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Levofloxacincarboxylicacid is used as an antibacterial agent. CAS No. 100986-89-8. Product ID: PAP-0077. Molecular formula: C13H9F2NO4. Category: Hormone drug. Product Keywords: Hormone Series; Levofloxacincarboxylicacid; PAP-0077; Hormone drug; C13H9F2NO4; 100986-89-8. Color: White. EC Number: 1533716-785-6. Physical State: neat. Solubility: DMSO (Slightly). Storage: Sealed in dry,Room Temperature. Applications: Levofloxacincarboxylicacid is a white powder and is an intermediate in the synthesis of the antibiotic levofloxacin. Levofloxacin belongs to the fluoroquinolone class of antibacterial drugs. Boiling Point: 459.2±45.0 °C(Predicted). Melting Point: >300 °C (lit.). Density: 1.61±0.1 g/cm3(Predicted). Product Description: Levofloxacincarboxylicacid is a white powder and is an intermediate in the synthesis of the antibiotic levofloxacin. Levofloxacin belongs to the fluoroquinolone class of antibacterial drugs.
Levofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class[1][2] and is used to treat severe or life-threatening bacterial infections or bacterial infections that have failed to respond to other antibiotic classes.[3][4] It is sold under various brand names, such as Levaquin and Tavanic, the most common. In form of ophthalmic solutions it is known as Oftaquix, Quixin and Iquix. Group: Biochemicals. Alternative Names: (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid, Hemihydrate. Grades: Highly Purified. CAS No. 138199-71-0. Pack Sizes: 100mg. US Biological Life Sciences.
(3S)-10-Fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid is an intermediate in the synthesis of Levofloxacin (L360000), an antibiotic used against gram-negative organisms. Group: Biochemicals. Alternative Names: (S)-10-Fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid. Grades: Highly Purified. CAS No. 117620-84-5. Pack Sizes: 10mg. US Biological Life Sciences.
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9-Piperazine Levofloxacin
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: Levofloxacin EP Impurity I; (-)-(S)-10-Fluoro-2,3-dihydro-3-methyl-9-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid. Grades: > 95%. CAS No. 178912-62-4. Molecular formula: C18H20FN3O4. Mole weight: 361.38.
Defluoro Levofloxacin
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (3S)-2,3-Dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid; Levofloxacin Related Compound F (USP). Grades: > 95%. CAS No. 117620-85-6. Molecular formula: C18H21N3O4. Mole weight: 343.39.
Desmethyl levofloxacin
Heterocyclic Organic Compound. Alternative Names: (3S)-9-Fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid;Desmethyl Levofloxacin;DN 5455. CAS No. 117707-40-1. Molecular formula: C17H18FN3O4. Catalog: ACM117707401.
Desmethyl Levofloxacin-d8 Hydrochloride
A labeled metabolite of Levofloxacin. Group: Biochemicals. Alternative Names: (3S)-9-Fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl-d8)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid Hydrochloride; DN 5455-d8 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desmethyl Levofloxacin Hydrochloride
A metabolite of Levofloxacin. Group: Biochemicals. Alternative Names: (3S)-9-Fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid Hydrochloride; DN 5455 Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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KPI-10
KPI-10, also known as WQ3810, is a new compound currently being studied for its efficacy in the treatment of infections caused by multidrug-resistant bacteria. WQ-3810 demonstrated high potent activity against the antimicrobial-resistant pathogens tested. WQ-3810 (MIC(90)=4 mg/L and 0.06 mg/L, respectively) was also more active than ciprofloxacin (64 mg/L and 2 mg/L) and levofloxacin (32 mg/L and 2 mg/L). Furthermore, WQ-3810 was the most potent among the fluoroquinolones tested against meticillin-resistant Staphylococcus aureus (MRSA) and Neisseria gonorrhoeae, including FQR isolates. Group: Others. Alternative Names: KPI-10; KPI10; KPI 10; WQ3810; WQ-3810; WQ 3810. CAS No. 888032-58-4. Molecular formula: C22H22F3N5O3. Mole weight: 461.45. Appearance: Solid powder. Purity: >98%. IUPACName: 1-(6-Amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isopropylamino)azetidin-1-yl)-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylicacid. Canonical SMILES: O=C (C1=CN (C2=NC (N)=C (F)C=C2F)C3=C (C=C (F)C (N4CC (NC (C)C)C4)=C3C)C1=O)O. Catalog: ACM888032584.
Levofloxacin-d8
Heterocyclic Organic Compound. Alternative Names: (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl-d8)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid Hemihydrate;Levofloxacin-d8;Levofloxacin-D8/ Ofloxacin-D8;Levooxacin-d8. CAS No. 1217716-71-6. Molecular formula: C18H12D8FN3O4. Mole weight: 369.416797424. Catalog: ACM1217716716.
Levofloxacin Diamine
Levofloxacin Diamine is an impurity of Levofloxacin, which is an antibiotic medication used to treat a number of bacterial infections including acute bacterial sinusitis, pneumonia, H. pylori (in combination with other medications), urinary tract infections, chronic prostatitis, and some types of gastroenteritis. Synonyms: 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 10-[(2-aminoethyl)amino]-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-; N,N'-Desethylene-N-Desmethyl Levofloxacin; (S)-10-((2-aminoethyl)amino)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylicacid; N,N-Didesethylene Levofloxacin. Grades: ≥95%. CAS No. 1797510-34-9. Molecular formula: C15H16FN3O4. Mole weight: 321.31.
Levofloxacin Diformyl Impurity
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: N,N'-Desethylene-N,N'-diformyl Levofloxacin; (S)-9-Fluoro-10-[formyl[2-(formylmethylamino)ethyl]amino]-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid. Grades: > 95%. CAS No. 151377-74-1. Molecular formula: C18H18FN3O6. Mole weight: 391.36.
Levofloxacin Ethyl Ester
Levofloxacin Ethyl Ester is an impurity of Levofloxacin. Group: Biochemicals. Alternative Names: (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid Ethyl Ester. Grades: Highly Purified. CAS No. 177472-30-9. Pack Sizes: 100mg. US Biological Life Sciences.
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Levofloxacin hemihydrate
Levofloxacin hemihydrate. Group: Biochemicals. Alternative Names: (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid hemihydrate; Dynaquin; Levofloxacin hydrate. Grades: Highly Purified. CAS No. 138199-71-0. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C18H20FN3O4·½H2O. US Biological Life Sciences.
Worldwide
Levofloxacin Hemihydrate
The hydrate form of Levofloxacin, an Ofloxacin derivative, could be commonly used as an antibacterial agent through influencing DNA replication. It is an antibiotic with activity against gram-negative bacteria. Uses: Anti-bacterial agents. Synonyms: RWJ 25213; RWJ-25213; RWJ25213; (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid Hemihydrate; Dynaquin; Levofloxacin Hydrate. Grades: 98%. CAS No. 138199-71-0. Molecular formula: C18H20FN3O4.1/2H2O. Mole weight: 370.38.
Levofloxacin Impurity 24 (Trifluoroacetate)
Levofloxacin Impurity 24 (Trifluoroacetate). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-3-methyl-9,10-bis(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylicacid compound with 2,2,2-trifluoroacetic acid (1:2). Molecular Formula: C23H31N5O4·2 CF3COOH. Mole Weight: 669.56. Catalog: APB01610.
Levofloxacin Impurity 3
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: 8-fluoro-2,2-dimethyl-9-(4-methylpiperazin-1-yl)-6-oxo-2,6-dihydrooxazolo[5,4,3-ij]quinoline-5-carboxylicacid. Grades: > 95%. Molecular formula: C18H20FN3O4. Mole weight: 361.38.
Levofloxacin Impurity 5
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (S)-9-fluoro-10-hydroxy-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylicacid. Grades: > 95%. Molecular formula: C13H10FNO5. Mole weight: 279.23.
Levofloxacin Impurity 6
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: 9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin; -)-(S)-10-(4-Methyl-1-piperazinyl)-2,3-Dihydro-3-methyl-9-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid. Grades: > 95%. CAS No. 1329833-82-0. Molecular formula: C23H31N5O4. Mole weight: 441.53.
Levofloxacin Impurity 7
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (S)-10-ethoxy-9-fluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylicacid. Grades: > 95%. CAS No. 1607796-83-7. Molecular formula: C15H14FNO5. Mole weight: 307.28.
Levofloxacin Impurity 8
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (R)-Ofloxacin CarboxylicAcid (Dextrofloxacin Difluoro Impurity); (3R)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid. Grades: > 95%. CAS No. 110548-07-7. Molecular formula: C13H9F2NO4. Mole weight: 281.22.
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: N-Desmethyl Levofloxacin ; (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid. Grades: > 95%. CAS No. 117707-40-1. Molecular formula: C17H18FN3O4. Mole weight: 347.35.
Levofloxacin Related Compound C
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: Levofloxacin Ethyl Ester; (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid Ethyl Ester; USP Levofloxacin Related Compound C. Grades: > 95%. CAS No. 177472-30-9. Molecular formula: C20H24FN3O4. Mole weight: 389.43.
N,N'-Desethylene Levofloxacin
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: 9-Fluoro-2,3-dihydro-3-methyl-10-(2-(methylamino)ethylamino)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine-6-carboxylicacid, (S)-. Grades: > 95%. CAS No. 151250-76-9. Molecular formula: C16H18FN3O4. Mole weight: 335.34.
N,N-Desethylene Levofloxacin Hydrochloride
Levofloxacin (L360000) impurity. A photodegradation product of Levofloxacin in aqueous solution. Group: Biochemicals. Alternative Names: (S) -9-Fluoro-2, 3-dihydro-3-methyl-10-[[2- (methylamino) ethyl]amino]-7-oxo-7H-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylicAcid Hydrochloride. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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N,N'-Desethylene-N,N'-diformyl levofloxacin
N,N'-Desethylene-N,N'-diformyl levofloxacin. Group: Biochemicals. Alternative Names: (S) -9-Fluoro-10-[formyl[2- (formylmethylamino) ethyl]amino]-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylicacid. Grades: Highly Purified. CAS No. 151377-74-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H18FN3O6. US Biological Life Sciences.
Worldwide
N,N-Desethylene-N,N-diformyl Levofloxacin
Levofloxacin impurity. A photodegradation product of Levofloxacin in aqueous solution. Group: Biochemicals. Alternative Names: (S) -9-Fluoro-10-[formyl[2- (formylmethylamino) ethyl]amino]-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylicAcid. Grades: Highly Purified. CAS No. 151377-74-1. Pack Sizes: 2.5mg. US Biological Life Sciences.
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N-tert-Butoxycarbonyl Desmethyl Levofloxacin
Protected Levofloxacin metabolite. Group: Biochemicals. Alternative Names: (3S)-N-tert-Butoxycarbonyl-9-fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid; (3S) -10-[4-[ (1, 1-Dimethylethoxy) carbonyl]-1-piperazinyl]-9-fluoro-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylicAcid. Grades: Highly Purified. CAS No. 1330277-19-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
(R)-Levofloxacin
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid. Grades: > 95%. Molecular formula: C18H20FN3O4. Mole weight: 361.38.
(R)-Ofloxacin
Heterocyclic Organic Compound. Alternative Names: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid; (+)-Ofloxacin; (R)-(+)-Ofloxacin; D-Ofloxacin; DR 3354; d-Levofloxacin. CAS No. 100986-86-5. Molecular formula: C18H20FN3O4. Mole weight: 361.37. Catalog: ACM100986865.
(S)-7,8-Difluoro-1-(1-hydroxypropan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylicAcid Ethyl Ester is an intermediate in the synthesis of Levofloxacin (L360000), an antibiotic used against gram-negative organisms. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (2S)-6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylicacid. Grades: > 95 %. CAS No. 100986-89-8. Molecular formula: C13H9F2NO4. Mole weight: 281.21.
Sitafloxacin
Sitafloxacin, a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. In terms of clinical efficacy, oral sitafloxacin was noninferior to oral levofloxacin in the treatment of community-acquired pneumonia or an infectious exacerbation of chronic respiratory tract disease, noninferior to oral tosufloxacin in the treatment of community-acquired pneumonia, and noninferior to oral levofloxacin in the treatment of complicated urinary tract infections, according to the results of randomized, double-blind, multicentre, noninferiority trials. Noncomparative studies demonstrated the efficacy of oral sitafloxacin in otorhinolaryngological infections, urethritis in men, C. trachomatis-associated cervicitis in women and odontogenic infections. Synonyms: 7-((S)-7-amino-5-azaspiro[24]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid; DU 6859; DU-6859; DU6859; DU 6859A; DU-6859A; DU6859A; Sitafloxacin; Sitafloxacin hydrate, Sitafloxacin anhydrous, Trade name: Gracevit. Grades: >98%. CAS No. 127254-12-0. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.81.
Levofloxacin (L360000) derivative. Group: Biochemicals. Alternative Names: 1-[(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate]-2,3,4-tri-O-acetyl- β-D-glucopyranuronic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Levofloxacin Acyl- β-D-glucuronide
A glucuronide metabolite of Levofloxacin. Group: Biochemicals. Alternative Names: 1-[(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate]- β-D-glucopyranuronic Acid; Levofloxacin Glucuronide. Grades: Highly Purified. CAS No. 160962-46-9. Pack Sizes: 1mg, 2.5mg. US Biological Life Sciences.
Worldwide
Levofloxacin Acyl- β-D-glucuronide Methyl Ester
Levofloxacin (L360000) derivative. Group: Biochemicals. Alternative Names: 1-[(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate]- β-D-glucopyranuronic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Levofloxacin-Acyl-D-Glucuronide
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: 1-[(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate]-b-D-glucopyranuronic acid; Levofloxacin glucuronide. Grades: > 95%. CAS No. 160962-46-9. Molecular formula: C24H28FN3O10. Mole weight: 537.49.
Levofloxacin-d8
Labeled S-(-)-Form of Ofloxacin. An antibiotic used against gram-negative organisms. Group: Biochemicals. Alternative Names: (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl-d8)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid Hemihydrate. Grades: Highly Purified. CAS No. 1217716-71-6,unlabeled: 100986-85-4. Pack Sizes: 1mg. Molecular Formula: C??H??D?FN?O?, Molecular Weight: 369.42. US Biological Life Sciences.
Levofloxacin intermediate. Group: Biochemicals. Alternative Names: 9,10-Difluoro-3-(S)-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate. Grades: Highly Purified. CAS No. 106939-34-8. Pack Sizes: 1g. US Biological Life Sciences.
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