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| Product | Description | |
|---|---|---|
| lipopolysaccharide 3-α-galactosyltransferase | Transfers α-D-galactosyl residues to D-glucose in the partially completed core of lipopolysaccharide [cf. EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)]. Group: Enzymes. Synonyms: UDP-galactose:lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:polysaccharide galactosyltransferase; uridine diphosphate galactose:lipopolysaccharide α-3-galactosyltransferase; uridine diphosphogalactose-lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:lipopolysaccharide 3-α-D-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.44. CAS No. 9073-98-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2590; lipopolysaccharide 3-α-galactosyltransferase; EC 2.4.1.44; 9073-98-7; UDP-galactose:lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:polysaccharide galactosyltransferase; uridine diphosphate galactose:lipopolysaccharide α-3-galactosyltransferase; uridine diphosphogalactose-lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:lipopolysaccharide 3-α-D-galactosyltransferase. Cat No: EXWM-2590. |  |
| Lipopolysaccharide from Porphyromonas gingivalis | Lipopolysaccharide from Porphyromonas gingivalis. Group: Polysaccharide. |  |
| Lipopolysaccharide from Porphyromonas gingivalis | purified by phenol extraction. Group: Polysaccharide. |  |
| lipopolysaccharide glucosyltransferase I | Transfers glucosyl residues to the backbone portion of lipopolysaccharide [cf. EC 2.4.1.44 (lipopolysaccharide 3-α-galactosyltransferase, EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)]. Group: Enzymes. Synonyms: UDP-glucose:lipopolysaccharide glucosyltransferase I; lipopolysaccharide glucosyltransferase; uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I; uridine diphosphoglucose-lipopolysaccharide glucosyltransferase. Enzyme Commission Number: EC 2.4.1.58. CAS No. 9074-00-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2603; lipopolysaccharide glucosyltransferase I; EC 2.4.1.58; 9074-00-4; UDP-glucose:lipopolysaccharide glucosyltransferase I; lipopolysaccharide glucosyltransferase; uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I; uridine diphosphoglucose-lipopolysaccharide glucosyltransferase. Cat No: EXWM-2603. | |
| lipopolysaccharide glucosyltransferase II | Transfers glucosyl residues to the D-galactosyl-D-glucosyl side-chains in the partially completed core of lipopolysaccharides. cf. EC 2.4.1.44 (lipopolysaccharide 3-α-galactosyltransferase), EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase) and EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I). Group: Enzymes. Synonyms: uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase. Enzyme Commission Number: EC 2.4.1.73. CAS No. 51004-27-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2616; lipopolysaccharide glucosyltransferase II; EC 2.4.1.73; 51004-27-4; uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase. Cat No: EXWM-2616. | |
| lipopolysaccharide N-acetylglucosaminyltransferase | Transfers N-acetylglucosaminyl residues to a D-galactose residue in the partially completed lipopolysaccharide core [cf. EC 2.4.1.44 (lipopolysaccharide 3-α-galactosyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)]. Group: Enzymes. Synonyms: UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.56. CAS No. 37277-64-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2601; lipopolysaccharide N-acetylglucosaminyltransferase; EC 2.4.1.56; 37277-64-8; UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2601. | |
| lipopolysaccharide N-acetylmannosaminouronosyltransferase | Involved in the biosynthesis of common antigen in Enterobacteriaceae. Group: Enzymes. Synonyms: ManNAcA transferase; uridine diphosphoacetyl mannosaminuronate-acetyl glucosaminyl pyrophosphoryl undecaprenol acetylmannosaminuronosyltransferase; UDP-N-acetyl-β-D-mannosaminouronate:lipid I N-acetyl-β-D-mannosaminouronosyltransferase (incorrect). Enzyme Commission Number: EC 2.4.1.180. CAS No. 113478-30-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2406; lipopolysaccharide N-acetyl mannosaminouronosyl transferase; EC 2.4.1.180; 113478-30-1; ManNAcA transferase; uridine diphosphoacetyl mannosaminuronate-acetyl glucosaminyl pyrophosphoryl undecaprenol acetylmannosaminuronosyltransferase; UDP-N-acetyl-β-D-mannosaminouronate:lipid I N-acetyl-β-D-mannosaminouronosyltransferase (incorrect). Cat No: EXWM-2406. | |
| Lipopolysaccharides | Lipopolysaccharides Inhibitor. Uses: Scientific use. Product Category: T11855. CAS No.: |  |
| Lipopolysaccharides from Escherichia coli | Lipopolysaccharides produced by Escherichia coli are endotoxins. Synonyms: Lipopolysaccharide E. Coli; Escherichia coli lipopolysaccharides; Lipopolysaccharides, Escherichiacoli; Citopyros; Escherichia coli lipopolysaccharide; Lipopolysaccharide, Escherichia coli; Lipopolysaccharides, Escherichia coli. CAS No. 93572-42-0. |  |
| Lipopolysaccharides from Escherichia coli K-235 | Lipopolysaccharides from Escherichia coli K-235. Group: Polysaccharide. | |
| Lipopolysaccharides from Escherichia coli O111:B4 | Lipopolysaccharides from Escherichia coli O111:B4. Group: Polysaccharide. | |
| Lipopolysaccharides from Escherichia coli O111:B4 | Ready Made solution, 1 mg/mL, 0.2 ?m filtered. Group: Fluorescence/luminescence spectroscopy. | |
| Lipopolysaccharides from Escherichia coli O127:B8 | Lipopolysaccharides from Escherichia coli O127:B8. Group: Polysaccharide. | |
| Lipopolysaccharides from Escherichia coli O127:B8 | Ready Made solution, 1 mg/mL, 0.2 ?m filtered. Group: Polysaccharide. | |
| Lipopolysaccharides from Escherichia coli O128:B12 | Lipopolysaccharides from Escherichia coli O128:B12. Group: Polysaccharide. | |
| Lipopolysaccharides from Escherichia coli O26:B6 | Lipopolysaccharides from Escherichia coli O26:B6. Group: Polysaccharide. | |
| Lipopolysaccharides from Escherichia coli O26:B6 | Ready Made solution, 1 mg/mL, 0.2 ?m filtered. Group: Polysaccharide. | |
| Lipopolysaccharides from Escherichia coli O55:B5 | Lipopolysaccharides from Escherichia coli O55:B5. Group: Polysaccharide. | |
| Lipopolysaccharides from Escherichia coli O55:B5 | Ready Made solution, 1 mg/mL, 0.2 ?m filtered. Group: Polysaccharide. | |
| Lipopolysaccharides from Klebsiella pneumoniae | Lipopolysaccharides from Klebsiella pneumoniae. Group: Polysaccharide. | |
| Lipopolysaccharides from Klebsiella pneumoniae | purified by phenol extraction. Group: Polysaccharide. | |
| Lipopolysaccharides - from Porphyromonas gingivalis | Lipopolysaccharides from Porphyromonas gingivalis are essential tools used as experimental models to study and understand the pathogenesis of chronic periodontitis, a common oral disease caused by this bacterium. Synonyms: LPS-PG. | |
| Lipopolysaccharides from Proteus mirabilis | Lipopolysaccharides from Proteus mirabilis. Group: Polysaccharide. | |
| Lipopolysaccharides from Proteus mirabilis | purified by phenol extraction. Group: Polysaccharide. | |
| Lipopolysaccharides from Proteus vulgaris | Lipopolysaccharides from Proteus vulgaris. Group: Polysaccharide. | |
| Lipopolysaccharides from Proteus vulgaris | purified by phenol extraction. Group: Polysaccharide. | |
| Lipopolysaccharides from Pseudomonas aeruginosa 10 | Lipopolysaccharides from Pseudomonas aeruginosa 10. Group: Polysaccharide. | |
| Lipopolysaccharides from Salmonella enterica serotype abortus equi | Lipopolysaccharides from Salmonella enterica serotype abortus equi. Group: Polysaccharide. | |
| Lipopolysaccharides from Salmonella enterica serotype enteritidis | Lipopolysaccharides from Salmonella enterica serotype enteritidis. Group: Polysaccharide. | |
| Lipopolysaccharides from Salmonella enterica serotype minnesota | Lipopolysaccharides from Salmonella enterica serotype minnesota. Group: Polysaccharide. | |
| Lipopolysaccharides from Salmonella enterica serotype typhimurium | Lipopolysaccharides from Salmonella enterica serotype typhimurium. Group: Polysaccharide. | |
| Lipopolysaccharides from Salmonella typhosa | Lipopolysaccharides from Salmonella typhosa. Group: Polysaccharide. | |
| Lipopolysaccharides from Serratia marcescens | Lipopolysaccharides from Serratia marcescens. Group: Polysaccharide. | |
| Lipopolysaccharides from Serratia marcescens | purified by phenol extraction. Group: Polysaccharide. | |
| Lipopolysaccharides (rough strains) from Escherichia coli EH100 (Ra mutant) | Lipopolysaccharides (rough strains) from Escherichia coli EH100 (Ra mutant). Group: Polysaccharide. | |
| Lipopolysaccharides (rough strains) from Escherichia coli F583 (Rd mutant) | Lipopolysaccharides (rough strains) from Escherichia coli F583 (Rd mutant). Group: Polysaccharide. | |
| Lipopolysaccharides (rough strains) - from Escherichia coli J5 (Rc mutant) | | |
| Lipopolysaccharides (rough strains) from Escherichia coli J5 (Rc mutant) | Lipopolysaccharides (rough strains) from Escherichia coli J5 (Rc mutant). Group: Polysaccharide. | |
| Lipopolysaccharides (rough strains) from Salmonella enterica serotype minnesota Re 595 (Re mutant) | Lipopolysaccharides (rough strains) from Salmonella enterica serotype minnesota Re 595 (Re mutant). Group: Polysaccharide. | |
| Lipopolysaccharides (rough strains) from Salmonella enterica serotype typhimurium SL1181 | Lipopolysaccharides (rough strains) from Salmonella enterica serotype typhimurium SL1181. Group: Polysaccharide. | |
| Lipopolysaccharides (rough strains) from Salmonella enterica serotype typhimurium TV119 (Ra mutant) | Lipopolysaccharides (rough strains) from Salmonella enterica serotype typhimurium TV119 (Ra mutant). Group: Polysaccharide. | |
| lipopolysaccharide-transporting ATPase | ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. Enzymes of Gram-negative bacteria that export lipo-oligosaccharides and lipopolysaccharides. Group: Enzymes. Enzyme Commission Number: EC 7.5.2.5 (Formerly EC 3.6.3.39). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4677; lipopolysaccharide-transporting ATPase; EC 3.6.3.39. Cat No: EXWM-4677. | |
| 1,3,5,7-Tetramethyl-8-(C3-COOH)4,4-difluoro-4-bora-3a,4a-diaza-s-indacene | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: 4-(4,4-Difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)-butyric Acid. CAS No. 878674-84-1. Molecular formula: C17H22BF2N2O2. Mole weight: 335.18. | |
| 2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one | 2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one is an related compound of the flavanoid Quercetin (Q509500) with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 357194-03-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C28H18O7. US Biological Life Sciences. |  Worldwide |
| 2,6-Dichlorobenzyl Bromide | 2,6-Dichlorobenzyl Bromide is used in the preparation of potent epoxide hydrolase inhibitors. Has shown thus far to relieve hypotension in lipopolysaccharide deficient murine models. As well they have been used in the synthesis of anti-HIV drugs based on diaryltriazine (DATA) analogues. Group: Biochemicals. Alternative Names: 2-(Bromomethyl)-1,3-dichlorobenzene; α-Bromo-2,6-dichloro-toluene; 1-Bromomethyl-2,6-dichlorobenzene; 2,6-Dichloro-α-bromotoluene; 2,6-Dichlorobenzyl Bromide; 2-(Bromomethyl)-1,3-dichlorobenzene; NSC 93898; α-Bromo-2,6-dichlorotoluene. Grades: Highly Purified. CAS No. 20443-98-5. Pack Sizes: 50g. US Biological Life Sciences. | Worldwide |
| 2,6-Diiodo-1,3,5,7-tetramethyl-8-phenyl-4,4-difluoroboradiazasindacene | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: 5,5-Difluoro-2,8-diiodo-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide. CAS No. 1083009-44-2. Molecular formula: C19H17BF2I2N2. Mole weight: 575.974. | |
| 2-Keto-3-deoxyoctonate ammonium salt | 2-Keto-3-deoxyoctonate ammonium salt (CAS# 103404-70-2) is a ketosidic component in all lipopolysaccharides of Gram-negative bacteria and has been identified in several acidic exopolysaccharides (K-antigens). Synthetic analogues of KDO may be studied for their potential to disrupt the biosynthesis of bacterial cell-wall components, and lead to new antibacterial agents. Synonyms: azane;6-(1,2-dihydroxyethyl)-2,4,5-trihydroxyoxane-2-carboxylic acid. CAS No. 103404-70-2. Molecular formula: C8H17NO8. Mole weight: 255.22. | |
| 2-(tert-Butyl)-4-methoxyphenol | 2-tert-Butyl-4-methoxyphenol is a major component of Butylhydroxyanisole (BHA) (HY-B1066). 2-tert-Butyl-4-methoxyphenol is an antioxidant agent, that inhibits expression of Cox2 and Tnfa genes upon stimulation with Lipopolysaccharides (HY-D1056). 2-tert-Butyl-4-methoxyphenol exhibits anti-inflammatory activity, combined with 2,6-di-tert-butyl-4-methylphenol (BHT) [1]. Uses: Scientific research. Group: Natural products. CAS No. 121-00-6. Pack Sizes: 500 mg; 1 g. Product ID: HY-W010037. |  |
| 3',4',5,7-Tetra-O-benzylquercetin | 3',4',5,7-Tetra-O-benzylquercetin, is an related compound of the flavanoid Quercetin (Q509500) with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 116973-12-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C43H34O7. US Biological Life Sciences. | Worldwide |
| 3-Bodipy-propanoic acid | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: BDP FL carboxylic acid;4,4-Difluoro-5,7-dimethyl-3-(2-carboxyethyl)-4-bora-3a,4a-diaza-S-indacene; 7-(2-carboxyethyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; BDP FL acid; BODIPY FL. Grades: 95%. CAS No. 165599-63-3. Molecular formula: C14H15BF2N2O2. Mole weight: 292.093. | |
| 3-deoxy-8-phosphooctulonate synthase | This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. This enzyme participates in lipopolysaccharide biosynthesis. Group: Enzymes. Synonyms: 2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating); 2-dehydro-3-deoxy-phosphooctonate aldolase; 2-keto-3-deoxy-8-phosphooctonic synthetase; 3-deoxy-D-manno-octulosonate-8-phosphate synthase; 3-deoxy-D-mannooctulosonate-8-phosphate synthetase; 3-deoxyoctulosonic 8-phosphate synthetase; KDOP synthase; phospho-2-keto-3-deoxyoctonate aldolase. Enzyme Commission Number: EC 2.5.1.55. CAS No. 9026-96-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2792; 3-deoxy-8-phosphooctulonate synthase; EC 2.5.1.55; 9026-96-4; 2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating); 2-dehydro-3-deoxy-phosphooctonate aldolase; 2-keto-3-deoxy-8-phosphooctonic synthetase; 3-deoxy-D-manno-octulosonate-8-phosphate synthase; 3-deoxy-D-mannooctulosonate-8-phosphate synthetase; 3-deoxyoctulosonic 8-phosphate synthetase; KDOP synthase; phospho-2-keto-3-deoxyoctonate aldolase. Cat No: EXWM-2792. | |
| 3-deoxy-α-D-manno-octulosonate 8-oxidase | The enzyme, characterized from the bacterium Shewanella oneidensis, is involved in the formation of 8-amino-3,8-dideoxy-α-D-manno-octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. cf. EC 2.6.1.109, 8-amino-3,8-dideoxy-α-D-manno-octulosonate transaminase. Group: Enzymes. Synonyms: kdnB (gene name). Enzyme Commission Number: EC 1.1.3.48. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0421; 3-deoxy-α-D-manno-octulosonate 8-oxidase; EC 1.1.3.48; kdnB (gene name). Cat No: EXWM-0421. | |
| 3-deoxy-manno-octulosonate-8-phosphatase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase. This enzyme participates in lipopolysaccharide biosynthesis. Group: Enzymes. Enzyme Commission Number: EC 3.1.3.45. CAS No. 59088-24-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3649; 3-deoxy-manno-octulosonate-8-phosphatase; EC 3.1.3.45; 59088-24-3. Cat No: EXWM-3649. | |
| 3-deoxy-manno-octulosonate cytidylyltransferase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). This enzyme participates in lipopolysaccharide biosynthesis. Group: Enzymes. Synonyms: CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase; 2-keto-3-deoxyoctonate cytidylyltransferase; 3-Deoxy-D-manno-octulosonate cytidylyltransferase; CMP-3-deoxy-D-manno-octulosonate synthetase; CMP-KDO synthetase; CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase; cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase. Enzyme Commission Number: EC 2.7.7.38. CAS No. 37278-28-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3249; 3-deoxy-manno-octulosonate cytidylyltransferase; EC 2.7.7.38; 37278-28-7; CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase; 2-keto-3-deoxyoctonate cytidylyltransferase; 3-Deoxy-D-manno-octulosonate cytidylyltransferase; CMP-3-deoxy-D-manno-octulosonate synthetase; CMP-KDO synthetase; CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase; cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase. Cat No: EXWM-3249. | |
| 3-deoxyoctulosonase | Releases Kdo (α- and β-linked 3-deoxy-D-manno-octulosonic acid) from different lipopolysaccharides, including Re-LPS from Escherichia coli and Salmonella, Rd-LPS from S. minnesota, and de-O-acyl-re-LPS. 4-Methylumbelliferyl-α-Kdo (α-Kdo-OMec) is also a substrate. Group: Enzymes. Synonyms: α-Kdo-ase. Enzyme Commission Number: EC 3.2.1.144. CAS No. 199128-67-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3827; 3-deoxyoctulosonase; EC 3.2.1.144; 199128-67-1; α-Kdo-ase. Cat No: EXWM-3827. | |
| 3-O-Methyl Quercetin | A metabolite of the flavanoid Quercetin with inhibitory activity on lipopolysaccharide-induced activation of macrophage U937 cells. Group: Biochemicals. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-1-benzopyran-4-one; 3-Methoxy-3',4',5,7-tetrahydroxyflavone; 3-Methylquercetin; 3-Methylquercetol; 3',4',5,7-Tetrahydroxy-3-methoxyflavone; 5,7,3',4'-Tetrahydroxy-3-methoxyflavone; NSC 154016; Quercetin 3-Methyl Ether; Quercetin-3-O-methyl Ether. Grades: Highly Purified. CAS No. 1486-70-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 4-DAMP | 4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-DAMP methiodide. CAS No. 1952-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100958. | |
| 7α,27-Dihydroxycholesterol | 7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC); it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC). Uses: Scientific research. Group: Signaling pathways. CAS No. 4725-24-0. Pack Sizes: 1 mg. Product ID: HY-W414548. | |
| 8(4'-bromophenyl)-1,3,5,7-tetramethyl-BODIPY | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: 8-(4-Bromophenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene. CAS No. 850534-66-6. Molecular formula: C19H18BBrF2N2. Mole weight: 403.077. | |
| 8-amino-3,8-dideoxy-α-D-manno-octulosonate transaminase | The enzyme, characterized from the bacterium Shewanella oneidensis, forms 8-amino-3,8-dideoxy-α-D-manno-octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. cf. EC 1.1.3.48, 3-deoxy-α-D-manno-octulosonate 8-oxidase. Group: Enzymes. Synonyms: kdnA (gene name). Enzyme Commission Number: EC 2.6.1.109. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2849; 8-amino-3,8-dideoxy-α-D-manno-octulosonate transaminase; EC 2.6.1.109; kdnA (gene name). Cat No: EXWM-2849. | |
| AC 264613 | AC 264613 is a potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 7.5). AC 264613 inhibits interferon regulatory factor 5 and decreases interleukin-12p40 production via lipopolysaccharide-stimulated macrophages. PI hydrolysis, Ca2+ mobilization and cellular proliferation are activated by AC 264613 in vitro (pEC50 = 6.9, 7.0 and 7.5, respectively). Synonyms: AC-264613; AC 264613; AC264613; (±)-(3R,4S)-2-Oxo-4-phenyl-3-pyrollidinecarboxylic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide. Grades: ≥98% by HPLC. CAS No. 1051487-82-1. Molecular formula: C19H18BrN3O2. Mole weight: 400.27. | |
| acyloxyacyl hydrolase | The substrate is lipid A on the reducing end of the toxic lipopolysaccharide (LPS) of Salmonella typhimurium and related organisms. It consists of diglucosamine, β-D-GlcN-(1? 6)-D-GlcN, attached by glycosylation on O-6 of its non-reducing residue, phosphorylated on O-4 of this residue and on O-1 of its potentially reducing residue. Both residues carry 3-(acyloxy)acyl groups on N-2 and O-3. The enzyme from human leucocytes detoxifies the lipid by hydrolysing the secondary acyl groups from O-3 of the 3-hydroxyacyl groups on the disaccharide (LPS). It also possesses a wide range of phospholipase and acyltransferase activities [e.g. EC 3.1.1.4 (phospholipase A2), EC 3.1.1.5 (lysophospholipase), EC 3.1.1.32 (phospholipase A1) and EC 3.1.1.52 (phosphatidylinositol deacylase)], hydrolysing diacylglycerol and phosphatidyl compounds, but not triacylglycerols. It has a preference for saturated C12-C16 acyl groups. Group: Enzymes. Enzyme Commission Number: EC 3.1.1.77. CAS No. 110277-64-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3505; acyloxyacyl hydrolase; EC 3.1.1.77; 110277-64-0. Cat No: EXWM-3505. | |
| AG 126 - CAS 118409-62-4 | A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-? and nitric oxide in murine peritoneal macrophages. Group: Fluorescence/luminescence spectroscopy. | |
| Alexidine dihydrochloride | Alexidine dihydrochloride is a potent and selective protein tyrosine phosphatase localized to the mitochondrion 1(PTPMT1) inhibitor with IC50 value of 1.08 μM in vitro. It induces apoptosis in cancer cell lines with ED50 value of 1.8-2.6 μM. It is an alkyl bis(biguanide) antiseptic and has been used in mouthwashes to eliminate plaque forming microorganisms. It binds to lipopolysaccharide and lipoteichoic acid, and inhibits fungal phospholipase B with IC50 value of 250 nM. It stimulates increased insulin secretion by isolated rat pancreatic islets and displays antitcancer properties in FaDu cells. It has antibacterial, antiplaque properties against streptococcus mutans, actinomyces naesludii and actinomyces ciscosus. Synonyms: 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2); 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride; Biguanide, 1,1'-hexamethylenebis[5-(2-ethylhexyl)-, dihydrochloride; 1,6-Bis(2-ethylhexylbiguanido)hexane dihydrochloride; Alexidine hydrochloride; Hexamethylenebis(2-ethylhexyl)biguanide dihydrochloride. Grades: >98%. CAS No. 1715-30-6. Molecular formula: C26H58N10Cl2. Mole weight: 581.71. | |
| α-D-Mannose-1-phosphate ammonium salt | α-D-Mannose-1-phosphate ammonium salt, a valuable compound in biomedicine, has been employed for the examination and regulation of disorders concerning carbohydrate metabolism. The compound also exhibits noteworthy therapeutic effects on hepatic glycogen storage diseases, besides being an essential precursor for the synthesis of lipopolysaccharides and glycoproteins. Ongoing studies have been dedicated to the application of this compound, enhancing the horizons of biomedicine. Synonyms: ammonium (2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl phosphate; Diammonium 1-O-phosphonato-α-D-mannopyranose; α-D-Mannopyranose, 1-(dihydrogen phosphate), diammonium salt. Grades: ≥95%. CAS No. 1388225-12-4. Molecular formula: C6H19N2O9P. Mole weight: 294.20. | |
| Apremilast | Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase ( PDE-4 ) with an IC 50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC 50 of 104 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-10004. CAS No. 608141-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12085. | |
| arabinose-5-phosphate isomerase | The enzyme is involved in the pathway for synthesis of 3-deoxy-D-manno-octulosonate (Kdo), a component of bacterial lipopolysaccharides and plant call walls. Group: Enzymes. Synonyms: kdsD (gene name); gutQ (gene name); arabinose phosphate isomerase; phosphoarabinoisomerase; D-arabinose-5-phosphate ketol-isomerase. Enzyme Commission Number: EC 5.3.1.13. CAS No. 9023-86-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5454; arabinose-5-phosphate isomerase; EC 5.3.1.13; 9023-86-3; kdsD (gene name); gutQ (gene name); arabinose phosphate isomerase; phosphoarabinoisomerase; D-arabinose-5-phosphate ketol-isomerase. Cat No: EXWM-5454. | |
| AS1940477 | AS1940477 is p38 MAPK inhibitor. AS1940477 inhibited the enzymatic activity of recombinant p38α and β isoforms but showed no effect against other 100 protein kinases including p38γ and δ isoforms. In human peripheral blood mononuclear cells, AS1940477 inhibited lipopolysaccharide (LPS)- or phytohemagglutinin A (PHA)-induced production of proinflammatory cytokines, including TNFα, IL-1β, and IL-6 at low concentrations (LPS/TNFα, IC(50)=0.45n M; PHA/TNFα, IC(50)=0.40 nM). In addition, equivalent concentrations of AS1940477 that inhibited cytokine production also inhibited TNFα- and IL-1 β-induced production of IL-6, PGE(2), and MMP-3 in human synovial stromal cells. AS1940477 was also found to potently inhibit TNF production in whole blood (IC(50)=12 nM) and effectively inhibited TNFα production induced by systemically administered LPS in rats at less than 0.1mg/kg (ED(50)=0.053 mg/kg) with an anti-inflammatory effect lasting for 20h after oral administration. Overall, this study demonstrated that AS1940477 is a novel and potent p38 MAPK inhibitor and may be useful as a promising anti-inflammatory agent for treating inflammatory disorders. Synonyms: AS1940477; AS-1940477; AS 1940477. CAS No. 928344-12-1. Molecular formula: C24H22FN5O2. Mole weight: 431.47. | |
| Astacidin | Astacidin is an antimicrobial peptide produced by Procambarus clarkii (freshwater crayfish Pacifastacus leniusculus). It encodes a peptide of 43 amino acids, with a signal peptide of 23 amino acids. The mature peptide contains 20 amino acids, among which four are proline/arginine amino acids. The synthetic mature peptide has inhibitory effects on both Gram-positive and gram-negative bacteria and has the ability to bind bacterial cell wall components, including peptidoglycan, lipopolysaccharide and lipophoteicic acid. Synonyms: PcAst; Met-Arg-Leu-Leu-His-Leu-Leu-Leu-Ser-Val-Ala-Leu-Val-Ala-Leu-Met-Ala-Ala-Val-Pro-Ser-Gln-Ala-Ser-Asn-Gly-Tyr-Arg-Pro-Ala-Tyr-Arg-Pro-Ala-Tyr-Arg-Pro-Ser-Tyr-Arg-Pro-Gly-Lys. Grades: >98%. | |
| BDY FL, SE | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Synonyms: 3-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-7,9-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; 7-(3-((2,5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Propionic Acid, Succinimidyl Ester; BDP FL NHS ester. Grades: NMR 1H, HPLC-MS (95+%). CAS No. 146616-66-2. Molecular formula: C18H18BF2N3O4. Mole weight: 389.166. | |
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