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| Product | Description | |
|---|---|---|
| Medicarpin | Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of agents [1]. Uses: Scientific research. Group: Natural products. CAS No. 32383-76-9. Pack Sizes: 5 mg. Product ID: HY-N3308. |  |
| Medicarpin | Medicarpin isolated from the herb of Hedysarum polybotrys Hand. -Mazz. It stimulates osteoblast differentiation via ERβ, and promotes achievement of peak bone mass. Uses: Potential osteogenic agent. Synonyms: 3-HYDROXY-9-METHOXYPTEROCARPAN; [6aR,11aR,(-)]-6a,11a-Dihydro-9-methoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol. Grade: 0.99. CAS No. 32383-76-9. Molecular formula: C16H14O4. Mole weight: 270.3. |  |
| medicarpin synthase | Isolated from the plant Medicago sativa (alfalfa). Catalyses the final step in the biosynthesis of medicarpin, the main pterocarpan phytoalexin in alfalfa. Group: Enzymes. Synonyms: medicarpan synthase; 7,2'-dihydroxy-4'-methoxyisoflavanol dehydratase; 2',7-dihydroxy-4'-methoxyisoflavanol dehydratase; DMI dehydratase; DMID. Enzyme Commission Number: EC 4.2.1.139. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4980; medicarpin synthase; EC 4.2.1.139; medicarpan synthase; 7,2'-dihydroxy-4'-methoxyisoflavanol dehydratase; 2',7-dihydroxy-4'-methoxyisoflavanol dehydratase; DMI dehydratase; DMID. Cat No: EXWM-4980. |  |
| (+)-Medicarpin | (+)-Medicarpin, a pterocarpan, is an isoflavonoid isolated from several medicinal plant species with a variety of biological effects, including Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, and so on. It can effectively inhibit osteoclastogenesis, promote bone healing and increase bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action. Synonyms: (6aS,11aS)-Medicarpin; (6aS,11aS)-Demethylhomopterocarpin; 6H-Benzofuro[3,2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, cis-. CAS No. 33983-39-0. Molecular formula: C16H14O4. Mole weight: 270.28. | |
| 2'-hydroxyisoflavone reductase | In the reverse reaction, a 2'-hydroxyisoflavone is reduced to an isoflavanone; 2'-hydroxypseudobaptigenin also acts. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. Group: Enzymes. Synonyms: NADPH:2'-hydroxyisoflavone oxidoreductase; isoflavone reductase; 2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase. Enzyme Commission Number: EC 1.3.1.45. CAS No. 128449-69-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1317; 2'-hydroxyisoflavone reductase; EC 1.3.1.45; 128449-69-4; NADPH:2'-hydroxyisoflavone oxidoreductase; isoflavone reductase; 2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase. Cat No: EXWM-1317. | |
| 4'-methoxyisoflavone 2'-hydroxylase | A heme-thiolate protein (P-450). Acts on isoflavones with a 4'-methoxy group, such as formononetin and biochanin A. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. EC 1.14.13.89, isoflavone 2'-hydroxylase, is less specific and acts on other isoflavones as well as 4'-methoxyisoflavones. Group: Enzymes. Synonyms: isoflavone 2'-monooxygenase (ambiguous); isoflavone 2'-hydroxylase (ambiguous). Enzyme Commission Number: EC 1.14.13.53. CAS No. 110183-49-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0860; 4'-methoxyisoflavone 2'-hydroxylase; EC 1.14.13.53; 110183-49-8; isoflavone 2'-monooxygenase (ambiguous); isoflavone 2'-hydroxylase (ambiguous). Cat No: EXWM-0860. | |
| isoflavone 3'-hydroxylase | A heme-thiolate protein (P-450). Also acts on biochanin A and other isoflavones with a 4'-methoxy group. Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. Group: Enzymes. Synonyms: isoflavone 3'-monooxygenase. Enzyme Commission Number: EC 1.14.13.52. CAS No. 110183-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0859; isoflavone 3'-hydroxylase; EC 1.14.13.52; 110183-50-1; isoflavone 3'-monooxygenase. Cat No: EXWM-0859. | |
| vestitone reductase | This plant enzyme catalyses the penultimate step in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. This activity was previously classified as part of EC 1.1.1.246, pterocarpin synthase, which is now known to be catalysed by two enzymes, vestitone reductase and EC 4.2.1.139, medicarpin synthase. Group: Enzymes. Synonyms: pterocarpin synthase (incorrect); pterocarpan synthase (incorrect). Enzyme Commission Number: EC 1.1.1.348. CAS No. 118477-70-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0263; vestitone reductase; EC 1.1.1.348; 118477-70-6; pterocarpin synthase (incorrect); pterocarpan synthase (incorrect). Cat No: EXWM-0263. | |
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