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Methotrexate meets USP testing specifications. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Methotrexate Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amethopterin; CL14377; WR19039. CAS No. 59-05-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14519. MedChemExpress MCE
Methotrexate Methotrexate. Uses: Antitumor drugs. Additional or Alternative Names: METHOTREXATE;METHYLAMINOPTERIN;METHYLAMINOPTERINE;ANTIFOLAN;L-(+)-AMETHOPTERIN;4-AMINO-N 10-METHYLPTEROYL-L-GLUTAMIC ACID;4-AMINO-10-METHYLPTEROYLGLUTAMIC ACID;(+)-4-AMINO-10-METHYLFOLIC ACID. Product Category: Heterocyclic Organic Compound. Appearance: powder. CAS No. 59-05-2. Molecular formula: C20H22N8O5. Mole weight: 454.44. Product ID: ACM59052. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
Methotrexate Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. Uses: Adcs cytotoxin. Synonyms: WR19039; CL14377; WR 19039; WR-19039; CL 14377; CL-14377. Grade: >98%. CAS No. 59-05-2. Molecular formula: C20H22N8O5. Mole weight: 454.44. BOC Sciences 2
Methotrexate Pharmaceutical Secondary Standard; Certified Reference Material. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Methotrexate United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: L-Amethopterin, 4-Amino-N10-methylfolic acid, Ledertrexate, 4-Amino-10-methylfolic acid, NSC 740, CL 14377, Antifolan, Methoxtrexate, Methylaminopterin, L-(+)-N-[p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-glutamic acid, Metatrexan, N-[p-[[2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-(+)-glutamic acid, Amethopterine, 4-Amino-N10-methylpteroylglutamic acid, Methotrexate, R 9985, Methotrexat-Ebewe, Amethopterin, EMT 25299, MTX, Rheumatrex, Trexall, (+)-Amethopterin, Mexate, Emtexate,N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid, L-Methotrexate. Alfa Chemistry Analytical Products
Methotrexate?Agarose saline suspension. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Methotrexate α-Methyl Ester Methotrexate α-Methyl Ester. Group: Biochemicals. Alternative Names: N- [4- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoyl] -L-glutamic Acid 1-Methyl Ester. Grades: Highly Purified. CAS No. 66147-29-3. Pack Sizes: 10mg. Molecular Formula: C21H24N8O5, Molecular Weight: 468.47. US Biological Life Sciences. USBiological 3
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Methotrexate ((+)-Amethopterin, 4-Amino-10-methylpteroylglutamic Acid, Methylaminopterin, 4-Amino-10-methylfolic acid, MTX) Methotrexate is a folic acid antagonist and is classified medically as an antineoplastic and antirheumatic agent. Group: Biochemicals. Alternative Names: (+)-Amethopterin; Methylaminopterin; 4-Amino-10-methylfolic acid. Grades: Molecular Biology Grade. CAS No. 59-05-2. Pack Sizes: 100mg, 500mg, 1g. US Biological Life Sciences. USBiological 1
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Methotrexate-Cadaverine-Biotin Conjugate Methotrexate-Cadaverine-Biotin Conjugate is a biotin labelled Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Synonyms: N2-(4-{[(2,4-Diamino-6-pteridinyl)methyl](methyl)amino}benzoyl)-N-[5-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)pentyl]-L-glutamine; L-Glutamine, N2-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-N-[5-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]pentyl]-. Grade: 95%. Molecular formula: C35H48N12O6S. Mole weight: 764.90. BOC Sciences
Methotrexate-d3 Methotrexate-d3 is the deuterated version of Methotrexate. Methotrexate (Amethopterin) is an antimetabolite and antifolate that inhibits dihydrofolate reductase, which prevents the conversion of folate to tetrahydrofolate and inhibits DNA synthesis. Methotrexate is also an immunosuppressant and antineoplastic agent used in rheumatoid arthritis and researched in various cancers (such as acute lymphoblastic leukemia). Synonyms: Methotrexate-d3; Methotrexate-d3, Technical Grade 85per cent; (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-(trideuteriomethyl)amino]benzoyl]amino]pentanedioic acid; L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methyl-d3-amino]benzoyl]-(9ci). Grade: 95% by HPLC; 95% atom D. CAS No. 432545-63-6. Molecular formula: C20H19D3N8O5. Mole weight: 457.46. BOC Sciences 2
Methotrexate-d3 Heptaglutamate Methotrexate-d3 Heptaglutamate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C50H61D3N14O23, Molecular Weight: 1232.142. US Biological Life Sciences. USBiological 3
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Methotrexate-D3 solution 100 ?g/mL in methanol with 0.01N NaOH, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
Methotrexate Dimethyl Ester Methotrexate Dimethyl Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. USBiological 1
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Methotrexate Dimethyl Ester Methotrexate Dimethyl Ester. Uses: For analytical and research use. Group: Impurity standards. CAS No. 34378-65-9. Pack Sizes: 100MG. IUPAC Name: dimethyl (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate. Molecular formula: C22H26N8O5. Mole weight: 482.49. Catalog: APS34378659. SMILES: COC(=O)CC[C@H](NC(=O)c1ccc(cc1)N(C)Cc2cnc3nc(N)nc(N)c3n2)C(=O)OC. Format: Neat. Shipping: Room Temperature. Alfa Chemistry Analytical Products 4
Methotrexate Dimethyl Ester-[d3] Methotrexate Dimethyl Ester-[d3]. Synonyms: Methotrexate-d3 Dimethyl Ester. Grade: 95% atom D. CAS No. 432545-60-3. Molecular formula: C22H23D3N8O5. Mole weight: 485.51. BOC Sciences 2
Methotrexate disodium Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia)[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amethopterin disodium; CL14377 disodium; WR19039 disodium. CAS No. 7413-34-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14519A. MedChemExpress MCE
Methotrexate γ-Methyl Ester Methotrexate γ-Methyl Ester. Group: Biochemicals. Alternative Names: N- [4- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoyl] -L-glutamic Acid 5-Methyl Ester. Grades: Highly Purified. CAS No. 67022-39-3. Pack Sizes: 100mg. Molecular Formula: C21H24N8O5, Molecular Weight: 468.47. US Biological Life Sciences. USBiological 3
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Methotrexate Heptaglutamate Methotrexate Heptaglutamate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C50H64N14O23, Molecular Weight: 1229.13699999999. US Biological Life Sciences. USBiological 3
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Methotrexate hydrate Methotrexate hydrate is a substance that affects cell growth and division. It is commonly used to fight certain diseases, especially cancer and autoimmune diseases. It works by inhibiting the process by which cells synthesize DNA. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Amethopterin hydrate; CL14377 hydrate; WR19039 hydrate. CAS No. 133073-73-1. Pack Sizes: 1 g; 5 g. Product ID: HY-14519B. MedChemExpress MCE
Methotrexate Impurity 25 Methotrexate Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-methylaminobenzoic acid. CAS No. 10541-83-0. Molecular formula: C8H9NO2. Mole weight: 151.17. Catalog: APB10541830. Alfa Chemistry Analytical Products 4
Methotrexate impurity 29 Methotrexate impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1004-38-2. Molecular formula: C4H7N5. Mole weight: 125.14. Catalog: APB1004382. Alfa Chemistry Analytical Products 4
Methotrexate-(methyl-13C,d3) analytical standard. Group: Additional drugs. Alfa Chemistry Analytical Products
Methotrexate-methyl-d3 ((+)-Amethopterin-methyl-d3, 4-Amino-10-methylpteroylglutamic-methyl-d3 Acid) Deuterated Methotrexate an antineoplastic and antirheumatic. A folic Acid antagonist. Group: Biochemicals. Alternative Names: (+)-Amethopterin-methyl-d3, 4-Amino-10-methylpteroylglutamic-methyl-d3 Acid. Grades: Highly Purified. Pack Sizes: 500ug, 1mg, 5mg. US Biological Life Sciences. USBiological 1
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Methotrexate-methyl-d3, Dimethyl Ester Methotrexate-methyl-d3, Dimethyl Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 1
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Methotrexate Related Compound B United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Methotrexate Related Compound C United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Methotrexate Related Compound E United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Methotrexate solution 1.0 mg/mL in methanol with 0.1N NaOH, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
Methotrexate System Suitability Mixture United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products
Methotrexate tetraglutamate Methotrexate tetraglutamate. Group: Biochemicals. Grades: Highly Purified. CAS No. 73610-81-8. Pack Sizes: 5mg, 10mg, 20mg. Molecular Formula: C35H43N11O14. US Biological Life Sciences. USBiological 8
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Methotrexate Triglutamate-[d7] Methotrexate Triglutamate-[d7] is the labelled analogue of Methotrexate Triglutamate, which is a metabolite of Methotrexate. Methotrexate is a chemotherapy agent and immunosuppressive agent. It can be used to treat cancer, autoimmune diseases, ectopic pregnancies and medical abortions. Synonyms: Methotrexate D7 Triglutamate; N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-γ-glutamyl-L-γ-glutamyl-L-glutamic Acid-d7; 4-Amino-10-methylpteroylglutamyl-γ-diglutamic Acid-d7; MTXPG3-d7; NSC 341076-d7. Grade: 95% by HPLC; 98% atom D. Molecular formula: C30H29D7N10O11. Mole weight: 719.71. BOC Sciences 2
7-Cyanomethotrexate Dimethyl Ester 7-Cyanomethotrexate Dimethyl Ester is an intermediate of Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Uses: An intermediate in the production of methotrexate metabolites. Synonyms: N-[4-[[(2,4-Diamino-7-cyano-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid Dimethyl Ester; Dimethyl N-(4-{[(2,4-diamino-7-cyano-6-pteridinyl)methyl](methyl)amino}benzoyl)-L-glutamate; L-Glutamic acid, N-[4-[[(2,4-diamino-7-cyano-6-pteridinyl)methyl]methylamino]benzoyl]-, dimethyl ester; (S)-Dimethyl 2-(4-(((4-amino-7-cyano-2-imino-2,3-dihydropteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate. Grade: 98%. CAS No. 112163-39-0. Molecular formula: C23H25N9O5. Mole weight: 507.50. BOC Sciences 5
7-Hydroxymethotrexate 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5939-37-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-130569. MedChemExpress MCE
7-Hydroxy Methotrexate 7-Hydroxy Methotrexate is a metabolite of Methotrexate, which is used as an antineoplastic and antirheumatic. Uses: Folic acid antagonists. Synonyms: Methotrexate 7-Hydroxy Metabolite; 7-Hydroxy Amethopterin; (4-(((2,4-Diamino-7-hydroxypteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic Acid. Grade: 95%. CAS No. 5939-37-7. Molecular formula: C20H22N8O6. Mole weight: 470.44. BOC Sciences 5
7-Hydroxy Methotrexate A metabolite of Methotrexate, which is used as a antineoplastic and antirheumatic. Group: Biochemicals. Alternative Names: 7-Hydroxy amethopterin, 4-amino-7-hydroxy-10-methylpteroylglutamic acid; N- [4- [ [ (2, 4-Diamino-7, 8-dihydro-7-oxo-6-pteridinyl) methyl] methylamino] benzoyl] -L-glutamic acid; NSC 380962. Grades: Highly Purified. CAS No. 5939-37-7. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 470.44. US Biological Life Sciences. USBiological 7
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7-Hydroxy Methotrexate Ammonium Salt 7-Hydroxy Methotrexate Ammonium Salt is one of methotrexate metabolites. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: Ammonium (S)-4-carboxy-2-(4-(((2,4-diamino-7-hydroxypteridin-6-yl)methyl)(methyl)amino)benzamido)butanoate; NSC380963; NSC-380963; 7-Hydroxymethotrexate Ammonium Salt. Grade: 97%. Molecular formula: C20H25N9O6. Mole weight: 487.47. BOC Sciences 5
7-Hydroxy Methotrexate-d3 (7-Hydroxy Amethopterin-d3 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid-d3) A deuterated metabolite of Methotrexate, which is used as a antineoplastic and antirheumatic. Group: Biochemicals. Alternative Names: 7-Hydroxy Amethopterin-d3 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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7-Hydroxy Methotrexate-d3 Ammonium Salt 7-Hydroxy Methotrexate-d3 is a deuterated metabolite of Methotrexate, which is used as a antineoplastic and antirheumatic. Grade: > 95%. Molecular formula: C20H22N9O6D3. Mole weight: 490.49. BOC Sciences 5
7-Hydroxy Methotrexate Trisodium Salt 7-Hydroxy Methotrexate Trisodium Salt is one of methotrexate impurities. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Molecular formula: C20H19N8O6.3Na. Mole weight: 536.38. BOC Sciences 5
DL-Methotrexate DL-Methotrexate. Group: Biochemicals. Alternative Names: N- [4- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoyl] -glutamic Acid; DL-Amethopterin; DL-Methotrexate; NSC 117356. Grades: Highly Purified. CAS No. 60388-53-6. Pack Sizes: 25mg. Molecular Formula: C20H22N8O5, Molecular Weight: 454.44. US Biological Life Sciences. USBiological 3
Worldwide
DL-Methotrexate-d3 DL-Methotrexate-d3. Group: Biochemicals. Alternative Names: N- [4- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoyl] -glutamic Acid-d3; DL-Amethopterin-d3; NSC 117356-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H19D3N8O5, Molecular Weight: 457.46. US Biological Life Sciences. USBiological 3
Worldwide
DL-Methotrexate-d3 Dipotassium Salt Isotope Labelled analogue of Racemic Methotrexate, a folic acid antagonist. Act as an antineoplastic and antirheumatic. Synonyms: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-glutamic Acid-d3 Dipotassium Salt; DL-Amethopterin-d3 Dipotassium Salt; NSC 117356-d3 Dipotassium Salt. Molecular formula: C20H17D3K2N8O5. Mole weight: 533.64. BOC Sciences 7
DL-Methotrexate Dipotassium Salt Dihydrate DL-Methotrexate Dipotassium Salt Dihydrate is a racemic form of Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Synonyms: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-glutamic Acid Dipotassium Salt Dihydrate; DL-Amethopterin; Dipotassium Salt Dihydrate; DL-Methotrexate Dipotassium Salt Dihydrate; NSC 117356 Dipotassium Salt Dihydrate. Molecular formula: C20H24K2N8O7. Mole weight: 566.65. BOC Sciences 7
Folic Acid EP Impurity A (Methotrexate EP Impurity K) An impurity of Methotrexate, an antimetabolite and immunosuppressant used in chemotherapy and auto-immune diseases. Synonyms: 4-Aminobenzoylglutamic Acid (USP); N-(4-Aminobenzoyl)-L-glutamic Acid; N-(p-Aminobenzoyl)glutamic Acid; N-(p-Aminobenzoyl)-L(+)-glutamic Acid. Grade: > 95%. CAS No. 4271-30-1. Molecular formula: C12H14N2O5. Mole weight: 266.25. BOC Sciences 8
Folic Acid EP Impurity D (Methotrexate EP Impurity D) Pteroic Acid is one of methotrexate impurities. Methotrexate is a folic acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: Pteroic acid; Pyrofolic acid; p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic Acid. Grade: > 85 %. CAS No. 119-24-4. Molecular formula: C14H12N6O3. Mole weight: 312.28. BOC Sciences 8
L-(+)-Amethopterin hydrate (Methotrexate) 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C20H22N8O5. CAS No. 59-05-2. Prepack ID 30186373-100mg. Molecular Weight 454.44. See USA prepack pricing. Molekula Americas
N-(5-Aminopentyl) methotrexate amide N-(5-Aminopentyl) methotrexate amide. Group: Biochemicals. Alternative Names: N- (5-Aminopentyl) -N2- [4- [ [ (2, 4-diamino-6-pteridinyl) methyl] methylamino] benzoyl] -L-glutamine; MTX-DAP. Grades: Highly Purified. CAS No. 136672-64-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C25H34N10O4. US Biological Life Sciences. USBiological 6
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N-(5-Aminopentyl) methotrexate amide-LC-biotin N-(5-Aminopentyl) methotrexate amide-LC-biotin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences. USBiological 6
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R-Methotrexate United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
(R)-Methotrexate-d3 (R)-Methotrexate-d3 is an isotopically labelled form of (R)-Methotrexate. It is an enantiomer of Methotrexate, a folic acid antagonist. It can be used as an antineoplastic and antirheumatic. Synonyms: D-Amethopterin-d3; D-Methotrexate-d3; N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-D-glutamic Acid-d3. Grade: 0.95. Molecular formula: C20H19D3N8O5. Mole weight: 457.46. BOC Sciences 3
(R)-Methotrexate N,N-dimethylamide (R)-Methotrexate N,N-dimethylamide is one of methotrexate impurities. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Molecular formula: C22H27N9O4. Mole weight: 481.51. BOC Sciences 3
(R/S)-Methotrexate N,N-dimethylamide (R/S)-Methotrexate N,N-dimethylamide is one of methotrexate impurities. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Molecular formula: C22H27N9O4. Mole weight: 481.51. BOC Sciences 3
2,4,5,6-Tetraaminopyrimidine Sulfate Intermediate in the production of Methotrexate. Group: Biochemicals. Alternative Names: 2,4,5,6-Pyrimidinetetramine Sulfate; NSC 227862; NSC 3277. Grades: Highly Purified. CAS No. 5392-28-9. Pack Sizes: 10g. US Biological Life Sciences. USBiological 3
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2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride is one of methotrexate intermediates. Methotrexate is a Folic Acid antagonist, used as a antineoplastic and antirheumatic. Uses: Methotrexate intermediate. Synonyms: 2,4-Diaminopyrimido[4,5-b]pyrazine-6-methanol Monohydrochloride; 4-Diamino-6-pteridinemethanol Hydrochloride. Grade: 95%. CAS No. 73978-41-3. Molecular formula: C7H9ClN6O. Mole weight: 228.64. BOC Sciences 3
2-(Bromomethyl)acrylic Acid 2-(Bromomethyl)acrylic Acid. Uses: Reacts with aldehydes and ketones to form α-methylene-butyrolactones. used in the synthesis of methotrexate analogues. Additional or Alternative Names: 2-(bromomethyl)-2-propenoic acid; 2-(bromomethyl)prop-2-enoic acid. Product Category: Polymer/MacromoleculeAcrylate Monomers. Appearance: Beige Crystalline Solid. CAS No. 72707-66-5. Molecular formula: C4H5BrO2. Mole weight: 164.99 g/mol. Purity: 0.98. Canonical SMILES: OC(=O)C(=C)CBr. ECNumber: 276-774-0. Product ID: ACM-MO-72707665. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
(2S) -2- (4- (4- ( ( (2, 4-diaminopteridin-6-yl) methyl) (methyl) amino) -N-methylbenzamido) benzamido) pentanedioic Acid (2S) -2- (4- (4- ( ( (2, 4-diaminopteridin-6-yl) methyl) (methyl) amino) -N-methylbenzamido) benzamido) pentanedioic Acid is an impurity of Methotrexate (M260675) which is a Folic acid antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C28H29N9O6, Molecular Weight: 587.59. US Biological Life Sciences. USBiological 10
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(2S)-2-(4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)-N-methylbenzamido)benzamido)pentanedioic Acid (2S)-2-(4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)-N-methylbenzamido)benzamido)pentanedioic Acid is one of methotrexate impurities. Methotrexate is a Folic Acid antagonist, used as an antineoplastic and antirheumatic. Synonyms: Methotrexate Impurity G; Methotrexate EP Impurity G. Molecular formula: C28H29N9O6. Mole weight: 587.59. BOC Sciences 3
(4-(((2,4-Diaminopteridin-6-yl)methyl)amino)benzoyl)glutamic acid hydrate An impurity of Methotrexate, an antimetabolite and immunosuppressant used in chemotherapy and auto-immune diseases. Grade: 95%. CAS No. 1217459-90-9. Molecular formula: C19H22N8O6. Mole weight: 458.4. BOC Sciences 3
4-Amino-N10-methylpteroyl-L-glutamic acid 4-Amino-N10-methylpteroyl-L-glutamic acid. Group: Biochemicals. Alternative Names: N- [4- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoyl] -L-glutamic acid; Methotrexate. Grades: Highly Purified. CAS No. 59-05-2. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C20H22N8O5. US Biological Life Sciences. USBiological 6
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4-Fluoro-DL-glutamic Acid 4-Fluoro-DL-glutamic acid is used as a reagent to synthesize analogues of Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Synonyms: 4-Fluoroglutamic Acid; 4-Fluoroglutamic Acid; DL-4-Fluoroglutamic Acid; 2-Amino-4-fluoropentane-1,5-dioic acid; 4-Fluoro-Glutamic Acid; threo-4-fluoroglutamic acid; D,L-erythro,threo-4-fluoroglutamic acid. Grade: ≥95%. CAS No. 2708-77-2. Molecular formula: C5H8FNO4. Mole weight: 165.12. BOC Sciences 4
(±)-Amethopterin (±)-Amethopterin is a folic acid antagonist used as an anticancer agent. Synonyms: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]glutamic Acid; (±)-Methotrexate; DL-Amethopterin; DL-Methotrexate; NSC 117356; Methotrexate Impurity 3; amethopterin; 4-amino-N10-methylpteroylglutamic acid; D-methionine-R-sulfoximine. Grade: 98%. CAS No. 60388-53-6. Molecular formula: C20H22N8O5. Mole weight: 454.44. BOC Sciences 2
Calcium Folinate Pentahydrate When administered after methotrexate, supplies cells with tetrahydrofolate and diminishes methotrexate toxicity without abolishing the antitumor effect. Group: Biochemicals. Alternative Names: 5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt’ Leucovorin. Grades: Highly Purified. CAS No. 41927-89-3. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C20H21CaN7O7·5H2O, Molecular Weight: 601.58. US Biological Life Sciences. USBiological 6
Worldwide
CHS-828 CHS-828 is a synthetic guanidine-based small anticancer molecule. CHS 828 was found to exert potent cytotoxic effects in human breast and lung cancer cell lines, with lesser effects on normal fibroblasts and endothelial cells. In nude mice bearing human tumor xenografts, CHS 828, at doses from 20 to 50 mg/kg/day p.o., inhibited the growth of MCF-7 breast cancer tumors and caused regression of NYH small cell lung cancer tumors. Oral administration of CHS 828 once weekly improved efficacy without increasing toxicity. CHS 828 was found to compare favorably with established chemotherapeutic agents such as cyclophosphamide, etoposide, methotrexate, and paclitaxel. In mice with NYH tumors, long-term survival (>6 months) was observed after treatment with CHS 828 was stopped. CHS 828 is an effective new antitumor agent, with a potentially new mechanism of action. CHS-828 appeared to kill cancer cells by depleting NAD. CHS 828 is presently being tested in Phase I clinical trials in collaboration with the European Organization for Research and Treatment of Cancer. Synonyms: CHS 828; CHS828; CHS-828; GMX-1778; GMX1778; GMX 1778. CAS No. 200484-11-3. Molecular formula: C19H22ClN5O. Mole weight: 371.869. BOC Sciences 6
CI-898 hydrochloride CI-898 is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). The presence of the cofactor NADPH enhances bind of CI-898 and DHFR. CI-898 inhibits growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also inhibits the growth of S. faecalis and S. aureus when used at concentrations less than 0.25 μg/ml. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine in mice with advanced stage P338 leukemia. Synonyms: Trimetrexate; CI 898 trihydrochloride; Trimetrexate trihydrochloride; TMTX. Grade: ≥98%. CAS No. 1658520-97-8. Molecular formula: C19H23N5O3·3HCl. Mole weight: 478.80. BOC Sciences 6
DAMPA DAMPA is a Methotrexate analog. Group: Biochemicals. Alternative Names: 4- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoic Acid; 2,4-Diamino-N10-methylpteroic Acid; 4-Amino-4-deoxy-10-methylpteroic Acid; 4-Amino-4-deoxy-N10-methylpteroic Acid; 4-Amino-4-deoxy-N10-methylpteroic Acid; 4-Deoxy-4-amino-N10-methylpteroic Acid; 4-[N-[(2,4-Diaminopyrimido[4,5-b]pyrazin-6-yl)methyl]-N-methylamino]benzoic Acid; NSC 133723. Grades: Highly Purified. CAS No. 19741-14-1. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 2
Worldwide
DAMPA Ethyl Ester A Methotrexate analog with altered ester group. Group: Biochemicals. Alternative Names: 4- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoic Acid Ethyl Ester; Ethyl p- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoate; NSC 694477. Grades: Highly Purified. CAS No. 43111-51-9. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
DAMPA Ethyl Ester DAMPA Ethyl Ester is an analog of Methotrexate, which is a folic acid antagonist used as an antineoplastic and antirheumatic. Uses: A methotrexate analog with altered ester group. Synonyms: 4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoic Acid Ethyl Ester; Ethyl p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoate; NSC 694477. Grade: ≥95%. CAS No. 43111-51-9. Molecular formula: C17H19N7O2. Mole weight: 353.38. BOC Sciences 7
DAMPA Methyl Ester A Methotrexate analog with altered ester group. Group: Biochemicals. Alternative Names: 4- [ [ (2, 4-Diamino-6-pteridinyl) methyl] methylamino] benzoic Acid Methyl Ester; Methyl 4-Amino-4-deoxy-10-methyl Pteroate; NSC 133722. Grades: Highly Purified. CAS No. 23853-09-0. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
Diethyl N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate Diethyl N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID94528, EINECS 256-127-9, Diethyl N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamate, 43170-88-3. Product Category: Heterocyclic Organic Compound. CAS No. 43170-88-3. Molecular formula: C24H30N8O5. Mole weight: 510.546 g/mol. Purity: 0.96. IUPACName: diethyl (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate. Canonical SMILES: CCOC(=O)CCC(C(=O)OCC)NC(=O)C1=CC=C(C=C1)N(C)CC2=CN=C3C(=N2)C(=NC(=N3)N)N. ECNumber: 256-127-9. Product ID: ACM43170883. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Diethyl methotrexate. Alfa Chemistry. 5

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