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1- (3-Ethoxy-4-methoxy-phenyl) -2-methane sulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H. Group: Biochemicals. Grades: Highly Purified. CAS No. 253168-94-4. Pack Sizes: 250mg, 1g. Molecular Formula: C12H19NO4S, Molecular Weight: 273.35. US Biological Life Sciences.
1- (Difluoro methyl ) cyclopropane methane sulfonyl Chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 1780653-72-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C5H7ClF2O2S, Molecular Weight: 204.62. US Biological Life Sciences.
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1-Fluorocyclopropane methane sulfonyl Chloride
1-Fluorocyclopropane methane sulfonyl Chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 2044773-59-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C4H6ClFO2S, Molecular Weight: 172.61. US Biological Life Sciences.
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1-Octyl-3-methyl-1H-imidazolium bis[(trifluoromethyl)sulfonyl]methane salt
1-Octyl-3-methyl-1H-imidazolium bis[(trifluoromethyl)sulfonyl]methane salt. Uses: Designed for use in research and industrial production. Product Category: Imidazolium Ionic Liquids. CAS No. 916729-96-9. Molecular formula: C15H24F6N2O4S2. Mole weight: 474.48. Purity: ≥99%. Product ID: ACM916729969. Alfa Chemistry ISO 9001:2015 Certified.
1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose is a vital compound used in the biomedical industry. It exhibits potential therapeutic applications in the treatment of various diseases. Actively investigated for its efficacy, this compound displays promising results in the treatment of inflammatory disorders, cancer, and certain viral infections. Its unique molecular structure and bioactive properties make it a valuable component in drug research and development within the biomedicine field. Synonyms: 1,2-O-Isopropylidene-6-methyl-sulfonyl-alpha-D-glucofuranose; (R)-2-Hydroxy-2-((3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethyl methanesulfonate; (2R)-2-[(3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]-2-hydroxyethyl methanesulfonate. CAS No. 33557-25-4. Molecular formula: C10H18O8S. Mole weight: 298.31.
Used in the preparation of N-heterocyclic indole carboxamides as glycogen phosphorylase inhibitors. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-1,3-dioxolane-4-methanol 4-Methanesulfonate-d5; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl Methanesulfonate-d5; (±)-1,2-O-Isopropylidenepropane-1,2,3-triol 3-Mesylate-d5; DL-1-Methane sulfonylisopropyl idene glycerol-d5; Solketal Mesylate-d5. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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4-Methoxyriphenyl methyl chloride
4-Methoxyriphenyl methyl chloride is used in the synthesis of N-sulfonyl imines. Group: Biochemicals. Alternative Names: 1-(Chlorodiphenylmethyl)-4-methoxybenzene; p- (Chlorodiphenylmethyl) anisole; (p-Anisyl)diphenylmethyl Chloride; 1-(Chlorodiphenylmethyl)-4-methoxybenzene; 4-Anisyl (chloro) diphenylmethane; 4-Methoxytriphenylmethyl Chloride; 4-Methoxytritylchloride; 4-Monomethoxytrityl Chloride; MMTCl; Mono-p-methoxytrityl Chloride; NSC 54121; p- (Chlorodiphenylmethyl) anisole; p-Anisyl chlorodiphenyl methane ; p-Methoxytrityl Chloride. Grades: Highly Purified. CAS No. 14470-28-1. Pack Sizes: 5g. US Biological Life Sciences.
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4-Trifluoro methyl benzylsulfonyl chloride
4-Trifluoro methyl benzylsulfonyl chloride. Group: Biochemicals. Alternative Names: ([4- (Trifluoromethyl) phenyl]methyl) sulfonyl chloride; [4- (Trifluoromethyl) phenyl]methanesulfonyl chloride; 4-Trifluoromethyl-α-toluenesulfonyl chloride. Grades: Highly Purified. CAS No. 163295-75-8. Pack Sizes: 250mg, 500mg, 1g, 2g. US Biological Life Sciences.
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Adesulfone Sodium
Sulfoxone sodium is an anti-leprosy drug which was introduced in Japan in 1948. Uses: Leprosy. Synonyms: [Sulfonylbis(4,1-phenyleneimino)]bis-methanesulfinic Acid Disodium Salt; [Sulfonylbis(p-phenyleneimino)]di-methanesulfinic Acid Disodium Salt; Aldapsone; Aldesulfone Sodium; 4,4'-Sulfonylbis-benzenamine Bis(sodium formaldehydesulfonylate); Diamidin; Diason; Diasone; Diasone Sodium; Diazon; Disodium Formaldehydesulfoxylate-diaminodiphenyl Sulfone; NSC 27222; Novotrone; Sodium Aldesulphone; Sodium Sulfoxone; Sulfoxone Sodium; [Sulfonylbis(p-phenyleneimino)]dimethanesulfinic Acid, Disodium Salt; 144-76-3 (Sulfoxone free acid). Grade: 90%. CAS No. 144-75-2. Molecular formula: C14H14N2Na2O6S3. Mole weight: 448.45.
Almotriptan-d6 Malate
Almotriptan-d6 Malate is a labelled Almotriptan. Almotriptan is a triptan medication used for the treatment of acute headaches including migraine headache. Synonyms: 1-[[[2-(Dimethyl-amino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine Malate; 1-[[3-(2-dimethylaminoethyl)-5-indolyl]methanesulphonyl]pyrrolidine Malate-D6. Grade: > 95%. Molecular formula: C17H19N3O2SD6· C4H6O5. Mole weight: 475.6.
Almotriptan N,N-Didesmethyl
A metabolite of Almotriptan. Synonyms: 1-[[3-(2-Aminoethyl)-5-indolyl]methanesulfonyl]pyrrolidine; 1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine; 5-[(1-Pyrrolidinylsulfonyl)methyl]-1H-indole-3-ethanamine. Grade: > 95%. CAS No. 181178-24-5. Molecular formula: C15H21N3O2S. C4H6O5. Mole weight: 307.42.
Bis(vinylsulphonyl)methane
Bis(vinylsulphonyl)methane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1'-[methylenebis(sulfonyl)]bis-ethen;bis(vinylsulphonyl)methane;1,1'-[methylenebis(sulfonyl)]bisethene;BIS(VINYLSULFONYL)METHANE;1,1'-[methylenebis(sulphonyl)]diethylene;11METHYLENEBISSULPHONYLBISETHENE;BIS(VINYLSULFONE)METHANE;Methylenebis(vinyl sulfo. Product Category: Heterocyclic Organic Compound. CAS No. 3278-22-6. Molecular formula: C5H8O4S2. Mole weight: 196.23. Purity: 0.99. Density: 1.369g/cm³. Product ID: ACM3278226. Alfa Chemistry ISO 9001:2015 Certified.
Camphorquinone-10-sulfonyl chloride
Camphorquinone-10-sulfonyl chloride. Group: Biochemicals. Alternative Names: 7,7-Dimethyl-2,3-dioxo-bicyclo[2.2.1]heptane-1-methanesulfonyl chloride. Grades: Highly Purified. CAS No. 82594-19-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C10H13ClO4S. US Biological Life Sciences.
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CB2R-IN-1
CB2R-IN-1 is a potent inverse agonist of cannabinoid CB2 receptor with a Ki of 0.9 nM. Synonyms: 1,1,1-Trifluoro-N-[[4-propyl-1-[[1-(2-pyridinylsulfonyl)-1H-indol-2-yl]sulfonyl]-4-piperidinyl]methyl]methanesulfonamide; Methanesulfonamide, 1,1,1-trifluoro-N-[[4-propyl-1-[[1-(2-pyridinylsulfonyl)-1H-indol-2-yl]sulfonyl]-4-piperidinyl]methyl]-. Grade: ≥97%. CAS No. 1257555-79-5. Molecular formula: C23H27F3N4O6S3. Mole weight: 608.67.
Almotriptan metabolite. Group: Biochemicals. Alternative Names: 1- [ [3- (2-Aminoethyl) -5-indolyl] methanesulfonyl] pyrrolidine; 1- [ [ [3- (2-Aminoethyl) -1H-indol-5-yl] methyl] sulfonyl] pyrrolidine; 5-[ (1-Pyrrolidinylsulfonyl) methyl]-1H-indole-3-ethanamine. Grades: Highly Purified. CAS No. 181178-24-5. Pack Sizes: 5mg. US Biological Life Sciences.
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Dimethyl sulfone
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 67-71-0. Pack Sizes: 5 g; 10 g. Product ID: HY-Y1314.
Dimethyl Sulfone
Dimethyl Sulfone, is a dietary supplement, presenting in small amounts in many foods and beverages. It can be used as as a high-temperature solvent for both inorganic and organic substances, due to its polarity and thermal stability. It has been also shown to be used for the treatment of Osteoarthritis, in combination with other compounds. Group: Biochemicals. Alternative Names: 1,1-Sulfonylbis-methane; Sulfonylbis-methane; Dimethyl Sulphone; Lignisul MSM; MSM; Methylsulfonylmethane; NSC 63345; Opti MSM; Opti-dimethyl Sulfone. Grades: Highly Purified. CAS No. 67-71-0. Pack Sizes: 500g, 1Kg. Molecular Formula: C?H?O?S, Molecular Weight: 94.13. US Biological Life Sciences.
N-(4-tert-Butylphenyl)bis(trifluoromethanesulfonimide). Uses: Designed for use in research and industrial production. Additional or Alternative Names: AGN-PC-00PUGC, N-(4-tert-Butylphenyl)bis(trifluoromethanesulfonimide), N-(4-tert-Butylphenyl) bis-trifluoromethane sulfonimide, N-(4-tert-butylphenyl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide, 121287-02-3, N-[4-(1,1-Dimethylethyl)phenyl]-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-methanesulfonamide. Product Category: Heterocyclic Organic Compound. CAS No. 121287-02-3. Molecular formula: C12H13F6NO4S2. Mole weight: 413.36. Purity: 0.96. IUPACName: N-(4-tert-butylphenyl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide. Canonical SMILES: CC(C)(C)C1=CC=C(C=C1)N(S(=O)(=O)C(F)(F)F)S(=O)(=O)C(F)(F)F. Product ID: ACM121287023. Alfa Chemistry ISO 9001:2015 Certified.
N,N-Bis(trifluoromethylsulfonyl)aniline
N,N-Bis(trifluoromethylsulfonyl)aniline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: phenyltrifluoromethanesulfonimide;1,1,1-TRIFLUORO-N-PHENYL-N-[(TRIFLUOROMETHYL)SULFONYL]METHANESULFONAMIDE;N-PHENYLBIS(TRIFLUOROMETHANESULFONIMIDE);N-PHENYLBIS(TRIFLUOROMETHANESULPHONIMIDE);N-PHENYLTRIFLUOROMETHANESULFONIMIDE;N-PHENYLTRIFLUOROMETHANESULPHONIMIDE;N,N-BIS(TRIFLUOROMETHYLSULFONYL)ANILINE;PHENYL TRIFLIMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 37595-74-7. Molecular formula: C8H5F6NO4S2. Mole weight: 357.25. Product ID: ACM37595747. Alfa Chemistry ISO 9001:2015 Certified.
N-Phenyl-bis(trifluoromethanesulfonimide). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1,1-Trifluoro-N-phenyl-N-[(trifluoromethyl)sulfonyl]methanesulfonamide, N,N-Bis(trifluoromethylsulfonyl)aniline, N-Phenyl-trifluoromethanesulfonimide, NSC 240874, Phenyl triflimide. Product Category: Sulfonylation Reagents. CAS No. 37595-74-7. Molecular formula: C8H5F6NO4S2. Mole weight: 357.2422. Purity: 0.97. Product ID: ACM37595747-1. Alfa Chemistry ISO 9001:2015 Certified.
Dual -acting peroxisome proliferator-activated receptor (PPAR) α and γ agonist. Antidiabetic. Group: Biochemicals. Alternative Names: (α S) -α -Ethoxy-4- [2- [4- [ (methylsulfonyl) oxy] phenyl] ethoxy] benzenepropanoic Acid; (S) -2-Ethoxy-3- [4- [2- (4-methane sulfonyloxyphenyl) ethoxy] phenyl] propanoic Acid;AR-H 039242; AR-H 039242XX; AZ 242; Galida. Grades: Highly Purified. CAS No. 251565-85-2. Pack Sizes: 10mg. US Biological Life Sciences.
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13-{[ (3-tert-Butyloxycarbonyl) -2, 2-dimethyl-4S-phenyl-1, 3-oxazolidin-5R-yl]formyl}-7-O- ( (trifluoromethyl) sulfonyl]oxy) Baccatin III
Intermediate in the synthesis of taxol analogs. Group: Biochemicals. Alternative Names: (4S, 5R) -2, 2-Di methyl -4-phenyl -3, 5-oxazolidinedicarboxyl ic Acid 5-[ (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS) -6, 12b-Bis (acetyloxy) -12- (benzoyloxy) -2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[[ (trifluoromethyl) sulfonyl]oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester. Grades: Highly Purified. CAS No. 168120-69-2. Pack Sizes: 10mg. US Biological Life Sciences.
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(1S)-(-)-(7,7-Dichloro-10-camphorsulfonyl)imine
A useful synthetic intermediate. used in the synthesis of (+) -[ (8, 8-Dichlorocamphoryl) sulfonyl]oxaziridine. Group: Biochemicals. Alternative Names: (3aS,6S)-7,7-Dichloro-4,5,6,7-tetrahydro-8,8-dimethyl-3H-3a,6-methano-2,1-benzisothiazole 2,2-Dioxide. Grades: Highly Purified. CAS No. 127184-04-7. Pack Sizes: 250mg. US Biological Life Sciences.
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1-Tosy-3-(1-naphthoyl)pyrrole
1-Tosy-3-(1-naphthoyl)pyrrole. Group: Biochemicals. Alternative Names: [1-[(4-Methylphenyl)sulfonyl]-1H-pyrrol-3-yl]-1-naphthalenyl-methanone; 1-[(4-Methylphenyl)sulfonyl]-3-(1-naphthalenylcarbonyl)-1H-pyrrole. Grades: Highly Purified. CAS No. 129667-10-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C22H17NO3S. US Biological Life Sciences.
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1-Tosyl-3-(1-naphthoyl)pyrrole
Used in the preparation of 1-alkyl-3-(1-naphthoyl)pyrroles, a new class of cannabinoid. Group: Biochemicals. Alternative Names: [1-[(4-Methylphenyl)sulfonyl]-1H-pyrrol-3-yl]-1-naphthalenyl-methanone; 1-[(4-Methylphenyl)sulfonyl]-3-(1-naphthalenylcarbonyl)-1H-pyrrole. Grades: Highly Purified. CAS No. 129667-10-3. Pack Sizes: 100mg. US Biological Life Sciences.
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5-Hydroxy Omeprazole-d3 Sulfone
A metabolite of Omeprazole, which is a proton pump inhibitor used in the treatment of dyspepsia. Synonyms: (4-methoxy-6-(((5-methoxy-1H-benzo[d]imidazol-2-yl)sulfonyl)methyl)-5-methylpyridin-3-yl)methanol-d3. Grade: > 95%. Molecular formula: C17H16D3NO5S. Mole weight: 380.44.
Oxidizing reagent. Group: Biochemicals. Alternative Names: [2R-(2α, 4aα, 7α, 8aR*)]-8, 8-Dichlorotetrahydro-9, 9-dimethyl-4H-4a, 7-methanooxazirino[3, 2-i][2, 1]benzisothiazole 3,3-Dioxide. Grades: Highly Purified. CAS No. 127184-05-8. Pack Sizes: 100mg. US Biological Life Sciences.
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A01
A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM), which attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Study showed that it potentiated BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells. Synonyms: Smurf1-IN-A01; Smurf1INA01; Smurf1 IN A01; Smurf1 inhibitor A01; Smurf1-inhibitor-A01; A01; A 01; A-01; [4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone; SMURF1 inhibitor A01. Grade: ≥98% by HPLC. CAS No. 1007647-73-5. Molecular formula: C22H20ClF3N4O3S. Mole weight: 512.93.
Abeprazan
Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is used for the treatment of 5-HT receptor or muscarinic acetylcholine receptor-mediated diseases. Synonyms: Fexuprazan; 5-(2,4-Difluorophenyl)-1-[(3-fluorophenyl)sulfonyl]-4-methoxy-N-methyl-1H-pyrrole-3-methanamine; DWP14012; DWP-14012. Grade: 99%. CAS No. 1902954-60-2. Molecular formula: C19H17F3N2O3S. Mole weight: 410.41.
CDK5-IN-1
CDK5-IN-1 is a potent CDK5 inhibitor with an activity of less than 10 nM against CDK5. It is used in kidney diseases research. Synonyms: 1H-Pyrazole-3-methanol, 1-[3-fluoro-4-[[2-[(1-methyl-4-piperidinyl)sulfonyl]-1,6-naphthyridin-7-yl]amino]phenyl]-. CAS No. 2639540-19-3. Molecular formula: C24H25FN6O3S. Mole weight: 496.56.
CNV-2197944
CNV-2197944, a selective, state-dependent Cav2.2 calcium channel blocker, can reverse hyperalgesia associated with injury or inflammation in conjunction with the opioid. (Extracted from patent WO2017046581A1, compound 1). Synonyms: Cav 2.2 blocker 2; CNV2197944; Methanone, (2-methyl-3-pyridinyl)((2S)-2-methyl-4-((4-(trifluoromethyl)phenyl)sulfonyl)-1-piperazinyl)-; (S)-(2-Methyl-4-((4-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)(2-methylpyridin-3-yl)methanone. Grade: ≥98%. CAS No. 1204535-44-3. Molecular formula: C19H20F3N3O3S. Mole weight: 427.44.
Dazucorilant
Dazucorilant is a glucocorticoid receptor antagonist. Synonyms: {(4aR)-1-(4-fluorophenyl)-6-[4-(trifluoromethyl)benzene-1-sulfonyl]-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl}(pyridin-2-yl)methanone; (R)-(1-(4-fluorophenyl)-6-((4-(trifluoromethyl)phenyl)sulfonyl)-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl)(pyridin-2-yl)methanone. CAS No. 1496508-34-9. Molecular formula: C29H22F4N4O3S. Mole weight: 582.58.
Defluoro Tosyloxy AM-694
Intermediate in the preparation of AM-694. Group: Biochemicals. Alternative Names: (2-Iodophenyl) [1-[5-[[ (4-methylphenyl) sulfonyl]oxy]pentyl]-1H-indol-3-yl]-methanone. Grades: Highly Purified. CAS No. 335160-96-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
glecaprevir
Glecaprevir is a suppressive agent of hepatitis C virus (HCV). Glecaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 4.09 μM. Uses: The treatment of hepatitis c virus (hcv) infection. Synonyms: ABT 493; (3aR,7S,10S,12R,21E,24aR)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-20,20-difluoro-5,8-dioxo-2,3,3a,5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12-methanocyclopenta[18,19][1,10,17,3,6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide. Grade: 98%. CAS No. 1365970-03-1. Molecular formula: C38H46F4N6O9S. Mole weight: 838.87.
Naringin
Naringin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Naringenin 7-Rhamnoglucoside Hydrate; Naringin Hydrate; Naringenin 7-neohesperidoside; Naringenoside; Nobiletin. Product Category: Heterocyclic Organic Compound. Appearance: beige to yellowish powder. CAS No. 10236-47-6. Molecular formula: C37H39FN2O6S. Mole weight: 658.778763;g/mol. Purity: 0.96. IUPACName: (4-fluoronaphthalen-1-yl)-[4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]methanone. Canonical SMILES: COC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C3(OCCO3)C4CCN(CC4)C5CCN(CC5)C(=O)C6=CC=C(C7=CC=CC=C76)F. Density: 1.66 g/cm³. Product ID: ACM10236476. Alfa Chemistry ISO 9001:2015 Certified.
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