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A labeled metabolite of Mazindol. An imidazolinylphenyl ketone derivatives as antidepressants and diuretics. Group: Biochemicals. Alternative Names: 2-(2-Aminoethyl-d4)-3-(4-chlorophenyl)-2,3-dihydro-3-hydroxy-1H-isoindol-1-one Hydrochloride. Grades: Highly Purified. CAS No. 1276611-52-9. Pack Sizes: 2.5mg. US Biological Life Sciences.
A metabolite of Mazindol. An imidazolinylphenyl ketone derivatives as antidepressants and diuretics. Group: Biochemicals. Alternative Names: 2-(2-Aminoethyl)-3-(4-chlorophenyl)-2,3-dihydro-3-hydroxy-1H-isoindol-1-one Hydrochloride. Grades: Highly Purified. CAS No. 13473-53-5. Pack Sizes: 5mg. US Biological Life Sciences.
A metabolite of Repaglinide. Repaglinide is an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Synonyms: 4-[2-[[1-[2-[(4-Carboxybutyl)amino]phenyl]-3-methylbutyl]amino]-2-oxoethyl]-2-ethoxybenzoic Acid; Repaglinide M2 metabolite. Grades: > 95%. CAS No. 874908-12-0. Molecular formula: C27H36N2O6. Mole weight: 484.6.
3-Mesityl-2-oxo-1-oxaspiro[4.4]non-3-en-4-ol(Spiromesifen Metabolite M01). Group: Biochemicals. Alternative Names: 4-Hydroxy-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-2-one. Grades: Highly Purified. CAS No. 148476-30-6. Pack Sizes: 10mg. Molecular Formula: C17H20O3, Molecular Weight: 272.339999999999. US Biological Life Sciences.
Worldwide
3-Morpholine Metabolite
A metabolite of Esreboxetine. Esreboxetine is a selective norepinephrine reuptake inhibitor for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. Synonyms: 6-[(2-ethoxyphenoxy)?phenylmethyl]?- 3-Morpholinone. Grades: > 95%. CAS No. 93886-32-9. Molecular formula: C19H21NO4. Mole weight: 327.38.
A metabolite of Paroxetine. Group: Biochemicals. Alternative Names: 5-[[(3S,4R)-4-(4-Fluorophenyl)-3-piperidinyl]methoxy]-2-methoxy-phenol; BRL 36583A; (-)-trans 4-(4-Fluorophenyl)-3-(3-hydroxy-4-methoxyphenoxymethyl) piperidine. Grades: Highly Purified. CAS No. 112058-89-6. Pack Sizes: 1mg, 2mg. US Biological Life Sciences.
Worldwide
5-Hydroxy Deferasirox(Metabolite M1)
5-Hydroxy Deferasirox is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 4-[3-(2,5-Dihydroxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid. CAS No. 524746-12-1. Molecular formula: C21H15N3O5. Mole weight: 389.36.
5'-Hydroxy Deferasirox(Metabolite M4)
5'-Hydroxy Deferasirox is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: 4-[5-(2,5-Dihydroxyphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid. CAS No. 524746-13-2. Molecular formula: C21H15N3O5. Mole weight: 389.36.
AB-CHMINACA metabolite M4-d4
AB-CHMINACA metabolite M4-d4 is a deuterium labelled metabolite of AB-CHMINACA which is a synthetic cannabinoid, structurally related to AB-CHMINACA metabolite M5A (A106010). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C15H14D4N2O2, Molecular Weight: 262.339999999999. US Biological Life Sciences.
Worldwide
AB-CHMINACA metabolite M7
AB-CHMINACA metabolite M7 is an indazole-based synthetic cannabinoid (CB) that is structurally related to AB-FUBINACA, a high affinity ligand of the central CB1 receptor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500μg, 1mg. Molecular Formula: C20H25N3O5, Molecular Weight: 387.43. US Biological Life Sciences.
Worldwide
Abemaciclib metabolite M18 hydrochloride
Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LSN3106729 hydrochloride. CAS No. 2704316-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126534A.
Abiraterone Metabolite
Abiraterone Metabolite. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1940176-03-3. Molecular Formula: C24H33NO. Mole Weight: 351.53. Catalog: APB1940176033.
A metabolite of Alvimopan. Synonyms: ADL 08-0011. Grades: > 95%. CAS No. 156130-41-5. Molecular formula: C23H29NO3. Mole weight: 367.49.
Amlodipine Metabolite 4
Amlodipine Metabolite 4 is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: O-Des[2-aminoethyl]-O-carboxymethyl-dehydroamlodipine; 2-[(carboxymethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3-ethyl 5-methyl Ester 3,5-pyridinedicarboxylic Acid. Grades: >95%. CAS No. 113994-45-9. Molecular formula: C20H20ClNO7. Mole weight: 421.83.
Amlodipine Metabolite 4 Hydrochloride
Amlodipine Metabolite 4 Hydrochloride is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: 2-[(carboxymethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3-ethyl 5-methyl Ester 3,5-pyridinedicarboxylic Acid Hydrochloride; O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine Hydrochloride. Grades: >95%. Molecular formula: C20H20ClNO7.HCl. Mole weight: 458.29.
Amlodipine Metabolite 5
Amlodipine Metabolite 5 is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: 2-[(Carboxymethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-3,5-Pyridinedicarboxylic Acid 3-Ethyl Ester. CAS No. 114018-75-6. Molecular formula: C19H18ClNO7. Mole weight: 407.8.
Aprepitant-M3 Metabolite
Aprepitant-M3 Metabolite is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: An active metabolite of aprepitant. Synonyms: (5S,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone; Aprepitant-M3; 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5S,6R)-. Grades: ≥95%. CAS No. 419574-04-2. Molecular formula: C20H16F7NO3. Mole weight: 451.33.
Aripiprazole Metabolite
A metabolite of Aripiprazole. Synonyms: Aripiprazole Butanoic Acid Impurity. Grades: > 95%. CAS No. 58899-27-7. Molecular formula: C13H15NO4. Mole weight: 249.27.
Avanafil metabolite M4
Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil. Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanafil metabolite M4 and avanafil metabolite M16, as well as minor metabolites. Avanafil metabolite M4 inhibits PDE5 with 18% of the potency of avanafil. Grades: ≥98%. Molecular formula: C23H26ClN7O4. Mole weight: 499.95.
BB-22 3-Carboxyindole Metabolite
BB-22 3-Carboxyindole Metabolite is an intermediate of MDMB-CHMICA (M199520). MDMB-CHMICA is an analogue of N-[(1S)-1-(Aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide (A603135), an indazole derivative developed as a CB1 receptor modulator used in the treatment of CB1-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 858515-71-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H19NO2. US Biological Life Sciences.
Worldwide
Bictegravir Metabolite M15
Bictegravir Metabolite M15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3S,4S,5R)-6-(((2R)-5,7-dioxo-2-propyl-8-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazin-6-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. CAS No. 2365156-60-9. Molecular Formula: C27H26F3N3O11. Mole Weight: 625.5. Catalog: APB2365156609.
Cyclosporine metabolite M17 is a metabolite of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Synonyms: Cyclosporin AM 1; 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite M17; Cyclosporin metabolite AM1; OL-17; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 33-[(1R,2R,4E)-1,6-dihydroxy-2-methyl-4-hexen-1-yl]-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S, 6S, 9S, 12R, 15S, 18S, 21S, 24S, 30S, 33S)-. Grades: ≥90% by HPLC. CAS No. 89270-28-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
d 13223-d4(Flupirtine metabolite)
Heterocyclic Organic Compound. Alternative Names: N-[2-Amino-6-[[(4-fluorophenyl-d4)methyl]amino]-3-pyridinyl]acetamide Hydrochloride. CAS No. 1216989-17-1. Molecular formula: C14H12D4ClFN4O. Mole weight: 314.78. Appearance: White Solid. Purity: 0.96. IUPACName: N-[2-amino-6-[(2,3,5,6-tetradeuterio-4-fluorophenyl)methylamino]pyridin-3-yl]acetamide;hydrochloride. Canonical SMILES: CC (=O)NC1=C (N=C (C=C1)NCC2=CC=C (C=C2)F)N. Cl. Catalog: ACM1216989171.
D 13223-d4 (Flupirtine Metabolite)
The major active labeled metabolite of Flupirtine in human plasma. Group: Biochemicals. Alternative Names: N-[2-Amino-6-[[(4-fluorophenyl-d4)methyl]amino]-3-pyridinyl]acetamide Hydrochloride. Grades: Highly Purified. CAS No. 1216989-17-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
D 13223 (Flupirtine Metabolite)
The major active metabolite of Flupirtine in human plasma. Group: Biochemicals. Alternative Names: N-[2-Amino-6-[[ (4-fluorophenyl) methyl]amino]-3-pyridinyl]acetamide Hydrochloride. Grades: Highly Purified. CAS No. 95777-69-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Desmethyl Cerivastatin, Sodium Salt (M-21 Metabolite)
A metabolite of Cerivastatin, a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: M-21 Metabolite. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desmethyl Hydroxy Cerivastatin, Sodium Salt (M-24 Metabolite, Sodium (E)-7-(3R,5S)-{4-(4-Fluorophenyl)-6-[(S)-(hydroxymethyl)ethyl]-5-hydroxymethyl-2-isopropylpyrid-3-yl}-3,5dihydroxyhept-6-enoate)
A metabolite of Cerivastatin, a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: M-24 Metabolite, Sodium (E)-7-(3R,5S)-{4-(4-Fluorophenyl)-6-[(S)-(hydroxymethyl)ethyl]-5-hydroxymethyl-2-isopropylpyrid-3-yl}-3,5dihydroxyhept-6-enoate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
13C Labeled Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 2-[ (2, 6-Dichlorophenyl) amino]benzoic Acid; N- (2, 6-Dichlorophenyl) anthranilic Acid. Grades: Highly Purified. CAS No. 13625-57-5. Pack Sizes: 5mg. US Biological Life Sciences.
Dimethachlor Metabolite SYN 530561 is one of the metabolites of dimethachlor. Synonyms: 2-[(Hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid. CAS No. 1138220-18-4. Molecular formula: C13H17NO5. Mole weight: 267.28.
Docetaxel-d6 Metabolites M1 and M3 (Mixture of Diastereomers)
The major labeled metabolites 1 and 3 (diastereomers) of Docetaxel. Group: Biochemicals. Alternative Names: RPR 111026-d6. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Docetaxel Metabolite M4
The major human metabolite of Docetaxel , an antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 157067-34-0. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Docetaxel Metabolites M1 and M3 (Mixture of Diastereomers)
The major metabolites 1 and 3 (diastereomers) of Docetaxel. Group: Biochemicals. Alternative Names: RPR 111026. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Drug Metabolite/Impurity Library
A unique collection of 200 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS); - Structurally diverse, medicinally active, and cell permeable; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5800. Categories: Drug Metabolite/Impurity Libraries.
Erlotinib Hydroxy Metabolite
A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Hydroxy Erlotinib; N-(3-Ethynyl-4-hydroxy-phenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl] amine hydrochloride. Grades: > 95%. CAS No. 882420-22-6. Molecular formula: C22H23N3O5. Mole weight: 409.45.
Erlotinib metabolite M11
A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]acetic Acid. Grades: > 95%. CAS No. 882172-60-3. Molecular formula: C21H19N3O5. Mole weight: 393.40.
Erlotinib metabolite M12
A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-hydroxyethoxy)quinazoline; 2-(4-(3-Ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl)oxyethanol; 2-[4-(3-ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl]oxyethanol. CAS No. 183321-84-8. Molecular formula: C20H19N3O4. Mole weight: 365.389.
Erlotinib O-Desmethyl Metabolite Isomer
A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib 7-O-Desmethyl Metabolite; 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl] oxy]ethanol. Grades: > 95%. CAS No. 183320-29-8. Molecular formula: C21H21N3O4. Mole weight: 379.42.
Erlotinib O-Desmethyl Metabolite Isomer (M13)
Erlotinib O-Desmethyl Metabolite Isomer (M13). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((4-((3-ethynylphenyl)amino)-6-(2-methoxyethoxy)quinazolin-7-yl)oxy)ethanol. CAS No. 183320-29-8. Molecular Formula: C21H21N3O4. Mole Weight: 379.41. Catalog: APB183320298.
Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl
OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Synonyms: OSI420; OSI-420; OSI 420; CP473420; CP-473420; CP 473420; Desmethyl Erlotinib. Grades: > 95%. CAS No. 183320-51-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.874.
Esreboxetine Metabolite A
A metabolite of Esreboxetine. Esreboxetine is a selective norepinephrine reuptake inhibitor for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. Synonyms: 4-ethoxy-3-(2-morpholinylphenylmet?hoxy)?- Phenol. Grades: > 95%. CAS No. 140431-50-1. Molecular formula: C19H23NO4. Mole weight: 329.40.
Esreboxetine Metabolite B
A metabolite of Esreboxetine. Esreboxetine is a selective norepinephrine reuptake inhibitor for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. Synonyms: 3-ethoxy-4-(2-morpholinylphenylmet?hoxy)?- Phenol. Grades: > 95%. CAS No. 140431-51-2. Molecular formula: C19H23NO4. Mole weight: 329.40.
Esreboxetine Metabolite C
A metabolite of Esreboxetine. Esreboxetine is a selective norepinephrine reuptake inhibitor for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. Synonyms: 2-(morpholin-2-yl(phenyl)methoxy)phenol. Grades: > 95%. CAS No. 140431-52-3. Molecular formula: C17H19NO3. Mole weight: 285.35.
Etifoxine Metabolite
A metabolite of Etifoxine. Etifoxine is a positive allosteric modulator of GABA. Synonyms: 6-chloro-4-methyl-4-phenyl-1,4-dihydroquinazolin-2-ol. Grades: > 95%. Molecular formula: C15H13ClN2O. Mole weight: 272.74.
Exemestane Metabolite 1
A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane Sulfamate; (17β)-17-[(Aminosulfonyl)oxy]-6-methyleneandrosta-1,4-dien-3-one. Grades: > 95%. Molecular formula: C20H27NO4S. Mole weight: 377.51.
Exemestane Metabolite 2
A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Hydroxy-6-(methoxymethyl)-androsta-1,4-diene-3,17-dione. Grades: > 95%. Molecular formula: C21H28O4. Mole weight: 344.45.
A metabolite of Felodipine. Felodipine is a calcium channel blocker. Synonyms: 4-(2,3-dichlorophenyl)-5-(ethoxycarbonyl)-2-(hydroxymethyl)-6-methylnicotinic acid. Grades: > 95%. Molecular formula: C17H15Cl2NO5. Mole weight: 384.22.
Felodipine Metabolite Lactone
A metabolite of Felodipine. Felodipine is a calcium channel blocker. Synonyms: Furo[3,?4-b]?pyridine-3-carboxylic acid, 4-(2,?3-dichlorophenyl)?-1,?4,?5,?7-tetrahydro-2-methyl-5-oxo-, ethyl ester. Grades: > 95%. CAS No. 85825-42-9. Molecular formula: C17H13Cl2NO4. Mole weight: 366.20.
Fenamidone Metabolite
It is a metabolite of fennanone. Synonyms: (S)-5-Methyl-5-phenyl-3-phenylamino imidazoli-dine-2,4-dione. CAS No. 332855-88-6. Molecular formula: C16H15N3O2. Mole weight: 281.31.
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