Messenger Ribo Suppliers USA
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Product | Description | |
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2',2''-Di-c-didGMP Quick inquiry Where to buy Suppliers range | 2',2''-Di-c-didGMP is an analogue of c-diGMP, the bacterial second messenger, which selectively binds the c-diGMP class II riboswitch. It can be used to discriminate between class I and class II of c-diGMP-binding RNAs and to study RNA-based c-diGMP signalling. Synonyms: 2'- , 2''- Dideoxy- cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 60307-63-3. Molecular formula: C20H24N10O12P2 (free acid). Mole weight: 658.4 (free acid). | |
2',2''-Di-O-Me-c-diGMP Quick inquiry Where to buy Suppliers range | 2',2''-Di-O-Me-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which selectively binds the c-diGMP class II riboswitch. It can be used to discriminate between class I and class II of c-diGMP-binding RNAs and to study RNA-based c-diGMP signalling. Synonyms: 2'- , 2''- O- (Di- methyl)- cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 849214-02-4. Molecular formula: C22H28N10O14P2 (free acid). Mole weight: 718.5 (free acid). | |
4-N-cBIMP Quick inquiry Where to buy Suppliers range | 4-N-cBIMP is an analogue of cAMP, the second messenger, which has a changed interaction potential at position 6. Synonyms: 4- Nitrobenzimidazole riboside- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 127634-21-3. Molecular formula: C12H11N3O8P ยท Na. Mole weight: 379.2. | |
8-AET-2'-O-Me-cAMP-Agarose Quick inquiry Where to buy Suppliers range | 8-AET-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxyl group immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cAMP-responsive proteins such as the exchange protein activated by cAMP (Epac) and certain phosphodiesterases. Synonyms: 8- (2- Aminoethylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, immobilized on agarose gel. | |
8-AHA-2'-O-Me-cAMP-Agarose Quick inquiry Where to buy Suppliers range | 8-AHA-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cAMP-responsive proteins such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Synonyms: 8- (6- Aminohexylamino)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel. | |
β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate Quick inquiry Where to buy Suppliers range | β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Synonyms: Adenosine 5'-(Trihydrogen Diphosphate), P'?5'-Ester with 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium Hydroxide Sodium Salt Hydrate; Adenine-nicotinamide Dinucleotide Sodium Salt Hydrate; CO-I Sodium Salt Hydrate; Codehydrase I Sodium Salt Hydrate; Codehydrogenase I Sodium Salt Hydrate; Coenzyme I Sodium Salt Hydrate; Cozymase I Sodium Salt Hydrate; DPN Sodium Salt Hydrate; Diphosphopyridine Nucleotide Sodium Salt Hydrate; Enzopride Sodium Salt Hydrate; NAD Sodium Salt Hydrate; NAD+ Sodium Salt Hydrate; NSC 20272 Sodium Salt Hydrate; Nadide Sodium Salt Hydrate; Nicotinamide-adenine Dinucleotide Sodium Salt Hydrate; Oxidized diphosphopyridine Nucleotide Sodium Salt Hydrate; β-Diphosphopyridine Nucleotide Sodium Salt Hydrate; β-NAD Sodium Salt Hydrate; β-NAD+ Sodium Salt Hydrate. Grades: 95%. Molecular formula: C21H26N7NaO14P2 X(H2O). Mole weight: 685.41. | |
cADP-Ribose (cADPR) Ammonium Salt Quick inquiry Where to buy Suppliers range | Cyclic ADP-ribose ammonium is a potent calcium-mobilized second messenger synthesized from NAD+ by ADP-ribosyl cyclase. It increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and extracellular influx through the opening of TRPM2 channels. Synonyms: cADP-Ribose Ammonium Salt; cADPR Ammonium Salt; cyclic ADP-ribose ammonium salt; Cyclic Adenosine Diphosphate Ribose ammonium salt; Cyclic adenosine 5'-diphosphate ribose ammonium salt. Grades: 90%. Molecular formula: C15H21N5O13P2.x(NH3). Mole weight: 541.30 (free base). | |
Guanosine 3',5'-cyclic monophosphate Quick inquiry Where to buy Suppliers range | Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Synonyms: D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate; 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-1H-purin-6-one. Grades: ≥ 95%. CAS No. 7665-99-8. Molecular formula: C10H12N5O7P. Mole weight: 345.21. | |
Guanosine 5'-Diphosphate Triammonium Salt Quick inquiry Where to buy Suppliers range | Guanosine 5'-Diphosphate Triammonium Salt is an intermediate in the eukaryotic messenger ribonucleic acid cap binding protein synthesis. Synonyms: Guanosine 5'-(Trihydrogen Diphosphate), Triammonium Salt; Triammonium Guanosine 5'-Diphosphate. CAS No. 79441-34-2. Molecular formula: C10H16N6O11P2. Mole weight: 458.22. | |
Guanylyl-(3',5')-adenosine Quick inquiry Where to buy Suppliers range | Guanylyl-(3',5')-adenosine, a cyclic nucleotide second messenger, intricately orchestrates various cellular signaling pathways, rendering it crucial in regulating a myriad of physiological functions, ranging from neurotransmitter release to smooth muscle contraction. A versatile molecule of interest, this compound boasts promising potential in the therapeutic arena, especially for treating cardiovascular diseases, such as hypertension and heart failure, thanks to its adeptness in modulating platelet activation and gene expression. Synonyms: Guanine ribonucleotidyl-(3'-5')-adenosine; Adenylyl-(5',3')-guanosine; GpA RNA Dinucleotide (5'-3'). Grades: ≥95% by AX-HPLC. CAS No. 6554-00-3. Molecular formula: C20H25N10O11P. Mole weight: 612.40. | |
N1-MethylpseudoUridine-5'-Triphosphate Quick inquiry Where to buy Suppliers range | N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stock. Synonyms: 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-; 1-Methylpseudo-UTP. Grades: ≥95%. CAS No. 1428903-59-6. Molecular formula: C10H17N2O15P3. Mole weight: 498.17. | |
N1-MethylpseudoUridine-5'-Triphosphate Lithium Quick inquiry Where to buy Suppliers range | N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stock. Synonyms: 1-Methylpseudouridine-5'-Triphosphate lithium salt; N1-Methylpseudo-UTP tetralithium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-, lithium salt; 1-Methylpseudo-UTP tetralithium salt. Grades: ≥90% by AX-HPLC. Molecular formula: C10H13Li4N2O15P3. Mole weight: 521.89. | |
N1-MethylpseudoUridine-5'-Triphosphate Sodium Quick inquiry Where to buy Suppliers range | It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The product has passed the functionality test in transcription reaction. The solution is free of DNase and RNase contamination. Synonyms: 1-Methylpseudouridine-5'-Triphosphate sodium salt; N1-Methylpseudo-UTP sodium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-, sodium salt; 1-Methylpseudo-UTP sodium salt; 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP. Grades: 99%, 100mM sodium salt solution. Molecular formula: C10H17N2O15P3.xNa. Mole weight: 498.17 (free acid). | |
Nicotinic Acid Adenine Dinucleotide Quick inquiry Where to buy Suppliers range | Nicotinic Acid Adenine Dinucleotide is an analog of β-Nicotinamide Adenine Dinucleotide; a coenzyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate groups. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Synonyms: Adenosine 5'-(trihydrogen diphosphate), P'?5'-ester with 3-carboxy-1-β-D-ribofuranosylpyridinium, inner salt; 3-Carboxy-1-β-D-ribofuranosylpyridinium hydroxide, 5'-ester with adenosine 5'-pyrophosphate, inner salt; Pyridinium, 3-carboxy-1-β-D-ribofuranosyl-, hydroxide, 5'?5'-ester with adenosine 5'-(trihydrogen pyrophosphate), inner salt; 1: PN: WO2006081329 PAGE: 47 claimed sequence; Adenine-nicotinic Acid Dinucleotide; Codehydrogenase I, carboxy deamido analog; Codehydrogenase I, nicotinic acid analog; Deamido-NAD; Deamidodiphosphopyridine Nucleotide; Desamido NAD; Nicotinate Adenine Dinucleotide; Nicotinic Acid-adenine Dinucleotide. CAS No. 6450-77-7. Molecular formula: C21H26N6O15P2. Mole weight: 664.41. | |
pApG Quick inquiry Where to buy Suppliers range | pApG is a metabolite of 3'3'-cGAMP, the bacterial second messenger, which is generated by specific PDEs in Vibrio cholerae. pApG does not bind to the c-diGMP-I riboswitch. Synonyms: 5'- Phosphoadenylyl- (3' -≥ 5')- guanosine, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 5064-50-6. Molecular formula: C20H26N10O14P2. Mole weight: 692.4. |