrile | 12-oxo Leukotriene B4 in acetonitrile is a potent eicosanoid lipid mediators. Group: Biochemicals. Grades: Highly Purified. CAS No. 136696-10-1. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H30O4, Molecular Weight: 334.45. US Biological Life Sciences. | Worldwide |
| 14,15-dehydro Leukotriene B4 | 14,15-dehydro Leukotriene B4 is an LTB4 receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 114616-11-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences. | Worldwide |
| 14,15-Dehydro leukotriene B4 | 14,15-Dehydro leukotriene B4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. Synonyms: 14,15-dehydro LTB4; 5S,12R-dihydroxy-6Z,8E,10E-eicosatrien-14-ynoic acid. Grades: ≥97%. CAS No. 114616-11-4. Molecular formula: C20H30O4. Mole weight: 334.5. | |
| 18-carboxy dinor Leukotriene B4 | 18-carboxy dinor Leukotriene B4 is b-oxidation metabolite of LTB4. Group: Biochemicals. Grades: Highly Purified. CAS No. 102674-12-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C18H26O6, Molecular Weight: 338.4. US Biological Life Sciences. | Worldwide |
| 20-Carboxy-leukotriene B4 | ~1 mg/mL in ethanol, ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| 20-Carboxy-Leukotriene B4 | 20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4 (LTB4; HY-107608). 20-Carboxy-Leukotriene B4 binds to the BLT1 receptor with high affinity. 20-Carboxy-Leukotriene B4 inhibits LTB4-mediated neutrophil responses (migration, degranulation, leukotriene biosynthesis) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 20-COOH LTB4. CAS No. 80434-82-8. Pack Sizes: 25 μg (272.89 μM * 250 μL in Ethanol). Product ID: HY-113483. | |
| 20-trifluoro Leukotriene B4 | 20-trifluoro Leukotriene B4 is an eicosanoid lipid mediator. Group: Biochemicals. Grades: Highly Purified. CAS No. 115178-97-7. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H29F3O4, Molecular Weight: 390.44. US Biological Life Sciences. | Worldwide |
| Anti-Leukotriene B4 Receptor BLT1 antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Leukotriene B4 Receptor BLT2 antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| leukotriene-B4 20-monooxygenase | A heme-thiolate protein (P-450). Not identical with EC 1.14.13.34, leukotriene-E4 20-monooxygenase. Group: Enzymes. Synonyms: leukotriene-B4 20-hydroxylase; leucotriene-B4 ω-hydroxylase; LTB4 20-hydroxylase; LTB4 ω-hydroxylase. Enzyme Commission Number: EC 1.14.13.30. CAS No. 90119-11-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0837; leukotriene-B4 20-monooxygenase; EC 1.14.13.30; 90119-11-2; leukotriene-B4 20-hydroxylase; leucotriene-B4 ω-hydroxylase; LTB4 20-hydroxylase; LTB4 ω-hydroxylase. Cat No: EXWM-0837. |  |
| 20-COOH-LTB4 | 20-COOH-LTB4 is a leukotriene B4 metabolite and substrate for β-oxidation pathways. Group: Biochemicals. Grades: Highly Purified. CAS No. 80434-82-8. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H30O6, Molecular Weight: 366.45. US Biological Life Sciences. | Worldwide |
| 2- (2-Formyl-6-methoxyphenoxy) propanoic Acid | 2- (2-Formyl-6-methoxyphenoxy) propanoic Acid has been used as a reactant for the preparation of leukotriene B4 antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 590395-57-6. Pack Sizes: 1g, 10g. Molecular Formula: C11H12O5, Molecular Weight: 224.21. US Biological Life Sciences. | Worldwide |
| 4-O-Demethylbarbatic acid | 4-O-Demethylbarbatic acid is an inhibitor of leukotriene B4 (LTB4). Synonyms: β-Resorcylic acid, 3,6-dimethyl-, 4-(3,6-dimethyl-β-resorcylate) (8CI); 4-Carboxy-3-hydroxy-2,5-dimethylphenyl 2,4-dihydroxy-3,6-dimethylbenzoate; Barbatic acid, 4-O-demethyl-. CAS No. 20372-89-8. Molecular formula: C18H18O7. Mole weight: 346.33. | |
| 5s-12r-Dihydroxy-6z,8e,10e,14z-eicosatetraenoic-6,7,14,15-d4 acid | 5s-12r-Dihydroxy-6z,8e,10e,14z-eicosatetraenoic-6,7,14,15-d4 acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5S-12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC-6,7,14,15-D4 ACID;LEUKOTRIENE B4-D4. Product Category: Heterocyclic Organic Compound. Appearance: A solution in acetonitrile. CAS No. 124629-74-9. Molecular formula: C20H28D4O4. Mole weight: 340.49. Product ID: ACM124629749. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Acebilustat | Acebilustat, formerly known as ZK322, is an oral anti-inflammatory designed to reduce the production of leukotriene B4 (LTB4). Synonyms: 4-(((1S,4S)-5-(4-(4-(oxazol-2-yl)phenoxy)benzyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)methyl)benzoic acid; ZK322; ZK-322; ZK 322; CTX-4430; EP-501; CTX4430; EP501; CTX 4430; EP 501; Acebilustat, CAS#943764-99-6. CAS No. 943764-99-6. Molecular formula: C29H27N3O4. Mole weight: 481.55. | |
| Atreleuton | Atreleuton, a kind of urea compound, has been found to be a 5-lipoxygenase inhibitor as well as Leukotriene B4 receptor antagonist that could probably be useful in study of sorts of diseases like asthma and acute coronary syndromes. It has already been discontinued by VIA Pharmaceuticals. Uses: Lipoxygenase inhibitors. Synonyms: Atreleuton; ABT-761; ABT 761; VIA 2291; VIA-2291; VIA2291; A-85761; Abbott-85761; Atreleuton [USAN]; UNII-U301T88E1M; ABT 761; 1-[(2R)-4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxyurea. Grades: 98%. CAS No. 154355-76-7. Molecular formula: C16H15FN2O2S. Mole weight: 318.37. | |
| CAY10583 | Leukotriene B4 (LTB4) is a leukotriene involved in inflammation. It is produced from leukocytes in response to inflammatory mediators and is able to induce the adhesion and activation of leukocytes on the endothelium, allowing them to bind to and cross it into the tissue. CAY10583 is a selective and synthetic LTB4 agonist with EC50 of 20 nM. Synonyms: CAY 10583; CAY-10583. Grades: ≥98%. CAS No. 862891-27-8. Molecular formula: C25H25NO3. Mole weight: 387.5. | |
| CP-105696 | CP-105696, a chromen derivative, has been found to be a leukotriene B4 receptor antagonist that was once studied against sorts of nflammatory disease. Uses: Leukotriene antagonists. Synonyms: CP-105696; UNII-Z7354TW4BM; CP-105,696; CHEMBL51770; CP 105696; Z7354TW4BM; 1-[(3S,4R)-4-hydroxy-3-[(4-phenylphenyl)methyl]-3,4-dihydro-2H-chromen-7-yl]cyclopentane-1-carboxylic acid. Grades: 98%. CAS No. 158081-99-3. Molecular formula: C28H28O4. Mole weight: 428.53. | |
| CP-195543 | CP-195543 is a potent and selective leukotriene B4 antagonist developed as an oral treatment for for inflammatory diseases. Synonyms: 2-[(3S,4R)-3-benzyl-4-hydroxy-3,4-dihydro-2H-chromen-7-yl]-4-(trifluoromethyl)benzoic acid; 2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoic acid; CP 195543; CP-195543; CP195543. Grades: >98%. CAS No. 204981-48-6. Molecular formula: C24H19F3O4. Mole weight: 428.4. | |
| DG051 | DG051 is a potent leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis in the enzyme assay with an IC 50 =47 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 929915-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10825. | |
| Etalocib | LY293111, a novel diaryl ether carboxylic acid derivative, is a potent and selective inhibitor of the lipoxygenase pathway either directly through 5'-lipoxygenase or via antagonism of the leukotriene B4 (LTB4) receptor. LY293111 has antineoplastic activity in a variety of preclinical models. Synonyms: LY293111; VML 295; 2-[3-[3-[(5-Ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propoxy]-2-propylphenoxy]benzoic Acid; 2- [2-Propyl-3- [3- [2-ethyl-4- (4-fluorophenyl) -5-hydroxyphenoxy] propoxy] phenoxy] benzoic acid. Grades: ≥98%. CAS No. 161172-51-6. Molecular formula: C33H33FO6. Mole weight: 544.61. | |
| γ-Linolenic acid ethyl ester | γ-Linolenic acid (GLA) is an ω-6 fatty acid that acts as a weak leukotriene B4 (LTB4) receptor antagonist. Synonyms: Gamma-Linolenic acid ethyl ester; GLA ethyl ester; Ethyl gamma-linolenate. Grades: ≥98%. CAS No. 31450-14-3. Molecular formula: C20H34O2. Mole weight: 306.5. | |
| γ-Linolenic acid methyl ester | γ-Linolenic acid (GLA) is an ω-6 fatty acid that acts as a weak leukotriene B4 (LTB4) receptor antagonist. Synonyms: Methyl GLA; Methyl γ-Linolenate; Methyl gamma-linolenate; Gamma-Linolenic acid methyl ester; Methyl (6Z,9Z,12Z)-octadeca-6,9,12-trienoate; Methyl (Z,Z,Z)-6,9,12-octadecatrienoate. Grades: ≥98%. CAS No. 16326-32-2. Molecular formula: C19H32O2. Mole weight: 292.5. | |
| HZ-52 | A potent, reversible inhibitor of 5-lipoxygenase, blocking leukotriene synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes. It also attenuates leukotriene B4 synthesis, prevents carrageenan-induced pleurisy, and protects against platelet-activating factor-induced shock in mice when given intraperitoneally. Group: Biochemicals. Alternative Names: 2- [ [4- ( [1, 1'-biphenyl] -4-ylamino) -6-chloro-2-pyrimidinyl] thio] octanoic Acid; HZ 52. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| leukotriene-A4 hydrolase | This is a bifunctional zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities. It preferentially cleaves tripeptides at an arginyl bond, with dipeptides and tetrapeptides being poorer substrates (see EC 3.4.11.6, aminopeptidase B). It also converts leukotriene A4 into leukotriene B4, unlike EC 3.3.2.10, soluble epoxide hydrolase, which converts leukotriene A4 into 5,6-dihydroxy-7,9,11,14-icosatetraenoic acid. In vertebrates, five epoxide-hydrolase enzymes have been identified to date: EC 3.3.2.6 (leukotriene A4 hydrolase), EC 3.3.2.7 (hepoxilin-epoxide hydrolase), EC 3.3.2.9 (microsomal epoxide hydrolase), EC 3.3.2.10 (soluble epoxide hydrolase) and EC 3.3.2.11 (cholesterol-5,6-oxide hydrolase). Group: Enzymes. Synonyms: LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase. Enzyme Commission Number: EC 3.3.2.6. CAS No. 90119-07-6. LTA4H. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4003; leukotriene-A4 hydrolase; EC 3.3.2.6; 90119-07-6; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase. Cat No: EXWM-4003. | |
| Leukotriene A4 Hydrolase from Human, Recombinant | Leukotriene A4 Hydrolase human (LTA4H) is a bifunctional zinc metalloenzyme that converts LTA4 into Leukotriene B4, and also demonstrates aminopeptidase activity. Leukotriene B4 is a lipid chemoattractant that plays critical roles in inflammaton, immune responses, host defenses against infections, and lipid homeostasis. Inhibition of LTA4H in a mouse model decreases LTB4 in the airways and attenuates airway inflammation and airway hyperreactivity through modulation of T cell and dendritic cell function. Contains c-terminal his-tag. Applications: Leukotriene a4 hydrolase human (lta4h) is a drug target for anti-inflammation, and for cancer prevention and therapy. it is also suitable for screening inhibitors of leukotriene b4 synthesis. lta4h is used to study allergic asthma and airway hyperresponsiveness. Group: Enzymes. Synonyms: leukotriene-A4 hydrolase; LTA-4 hydrolase; LTA4; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase; EC 3.3.2.6; 90119-07-6. Enzyme Commission Number: EC 3.3.2.6. CAS No. 90119-07-6. LTA4H. Mole weight: mol wt ~69 kDa. Storage: -70°C. Form: Supplied as a solution in 100mM Tris, pH 8.0, containing 20% glycerol and 100mM potassium chloride. Source: E. coli. Species: Human. leukotriene-A4 hydrolase; LTA-4 hydrolase; LTA4; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase; EC 3.3.2.6; 90119-07-6. Cat No: NATE-0419. | |
| Leukotriene B | Leukotriene B4 is a chemokine with roles in inflammation, immunology, the nervous system, brain and skin. And it also shows antiviral activity towards DNA viruses and retroviruses. Synonyms: Leukotriene B4; LTB4; 5,12-Hete; 5,12-Dihete; (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid. Grades: ≥98%. CAS No. 71160-24-2. Molecular formula: C20H32O4. Mole weight: 336.47. | |
| leukotriene-E4 20-monooxygenase | Also acts on N-acetyl-leukotriene E4, but more slowly. Not identical with EC 1.14.13.30 leukotriene-B4 20-monooxygenase. Group: Enzymes. Synonyms: leukotriene-E4 ω-hydroxylase. Enzyme Commission Number: EC 1.14.13.34. CAS No. 111940-51-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0841; leukotriene-E4 20-monooxygenase; EC 1.14.13.34; 111940-51-3; leukotriene-E4 ω-hydroxylase. Cat No: EXWM-0841. | |
| LY-178002 | LY-178002 is a phospholipase A2 inhibitor. It also inhibits leukotriene B4 production. Synonyms: LY 178002; LY178002; LY-178002. 5-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]thiazolidin-4-one;5-(3,5-Bis(tert-butyl)-4-hydroxyphenyl)methylene-4-thiazolidinone;4-Thiazolidinone, 5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-. Grades: >98%. CAS No. 107889-32-7. Molecular formula: C18H25NO2S. Mole weight: 319.46. | |
| LY 213024 | LY 213024 is a potent leukotriene B4 receptor antagonist. Agents which block the production of the leukotrienes have shown reduction of infarct size in animal models of myocardial infarction. Uses: Myocardial infarction. Synonyms: LY 213024; LY213024; LY-213024; 3-[3-(2-carboxyethyl)-4-decoxybenzoyl]benzoic acid. Grades: 98%. CAS No. 117423-95-7. Molecular formula: C27H34O6. Mole weight: 454.56. | |
| LY223982 | This active molecular is benzophenone dicarboxylic acid derivative which is a potent BLT1 receptor antagonist. It inhibits the binding of radiolabeled-LTB4 to isolated human neutrophils and IC50 value is 13.2 nM. LY223982 also inhibits the leukotriene B4 (LTB4)-induced aggregation of guinea human neutrophils. IC50 value is 100 nM. In Aug 1997, phase II for Psoriasis in USA was discontinued. Uses: Psoriasis. Synonyms: LY 223982; LY-223982; LY223982; CGS 23131; SKF 107324; CGS23131; SKF107324; CGS-23131; SKF-107324; 5-(3-Carboxybenzoyl)-2-((6-(4-methoxyphenyl)-5-hexenyl)oxy)benzenepropanoic acid. Grades: 98%. CAS No. 117423-74-2. Molecular formula: C30H30O7. Mole weight: 502.56. | |
| LY255283 | This active molecular is a competitive leukotriene B4 receptor antagonist and IC50 value is about 100 nM. LY 255283 is selective for the BLT2 receptor, since IC50 values at the BLT1 receptor are >10 μM. LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10 μM. It also inhibits the binding of radiolabeled LTB4 to eosinophil membranes and IC50 value is 260 nM. LY255283 reduces airway obstruction in animal models of asthma. However, clinical trials for asthma had been discontinued. Uses: Asthma. Synonyms: LY 255283; LY255283; LY-255283; (1-(5-Ethyl-2-hydroxy-4-(6-methyl-6-(1H-tetrazol-5-yl)heptyloxy)phenyl)ethanone). Grades: 98%. CAS No. 117690-79-6. Molecular formula: C19H28N4O3. Mole weight: 360.45. | |
| LY 255283 | LY255283, a competitive leukotriene B4 receptor antagonist, is used in leukotriene receptor research along with other selective leukotriene receptor agonists and antagonist to identify and differentiate the physiological and cell signaling effects of the leukotriene B4 receptor on processes such as paclitaxel resistance in MCF-7/DOX breast cancer cells, monocyte-derived dendritic cell chemotaxis, and 5-lipoxygenase activity and interleukin-8 production in human neutrophils. LY255283 may be used to help verify that an observed process or cell event is leukotriene B4 receptor-dependent.Antagonists of the chemotactic and inflammatory lipoxygenase product leukotriene B4 (LTB4) have been potential drug development targets for several years.1,2 The tetrazole LY255283 is a competitive antagonist of the BLT2 receptor. It displaces radiolabeled LTB4 from guinea pig lung membrane, with an IC50 of about 100nM.3 LY255283 exhibits IC50 values of ~950nM and >10uM at human recombinant BLT2 and BLT1 receptors, respectively.4 LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10uM, and inhibits the binding of radiolabeled LTB4 to eosinophil membranes with an IC50 of 260nM.1. Group: Biochemicals. Alternative Names: 1-[5-ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]-ethanone. Grades: Highly Purified. CAS No. 117690-79-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H28N4O3, Molecular Weight: 360.5. US Biological Life Sciences. | Worldwide |
| LY-256548 | LY-25648 is a leukotriene B4 antagonist. Synonyms: LY 25648; LY-25648; LY25648; Dihydro-3-methyl-5-(4-hydroxy-3,5-ditert-butylbenzylidene)thiazol-4(5H)-one;LY25648;5-(3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene-N-methyl-4-thiazolidinone;(5Z)-5-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-3-methyl-1,3-thiazolidin-4-one. Grades: >98%. CAS No. 107889-31-6. Molecular formula: C19H27NO2S. Mole weight: 333.49. | |
| LY 292728 | LY 292728, an oxoxanthene derivative, has been found to be a leukotriene B4 receptor antagonist that has once been studied as an antiasthmatic agent. Synonyms: LY 292728; LY292728; LY-292728; CHEMBL292782; 9h-xanthene-4-propanoic acid, 7-carboxy-3-[3-[(5-ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propoxy]-9-oxo-; 9H-Xanthene-4-propanoicacid,7-carboxy-3-[3-[(5-ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propox. Grades: 98%. CAS No. 153034-77-6. Molecular formula: C34H29FO9. Mole weight: 600.60. | |
| LY-306669 | LY-306669, a tetrazol derivative, has been found to be a leukotriene B4 receptor antagonist that was once studied its effect in acute lung injury. Synonyms: LY306669; LY 306669; 5-Ethyl-3'-fluoro-4-((6-methyl-6-(1H-tetrazol-5-yl)heptyl)oxy)-(1,1'-bipenyl)-2-ol monosodium salt; LY-306669; DTXSID70165296; HE116606. Grades: 98%. CAS No. 153227-04-4. Molecular formula: C23H28FN4NaO2. Mole weight: 434.49. | |
| ONO-4057 | ONO-4057 is a leukotriene B4 receptor antagonist originated by Ono Pharmaceutical. ONO-4057 is an Immunologic Factor and Immunosuppressive Agent. Clinical trials for the treatment of Behcet's syndrome, Gastritis and Ulcerative colitis was discontinued. Uses: Behcet's syndrome; gastritis; ulcerative colitis. Synonyms: ONO-4057; ONO4057; ONO 4057; Ono-LB-457; Ono LB 457; OnoLB457; Ono-LB 457; (E)-5-(2-(2-carboxyethyl)-3-((6-(4-methoxyphenyl)hex-5-en-1-yl)oxy)phenoxy)pentanoic acid. Grades: 98%. CAS No. 134578-96-4. Molecular formula: C27H34O7. Mole weight: 470.56. | |
| Parthenolide ((1aR-[1aR*, 4E, 7aS*, -10aS*, -10bR*])-2, 3-6, 7, 7a, 8, 10a, 10b-octahydro-1a, 5-dimethyl-8-methyleneoxireno[9, 10]cyclo deca[1,2-b]furan-9(1aH)-one) | An anti-inflammatory agent. Specifically inhibits activation of NF-kB by preventing the degradation of IkBa and IkBb. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs. Group: Biochemicals. Grades: Highly Purified. CAS No. 20554-84-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 127443 | This active molecular is a Leukotriene B4 antagonist. PD- 127443 is also a 5-lipoxygenase and cyclooxygenase inhibitor and it has been reported to have antiinflammatory effects in vivo. Uses: Antiinflammatory. Synonyms: PD-127443; PD127443; PD 127443; (E)-2,6-di-tert-butyl-4-(2-(5-methyl-1H-pyrazol-3-yl)vinyl)phenol. Grades: 98%. CAS No. 121502-05-4. Molecular formula: C20H28N2O. Mole weight: 312.45. | |
| phylloquinone ω-hydroxylase | A heme-thiolate protein (cytochrome P-450). Isolated from human tissue. The enzyme will also act on menaquinone-4. Prolonged action of CYP4F2, but not CYP4F11, on the ω hydroxyl group oxidizes it to the corresponding carboxylic acid. CYP4F2 also oxidizes leukotriene B4; see EC 1.14.13.30, leukotriene-B4 20-monooxygenase. Group: Enzymes. Synonyms: vitamin K1 ω-hydroxylase; CYP4F2; CYP4F11. Enzyme Commission Number: EC 1.14.13.194. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0794; phylloquinone ω-hydroxylase; EC 1.14.13.194; vitamin K1 ω-hydroxylase; CYP4F2; CYP4F11. Cat No: EXWM-0794. | |
| Ricinelaidic acid | Ricinelaidic acid is an unsaturated fatty acid that acts as a leukotriene B4 (LTB4) receptor antagonist (Ki = 2 μM in porcine neutrophil membranes). Synonyms: 9-Octadecenoic acid, 12-hydroxy-, (9E,12R)-; 12-D-Hydroxy-9-trans-octadecenoic acid; (E,12R)-12-hydroxyoctadec-9-enoic acid; (9E,12R)-12-Hydroxy-9-octadecenoic acid; 9-Octadecenoic acid, 12-hydroxy-, [R-(E)]-. Grades: ≥98%. CAS No. 540-12-5. Molecular formula: C18H34O3. Mole weight: 298.46. | |
| WF11605 | WF11605 is an antagonist of leukotriene B4 (LTB4) isolated from the fungal strain F11605. It inhibited LTB4-induced chemotaxis of rabbit polymorphonuclear leukocytes (PMNLs) with an IC50 value of 1.7 x 10(-7) M and blocked 3H-LTB4 binding to PMNL membranes at 5.6 x 10(-6) M (IC50). It also inhibited LTB4-induced degranulation of rabbit PMNLs at 3.0 x 10(-6) M (IC50). Synonyms: WF 11605; WF-11605. CAS No. 127475-47-2. Molecular formula: C38H60O11. Mole weight: 692.9. | |
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