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Menaquinone 4. Group: Biochemicals. Alternative Names: (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone; Glakay. Grades: Highly Purified. CAS No. 863-61-6. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C31H40O2. US Biological Life Sciences.
Worldwide
Menaquinone 4
Menaquinone 4 is a homolog of vitamin K2 with four isoprene residue in its side chain. Menaquinone 4 is the most common type of vitamin K2 and can be used for the pain of osteoporosis. Uses: Hemostatics. Synonyms: 1,4-Naphthalenedione, 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-; 1,4-Naphthalenedione, 2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-, (E,E,E)-; 1,4-Naphthalenedione, 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl]-; 2-Methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-1,4-naphthalenedione; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone; Glakay; K-viton; Kaytwo; Menaquinone K4; Menatetrenone; MK-4; Vitamin K2; Vitamin K2(20); Vitamin K2-4; Vitamin MK 4. Grades: ≥95%. CAS No. 863-61-6. Molecular formula: C31H40O2. Mole weight: 444.65.
Menaquinone-4
Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis. Uses: Scientific research. Group: Natural products. Alternative Names: Vitamin K2(MK-4); Menaquinone K4. CAS No. 863-61-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-B2156.
Menaquinone 4 2,3-epoxide
Menaquinone 4 2,3-epoxide. Group: Biochemicals. Alternative Names: 1a,7a-Dihydro-1a-methyl-7a-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-naphth[2,3-b]oxirene-2,7-dione; (E, E, E) -1a, 7a-Dihydro-1a-methyl-7a- (3, 7, 11, 15-tetramethyl-2, 6, 10, 14-hexadecatetraenyl) naphth[2, 3-b]oxirene-2, 7-dione; Menaquinone 4 epoxide. Grades: Highly Purified. CAS No. 72908-86-2. Pack Sizes: 10mg. Molecular Formula: C31H40O3. US Biological Life Sciences.
Worldwide
Menaquinone 4-d7 (Mixture of cis-trans isomers)
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 4-d7 is the labeled analogue of Menaquinone 4. Menaquinone-4 is the most common type of vitamin K2 and is known as a hemostatic agent and is used as adjunctive therapy for the pain of osteoporosis. Group: Biochemicals. Alternative Names: (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione-d7; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone-d7; Glakay-d7; Kaytwo-d7; MK4-d7; Menaquinone K4-d7; Menatetrenone-d7; Vitamin K2(20)-d7; Vitamin MK 4-d7. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Menaquinone 4 (Mixture of cis-trans isomers)
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 4 has four isoprene residue in its side chain and is also commonly refered to as menatetrenone. Menaquinone-4 is the most common type of vitamin K2 and is known as a hemostatic agent and is used as adjunctive therapy for the pain of osteoporosis. Group: Biochemicals. Alternative Names: (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione; 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone; Glakay; Kaytwo; MK4; Menaquinone K4; Menatetrenone; Vitamin K2(20); Vitamin MK 4. Grades: Highly Purified. CAS No. 863-61-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Menaquinone-4 (Standard)
Menaquinone-4 (Standard) is the analytical standard of Menaquinone-4. This product is intended for research and analytical applications. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis. Uses: Scientific research. Group: Natural products. CAS No. 863-61-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2156R.
Menaquinone 4 (Vitamin K2 (20), MK 4)
Menaquinone 4 (MK-4) is the predominant homolog of vitamin K2 and is composed of a naphthoquinone base with four isoprenoid units in the side chain.1 It is formed primarily via conversion of vitamin K1 (Item No. 21051) in vivo and accumulates in various tissues, including the brain.2,3 MK-4 halts the cell cycle at the G phase in HepG2, Hep3B, and Huh7 hepatocellular carcinoma cells in a concentration-dependent manner.4 It also inhibits I?B kinase (IKK) activity, I?Ba phosphorylation, and the transcriptional activity of NF-?B. Vitamin K2 may have a role in bone metabolism.1. Group: Biochemicals. Alternative Names: (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione; Menatetrenone; Vitamin K2(20); Kaytwo; MK 4. Grades: Purified. CAS No. 863-61-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C31H40O2. US Biological Life Sciences.
Worldwide
Menaquinone 5
Menaquinone 5. Group: Biochemicals. Alternative Names: 2-Methyl-3-[(2E,6E,10E,14E)-3,7,11,15,19-pentamethyl-2,6,10,14,18-eicosapentaen-1-yl]-1,4-naphthalenedione; 2-Methyl-3-farnesylgeranyl-1,4-naphthoquinone; Vitamin MK 5. Grades: Highly Purified. CAS No. 1182-68-9. Pack Sizes: 5mg. Molecular Formula: C36H48O2. US Biological Life Sciences.
Menaquinone 6. Group: Biochemicals. Alternative Names: (all-E)-2-(3,7,11,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaenyl)-3-methyl-1,4-naphthalenedione; Farnoquinone; MK6. Grades: Highly Purified. CAS No. 84-81-1. Pack Sizes: 5mg. Molecular Formula: C41H56O2. US Biological Life Sciences.
Worldwide
Menaquinone 6
Menaquinone 6 is a active product found in Wolinella succinogenes. Menaquinone 6 is a form of vitamin K2 (HY-109569) that has antimicrobial activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 84-81-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138137.
Menaquinone 6
Menaquinone 6 is a vitamin K2 homolog. Synonyms: Farnoquinone; Menaquinone-6; Vitamin MK6; Vitamin K2(30); 2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaenyl]-3-methylnaphthalene-1,4-dione. CAS No. 84-81-1. Molecular formula: C41H56O2. Mole weight: 580.897.
Menaquinone 7
Menaquinone 7 belongs to a class of K2-vitamin homologs originally discovered as the anti-hemorrhagic factors. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins, such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health. Applications: A bioactive cofactor for the carboxylation reaction of gla-proteins. Group: Coenzymes. Synonyms: (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione; Vitamin K2(35); Menaquinone K7. CAS No. 2124-57-4. Purity: ≥90%. Mole weight: 649. Form: Solid. (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione; Vitamin K2(35); Menaquinone K7; Menaquinone 7; 2124-57-4. Cat No: COEC-093.
Menaquinone 7
Menaquinone 7. CAS No: 2124-57-4
Sarchem Laboratories New Jersey NJ
Menaquinone-7
Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Vitamin K2-7; Vitamin K2(35); Vitamin MK-7. CAS No. 2124-57-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112499.
Menaquinone 7 (Vitamin K2 MK 7)
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 7 belongs to the class of K2-Vitamins homologs. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health. Group: Biochemicals. Alternative Names: (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione; Vitamin K2(35); Menaquinone K7; Vitamin MK 7. Grades: Highly Purified. CAS No. 2124-57-4,27670-94-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C46H64O2. US Biological Life Sciences.
Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 523-39-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-131501.
Menaquinone 9
Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 9 is a form of vitamin K2 which acts as a prothrombogenic agent and is also a functional electron transfer component in nitrate reductase. Group: Biochemicals. Alternative Names: 2-Methyl-3-[(2E, 6E, 10E, 14E, 18E, 22E, 26E, 30E)-3, 7, 11, 15, 19, 23, 27, 31, 35-nonamethyl-2, 6, 10, 14, 18, 22, 26, 30, 34-hexatriacontanonaen-1-yl]-. Grades: Highly Purified. CAS No. 523-39-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
demethylmenaquinone methyltransferase
The enzyme catalyses the last step in menaquinone biosynthesis. It is able to accept substrates with varying polyprenyl side chain length (the chain length is determined by polyprenyl diphosphate synthase). The enzyme from Escherichia coli also catalyses the conversion of 2-methoxy-6-octaprenyl-1,4-benzoquinone to 5-methoxy-2-methyl-3-octaprenyl-1,4-benzoquinone during the biosynthesis of ubiquinone. The enzyme probably acts on menaquinol rather than menaquinone. Group: Enzymes. Synonyms: S-adenosyl-L-methione-DMK methyltransferase; demethylmenaquinone C-methylase; 2-heptaprenyl-1,4-naphthoquinone methyltransferase; 2-demethylmenaquinone methyltransferase; S-adenosyl-L-methione:2-demethylmenaquinone methyltransferase. Enzyme Commission Number: EC 2.1.1.163. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1760; demethylmenaquinone methyltransferase; EC 2.1.1.163; S-adenosyl-L-methione-DMK methyltransferase; demethylmenaquinone C-methylase; 2-heptaprenyl-1,4-naphthoquinone methyltransferase; 2-demethylmenaquinone methyltransferase; S-adenosyl-L-methione:2-demethylmenaquinone methyltransferase. Cat No: EXWM-1760.
protoporphyrinogen IX dehydrogenase (menaquinone)
This enzyme enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments. Group: Enzymes. Synonyms: HemG. Enzyme Commission Number: EC 1.3.5.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1387; protoporphyrinogen IX dehydrogenase (menaquinone); EC 1.3.5.3; HemG. Cat No: EXWM-1387.
1,4-dihydroxy-2-naphthoate polyprenyltransferase
This enzyme catalyses a step in the synthesis of menaquinone, in which the prenyl chain synthesized by polyprenyl diphosphate synthase is transferred to 1,4-dihydroxy-2-naphthoate (DHNA). The bacterial enzyme is an inner membrane protein, with the C-terminus located in the periplasm. It is highly specific for DHNA but not for a specific length of the prenyl chain. Group: Enzymes. Enzyme Commission Number: EC 2.5.1.74. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2812; 1,4-dihydroxy-2-naphthoate polyprenyltransferase; EC 2.5.1.74. Cat No: EXWM-2812.
1,4-dihydroxy-2-naphthoyl-CoA hydrolase
This enzyme participates in the synthesis of menaquinones, phylloquinone, as well as several plant pigments. The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 does not accept benzoyl-CoA or phenylacetyl-CoA as substrates. Group: Enzymes. Synonyms: menI (gene name); ydiL (gene name). Enzyme Commission Number: EC 3.1.2.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3561; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase; EC 3.1.2.28; menI (gene name); ydiL (gene name). Cat No: EXWM-3561.
1,4-dihydroxy-2-naphthoyl-CoA synthase
This enzyme is involved in the synthesis of 1,4-dihydroxy-2-naphthoate, a branch point metabolite leading to the biosynthesis of menaquinone (vitamin K2, in bacteria), phylloquinone (vitamin K1 in plants), and many plant pigments.The coenzyme A group is subsequently removed from the product by EC 3.1.2.28, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase. Group: Enzymes. Synonyms: naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Enzyme Commission Number: EC 4.1.3.36. CAS No. 61328-42-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4913; 1,4-dihydroxy-2-naphthoyl-CoA synthase; EC 4.1.3.36; 61328-42-5; naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Cat No: EXWM-4913.
2,6-Dimethyl-8-(phenylmethoxy)-2,6-octadien-1-ol
2,6-Dimethyl-8-(phenylmethoxy)-2,6-octadien-1-ol is an intermediate in the synthesis of Menaquinone 6 (M218590). Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone-6 were the major isoprenoid quinones found in membrane preparations of Campylobacter jejuni and Campylobacter fetus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5g, 10g. Molecular Formula: C17H24O2. US Biological Life Sciences.
Worldwide
2,6-Dimethyl-8-(phenylmethoxy)-2,6-octadienal
2,6-Dimethyl-8-(phenylmethoxy)-2,6-octadienal is an intermediate in the synthesis of Menaquinone 6 (M218590). Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone-6 were the major isoprenoid quinones found in membrane preparations of Campylobacter jejuni and Campylobacter fetus. Group: Biochemicals. Grades: Highly Purified. CAS No. 117010-63-6. Pack Sizes: 5g, 10g. Molecular Formula: C17H22O2, Molecular Weight: 258.36. US Biological Life Sciences.
Requires Mg2+ for maximal activity. This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the products of the reaction were (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate (SHCHC), pyruvate and CO2 but it is now known that two separate enzymes are involved: this enzyme and EC 4.2.99.20, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. Under basic conditions, the product can spontaneously lose pyruvate to form SHCHC. Group: Enzymes. Synonyms: SEPHCHC synthase; MenD. Enzyme Commission Number: EC 2.2.1.9. CAS No. 1112282-73-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2036; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase; EC 2.2.1.9; 1112282-73-1; SEPHCHC synthase; MenD. Cat No: EXWM-2036.
This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the reactions carried out by this enzyme and EC 2.2.1.9, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase, were carried out by a single enzyme but this has since been disproved. Group: Enzymes. Synonyms: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase; 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase; SHCHC synthase; MenH; YfbB. Enzyme Commission Number: EC 4.2.99.20. CAS No. 122007-88-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5266; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; EC 4.2.99.20; 122007-88-9; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase; 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase; SHCHC synthase; MenH; YfbB. Cat No: EXWM-5266.
all-trans-decaprenyl-diphosphate synthase
This enzyme catalyses the condensation reactions resulting in the formation of all-trans-decaprenyl diphosphate, the isoprenoid side chain of ubiquinone-10 and menaquinone-10. The enzyme adds seven isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. Group: Enzymes. Synonyms: decaprenyl-diphosphate synthase; decaprenyl pyrophosphate synthetase; polyprenylpyrophosphate synthetase; terpenoidallyltransferase; terpenyl pyrophosphate synthetase; trans-prenyltransferase. Enzyme Commission Number: EC 2.5.1.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2830; all-trans-decaprenyl-diphosphate synthase; EC 2.5.1.91; decaprenyl-diphosphate synthase; decaprenyl pyrophosphate synthetase; polyprenylpyrophosphate synthetase; terpenoidallyltransferase; terpenyl pyrophosphate synthetase; trans-prenyltransferase. Cat No: EXWM-2830.
(2E,6E)-Farnesyl diphosphate and geranylgeranyl diphosphate are less effective as substrates than geranyl diphosphate. The enzyme is involved in the synthesis of the side chain of menaquinone-9. In Oryza sativa the enzyme SPS2 is involved in providing solanesyl diphosphate for plastoquinone-9 formation. Group: Enzymes. Synonyms: nonaprenyl diphosphate synthase (ambiguous); solanesyl diphosphate synthase (ambiguous); SolPP synthase (ambiguous); SPP-synthase (ambiguous); SPP synthase (ambiguous); solanesyl-diphosphate synthase (ambiguous); OsSPS2. Enzyme Commission Number: EC 2.5.1.84. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2822; all-trans-nonaprenyl-diphosphate synthase [geranyl-diphosphate specific]; EC 2.5.1.84; nonaprenyl diphosphate synthase (ambiguous); solanesyl diphosphate synthase (ambiguous); SolPP synthase (ambiguous); SPP-synthase (ambiguous); SPP synthase (ambiguous); solanesyl-diphosphate synthase (ambiguous); OsSPS2. Cat No: EXWM-2822.
all-trans-octaprenyl-diphosphate synthase
This enzyme catalyses the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate, the isoprenoid side chain of ubiquinone-8 and menaquinone-8. The enzyme adds five isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. Group: Enzymes. Synonyms: octaprenyl-diphosphate synthase; octaprenyl pyrophosphate synthetase; polyprenylpyrophosphate synthetase; terpenoidallyltransferase; terpenyl pyrophosphate synthetase; trans-heptaprenyltranstransferase; trans-prenyltransferase. Enzyme Commission Number: EC 2.5.1.90. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2829; all-trans-octaprenyl-diphosphate synthase; EC 2.5.1.90; octaprenyl-diphosphate synthase; octaprenyl pyrophosphate synthetase; polyprenylpyrophosphate synthetase; terpenoidallyltransferase; terpenyl pyrophosphate synthetase; trans-heptaprenyltranstransferase; trans-prenyltransferase. Cat No: EXWM-2829.
aminodeoxyfutalosine deaminase
The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis. Group: Enzymes. Synonyms: AFL deaminase; aminofutalosine deaminase; mqnX (gene name). Enzyme Commission Number: EC 3.5.4.40. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4569; aminodeoxyfutalosine deaminase; EC 3.5.4.40; AFL deaminase; aminofutalosine deaminase; mqnX (gene name). Cat No: EXWM-4569.
aminodeoxyfutalosine nucleosidase
The enzyme, found in several bacterial species, catalyses a step in a modified futalosine pathway for menaquinone biosynthesis. While the enzyme from some organisms also has the activity of EC 3.2.2.9, adenosylhomocysteine nucleosidase, the enzyme from Chlamydia trachomatis is specific for 6-amino-6-deoxyfutalosine. Group: Enzymes. Synonyms: AFL nucleosidase; aminofutalosine nucleosidase; methylthioadenosine nucleosidase; MqnB. Enzyme Commission Number: EC 3.2.2.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3985; aminodeoxyfutalosine nucleosidase; EC 3.2.2.30; AFL nucleosidase; aminofutalosine nucleosidase; methylthioadenosine nucleosidase; MqnB. Cat No: EXWM-3985.
aminodeoxyfutalosine synthase
This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the transferred adenosyl group. The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis. Group: Enzymes. Synonyms: MqnE; AFL synthase; aminofutalosine synthase; S-adenosyl-L-methionine:3-[(1-carboxyvinyl)-oxy]benzoate adenosyltransferase (bicarbonate-hydrolysing, 6-amino-6-deoxyfutalosine-forming). Enzyme Commission Number: EC 2.5.1.120. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2736; aminodeoxyfutalosine synthase; EC 2.5.1.120; MqnE; AFL synthase; aminofutalosine synthase; S-adenosyl-L-methionine:3-[(1-carboxyvinyl)-oxy]benzoate adenosyltransferase (bicarbonate-hydrolysing, 6-amino-6-deoxyfutalosine-forming). Cat No: EXWM-2736.
chorismate dehydratase
The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis. Group: Enzymes. Synonyms: MqnA. Enzyme Commission Number: EC 4.2.1.151. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4992; chorismate dehydratase; EC 4.2.1.151; MqnA. Cat No: EXWM-4992.
cyclic dehypoxanthinyl futalosine synthase
This enzyme is a member of the 'AdoMet radical' (radical SAM) family. The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis. Group: Enzymes. Synonyms: MqnC; dehypoxanthinyl futalosine cyclase. Enzyme Commission Number: EC 1.21.98.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1260; cyclic dehypoxanthinyl futalosine synthase; EC 1.21.98.1; MqnC; dehypoxanthinyl futalosine cyclase. Cat No: EXWM-1260.
formate dehydrogenase-N
The enzyme contains molybdopterin-guanine dinucleotides, five [4Fe-4S] clusters and two heme b groups. Formate dehydrogenase-N oxidizes formate in the periplasm, transferring electrons via the menaquinone pool in the cytoplasmic membrane to a dissimilatory nitrate reductase (EC 1.7.5.1), which transfers electrons to nitrate in the cytoplasm. The system generates proton motive force under anaerobic conditions. Group: Enzymes. Synonyms: Fdh-N; FdnGHI; nitrate-inducible formate dehydrogenase; formate dehydrogenase N; FDH-N; nitrate inducible Fdn; nitrate inducible formate dehydrogenase. Enzyme Commission Number: EC 1.1.5.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0434; formate dehydrogenase-N; EC 1.1.5.6; Fdh-N; FdnGHI; nitrate-inducible formate dehydrogenase; formate dehydrogenase N; FDH-N; nitrate inducible Fdn; nitrate inducible formate dehydrogenase. Cat No: EXWM-0434.
fumarate reductase (quinol)
The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain. The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, succinate dehydrogenase (quinone), to which it is closely related. Group: Enzymes. Synonyms: FRD; menaquinol-fumarate oxidoreductase; succinate dehydrogenase (menaquinone); succinate:menaquinone oxidoreductase; fumarate reductase (menaquinone); complex II (ambiguous). Enzyme Commission Number: EC 1.3.5.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1388; fumarate reductase (quinol); EC 1.3.5.4; FRD; menaquinol-fumarate oxidoreductase; succinate dehydrogenase (menaquinone); succinate:menaquinone oxidoreductase; fumarate reductase (menaquinone); complex II (ambiguous). Cat No: EXWM-1388.
futalosine hydrolase
This enzyme, which is specific for futalosine, catalyses the second step of a novel menaquinone biosynthetic pathway that is found in some prokaryotes. Group: Enzymes. Synonyms: futalosine nucleosidase; MqnB. Enzyme Commission Number: EC 3.2.2.26. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3980; futalosine hydrolase; EC 3.2.2.26; futalosine nucleosidase; MqnB. Cat No: EXWM-3980.
heptaprenyl diphosphate synthase
This enzyme catalyses the condensation reactions resulting in the formation of all-trans-heptaprenyl diphosphate, the isoprenoid side chain of ubiquinone-7 and menaquinone-7. The enzyme adds four isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. Group: Enzymes. Synonyms: all-trans-heptaprenyl-diphosphate synthase; heptaprenyl pyrophosphate synthase; heptaprenyl pyrophosphate synthetase; HepPP synthase; HepPS; heptaprenylpyrophosphate synthetase. Enzyme Commission Number: EC 2.5.1.30. CAS No. 74506-59-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2768; heptaprenyl diphosphate synthase; EC 2.5.1.30; 74506-59-5; all-trans-heptaprenyl-diphosphate synthase; heptaprenyl pyrophosphate synthase; heptaprenyl pyrophosphate synthetase; HepPP synthase; HepPS; heptaprenylpyrophosphate synthetase. Cat No: EXWM-2768.
hydrogen:quinone oxidoreductase
Contains nickel, iron-sulfur clusters and cytochrome b. Also catalyses the reduction of water-soluble quinones (e.g. 2,3-dimethylnaphthoquinone) or viologen dyes (benzyl viologen or methyl viologen). Group: Enzymes. Synonyms: hydrogen-ubiquinone oxidoreductase; hydrogen:menaquinone oxidoreductase; membrane-bound hydrogenase; quinone-reactive Ni/Fe-hydrogenase. Enzyme Commission Number: EC 1.12.5.1. CAS No. 151616-65-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0522; hydrogen:quinone oxidoreductase; EC 1.12.5.1; 151616-65-8; hydrogen-ubiquinone oxidoreductase; hydrogen:menaquinone oxidoreductase; membrane-bound hydrogenase; quinone-reactive Ni/Fe-hydrogenase. Cat No: EXWM-0522.
Menadione
Precursor to verious types of Vitamin K. Used as a micronutrient for livestock and pet foods. Group: Biochemicals. Alternative Names: 2-Methyl-1,4-naphthoquinone; 1,4-Dihydro-1,4-dioxo-2-methylnaphthalene; 2-Methyl-1,4-naphthalenedione; Aquakay; Aquinone; Hemodal; K-Thrombyl; K-Vitan; Kaergona; Kanone; Kappaxan; Kappaxin; Karcon; Kareon; Kativ-G; Kayklot; Kaykot; Kaynone; Kayquinone; Kipca; Kipca-Oil Soluble; Klottone; Koaxin; Kolklot; MNQ; Menadion; Menadione; Menaphthon; Menaphthone; Menaquinone 0; Mitenon; Mitenone; NSC 4170; Panosine; Prokayvit; Synkay; Thyloquinone. Grades: Highly Purified. CAS No. 58-27-5. Pack Sizes: 100g, 250g, 500g. Molecular Formula: C??H?O?, Molecular Weight: 172.18. US Biological Life Sciences.
Worldwide
Menaquinon-9
Menaquinon-9. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Phylloquinone,(Z); Phytonadione,(Z); [R-[R*,R*-(Z)]]-2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione; 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl]naphthoquinone; 2-methyl-3-((E)-3,7,11,15-tetramethyl-hex. Product Category: Heterocyclic Organic Compound. Appearance: yellow crystals. CAS No. 863-61-3. Molecular formula: C56H80O2. Mole weight: 883.748068;g/mol. Purity: 0.96. IUPACName: trisodium;(3E)-3-[[4-[4-[[4-[(2Z)-2-(7-amino-1-oxo-3-sulfonatonaphthalen-2-ylidene)hydrazinyl]-7-sulfonatonaphthalen-1-yl]diazenyl]phenyl]phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylate. Canonical SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)N=NC3=C4C=C(C=CC4=C(C=C3)NN=C5C(=CC6=C(C5=O)C=C(C=C6)N)S(=O)(=O)[O-])S(=O)(=O)[O-])NN=C7C=CC(=O)C(=C7)C(=O)[O-].[Na+].[Na+].[Na+]. Density: 0.994 g/cm³. Product ID: ACM863613. Alfa Chemistry ISO 9001:2015 Certified. Categories: Menaquinone.
NADH dehydrogenase (quinone)
Menaquinone can act as acceptor. Inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. Group: Enzymes. Synonyms: reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase; NADH-quinone oxidoreductase; DPNH-menadione reductase; D-diaphorase; NADH2 dehydrogenase (quinone). Enzyme Commission Number: EC 1.6.5.11. CAS No. 37256-36-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1589; NADH dehydrogenase (quinone); EC 1.6.5.11; 37256-36-3; reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase; NADH-quinone oxidoreductase; DPNH-menadione reductase; D-diaphorase; NADH2 dehydrogenase (quinone). Cat No: EXWM-1589.
o-succinylbenzoate-CoA ligase
O-succinylbenzoate CoA ligase (EC 6.2.1.26), encoded from the menE gene in Escherichia coli, catalyzes the fifth reaction in the synthesis of menaquinone (vitamin K2). This pathway is called 1, 4-dihydroxy-2-naphthoate biosynthesis I. Vitamin K is a quinone that serves as an electron transporter during anaerobic respiration. This process of anaerobic respiration allows the bacteria to generate the energy required to survive. Group: Enzymes. Synonyms: o-succinylbenzoyl-coenzyme A synthetase; o-succinylbenzoate:CoA ligase (AMP-forming). Enzyme Commission Number: EC 6.2.1.26. CAS No. 72506-70-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5684; o-succinylbenzoate-CoA ligase; EC 6.2.1.26; 72506-70-8; o-succinylbenzoyl-coenzyme A synthetase; o-succinylbenzoate:CoA ligase (AMP-forming). Cat No: EXWM-5684.
phenylacetyl-CoA dehydrogenase
The enzyme from Thauera aromatica is a membrane-bound molybdenum-iron-sulfur protein. The enzyme is specific for phenylacetyl-CoA as substrate. Phenylacetate, acetyl-CoA, benzoyl-CoA, propanoyl-CoA, crotonyl-CoA, succinyl-CoA and 3-hydroxybenzoyl-CoA cannot act as substrates. The oxygen atom introduced into the product, phenylglyoxylyl-CoA, is derived from water and not molecular oxygen. Duroquinone, menaquinone and 2,6-dichlorophenolindophenol (DCPIP) can act as acceptor, but the likely physiological acceptor is ubiquinone. A second enzyme, EC 3.1.2.25, phenylacetyl-CoA hydrolase, converts the phenylglyoxylyl-CoA formed into phenylglyoxylate. Group: Enzymes. Synonyms: phenylacetyl-CoA:acceptor oxidoreductase. Enzyme Commission Number: EC 1.17.5.1. CAS No. 210756-43-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1094; phenylacetyl-CoA dehydrogenase; EC 1.17.5.1; 210756-43-7; phenylacetyl-CoA:acceptor oxidoreductase. Cat No: EXWM-1094.
phylloquinone ω-hydroxylase
A heme-thiolate protein (cytochrome P-450). Isolated from human tissue. The enzyme will also act on menaquinone-4. Prolonged action of CYP4F2, but not CYP4F11, on the ω hydroxyl group oxidizes it to the corresponding carboxylic acid. CYP4F2 also oxidizes leukotriene B4; see EC 1.14.13.30, leukotriene-B4 20-monooxygenase. Group: Enzymes. Synonyms: vitamin K1 ω-hydroxylase; CYP4F2; CYP4F11. Enzyme Commission Number: EC 1.14.13.194. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0794; phylloquinone ω-hydroxylase; EC 1.14.13.194; vitamin K1 ω-hydroxylase; CYP4F2; CYP4F11. Cat No: EXWM-0794.
pyruvate dehydrogenase (quinone)
Flavoprotein (FAD). This bacterial enzyme is located on the inner surface of the cytoplasmic membrane and coupled to the respiratory chain via ubiquinone. Does not accept menaquinone. Activity is greatly enhanced by lipids. Requires thiamine diphosphate. The enzyme can also form acetoin. Group: Enzymes. Synonyms: pyruvate dehydrogenase; pyruvic dehydrogenase; pyruvic (cytochrome b1) dehydrogenase; pyruvate:ubiquinone-8-oxidoreductase; pyruvate oxidase (ambiguous); pyruvate dehydrogenase (cytochrome) (incorrect). Enzyme Commission Number: EC 1.2.5.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1220; pyruvate dehydrogenase (quinone); EC 1.2.5.1; pyruvate dehydrogenase; pyruvic dehydrogenase; pyruvic (cytochrome b1) dehydrogenase; pyruvate:ubiquinone-8-oxidoreductase; pyruvate oxidase (ambiguous); pyruvate dehydrogenase (cytochrome) (incorrect). Cat No: EXWM-1220.
succinate dehydrogenase
A flavoprotein (FAD) complex containing iron-sulfur centres. The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of many aerobic or facultative bacteria and archaea. It catalyses succinate oxidation in the citric acid cycle and transfers the electrons to quinones in the membrane, thus constituting a part of the aerobic respiratory chain (known as complex II). In vivo the enzyme uses the quinone found in the organism - eukaryotic enzymes utilize ubiquinone, bacterial enzymes utilize ubiquinone or menaquinone, and archaebacterial enzymes from the Sulfolobus genus use caldariellaquinone. cf. EC 1.3.5.4, fumarate reductase (quinone). Group: Enzymes. Synonyms: succinate dehydrogenase (quinone); succinate dehydrogenase (ubiquinone); succinic dehydrogenase; complex II (ambiguous); succinate dehydrogenase complex; SDH; succinate:ubiquinone oxidoreductase. Enzyme Commission Number: EC 1.3.5.1. CAS No. 9028-11-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1385; succinate dehydrogenase; EC 1.3.5.1; 9028-11-9; succinate dehydrogenase (quinone); succinate dehydrogenase (ubiquinone); succinic dehydrogenase; complex II (ambiguous); succinate dehydrogenase complex; SDH; succinate:ubiquinone oxidoreductase. Cat No: EXWM-1385.
sulfide:quinone reductase
Contains FAD. Ubiquinone, plastoquinone or menaquinone can act as acceptor in different species. This enzyme catalyses the formation of sulfur globules. It is also an important step in anoxygenic bacterial photosynthesis. Group: Enzymes. Enzyme Commission Number: EC 1.8.5.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1679; sulfide:quinone reductase; EC 1.8.5.4. Cat No: EXWM-1679.
tetrachloroethene reductive dehalogenase
This enzyme allows the common pollutant tetrachloroethene to support bacterial growth and is responsible for disposal of a number of chlorinated hydrocarbons by this organism. The reaction occurs in the reverse direction. The enzyme also reduces trichloroethene to dichloroethene. Although the physiological reductant is unknown, the supply of reductant in some organisms is via reduced menaquinone, itself formed from molecular hydrogen, via EC 1.12.5.1 (hydrogen:quinone oxidoreductase). The enzyme contains a corrinoid and two iron-sulfur clusters. Methyl viologen can act as electron donor. Group: Enzymes. Synonyms: tetrachloroethene reductase. Enzyme Commission Number: EC 1.97.1.8. CAS No. 163913-51-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1694; tetrachloroethene reductive dehalogenase; EC 1.97.1.8; 163913-51-7; tetrachloroethene reductase. Cat No: EXWM-1694.