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| Product | Description | |
|---|---|---|
| E3 ligase Ligand-Linker Conjugates 30 | E3 ligase Ligand-Linker Conjugates 30 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 30 can be used to design PROTAC MDM2 degrade. Synonyms: 4- ( (2- (2- (2- (2-aminoethoxy) ethoxy) ethoxy) ethyl) amino) -2- (2, 6-dioxopiperidin-3-yl) isoindoline-1, 3-dione; Pomalidomide-PEG3-C2-NH2; SCHEMBL19451340; BCP33441; HY-128716; CS-0099510; Cereblon Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 30. Grades: > 98%. CAS No. 2093416-31-8. Molecular formula: C21H28N4O7. Mole weight: 448.47. |  |
| 1-Boc-azetidine-3-carboxylic acid | 1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142253-55-2. Pack Sizes: 1 g; 5 g. Product ID: HY-40141. |  |
| 1-Cbz-azetidine-3-carboxylic acid | 1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 97628-92-7. Pack Sizes: 10 g; 25 g. Product ID: HY-W004868. | |
| 1-N-Boc-3-hydroxyazetidine | 1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-N-Boc-3-hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 141699-55-0. Pack Sizes: 25 g; 50 g. Product ID: HY-40142. | |
| (1R)-Deruxtecan | (1R)-Deruxtecan is a drug-linker conjugates for ADC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2270986-87-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13631O. | |
| 2-(2-(2-Aminoethoxy)ethoxy)acetic acid | H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB). H2N-PEG2-CH2COOH is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs. Synonyms: Amino-PEG2-CH2CO2H; Amino-PEG2-CH2COOH; Amino-PEG2-acetic acid. Grades: ≥95%. CAS No. 134978-97-5. Molecular formula: C6H13NO4. Mole weight: 163.17. | |
| (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride | cis-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 77449-94-6. Pack Sizes: 25 g; 100 g. Product ID: HY-76104. | |
| (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid | N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 147266-92-0. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-77593. | |
| 6-Azidohexanoic acid NHS ester | A noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-C5-NHS ester. Grades: ≥ 95% (HPLC). CAS No. 866363-70-4. Molecular formula: C10H14N4O4. Mole weight: 254.24. | |
| AEEA-AEEA | AEEA-AEEA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: 17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid. CAS No. 1143516-05-5. Molecular formula: C12H24N2O7. Mole weight: 308.33. | |
| Amino-PEG3-t-butyl acetate | NH2-PEG3-C1-Boc is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 5 can be used in the synthesis of a series of PROTACs. NH2-PEG3-C1-Boc is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates, PROTACs and drug delivery methods. Synonyms: NH2-PEG3-C1-Boc; PROTAC Linker 5; Amino-PEG3-CH2CO2-t-butyl ester; H2N-PEG3-CH2COOtBu; Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester. Grades: >95%. CAS No. 189808-70-6. Molecular formula: C12H25NO5. Mole weight: 263.33. | |
| Amino-PEG4-alcohol | Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Amino peg linkers. Alternative Names: 11-Amino-3,6,9-trioxaundecanol. CAS No. 86770-74-3. Molecular formula: C8H19NO4. Mole weight: 193.24. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCO)N. Density: 1.1±0.1 g/cm3. Catalog: ACM86770743. |  |
| Amino-PEG4-CH2COOH | Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Amino peg linkers. Alternative Names: Amino-PEG4-acetic acid. CAS No. 195071-49-9. Molecular formula: C10H21NO6. Mole weight: 251.28. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2- (2-Aminoethoxy) ethoxy]ethoxy]ethoxy]acetic acid. Canonical SMILES: C(COCCOCCOCCOCC(=O)O)N. Density: 1.156±0.06 g/cm3. Catalog: ACM195071499. | |
| Amino-PEG6-alcohol | Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Amino peg linkers. Alternative Names: Amino-PEG6-OH. CAS No. 39160-70-8. Molecular formula: C12H27NO6. Mole weight: 281.35. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2-[2- (2-Aminoethoxy) ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCOCCO)N. Density: 1.1±0.1 g/cm3. Catalog: ACM39160708. | |
| Azetidine-3-carboxylic acid | Azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2. Uses: Scientific research. Group: Signaling pathways. CAS No. 36476-78-5. Pack Sizes: 10 g; 25 g. Product ID: HY-Y0530. | |
| Azido-PEG10-amine | Azido-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N3-PEG10-CH2CH2NH2; 32-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-amine; O-(2-Aminoethyl)-O-(2-azidoethyl)nonaethylene Glycol; N3-PEG10-NH2. Grades: >97%. CAS No. 912849-73-1. Molecular formula: C22H46N4O10. Mole weight: 526.62. | |
| Azido-PEG3-NHS ester | N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Azido peg linkers. Alternative Names: N3-PEG3-C2-NHS ester. CAS No. 1245718-89-1. Molecular formula: C13H20N4O7. Mole weight: 344.32. Appearance: Solid or viscous liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCOCCN=[N+]=[N-]. Catalog: ACM1245718891. | |
| Azido-PEG4-NHS ester | N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Azido peg linkers. Alternative Names: N3-PEG4-C2-NHS ester. CAS No. 944251-24-5. Molecular formula: C15H24N4O8. Mole weight: 388.37. Appearance: Solid or viscous liquid. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2- (2-azidoethoxy) ethoxy]ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC (=O)N (C1=O)OC (=O)CCOCCOCCOCCOCCN=[N+]=[N-]. Catalog: ACM944251245. | |
| Azido-PEG5-alcohol | Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Group: Azido peg linkers. Alternative Names: 1-Azidohexaethylene glycol. CAS No. 86770-68-5. Molecular formula: C10H21N3O5. Mole weight: 263.29. Appearance: Oil. Purity: >90%. IUPACName: 2-[2-[2-[2- (2-Azidoethoxy) ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCO)N=[N+]=[N-]. Catalog: ACM86770685. | |
| Azido-PEG6-alcohol | Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Azido peg linkers. Alternative Names: N3-PEG6-OH. CAS No. 86770-69-6. Molecular formula: C12H25N3O6. Mole weight: 307.34. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2-[2- (2-Azidoethoxy) ethoxy]ethoxy]ethoxy]ethoxy]ethanol. Canonical SMILES: C(COCCOCCOCCOCCOCCO)N=[N+]=[N-]. Catalog: ACM86770696. | |
| Azido-PEG8-amine | Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol; N3-PEG8-CH2CH2NH2; Azido-PEG8-NH2; N3-PEG8-NH2; 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine. Grades: ≥90%. CAS No. 857891-82-8. Molecular formula: C18H38N4O8. Mole weight: 438.52. | |
| Azido-Thalidomide | Azido-Thalidomide is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand thalidomide conjugated to an alkyl linker with terminal azide group. Synonyms: E3 ligase Ligand-Linker Conjugates 18; N-(4-azidobutyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide. Grades: ≥98%. CAS No. 2098488-36-7. Molecular formula: C19H20N6O6. Mole weight: 428.405. | |
| β-GalNAc-PEG4-Azide | Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry. Uses: β-galnac-peg4-azide is a functionalized asialoglycoprotein receptor (asgpr) ligand for lysosomal targeting chimera (lytac) research and development; incorporates a single asgpr ligand with a peg4 linker and azide group reactive handle ready for conjugation. it can be used as a building block for multivalent compounds to enhance asgpr binding. upon binding to asgpr, β-galnac conjugates are efficiently internalized via asgpr-mediated endocytosis. β-galnac conjugation can be employed as a strategy to effectively deliver cargo such as rna or cas9 complexes in a cell-specific manner to hepatocytes. can be used to generate lytacs, or labeled with dye for tissue imaging. Group: Galnac conjugates. Alternative Names: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 2-(acetylamino)-2-deoxy-β-D-galactopyranoside. CAS No. 879004-92-9. Molecular formula: C16H30N4O9. Mole weight: 422.44. Purity: >95% (HPLC). Canonical SMILES: [N-]=[N+]=NCCOCCOCCOCCO[C@H]1[C@@H] ([C@H] ([C@H] ([C@H] (O1)CO)O)O)NC (C)=O. Catalog: ACM879004929. | |
| Biotin-PEG1-NH2 | Biotin-PEG1-NH2 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 811442-85-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W096135. | |
| BMPS | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-62-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-42146. | |
| Boc-Cystamine | Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 485800-26-8. Pack Sizes: 100 mg; 250 mg. Product ID: HY-140098. | |
| Boc-Gly-Gly-Phe-Gly-OH | Boc-Gly-Gly-Phe-Gly-OH is a self-assembly of N- and C-protected tetrapeptide. It is also a protease-cleavable linker for antibody-drug conjugates (ADCs). Synonyms: N-tert-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-glycine; N-(tert-butoxycarbonyl)-glycylglycyl-L-phenylalanylglycine; (S)-12-Benzyl-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oic acid. Grades: >95%. CAS No. 187794-49-6. Molecular formula: C20H28N4O7. Mole weight: 436.46. | |
| BOC-L-Hydroxyproline | Boc-L-Hydroxyproline 13726-69-7 is Powder. it is also known as N-Boc-L-Hydroxyproline and trans-N-tert-Butoxycarbonyl-4-hydroxy-L-proline. it is use in API Synthesis and Synthesis Industry. Storage: Keep container tightly closed. CAS No. 13726-69-7. Product ID: PAP-0013. Molecular formula: C10H17NO5. Category: Amino acid. Product Keywords: Amino Acid Series; BOC-L-Hydroxyproline; PAP-0013; Amino acid; C10H17NO5; 13726-69-7. Color: White to off-white. EC Number: 604-011-7. Physical State: Powder. Solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. Storage: Keep in dark place,Sealed in dry,Room Temperature. Applications: Boc-Hyp-OH is a non-cleavable ADC connector used to synthesize antibody drug conjugates (ADCs). Boc Hyp OH is also an alkyl chain-based PROTAC linker that can be used to synthesize PROTAC. Boiling Point: 390.9±42.0 °C(Predicted). Melting Point: 123-127 °C(lit.). Density: 1.312±0.06 g/cm3(Predicted). Product Description: Boc-Hyp-OH is a non-cleavable ADC connector used to synthesize antibody drug conjugates (ADCs). Boc Hyp OH is also an alkyl chain-based PROTAC linker that can be used to synthesize PROTAC. |  |
| Boc-Val-Cit-OH | Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: (2S) -5- (carbamoylamino) -2- [ [ (2S) -3-methyl-2- [ (2-methylpropan-2-yl) oxycarbonylamino] butanoyl] amino] pentanoic acid. Grades: ≥95.0%. CAS No. 870487-08-4. Molecular formula: C16H30N4O6. Mole weight: 374.43. | |
| BS3 Crosslinker | BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82436-77-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124329. | |
| Dap-NE hydrochloride | Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2019182-02-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-78932A. | |
| DBCO-acid | DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE. Uses: White to light yellow powder to crystal. Synonyms: 11,12-Didehydro-gamma-oxodibenz[b,f]azocine-5(6H)-butanoic acid. Grades: > 98.0 %. CAS No. 1353016-70-2. Molecular formula: C19H15NO3. Mole weight: 305.33. | |
| DBCO-acid | DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353016-70-2. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-42972. | |
| DBCO-amine | DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1255942-06-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W000423. | |
| DBCO-Maleimide | DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1395786-30-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-116270. | |
| DBCO-NHS ester | DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353016-71-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-42973. | |
| DBCO-PEG3-NHS ester | DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163772-16-3. Pack Sizes: 25 mg; 50 mg. Product ID: HY-156507. | |
| DBCO-PEG4-DBCO | DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2182601-68-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-130346. | |
| DBCO-PEG4-Maleimide | DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1480516-75-3. Pack Sizes: 25 mg. Product ID: HY-120770. | |
| DBCO-PEG5-NHS ester | DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1] [2]. DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2144395-59-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126885. | |
| DBCO-Sulfo-Link-biotin | DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1363444-70-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-130810. | |
| DBCO-Sulfo-NHS ester sodium | DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1400191-52-7. Pack Sizes: 5 mg. Product ID: HY-123687. | |
| Disuccinimidyl suberate Crosslinker | Disuccinimidyl suberate Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68528-80-3. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W019543. | |
| DL-01 formic | DL-01 formic is a drug-linker conjugates for ADC that can be used for the synthesis of ADCs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2964513-44-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-155870A. | |
| Docosanedioic acid | Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Natural products. CAS No. 505-56-6. Pack Sizes: 250 mg; 1 g; 5 g; 10 g. Product ID: HY-W034918. | |
| DSP Crosslinker | DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Disuccinimido dithiobispropionate; Di(N-succinimidyl) 3,3'-dithiodipropionate. Grades: 98.0 %. CAS No. 57757-57-0. Molecular formula: C14H16N2O8S2. Mole weight: 404.42. | |
| DSS Crosslinker | DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Disuccinimidyl suberate; bis(2,5-dioxopyrrolidin-1-yl) octanedioate; Suberic acid bis(N-hydroxysuccinimide ester). Grades: >98.0%. CAS No. 68528-80-3. Molecular formula: C16H20N2O8. Mole weight: 368.34. | |
| DTSSP Crosslinker | DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81069-02-5. Pack Sizes: 5 mg. Product ID: HY-126349. | |
| DTSSP Crosslinker | DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: It is a water-soluble, thiol cleavable, homobifunctional and amine-reactive crosslinking agent. Synonyms: 3,3'-Dithiobis(sulphosuccinimidyl propionate); 3-pyrrolidinesulfonic acid, 1,1'-[dithiobis[(1-oxo-3,1-propanediyl)oxy]]bis[2,5-dioxo-. Grades: ≥97.0%. CAS No. 81069-02-5. Molecular formula: C14H16N2O14S4. Mole weight: 564.54. | |
| Eicosanedioic acid | Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis. Uses: Scientific research. Group: Natural products. CAS No. 2424-92-2. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W034595. | |
| Fmoc-Ala-Ala-PAB | Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1384263-83-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-148462. | |
| Fmoc-Asp-NH2 | Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Fmoc-L-Isoasparagine; Fmoc-Isoasn-OH; Butanoic acid, 4-amino-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-oxo-, (3S)-. Grades: ≥98.0%. CAS No. 200335-40-6. Molecular formula: C19H18N2O5. Mole weight: 354.36. | |
| Fmoc-azetidine-3-carboxylic acid | Fmoc-azetidine-3-carboxylic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 193693-64-0. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W011277. | |
| Fmoc-D-Trp(Boc)-OH | Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 163619-04-3. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-79129. | |
| Fmoc-Gly-Gly-OH | Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35665-38-4. Pack Sizes: 1 g; 10 g; 25 g; 100 g; 500 g. Product ID: HY-W023121. | |
| Fmoc-Gly-Gly-OH | Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N-Fmoc-L-glycylglycine; 2- (2- ( ( ( (9H-Fluoren-9-yl) methoxy) carbonyl) amino) acetamido) acetic acid. Grades: >99.3%. CAS No. 35665-38-4. Molecular formula: C19H18N2O5. Mole weight: 354.36. | |
| Fmoc-Lys-OH hydrochloride | Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 139262-23-0. Pack Sizes: 1 g; 5 g. Product ID: HY-W010975. | |
| Fmoc-N-amido-PEG2-acetic acid | Fmoc-AEEA-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Fmoc-NH-PEG2-CH2COOH; Fmoc-8-amino-3,6-dioxaoctanoic acid; [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid; FMOC-AEEA; 12- (9H- Fluoren- 9- yl) - 10- oxo-3, 6, 11- trioxa- 9- azadodecanoic Acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic Acid; 8-(9-Fluorenylmethoxycarbonylamino)-3,6-dioxaoctanoic Acid; 9-Fluorenylmethoxycarbonyl-8-amino-3,6-dioxaoctanoic Acid; 2,7,10-Trioxa-4-azadodecan-12-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-. Grades: 98%. CAS No. 166108-71-0. Molecular formula: C21H23NO6. Mole weight: 385.41. | |
| Fmoc-NH-PEG4-CH2COOH | Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Fmoc peg linkers. Alternative Names: 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid. CAS No. 437655-95-3. Molecular formula: C25H31NO8. Mole weight: 473.5. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2-[2- (9H-Fluoren-9-ylmethoxycarbonylamino) ethoxy]ethoxy]ethoxy]ethoxy]acetic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NCCOCCOCCOCCOCC (=O)O. Density: 1.235±0.06 g/cm3. Catalog: ACM437655953. | |
| Fmoc-NH-PEG8-CH2COOH | Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG8-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 868594-52-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-133063. | |
| Fmoc-Val-Ala-PAB-PNP | Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1394238-92-6. Pack Sizes: 100 mg; 250 mg. Product ID: HY-136136. | |
| Glembatumumab vedotin | Glembatumumab vedotin (CDX-011) is an ADC ( antibody-drug conjugates (ADCs) ) comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDX-011; CR011-vcMMAE. CAS No. 1182215-65-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141604. | |
| H-Glu-OtBu | H-Glu-OtBu is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Glu-OtBu is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2. Uses: Scientific research. Group: Signaling pathways. CAS No. 45120-30-7. Pack Sizes: 1 g; 5 g. Product ID: HY-W018154. | |
| Hydroxy-PEG10-t-butyl ester | Hydroxy-PEG10-t-butyl ester is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: T-butyl ester peg linkers. Alternative Names: HO-PEG10-tBu. CAS No. 778596-26-2. Molecular formula: C27H54O13. Mole weight: 586.7. Appearance: Liquid. Purity: >90%. IUPACName: Tert-butyl 3- [2- [2- [2- [2- [2- [2- [2- [2- [2- (2-hydroxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] propanoate. Canonical SMILES: CC (C) (C) OC (=O) CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO. Catalog: ACM778596262. | |
| Hydroxy-PEG4-acid | Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Acid peg linkers. Alternative Names: Hydroxy-PEG4-propionic acid. CAS No. 937188-59-5. Molecular formula: C11H22O7. Mole weight: 266.29. Appearance: Liquid. Purity: >90%. IUPACName: 3-[2-[2-[2- (2-Hydroxyethoxy) ethoxy]ethoxy]ethoxy]propanoic acid. Canonical SMILES: C(COCCOCCOCCOCCO)C(=O)O. Density: 1.2±0.1 g/cm3. Catalog: ACM937188595. | |
| IM-2 | IM-2 is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2813269-89-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160157. | |
| Maleimide-PEG4-NHS | This molecular is a sulfhydryl and amine reactive heterofuncational PEG linker. The chemical bonds that formed through Maleimide-PEG4-NHS linker are very stable. The NHS ester reacts with amino groups at pH 7-9 to form stable amide bond. In addiction, the maleimide reacts with thiol groups at pH 6.5-7.5 to form stable thiol-ether bond. Maleimide-PEG4-NHS is a very useful linker for various biomolecule crosslinking applications (such as to make ADCs (antibody drug conjugates.)). Uses: Useful linker for various biomolecule crosslinking applications. Synonyms: Maleimide-PEG4-NHS; MAL-PEG4-NHS; Maleimide PEG NHS; MAL-PEG-NHS; Maleimido-Tetra(Ethylene Glycol)?-Acetic Acid NHS ester;2,5-dioxopyrrolidin-1-yl 14-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxatetradecanoate. Grades: 98%. CAS No. 1286754-10-6. Molecular formula: C18H24N2O10. Mole weight: 428.39. | |
| Mal-PEG2-acid | Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Other peg linkers. Alternative Names: Mal-PEG2-CH2CH2COOH. CAS No. 1374666-32-6. Molecular formula: C11H15NO6. Mole weight: 257.24. Appearance: Liquid. Purity: >90%. IUPACName: 3-[2-[2-(2,5-Dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid. Canonical SMILES: C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O. Density: 1.3±0.1 g/cm3. Catalog: ACM1374666326. | |
| Mal-PEG2-acid | Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule [1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374666-32-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-130442. | |
| Mal-PEG2-Val-Cit-PABA-PNP | Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345681-52-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131156. | |
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