Ligand Linker Conjugates Suppliers USA
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Product | Description | |
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E3 ligase Ligand-Linker Conjugates 30 Quick inquiry Where to buy Suppliers range | E3 ligase Ligand-Linker Conjugates 30 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 30 can be used to design PROTAC MDM2 degrade. Synonyms: 4- ( (2- (2- (2- (2-aminoethoxy) ethoxy) ethoxy) ethyl) amino) -2- (2, 6-dioxopiperidin-3-yl) isoindoline-1, 3-dione; Pomalidomide-PEG3-C2-NH2; SCHEMBL19451340; BCP33441; HY-128716; CS-0099510; Cereblon Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 30. Grades: > 98%. CAS No. 2093416-31-8. Molecular formula: C21H28N4O7. Mole weight: 448.47. | |
Azido-Thalidomide Quick inquiry Where to buy Suppliers range | Azido-Thalidomide is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand thalidomide conjugated to an alkyl linker with terminal azide group. Synonyms: E3 ligase Ligand-Linker Conjugates 18; N-(4-azidobutyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide. Grades: ≥98%. CAS No. 2098488-36-7. Molecular formula: C19H20N6O6. Mole weight: 428.405. | |
Maleimide-PEG-FITC Quick inquiry Where to buy Suppliers range | Maleimide-PEG-FITC (MAL-PEG-FITC) is a heterofunctional linker, which has maleimide group on one end for conjugation of thiol-containing ligands, and fluorescent probe (green) on the other end for labeling. Group: Photoactive Polymers. Alternative Names: MAL-PEG-FITC. Product ID: ACMA00018054. | |
Maleimide-PEG-Rhodamine Quick inquiry Where to buy Suppliers range | Maleimide-PEG-Rhodamine (MAL-PEG-RhB) is a heterofunctional linker, which has maleimide group on one end for conjugation of thiol-containing ligands, and fluorescent probe (red) on the other end for labeling. Group: Photoactive Polymers. Alternative Names: MAL-PEG-RhB. Product ID: ACMA00018055. | |
Pomalidomide-C2-NH2 Quick inquiry Where to buy Suppliers range | Pomalidomide-C2-NH2 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. Synonyms: 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; SCHEMBL17884390; TQP0427; Cereblon Ligand-Linker Conjugates 15; HY-128846; Pomalidomide-C2-NH2; Pomalidomide-alkylC2-amine; E3 ligase Ligand 17; 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride. Grades: > 98%. CAS No. 1957235-66-3. Molecular formula: C15H16N4O4. Mole weight: 316.31. | |
Pomalidomide-C4-NH2 Quick inquiry Where to buy Suppliers range | Pomalidomide-C4-NH2 is a synthetic E3 ligase ligand-linker conjugate that incorporates Pomalidomide-based CRBN ligands and linkers used in PROTAC technology. Synonyms: 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-; Thalidomide-NH-C4-NH2. Grades: ≥95%. CAS No. 1957236-34-8. Molecular formula: C17H20N4O4. Mole weight: 344.37. | |
Pomalidomide-PEG3-C2-NH2 hydrochloride Quick inquiry Where to buy Suppliers range | Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker of 3 O(CH2)2 units with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Synonyms: Cereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride. CAS No. 2446474-09-3. Molecular formula: C21H29ClN4O7. Mole weight: 484.93. | |
Thalidomide 4'-ether-alkylC2-amine hydrochloride Quick inquiry Where to buy Suppliers range | Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a short C2 alkyl linker with terminal amine for covalent binding, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Synonyms: Thalidomide - linker 6. Grades: ≥95% by HPLC. CAS No. 2341840-99-9. Molecular formula: C15H16ClN3O5. Mole weight: 353.76. | |
Thalidomide-O-amido-C6-NH2 (TFA) Quick inquiry Where to buy Suppliers range | Thalidomide-O-amido-C6-Amine trifluoroacetate is a PROTAC block consist of Thalidomide linked to alkyl with Amine functional group for conjugation reactions. Synonyms: Thalidomide-O-amido-C6-NH2 (TFA); Cereblon Ligand-Linker Conjugates 11 (TFA); E3 Ligase Ligand-Linker Conjugates 25 (TFA); Thalidomide-O-amido-C6-Amine Trifluoroacetate; N-(6-aminohexyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid. CAS No. 1950635-14-9. Molecular formula: C23H27F3N4O8. Mole weight: 544.48. | |
Thalidomide-O-amido-C8-NH2 (TFA) Quick inquiry Where to buy Suppliers range | Thalidomide-O-amido-C8-NH2 (TFA) is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology. Synonyms: E3 Ligase Ligand-Linker Conjugates 17. CAS No. 1950635-16-1. Molecular formula: C25H31F3N4O8. Mole weight: 572.53. | |
Thalidomide-O-C4-NH2 hydrochloride Quick inquiry Where to buy Suppliers range | Thalidomide-O-C4-NH2 hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C4 alkyl linker with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Synonyms: Thalidomide-linker 9. Grades: ≥95% by HPLC. CAS No. 2376990-29-1. Molecular formula: C17H20ClN3O5. Mole weight: 381.81. | |
Thalidomide, propargyl Quick inquiry Where to buy Suppliers range | Thalidomide, propargyl is a cereblon-recruiting ligand consisting of an E3 ubiquitin ligase thalidomide conjugated to an alkyne linker ready for a target protein ligand. It has been used in PROTAC technology for target protein degradation. Synonyms: 2-(2,6-Dioxo-3-piperidinyl)-4-(2-propyn-1-yloxy)-1H-isoindole-1,3(2H)-dione. Grades: ≥98%. CAS No. 2098487-39-7. Molecular formula: C16H12N2O5. Mole weight: 312.28. | |
Thiol-PEG-Rhodamine Quick inquiry Where to buy Suppliers range | Thiol-PEG-Rhodamine (RhB-PEG-SH) is a heterofunctional linker, which has thiol group on one end for conjugation of thiol-containing ligands, and fluorescent probe (red) on the other end for labeling. Group: Photoactive Polymers. Alternative Names: RhB-PEG-SH. Product ID: ACMA00018088. | |
VH 032-linker 6 Quick inquiry Where to buy Suppliers range | VH 032-linker 6 is a von-Hippel-Lindau protein ligand (VHL) conjugated to a PEGylated crosslinker with terminal alkyne for PROTAC technology. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: VH032-PEG3-acetylene; (2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 2098799-80-3. Molecular formula: C31H42N4O7S. Mole weight: 614.75. |