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LL-37 (37-1), reverse LL-37, acts as a control peptide. Synonyms: Cationic Antimicrobial Protein 18 (170-134) (human); hCAP-18 (170-134); H-Ser-Glu-Thr-Arg-Pro-Val-Leu-Asn-Arg-Leu-Phe-Asp-Lys-Ile-Arg-Gln-Val-Ile-Arg-Lys-Phe-Glu-Lys-Gly-Ile-Lys-Glu-Lys-Ser-Lys-Arg-Phe-Phe-Asp-Gly-Leu-Leu-OH. Grades: ≥95%. CAS No. 2022972-70-7. Molecular formula: C205H340N60O53. Mole weight: 4493.33.
LL-37, acetylated, amidated
It is an antimicrobial peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. LL-37 has antimicrobial and anti-biofilm activity against a variety of Gram-positive and Gram-negative human pathogens, and has wound-healing effect on the host. Synonyms: Ac-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-NH2. Grades: ≥95%. Molecular formula: C207H343N61O53. Mole weight: 4534.30.
LL-37 amide
LL-37 amide, an antimicrobial peptide, has angiogenic activity. Synonyms: Antibacterial Protein LL-37 amide (human); H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-NH2; L-leucyl-L-leucyl-glycyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-lysyl-L-seryl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-glycyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-alpha-glutamyl-L-serinamide. Grades: ≥95% by HPLC. CAS No. 597562-32-8. Molecular formula: C205H341N61O52. Mole weight: 4492.29.
Ll-37-Derived Aurein 1.2 Analog
Ll-37-Derived Aurein 1.2 Analog is an antibacterial peptide. It has anti-human immunodeficiency virus type 1 activity. Synonyms: Arg-Leu-Phe-Asp-Lys-Ile-Arg-Gln-Val-Ile-Arg-Lys-Phe-NH2. Molecular formula: C80H136N26O16. Mole weight: 1718.13.
LL-37 FK-13
The core sequence of LL-37, FK-13, is protected from bacterial proteolysis by actin. FK-13 has inhibitory activity against HIV-1 with an EC50 of 3.4 μM. FKRIVQRIKDFLR corresponds to the minimal HIV resistance region of human LL-37 due to inactivation caused by N-terminal phenylalanine removal. Synonyms: LL-37 (17-29); Cationic Antimicrobial Protein 18 (150-162) (human); hCAP18 (150-162); H-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-OH; L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginine. Grades: ≥95%. CAS No. 717919-68-1. Molecular formula: C80H135N25O17. Mole weight: 1719.11.
LL-37 FKR
LL-37 FKR, a C-terminal fragment of LL-37, has antimicrobial activity and concentration-dependent chemotactic activity on granulocyte cells similar to the full-length peptide. Synonyms: LL-37 (17-37); FK-21; H-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; L-Phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparaginyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-α-glutamyl-L-serine; Cationic Antimicrobial Protein 18 (150-170) (human); hCAP-18 (150-170). Grades: ≥95%. CAS No. 913736-94-4. Molecular formula: C118H199N37O30. Mole weight: 2616.07.
LL-37 GKE
The antimicrobial activity of LL-37 GKE against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, and Candida parapsilosis is similar to or even stronger than that of full-length LL-37. Synonyms: Antimicrobial peptide GKE21; GK-21; H-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-OH; glycyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-arginine; LL-37 (14-34); hCAP-18 (147-167); Cationic Antimicrobial Protein 18 (147-167) (human). Grades: ≥95%. CAS No. 913736-92-2. Molecular formula: C119H202N38O28. Mole weight: 2613.15.
LL-37, human
LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 154947-66-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1222.
LL-37, Human
LL-37 is a cationic and α-helical antimicrobial peptide. It can inhibit growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner. LL-37 can promote wound healing following skin-targeted electroporation of a plasmid encoding hCAP-18/LL-37 in mice. Synonyms: LL 37; LL37; L-leucyl-L-leucyl-glycyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-lysyl-L-seryl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-glycyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-alpha-glutamyl-L-serine; H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; Cathelicidin; Bac4; Cap-18. Grades: 98%. CAS No. 154947-66-7. Molecular formula: C205H340N60O53. Mole weight: 4493.25.
LL-37, Human acetate
LL-37, Human acetate is a cationic and α-helical antimicrobial peptide. It can inhibit the growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner. LL-37 can promote wound healing following skin-targeted electroporation of a plasmid encoding hCAP-18/LL-37 in mice. Synonyms: L-Leucyl-L-leucylglycyl-L-α-aspartyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-lysyl-L-seryl-L-lysyl-L-α-glutamyl-L-lysyl-L-isoleucylglycyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparaginyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-α-glutamyl-L-serine acetate salt; H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH acetate salt; Cathelicidin LL 37 (human) acetate salt; Ropocamptide acetate salt. Grades: ≥95%. Molecular formula: C207H344N60O55. Mole weight: 4553.31.
LL-37, Human TFA
LL-37, Human TFA is a cationic and α-helical antimicrobial peptide. It can inhibit the growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner. It has wound-healing effect on the host. Synonyms: Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser.TFA; L-leucyl-L-leucyl-glycyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-lysyl-L-seryl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-glycyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-alpha-glutamyl-L-serine trifluoroacetic acid; Cathelicidin trifluoroacetic acid. Grades: ≥95%. Molecular formula: C205H340N60O53.C2HF3O2. Mole weight: 4607.28.
LL-37 KRI
LL-37 KRI is detected in human sweat and exhibits higher antimicrobial activity. It corresponds to LL-37 (18-37). Synonyms: LL-37 (18-37); H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; KR-20; L-Serine, L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparaginyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-α-glutamyl-; KR 20 (antimicrobial peptide). Grades: ≥95%. CAS No. 672333-78-7. Molecular formula: C109H190N36O29. Mole weight: 2468.93.
LL-37 pentamide is an antibacterial peptide, which has activity against gram-positive bacteria. Synonyms: Leu-Leu-Gly-Asn-Phe-Phe-Arg-Lys-Ser-Lys-Gln-Lys-Ile-Gly-Lys-Gln-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asn-Phe-Phe-Arg-Asn-Leu-Val-Pro-Arg-Thr-Gln-Ser. Grades: 97.1%. Molecular formula: C208H343N65O48. Mole weight: 4522.46.
LL-37 RKS
LL-37 fragments RK-31 and KR-20 with antimicrobial activity have been identified as physiological components of human sweat. Synonyms: LL-37 (7-37); H-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; Cationic Antimicrobial Protein 18 (140-170) (human); hCAP-18 (140-170); RK-31. Grades: ≥95%. CAS No. 672345-61-8. Molecular formula: C169H292N54O45. Mole weight: 3800.51.
LL-37 (scrambled)
LL-37 (scrambled) is the control peptide for LL-37. Synonyms: Cationic Antimicrobial Protein 18 (134-170) (Scrambled) (human); H-Gly-Leu-Lys-Leu-Arg-Phe-Glu-Phe-Ser-Lys-Ile-Lys-Gly-Glu-Phe-Leu-Lys-Thr-Pro-Glu-Val-Arg-Phe-Arg-Asp-Ile-Lys-Leu-Lys-Asp-Asn-Arg-Ile-Ser-Val-Gln-Arg-OH; hCAP-18 (134-170); glycyl-L-leucyl-L-lysyl-L-leucyl-L-arginyl-L-phenylalanyl-L-alpha-glutamyl-L-phenylalanyl-L-seryl-L-lysyl-L-isoleucyl-L-lysyl-glycyl-L-alpha-glutamyl-L-phenylalanyl-L-leucyl-L-lysyl-L-threonyl-L-prolyl-L-alpha-glutamyl-L-valyl-L-arginyl-L-phenylalanyl-L-arginyl-L-alpha-aspartyl-L-isoleucyl-L-lysyl-L-leucyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-arginyl-L-isoleucyl-L-seryl-L-valyl-L-glutaminyl-L-arginine. Grades: ≥95%. CAS No. 1354065-56-7. Molecular formula: C205H340N60O53. Mole weight: 4493.33.
LL-37 scrambled peptide
LL-37 scrambled peptide is a scrambled version of the antimicrobial peptide LL-37. It can be used as a negative control or research screening tool. Synonyms: Gly-Leu-Lys-Leu-Arg-Phe-Glu-Phe-Ser-Lys-Ile-Lys-Gly-Glu-Phe-Leu-Lys-Thr-Pro-Glu-Val-Arg-Phe-Arg-Asp-Ile-Lys-Leu-Lys-Asp-Asn-Arg-Ile-Ser-Val-Gln-Arg. Grades: ≥97% by HPLC. Molecular formula: C205H340N60O53. Mole weight: 4493.25.
LL-37 SKE
LL-37 SKE has anti-HIV-1 activity. Synonyms: LL-37 (9-29); SK-21; H-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-OH; L-Seryl-L-lysyl-L-α-glutamyl-L-lysyl-L-isoleucylglycyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginine; Cationic Antimicrobial Protein 18 (142-162) (human); hCAP-18 (142-162). Grades: ≥95%. CAS No. 1072128-56-3. Molecular formula: C119H204N36O30. Mole weight: 2619.15.
5-FAM-LL-37
5-FAM-LL-37 is FAM-labeled LL-37 (ab/em = 494/518 nm). LL-37 is an antimicrobial peptide with angiogenic activity. Synonyms: Fluorescein-5-carbonyl-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH. Grades: ≥95%. CAS No. 2243219-81-8. Molecular formula: C226H350N60O59. Mole weight: 4851.63.
Tide FluorTM 2-LL-37
Dye-labeled LL-37, excitation at 500 nm, emission at 527 nm. Tide FluorTM-2 has an excellent photostability and brightness, and its fluorescence is pH-insensitive. Synonyms: Tide FluorTM 2-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH. Grades: ≥90%. Molecular formula: C205H340N60O53 + dye. Mole weight: 4962.
Tide FluorTM 2-LL-37 (scrambled)
Dye-labeled, scrambled sequence of LL-37, excitation at 500 nm, emission at 527 nm. Tide FluorTM-2 has an excellent photostability and brightness, and its fluorescence is pH-insensitive. ''Scrambled'' means that it contains the same amino acids as LL-37, but in a different order. Synonyms: Tide FluorTM 2-Gly-Leu-Lys-Leu-Arg-Phe-Glu-Phe-Ser-Lys-Ile-Lys-Gly-Glu-Phe-Leu-Lys-Thr-Pro-Glu-Val-Arg-Phe-Arg-Asp-Ile-Lys-Leu-Lys-Asp-Asn-Arg-Ile-Ser-Val-Gln-Arg-OH. Grades: ≥90%. Molecular formula: C205H340N60O53 + dye. Mole weight: 4962.
Tyr-LL-37
Tyr-LL-37 is an analog of LL-37 for radioiodination. Synonyms: [Tyr133]-Cationic Antimicrobial Protein 18 (134-170) (human); H-Tyr-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; Tyr-hCAP-18 (134-170). Grades: ≥95%. CAS No. 2022972-74-1. Molecular formula: C214H349N61O55. Mole weight: 4656.42.
HmdSL-37 is an antimicrobial peptide produced by Hylobates sp. (Gibbon, Hylobates moloch). It has antibacterial activity. Synonyms: Antibacterial protein LL-37; Ser-Leu-Gly-Asn-Phe-Phe-Arg-Lys-Ala-Arg-Lys-Lys-Ile-Gly-Glu-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Gln-His-Leu-Ile-Pro-Arg-Thr-Glu-Ala. Grades: ≥96%.
KKL-40
KKL-40 is a small molecule inhibitor that targets the trans-transcription process and is effective against methicillin-sensitive and -resistant Staphylococcus aureus (S. aureus) as well as other Gram-positive pathogens including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. KKL-40 synergizes with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not synergize with other antibiotics such as daptomycin, kanamycin, or erythromycin. Trans-transcription is an extreme form of recoding, and KKL-40 inhibits trans-transcription but is nontoxic to HeLa cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865285-47-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116863.
KR-12
KR-12 is an antibacterial peptide. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: KR-12 (human); Antibacterial Protein LL-37 amide (human) (18-29); H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2. Grades: 95.6%. CAS No. 1218951-51-9. Molecular formula: C71H127N25O15. Mole weight: 1570.9.
LL13-37
LL13-37 is an antibacterial peptide isolated from Homo sapiens (Human sweat). It has activity against gram-positive bacteria, gram-negative bacteria, cancer and fungi. Synonyms: C-terminal fragment, LL-37; H-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-al. Grades: 96.8%. Molecular formula: C137H232N42O35. Mole weight: 3027.6.
Lugdunin
Lugdunin is an antibiotic peptide. Lugdunin inhibits bacteria by dissipating their membrane potential. Lugdunin is active against Gram-positive bacteria, such as S. aureus , and reduces S. aureus skin and nasal colonization. Lugdunin induces LL-37 and CXCL8/MIP-2 in human keratinocytes and mouse skin [1]. Uses: Scientific research. Group: Peptides. CAS No. 1989698-37-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P4200.
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