Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Melphalan Hydrochloride | Melphalan is a phenylalanine derivative of nitrogen mustard and is a bifunctional alkylating agent which is useful against selected human neoplastic diseases. Synonyms: Melphalan HCl; Alkeran hydrochloride; CB 3025 hydrochloride; L-Sarcolysine hydrochloride; 4-Bis(2-chlorethyl)-amino-L-phenylalanine hydrochloride; (S)-2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoic acid hydrochloride. Grades: Assay: 98% - 102%. CAS No. 3223-7-2. Molecular formula: C13H19Cl3N2O2. Mole weight: 341.66. |  |
| DL-Melphalan hydrochloride | DL-Melphalan hydrochloride is an isomer of Melphalan hydrochloride. Melphalan is a chemotherapy drug that alters through alkylation of the DNA nucleotide guanine and causes the inhibition of DNA synthesis and RNA synthesis. Synonyms: Sarkoklorin; Sarkolizin; Sarcolysin hydrochloride; DL-Sarcolysine hydrochloride; 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid;hydrochloride. CAS No. 1465-26-5. Molecular formula: C13H19Cl3N2O2. Mole weight: 341.657. | |
| Melphalan Dimer Hydrochloride | Melphalan Dimer is an impurity from the synthesis of Melphanan, an antineoplastic. Synonyms: 4-[[2-[[4-[Bis(2-chloroethyl)amino]-L-phenylalanyl]oxy]ethyl](2-chloroethyl)amino]-L-phenylalanine Hydrochloride. Grades: > 95%. Molecular formula: C26H35Cl3N4O4·(HCl)x. Mole weight: 573.94. | |
| Melphalan Methyl Ester Hydrochloride | Melphalan Methyl Ester Hydrochloride is the methyl ester derivative of Melphalan, an antineoplastic. Synonyms: 4-[Bis(2-chloroethyl)amino]-L-phenylalanine Methyl Ester Hydrochloride; 4-[Bis(2-chloroethyl)amino]-L-phenylalanine Methyl Ester Monohydrochloride; NSC 133726. Grades: > 95%. CAS No. 62978-52-3. Molecular formula: C14H21Cl3N2O2. Mole weight: 355.69. | |
| Monohydroxy melphalan hydrochloride | Monohydroxy melphalan is a degradation product of melphalan via hydrolysis in cell culture and human plasma. It also acts as a DNA alkylating agent. Synonyms: Hydroxymelphalan hydrochloride. Grades: ≥95%. Molecular formula: C13H19ClN2O3·2HCl. Mole weight: 359.68. | |
| 3-Amino-6-[N,N-bis(3-chloropropyl)amino]-1,2,3,4-tetrahydro-2-oxo-quinoline Hydrochloride | 3-Amino-6-[N,N-bis(3-chloropropyl)amino]-1,2,3,4-tetrahydro-2-oxo-quinoline Hydrochloride is an impurity/intermediate of Melphalan (M216900), which is antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H22Cl3N3O, Molecular Weight: 366.71. US Biological Life Sciences. |  Worldwide |
| 4-Amino-D-phenylalanine hydrochloride | 4-Amino-D-phenylalanine Hydrochloride is used as a reagent in the synthesis of D-Melphalan, an isomer of Melphalan which is an antineoplastic. Synonyms: D-Phe(4-NH2)-OH HCl; p-Amino-D-Phe-OH HCl; (R)-2-amino-3-(4-aminophenyl)propionic acid hydrochloride; p-Amino-D-phenylalanine hydrochloride; P-Amino-d-phenylalanine HCl; H-P-Amino-D-Phe-OH HCl; H-Phe(4-NH2)-OH HCl; 4-Amino-D-phenylalanine hydrochloride; D-Phenylalanine,4-amino-, hydrochloride (9CI). Grades: ≥ 95%. CAS No. 126257-07-6. Molecular formula: C9H12N2O2·HCl. Mole weight: 216.66. | |
| Melflufen hydrochloride | Melflufen (Melphalan flufenamide) hydrochloride, a dipeptide proagent of Melphalan, is an alkylating agent. Melflufen hydrochloride shows antitumor activity against multiple myeloma (MM) cells and inhibits angiogenesis. Melflufen hydrochloride induces irreversible DNA damage and cytotoxicity in MM cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Melphalan flufenamide hydrochloride. CAS No. 380449-54-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105019A. |  |
| PX-478 dihydrochloride | PX-478 is an HIF-1alpha inhibitor and an orally active small molecule with potential antineoplastic activity. Although its mechanism of action has yet to be fully elucidated, HIF1-alpha inhibitor PX-478 appears to inhibit hypoxia-inducible factor 1-alpha (HIF1A) expression, which may result in decreased expression of HIF1A downstream target genes important to tumor growth and survival, a reduction in tumor cell proliferation, and the induction of tumor cell apoptosis. The inhibitory effect of this agent is independent of the tumor suppressor genes VHL and p53 and may be related to derangements in glucose uptake and metabolism due to inhibition of glucose transporter-1 (Glut-1). PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity. It is rapidly absorbed following oral and i.p. administration and gives excellent Cmax and AUC via these routes. Synonyms: PX-478 2HCl; PX-478 hydrochloride; Melphalan N-Oxide Impurity HCl; Melphalan N-Oxide Impurity hydrochloride; L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoamino]-, dihydrochloride; L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoamino]-, hydrochloride (1:2). Grades: > 98%. CAS No. 685898-44-6. Molecular formula: C13H18Cl2N2O3.2HCl. Mole weight: 394.1. | |
Our database is helping our users find suppliers everyday.
