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Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Clerodol; Monogynol B; Fagarasterol. CAS No. 545-47-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0790.
Lupeol
Lupeol. Group: Biochemicals. Grades: Highly Purified. CAS No. 545-47-1. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C30H50O. US Biological Life Sciences.
Worldwide
Lupeol
Lupeol - Product ID: NST-10-174. Category: Triterpens. Alternative Names: Monogynol B, (+)-Lupeol, Clerodol, Fagarasterol, Lupenol, ?-Viscol. Purity: 98%. Test method: HPLC. CAS No. 545-47-1. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White powder. Molecular formula: C30H50O. Mole weight: 426.73. Storage: +2 +8 °C.
Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory , antibacterial , anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to infertility [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1617-68-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-126114.
lupeol benzoate
Cas No. 1617-69-2. Molecular formula: C37H54O2. Mole weight: 530.82.
Also forms some β-amyrin. The recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3β,20-diol with small amounts of β-amyrin, germanicol, taraxasterol and ψ-taraxasterol. See EC 4.2.1.128 (lupan-3β,20-diol synthase). Group: Enzymes. Synonyms: LUPI; BPW; RcLUS. Enzyme Commission Number: EC 5.4.99.41. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5583; lupeol synthase; EC 5.4.99.41; LUPI; BPW; RcLUS. Cat No: EXWM-5583.
2,2'-Ethylenedianiline
2,2'-Ethylenedianiline is used as a reagent to synthesize Oxcarbazepine (O869250), a broad-specturm, second-generation anticonvulsant drug that is used to treat partial and complex partial seizures in children and adults. 2,2'-Ethylenedianiline is also used as a reagent to prepare a series of triterpines (e.g. Lupeol [L474850]), compounds that have chemopreventative activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 34124-14-6. Pack Sizes: 1g, 5g. Molecular Formula: C14H16N2, Molecular Weight: 212.29. US Biological Life Sciences.
Worldwide
β-amyrin 28-monooxygenase
The enzyme, found in plants, is involved in the biosynthesis of oleanane-type triterpenoids, such as ginsenoside Ro. The enzyme from Medicago trunculata (CYP716A12) can also convert α-amyrin and lupeol to ursolic acid and betulinic acid, respectively. Group: Enzymes. Synonyms: CYP716A52v2; CYP716A12; β-amyrin 28-oxidase. Enzyme Commission Number: EC 1.14.13.201. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0803; β-amyrin 28-monooxygenase; EC 1.14.13.201; CYP716A52v2; CYP716A12; β-amyrin 28-oxidase. Cat No: EXWM-0803.
β-amyrin synthase
Some organism possess a monofunctional β-amyrin synthase, other have a multifunctional enzyme that also catalyses the synthesis of α-amyrin (EC 5.4.99.40) or lupeol (EC 5.4.99.41). Group: Enzymes. Synonyms: 2,3-oxidosqualene β-amyrin cyclase; AsbAS1; BPY; EtAS; GgbAS1; LjAMY1; MtAMY1; PNY; BgbAS. Enzyme Commission Number: EC 5.4.99.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5580; β-amyrin synthase; EC 5.4.99.39; 2,3-oxidosqualene β-amyrin cyclase; AsbAS1; BPY; EtAS; GgbAS1; LjAMY1; MtAMY1; PNY; BgbAS. Cat No: EXWM-5580.
The enzyme produces germanicol, β-amyrin and lupeol in the ratio 63:33:4. Group: Enzymes. Synonyms: RsM1; (S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming). Enzyme Commission Number: EC 5.4.99.34. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5575; germanicol synthase; EC 5.4.99.34; RsM1; (S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming). Cat No: EXWM-5575.
lupan-3β,20-diol synthase
The reaction occurs in the reverse direction. The recombinant enzyme from Arabidopsis thaliana gives a 1:1 mixture of lupeol and lupan-3β,20-diol with small amounts of β-amyrin, germanicol, taraxasterol and ψ-taraxasterol. See EC 5.4.99.41 (lupeol synthase). Group: Enzymes. Synonyms: LUP1 (gene name). Enzyme Commission Number: EC 4.2.1.128. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4969; lupan-3β,20-diol synthase; EC 4.2.1.128; LUP1 (gene name). Cat No: EXWM-4969.
taraxerol synthase
The enzyme gives taraxerol, β-amyrin and lupeol in the ratio 70:17:13. Group: Enzymes. Synonyms: RsM2; (S)-2,3-epoxysqualene mutase (cyclizing, taraxerol-forming). Enzyme Commission Number: EC 5.4.99.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5576; taraxerol synthase; EC 5.4.99.35; RsM2; (S)-2,3-epoxysqualene mutase (cyclizing, taraxerol-forming). Cat No: EXWM-5576.
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