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| Product | Description | |
|---|---|---|
| MAOS | MAOS is a modified Trinders reagent that can be used as a chromogenic probe for the determination of H 2 O 2. MAOS is strongly dependent on the pH of the reaction medium [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 82692-97-5. Pack Sizes: 100 mg; 250 mg. Product ID: HY-15923. |  |
| MAOS | MAOS is a modified Trinder's reagent used in hydrogen peroxide determination. Synonyms: 3-[(3,5-Dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonic Acid Sodium Salt; Sodium 3-[(3,5-dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonate; N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline Sodium Salt. Grades: ≥95%. CAS No. 82692-97-5. Molecular formula: C13H20NNaO4S. Mole weight: 309.36. |  |
| Maltose alternan oligosaccharide | Maltose alternan oligosaccharide is a biomedical product used to study various health condition such as diabetes. Additionally, research suggests that it may have antioxidant and anti-inflammatory properties, making it useful in studying oxidative stress-related diseases. Synonyms: MAOS. | |
| N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline sodium salt monohydrate | N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline sodium salt monohydrate. Group: Biochemicals. Alternative Names: MAOS. Grades: Highly Purified. CAS No. 82692-97-5. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C13H22NNaO5S. US Biological Life Sciences. |  Worldwide |
| 1,4-Naphthoquinone | 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130-15-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W015490. | |
| 1,5-Naphthyridine-3-carbaldehyde | 1,5-Naphthyridine-3-carbaldehyde. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,5-Naphthyridine-3-carbaldehyde, 959617-49-3, AC1Q6PVZ, SCHEMBL1289832, CTK5H8470, DTXSID50678410, MAOABMVKXVXKFA-UHFFFAOYSA-N, 1,5-Naphthyridine-3-carboxaldehyde, 4506AF, KM3404, MFCD17171334, ZINC66054279, AKOS015854773, AK257863, DA-18832, HE266392, TR-038588, FT-0682868, I14-30239. Product Category: Heterocyclic Organic Compound. CAS No. 959617-49-3. Molecular formula: C9H6N2O. Mole weight: 158.16. Purity: 0.96. IUPACName: 1,5-naphthyridine-3-carbaldehyde. Canonical SMILES: C1=CC2=C(C=C(C=N2)C=O)N=C1. Product ID: ACM959617493. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 1-Bromo-3-phenylpropane | 1-Bromo-3-phenylpropane is used in the synthesis of MraY natural inhibitors as antibacterial agents. Also used in the preparation of quinolinone derivatives as potent and selective MAO-B inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 637-59-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H11Br, Molecular Weight: 199.09. US Biological Life Sciences. | Worldwide |
| (2, 2'-Bis (2-indenyl) biphenyl) zirconium Dichloride | (2, 2'-Bis (2-indenyl) biphenyl) zirconium Dichloride forms a metallocene and co-catalyst system with methylaluminoxane (MAO). It is also derived from 1,1-Diphenyl (D486980), which is a polycyclic aromatic hydrocarbon (PAH) that has been shown to cause genetic effects in yeast and developmental defects and mitotic abnormalities in sea urchins. Group: Biochemicals. Grades: Highly Purified. CAS No. 312968-31-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C30H20Cl2Zr, Molecular Weight: 542.61. US Biological Life Sciences. | Worldwide |
| (2-Bromoethyl-1,1,2,2-d4)-benzene | (2-Bromoethyl-1,1,2,2-d4)-benzene is an intermediate used in the synthesis of Phenelzine-d4 Sulfate (P295902), which is a labeled hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidepressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 1204688-07-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H5D4Br, Molecular Weight: 189.09. US Biological Life Sciences. | Worldwide |
| (2E)-1-(5-Bromo-2-thienyl)-3-[4-(dimethylamino)phenyl]-2-propen-1-one | (2E)-1-(5-Bromo-2-thienyl)-3-[4-(dimethylamino)phenyl]-2-propen-1-one is a monoamine oxidase B (MAO-B) inhibitor. Monoamine oxidase B is involved in the metabolism of dopamine. Mao-B inhibitors are potential compounds used to treat Parkinson's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 948841-07-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H14BrNOS, Molecular Weight: 336.25. US Biological Life Sciences. | Worldwide |
| 3- (Pentylamino) propanenitrile | 3- (Pentylamino) propanenitrile is a substrate and time-dependent irreversible inactivator of monoamine oxidase B (MAO B). Group: Biochemicals. Grades: Highly Purified. CAS No. 59676-91-4. Pack Sizes: 500mg, 2.5 g. Molecular Formula: C8H16N2, Molecular Weight: 140.229999999999. US Biological Life Sciences. | Worldwide |
| 4-methylaminobutanoate oxidase (methylamine-forming) | The enzyme participates in the nicotine degradation pathway of the soil bacterium Arthrobacter nicotinovorans. Has a very weak monoamine oxidase (EC 1.4.3.4) activity with 4-aminobutanoate. Group: Enzymes. Synonyms: mao (gene name, ambiguous). Enzyme Commission Number: EC 1.5.3.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1549; 4-methylaminobutanoate oxidase (methylamine-forming); EC 1.5.3.21; mao (gene name, ambiguous). Cat No: EXWM-1549. |  |
| 5-[[Methyl(2-propyn-1-yl)amino]methyl]-8-quinolinol Dihydrochloride | M 30 dihydrochloride is a potent and brain selective inhibitor of monoamine oxidase (MAO) with EC50 values of 37 and 57 nM for MAO-A and MAO-B, respectively. M 30 decreases cell death rates and apoptotic DNA damage, exhibiting neuroprtective properties. Synonyms: 5-[[methyl(prop-2-ynyl)amino]methyl]-8-quinolinol;dihydrochloride; 5-[[methyl(prop-2-ynyl)amino]methyl]quinolin-8-ol;dihydrochloride. Grades: ≥ 98 % by HPLC. CAS No. 64821-19-8. Molecular formula: C14H16Cl2N2O. Mole weight: 299.20. | |
| 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone | 7- Hydroxy- 3, 4- dihydro- 2(1H) - quinolinone (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone) is a weak MAO-A inhibitor, with an IC 50 of 183 μM, and has no effect on MAO-B [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone. CAS No. 22246-18-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W010130. | |
| 8-(3-Chlorostyryl)caffeine | 8-(3-Chlorostyryl)caffeine is a selective Adenosine A2A-R and MAO-B inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 147700-11-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H15ClN4O2, Molecular Weight: 330.77. US Biological Life Sciences. | Worldwide |
| Afobazole | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346; Afobazol; Fabomotizole; CM 346; CM-346. Grades: >98%. CAS No. 173352-21-1. Molecular formula: C15H21N3O2S. Mole weight: 307.41. | |
| Afobazole hydrochloride | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346 hydrochloride; Afobazol hydrochloride; Fabomotizole hydrochloride; CM 346 hydrochloride; CM-346 hydrochloride. Grades: >98%. CAS No. 173352-39-1. Molecular formula: C15H22ClN3O2S. Mole weight: 343.87. | |
| Anti-MAOB antibody produced in goat | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Anti-Metabolism Disease Compound Library | A unique collection of 1558 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or NMPA; - Covers various major targets including CYP, FAAH, IDO, MAO, etc. , in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc. ; Effective tool for cell metabolism research; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5200. Categories: Anti-Metabolism Disease Compounds Libraries. |  |
| Anti-Parkinson's Disease Compound Library | A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS. - Targets include Dopamine Receptor, COMT, MAO-B, 5-HT Receptor, etc. - Some of them are FDA approved. - Structurally diverse, medicinally active, and cell permeable; - Detailed information about compound structure, target, activity, IC50, etc. - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9830. Categories: Anti-Parkinson's Disease Compounds Libraries. | |
| ASS234 | ASS234 is a potent monoamino oxidase (MAO) inhibitor with IC 50 s of 5.2 nM and 43 nM for MAO-A and MAO-B, respectively. ASS234 also inhibits AChE and BuChE with IC 50 s of 350 nM and 460 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334106-34-1. Pack Sizes: 5 mg. Product ID: HY-121072. | |
| Benzeneethan-α,α, β, β-d4-ol | Benzeneethan-α,α, β, β-d4-ol is an intermediate used in the synthesis of Phenelzine-d4 Sulfate (P595902), which is a labeled hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidepressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 107473-33-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C8H6D4O, Molecular Weight: 126.19. US Biological Life Sciences. | Worldwide |
| Bifemelane hydrochloride | Bifemelane hydrochloride is a MAO inhibitor displaying antidepressant activity. Bifemelane reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets. Bifemelane has the potential to treat cerebral infarction and Alzheimer's disease for its neuroprotective and nootropic effects. Uses: Antidepressant. Synonyms: Celeport; Alnert; 4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride. Grades: ≥99% by HPLC. CAS No. 62232-46-6. Molecular formula: C18H23NO.HCl. Mole weight: 305.84. | |
| Bifemelane hydrochloride | Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive inhibitor of monoamine oxidase A (MAO-A) , with a K i of 4.20 μM. Bifemelane hydrochloride also inhibits MAO-B noncompetitively with a K i of 46.0 μM. Bifemelane hydrochloride has a potent antidepressant activity and can be used for the research of cognitive and emotional disturbances related to cerebrovascular disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-2016. CAS No. 62232-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1558A. | |
| Bizine | Lysine-specific demethylase 1 (LSD1) is an epigenetic enzyme, which can oxidatively cleave methyl groups from monomethyl and dimethyl Lys4 of histone H3. Bizine is an LSD1 inhibitor, which is a phenelzine analog that inhibits lysine-specific demethylase 1 with ki of 59 nM. It is 23-fold, 63-fold, and >100-fold selective for LSD-1 over monoamine oxidase (MAO) A, MAOB, and LSD2, respectively. Synonyms: BSM-0353. Grades: ≥95%. CAS No. 1591932-50-1. Molecular formula: C18H23N3O. Mole weight: 297.4. | |
| Brofaromine | Brofaromine (CGP 11305A) is a monoamine oxidase ( MAO ) inhibitor with IC 50 of 0.2?μM for MAO-A. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 11305A. CAS No. 63638-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13339. | |
| CAY10680 | The monoamine oxidases A and B are the products of two abutting X-linked genes, and play an important role in the metabolism of biogenic amines in the central nervous system. Inhibition of MAO-B is considered as a strategy to treat Parkinson's disease. CAY10680 is a benzothiazinone compound that selectively inhibits MAO-B with IC50 = 34.9 nM in human. The blockade of adenosine A2A receptors has emerged as a potential treatment for Parkinson's disease. CAY10680 has been shown to abolish cAMP accumulation in CHO cells transfected with adenosine A2A receptors. It can selectively inhibits with Ki of 39.5 nM in human. Synonyms: CAY 10680; CAY-10680. Grades: ≥98%. CAS No. 1439488-21-7. Molecular formula: C18H16N2O2S. Mole weight: 324.4. | |
| Chlorphenesin carbamate | Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant, as well as a derivate of Chlorphenesin (HY-A0133). Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation [1]. Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels [2]. Antinociceptive effect [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Maolate; U 19646. CAS No. 886-74-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107944. | |
| Cinnamylamine Hydrochloride | Cinnamylamine Hydrochloride, can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 5586-89-0. Pack Sizes: 25mg, 100mg. Molecular Formula: C9H12ClN, Molecular Weight: 169.65. US Biological Life Sciences. | Worldwide |
| Clorgyline hydrochloride | Clorgyline is a potent monoamine oxidase (MAO) inhibitor that preferentially targets MAO-A over MAO-B (Kis = 0.054 and 58 μM, respectively). This inhibition is irreversible. Clorgyline is without effect on serotonin receptors, but it does inhibit the sigma receptor σ1 on Jurkat human T lymphocyte cells (IC50 = 31 nM). Synonyms: N-2,4-Dichlorophenoxypropyl-N-methylpropargylamine. Grades: ≥98%. CAS No. 17780-75-5. Molecular formula: C13H15Cl2NO·HCl. Mole weight: 308.6. | |
| Contezolid | Contezolid (MRX-I), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid (MRX-I) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MRX-I. CAS No. 1112968-42-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19915. | |
| CP-409092 | CP-409092 is a GABA(A) partial agonist developed for the treatment of General Anxiety Disorder (GAD) and presents an interesting phenomenon of human pharmacokinetic predictions. In vitro, CP-409092 was abroadly metabolized in rat and human systems predominantly to acid metabolite formed by oxidative deamination of the N-methyl group of CP-409092 mediated by MAO-A (as deduced from inhibition experiments). Synonyms: N-[4-(methylaminomethyl)phenyl]-4-oxo-1,5,6,7-tetrahydroindole-3-carboxamide; 4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylic acid (4-methylaminomethylphenyl)amide; CP 409,092; CP 409092; CP-409,092; CP-409092; CP409,092; CP409092. Grades: >98%. CAS No. 194098-25-4. Molecular formula: C17H19N3O2. Mole weight: 297.35. | |
| enoyl-CoA hydratase 2 | This enzyme catalyses a hydration step in peroxisomal β-oxidation. The human multifunctional enzyme type 2 (MFE-2) is a 79000 Da enzyme composed of three functional units: (3R)-hydroxyacyl-CoA dehydrogenase, 2-enoyl-CoA hydratase 2 and sterol carrier protein 2-like units. The enzymes from Aeromonas caviae and Arabidopsis thaliana are monofunctional enzymes. 2-Enoyl-CoA hydratase 3 from Candida tropicalis is a part from multifunctional enzyme type 2. Group: Enzymes. Synonyms: 2-enoyl-CoA hydratase 2; AtECH2; ECH2; MaoC; MFE-2; PhaJAc; D-3-hydroxyacyl-CoA hydro-lyase; D-specific 2-trans-enoyl-CoA hydratase. Enzyme Commission Number: EC 4.2.1.119. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4959; enoyl-CoA hydratase 2; EC 4.2.1.119; 2-enoyl-CoA hydratase 2; AtECH2; ECH2; MaoC; MFE-2; PhaJAc; D-3-hydroxyacyl-CoA hydro-lyase; D-specific 2-trans-enoyl-CoA hydratase. Cat No: EXWM-4959. | |
| Entacapone | Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC 50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC 50 s>50 μM). Entacapone can be used for the research of Parkinson's disease [1]. Entacapone serves as a inhibitor of FTO demethylation with an IC 50 of 3.5 μM, can be used for the research of metabolic disorders [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130929-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14280. | |
| Eprobemide | Eprobemide is a reversible monoamine oxidase A (MAO-A) inhibitor and can be used as an antidepressant. Synonyms: LIS 630. Grades: 98%. CAS No. 87940-60-1. Molecular formula: C14H19ClN2O2. Mole weight: 282.769. | |
| Fabomotizole | Fabomotizole (CM346) is an insecticide with anxiolytic, antianxiety, and neuroprotective activities and a substrate of p-glycoprotein. Fabomotizole inhibits the ST-segment depression induced by isoproterenol in a rat model of acute subendocardial ischemia. Fabomotizole also inhibits Giardia lamblia and has the potential to inhibit giardiasis. Fabomotizole also targets Sigma1R , NRH:quinone reductase 2 (NQO2) , and MAO-A to exert anxiolytic effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM346. CAS No. 173352-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-14895. | |
| Furazolidone | Furazolidone is a monoamine oxidase (MAO) inhibitor with antiproliferative, apoptosis-inducing and differentiation-promoting activities. Furazolidone may inhibit leukemia fusion protein-mediated bone marrow transformation by upregulating the stability of the tumor suppressor protein p53. Furazolidone exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines and can be used for anti-AML research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-45-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1336. | |
| GSK-LSD1 2HCl | GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B). Synonyms: GSK LSD1 2HCl; GSK-LSD1 Dihydrochloride. Grades: >98%. CAS No. 1431368-48-7. Molecular formula: C14H22Cl2N2. Mole weight: 289.24. | |
| Harmane | Harmane is a benzodiazepine receptor inhibitor ( IC 50 =7 μM), with IC 50 values for mACh , Opioid Receptor , MAO-A/B , and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane inhibits the I1 imidazoline receptor ( IC 50 = 30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 486-84-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-101392. | |
| Hydralazine-D4 Hydrochloride | Hydralazine-D4 Hydrochloride is the labeled version of Hydralazine Hydrochloride (H716531), which is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes (1,2,3). It is also a non-selective MAO-A/B inhibitor and a semicarbazide-sensitive amine oxidase inhibitor and antihypertensive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H4D4N4; HCl, Molecular Weight: 164.203645999999. US Biological Life Sciences. | Worldwide |
| Hydralazine Hydrochloride | Hydralazine is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes. Non-selective MAO-A/B inhibitor; semicarbazide-sensitive amine oxidase inhibitor. Antihypertensive. Group: Biochemicals. Alternative Names: 1-Hydrazinylphthalazine Hydrochloride; 1(2H)-Phthalazinone Hydrazone Hydrochloride; 1-Phthalazinylhydrazine Hydrochloride; Apresoline Hydrochloride; Apulon; Hydralazine Chloride; Hydralazine Monohydrochloride; Lopres. Grades: Highly Purified. CAS No. 304-20-1. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| Hydroxylamine hydrochloride | Hydroxylamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of organic synthesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5470-11-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-Y0882. | |
| Hypericin | Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase , reverse transcriptase , telomerase and CYP ( cytochrome P450 ). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 548-04-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0453. | |
| Hypericin | Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Anthroquinone. Product Category: Inhibitors. Appearance: Powder. CAS No. 548-04-9. Molecular formula: C30H16O8. Mole weight: 504.44. Purity: 0.98. Canonical SMILES: CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O. Product ID: ACM548049. Alfa Chemistry ISO 9001:2015 Certified. | |
| Hypericin (Standard) | Hypericin (Standard) is the analytical standard of Hypericin. This product is intended for research and analytical applications. Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase , reverse transcriptase , telomerase and CYP ( cytochrome P450 ). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 548-04-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0453R. | |
| Indantadol | Indantadol is a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain. Synonyms: 2-(2,3-dihydro-1H-inden-2-ylamino)acetamide; CHF-3381; CNP-3381; GT-3381; V-3381; CMP-3381; CHF 3381; CNP 3381; GT 3381; V 3381; CMP 3381; CHF3381; CNP3381; GT3381; V3381; CMP3381; N-(2-indanyl)glycinamide; N-(2-indanyl)glycinamide hydrochloride. Grades: >98%. CAS No. 202844-10-8. Molecular formula: C11H14N2O. Mole weight: 190.246. | |
| Iproniazid | Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid has antidepressive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-92-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0886A. | |
| Iproniazid phosphate | Iproniazid phosphate is a non-selective, irreversible inhibitor of monoamine oxidase (MAOI) that has potential to treat hypertension. Synonyms: phosphoric acid;N'-propan-2-ylpyridine-4-carbohydrazide Iproniazid phosphate 305-33-9 Iproniazide phosphate Marsilid phosphate Isoproniazid phosphate Iproniazid as phosphate N'-Isopropylisonicotinohydrazide phosphate Iproniazid dihydrogen phosphate Iproni. CAS No. 305-33-9. Molecular formula: C9H16N3O5P. Mole weight: 277.21. | |
| Iproniazid phosphate | Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305-33-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0886. | |
| Isatin | Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC 50 of 3 μM. Also binds to central benzodiazepine receptors (IC 50 against clonazepam, 123 μM) [1]. Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity [2]. Shows effect on the serotonergic system [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Indoline-2,3-dione. CAS No. 91-56-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0265. | |
| Isatin | Isatin is an indole derivative used as an intermediate. It also acts as an endogenous MAO inhibitor with an IC50 value of 15 μM. Synonyms: 1H-indole-2,3-dione. CAS No. 91-56-5. Molecular formula: C8H5NO2. Mole weight: 147.13. | |
| Isocarboxazid | Isocarboxazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) belonging to the hydrazine class. It is primarily used to treat mood and anxiety disorders. It is also used for the treatment of Parkinson's disease and other dementia-related disorders. It is also effective in the treatment of major depression, dysthymic disorder, and atypical depression. It blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO, thereby increasing the concentrations of norepinephrine and 5-hydroxytrytamine at central aminergic receptors. It was developed by Validus and has been listed. Uses: Isocarboxazid is primarily used to treat mood and anxiety disorders. it is also used for the treatment of parkinson's disease and other dementia-related disorders. it is also effective in the treatment of major depression, dysthymic disorder, and atypical. Synonyms: 1-Benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine;3-Isoxazolecarboxylic acid, 5-methyl-, 2-(phenylmethyl)hydrazide;3-Isoxazolecarboxylic acid, 5-methyl-, 2-benzylhydrazide;5-Methyl-3-isoxazole-carboxylic Acid 2-Benzylhydrazide;3-(N-Benzylhydrazinocarbon. Grades: 95%. CAS No. 59-63-2. Molecular formula: C12H13N3O2. Mole weight: 231.25. | |
| J147 | J147 is an exceptionally potent, orally active, neuroprotective agent for cognitive enhancement. J147 can pass the blood brain barrier (BBB). J147 can inhibit monoamine oxidase B ( MAO B ) and the dopamine transporter. J147 plays an impotant role in Alzheimers disease (AD) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807913-16-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-13779A. | |
| Ladostigil | Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer's disease. Ladostigil is a dual acetylcholine-butyrylcholineesterase and brain selective monoamine oxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine). Synonyms: [(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate; (N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate; Ladostigil; TV 3326; TV3326; TV-3326. Grades: >98%. CAS No. 209394-27-4. Molecular formula: C16H20N2O2. Mole weight: 272.348. | |
| Ladostigil hydrochloride | Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) , with IC 50 s of 37.1 and 31.8 μM for MAO-B and AChE , respectively. Ladostigil hydrochloride exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil can be used for the research of depression and Alzheimer's disease [1] [2]. Ladostigil (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TV-3326 hydrochloride. CAS No. 209394-18-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10399A. | |
| Ladostigil tartrate | Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer's disease. Ladostigil is a dual acetylcholine-butyrylcholineesterase and brain selective monoamine oxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine). Uses: A novel brain-selective mao inhibitor, ladostigil can selectively reverse the behavioral and neurochemical effects induced by prenatal stress without affecting the behavior of controls. antidepressant. Synonyms: ethylmethyl-carbamic acid (3r)-2,3-dihydro-3-(2-propynylamino)-1h-inden-5-yl ester (2r,3r)-2,3-dihydroxybutanedioate (2:1); ladostigil tartrate; Ethylmethyl-carbamic acid (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester (2R,3R)-2,3-dihydroxybutaned. Grades: >98%. CAS No. 209394-46-7. Molecular formula: 2(C16H20N2O2).C4H6O6. Mole weight: 694.78. | |
| Ladostigil Tartrate | Multifunctional drug designed to treat Alzhemier?s disease by combining in a single molecule the neuroprotective / neurorestorative effects of the (MAO)-B inhibitor rasagiline with the cholinesterase (ChE) inhibitory activity of rivastigmine. Group: Biochemicals. Alternative Names: N-Ethyl-N-methylcarbamic Acid (3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-5-yl Ester (2R,3R)-2,3-Dihydroxybutanedioate; TV 3326. Grades: Highly Purified. CAS No. 209394-46-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H23N2O5, Molecular Weight: 347.39. US Biological Life Sciences. | Worldwide |
| Lazabemide hydrochloride | Lazabemide is a monoamine oxidase B inhibitor with IC50 values of 0.03 and > 100 μM for MAO-B and MAO-A. It is potentially an antiparkinsonian agent. Uses: Antiparkinson agents. Synonyms: N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 103878-83-7. Molecular formula: C8H10ClN3O.HCl. Mole weight: 236.1. | |
| LSD1/HDAC6-IN-2 | LSD1/HDAC6-IN-2 (JBI-802) is an orally active LSD1 / HDAC6 / MAO-A inhibitor, with IC 50 values of 5 nM, 11 nM, and 5 nM, respectively. LSD1/HDAC6-IN-2 can inhibit the growth of multiple myeloma cells MM.1S, MM.1R, and RPMI-8226. LSD1/HDAC6-IN-2 can be used for research on diseases such as acute myeloid leukemia and lymphoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2982787-50-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164099. | |
| LSD1 Inhibitor IV, RN-1,HCl (2- (1R, 2S) -2- (4- (Benzyloxy) phenyl) cyclopropylamino) -1- (4-methylpiperazin-1-yl) ethanone, HCl, Lysine (K)-Specific Demethylase Inhibitor IV,RN-1,HCl, BHC110 Inhibitor IV, KDM1 Inhibitor IV, MOA Inhibitor III) | A cell-permeable tranylcypromine (parnate) analog that acts as a potent, irreversible inhibitor of lysine specific demethylase 1 (LSD1; IC50=70nM in a HRP-coupled assay using H3K4Me2 peptide substrate). Forms a covalent adduct with flavin adenine dinucleotide (FAD). Shown to cross the blood brain barrier. Exhibits moderate selectivity over amine oxidases MAO-A and MAO-B (IC50=0.51 and 2.785uM, respectively). Displays desirable pharmacokinetic properties (brain/plasma exposure ratio of 88.9), and impairs long-term memory without affecting short-term memory in mice (10mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MAO-A inhibitor 1 | MAO-A inhibitor 1 (compound VIII) is a MAO-A inhibitor, with an IC 50 of 100 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 119229-96-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N12485. | |
| Maoecrystal A | Maoecrystal A. Group: Biochemicals. Grades: Plant Grade. CAS No. 96850-30-5. Pack Sizes: 10mg. Molecular Formula: C22H28O6, Molecular Weight: 388.45. US Biological Life Sciences. | Worldwide |
| MAO-IN-1 | An inhibitor of monoamine oxidase B (MAO B) (IC50= 20 nM). Synonyms: (2S)-1-[4-[(3-chlorophenyl)methoxy]phenoxy]-3-methoxypropan-2-ol. CAS No. 124991-40-8. Molecular formula: C17H19ClO4. Mole weight: 322.78. | |
| MDL-72274 HCl | MDL-72274 is a selective SSAO inhibitor. It is a potent (IC50 = 10(-9) M) inhibitor of both MAO-B and SSAO, with 190-fold lower affinity for MAO-A. MDL-72974 can be used for the treatment of Parkinson diseases. Uses: Parkinson diseases. Synonyms: MDL72274; MDL-72274; MDL 72274; MDL72274A; MDL-72274A; MDL 72274A; MDL72274 HCl; (E)-3-chloro-2-phenylprop-2-en-1-amine hydrochloride. Grades: 98%. CAS No. 85278-24-6. Molecular formula: C9H11Cl2N. Mole weight: 204.09. | |
| Metaxalone | Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHR438; NSC170959. CAS No. 1665-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0678. | |
| Methyl citrate | Methyl citrate is a Monoamine oxidase B ( MAO-B ) inhibitor ( IC 50 =0.23 mM). Methyl citrate is isolated from the fruits of Opuntia ficus-indica var. saboten Makino [1]. Uses: Scientific research. Group: Natural products. CAS No. 26163-61-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N9540. | |
| Methylene Blue | Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC) , monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Basic Blue 9; CI-52015; Methylthioninium chloride. CAS No. 61-73-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-14536. | |
| Methylene blue hydrate | Methylene blue (Basic Blue 9) hydrate is a guanylyl cyclase (sGC) , monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue hydrate through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue hydrate is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Basic Blue 9 hydrate; CI-52015 hydrate; Methylthioninium chloride hydrate. CAS No. 122965-43-9. Pack Sizes: 1 g; 5 g. Product ID: HY-D0958. | |
| Methylene blue hydrate | Methylene blue (Basic Blue 9) hydrate is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue hydrate through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue hydrate is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 122965-43-9. Molecular formula: C16H18ClN3S.xH2O. Mole weight: 337.87. Canonical SMILES: CN(C1=CC2=[S+]C3=C(C=CC(N(C)C)=C3)N=C2C=C1)C.[x].[Cl-].O. Product ID: ACM122965439. Alfa Chemistry ISO 9001:2015 Certified. Categories: [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;hydrate. | |
| Methylene blue trihydrate | Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC) , monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C.I. Basic Blue 9 trihydrate. CAS No. 7220-79-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1359. | |
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