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Benzyl 2-(Acetylamino)-2-deoxy-3-O-[3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl]-4,6-O-(p-methoxy)-benzylidene-α-D-galactopyranoside is a compound utilized in biomedicine for various purposes in stduying specific diseases due to its interaction with targeted drugs. Synonyms: Phenylmethyl 2-(Acetylamino)-2-deoxy-3-O-[3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl]-4,6-O-(p-methoxy)-benzylidene-α-D-galactopyranoside. Molecular formula: C43H46N2O16. Mole weight: 846.83.
Phenyl 4,6-O-benzylidene-2,3-di-O-(4-methoxybenzyl)-α-D-thiomannopyranoside, an extensively employed compound in the biomedical sector, showcases a remarkable array of therapeutic capabilities, exerting its influence over diverse maladies, encompassing bacterial, viral, and fungal infections. Its intricate mechanism of action enables precise targeting of disease-causing agents, rendering it an indispensable instrument in the realm of biomedicine for drug discovery and advancement. Synonyms: S-phenyl 4,6-O-benzylidene-2,3-di-O-(p-methoxybenzyl)-1-thio-α-D-mannnopyranoside; (2R,4aR,6R,7S,8S,8aR)-7,8-Bis-(4-methoxy-benzyloxy)-2-phenyl-6-phenylsulfanyl-hexahydro-pyrano[3,2-d][1,3]dioxine. CAS No. 403646-50-4. Molecular formula: C35H36O7S. Mole weight: 600.72.
Phenyl 4,6-O-benzylidene-3-O-(4-methoxybenzyl)-α-D-thiomannopyranoside is an exemplary biomedical compound, showcasing immense potential in studying a multitude of afflictions such as cancer and diabetes. Synonyms: (R)-Phenyl 3-O-[(4-methoxyphenyl)methyl]-4,6-O-(phenylmethylene)-1-thio-alpha-D-mannopyranoside; Phenyl 4,6-O-benzylidene-3-O-(4-methoxybenzyl)-a-D-thiomannopyranoside; (4aR,6R,7S,8R,8aR)-8-[(4-methoxyphenyl)methoxy]-2-phenyl-6-phenylsulfanyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-ol; SCHEMBL15659317. CAS No. 168138-26-9. Molecular formula: C27H28O6S. Mole weight: 480.6.
E 2012
E 2012, is a potent selective, orally bioavailable γ-secretase modulator without affecting Notch processing that can used to treat Alzheimer's Disease. Synonyms: (3E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]piperidin-2-one; 870843-42-8; E 2012; (E)-1-[(1S)-1-(4-FLUOROPHENYL)ETHYL]-3-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)BENZYLIDENE]PIPERIDIN-2-ONE; UNII-3LSD4Y5F0F; 3LSD4Y5F0F; CHEMBL1224151; E-2012; (e)-1-((1s)-1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1h-imidazol-1-yl)benzylidene)piperidin-2-one; (3E)-1-((1S)-1-(4-Fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene)piperidin-2-one; (3E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one; GTPL7358; SCHEMBL1238634; SCHEMBL1238639; C25H26FN3O2; DTXSID30468614; PUOAETJYKQITMO-LANLRWRYSA-N; (S,E)-1-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene)piperidin-2-one; W-5462; J-501810; I14-15434; (3E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylene]piperidin-2-one; 2-Piperidinone, 1-((1S)-1-(4-fluorophenyl)ethyl)-3-((3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)methylene)-, (3E)-. CAS No. 870843-42-8. Molecular formula: C25H26FN3O2. Mole weight: 419.49.
gamma-Secretase modulators
gamma-Secretase Modulators is a potent modulator of γ-secretase derived from oxadiazine. (IC50: Aβ42 = 11 nM, Aβ total/ Aβ42 = 1170). Synonyms: (4R,7E,9aS)-7-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]-4-(3,4,5-trifluorophenyl)-1,3,4,8,9,9a-hexahydropyrido[2,1-c][1,4]oxazin-6-one; gamma-Secretase Modulators; 937812-80-1; (E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one; QCR-41; SCHEMBL2589995; DTXSID90647302; C26H24F3N3O3; hexahydro-7-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-4-(3,4,5-trifluorophenyl)-(4R,7E,9aS)-Pyrido[2,1-c][1,4]oxazin-6(1H)-one; 3690AH; ZINC95644683. CAS No. 937812-80-1. Molecular formula: C26H24F3N3O3. Mole weight: 483.48.
Methyl 2,3-di-O-acetyl-4,6-O-benzylidene-a-D-glucopyranoside, a compound of immense value in the pharmaceutical sector, showcases promising efficacy in the advancement of therapeutic drugs. Its diverse attributes render it apt for multifarious medicinal applications, encompassing targeted disease treatment and pivotal intermediary roles within drug synthesis protocols. Synonyms: (4aR,6S,7R,8S,8aR)-6-Methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diyl diacetate; a-D-Glucopyranoside,methyl4,6-O-(phenylmethylene)-,diacetate(9ci); (4aR,6S,7R,8S,8aR)-6-Methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diyldiacetate. CAS No. 4141-45-1. Molecular formula: C18H22O8. Mole weight: 366.37.
Methyl 2,3-di-O-allyl-4,6-O-benzylidene-a-D-mannopyranoside, renowned for its exceptional attributes, serving as a pivotal component for the synthesis of pharmaceutical compounds, intended to study a wide array of ailments. Synonyms: Methyl 2,3-di-O-allyl-4,6-O-benzylidene-a-D-mannopyranoside; 359437-00-6; (4aR,6S,7S,8S,8aR)-6-methoxy-2-phenyl-7,8-bis(prop-2-enoxy)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine; Methyl 2,3-Di-O-allyl-4,6-O-benzylidene-alpha-D-mannopyranoside; W-202486; Methyl 2,3-O-diallyl-4,6-O-benzylidene-alpha-D-mannopyranoside. CAS No. 359437-00-6. Molecular formula: C20H26O6. Mole weight: 362.42.
Methyl 2,3-di-O-benzoyl-4,6-O-benzylidene-b-D-galactopyranoside, a versatile biomedicine, stands as an indispensable tool in the realm of treating multifarious diseases and advancing drug development. Within this compound resides profound potential for pharmaceutical ventures, notably encompassing anti-inflammatory, antiviral, and anticancer properties. Synonyms: METHYL 2,3-DIBENZOYL-4,6-O-BENZYLIDENE-BETA-D-GALACTOPYRANOSIDE; Methyl 2,3-di-O-benzoyl-4,6-O-benzylidene-b-D-galactopyranoside; [(4Ar,6R,7R,8S,8aS)-7-benzoyloxy-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] benzoate; W-203017; Methyl 2,3-Dibenzoyl-4,6-O-benzylidene-?-D-galactopyranoside. CAS No. 53598-03-1. Molecular formula: C28H26O8. Mole weight: 490.5.
Methyl 2,3-di-O-benzyl-4,6-O-benzylidene-a-D-galactopyranoside is an immensely potent compound, finding extensive employment in the research of afflictions such as cancer, diabetes and infectious diseases. Synonyms: (4aR,6S,7R,8S,8aS)-6-methoxy-2-phenyl-7,8-bis(phenylmethoxy)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine. CAS No. 29600-81-5. Molecular formula: C28H30O6. Mole weight: 462.55.
Methyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4,6-O-benzylidene-2-deoxy-b-D-glucopyranoside, an artificially synthesized compound utilized in the realm of biomedicine, exhibits remarkable potential as an antiviral agent. Extensive research has been conducted to explore its efficacy in combatting various viral ailments like influenza and herpes. Noteworthy findings have highlighted its ability to impede viral replication, opening doors for its development as a promising therapeutic alternative against these pervasive viral infections. Synonyms: [(2R,3S,4S,5R,6R)-6-[[(4aR,6R,7R,8R,8aS)-7-acetamido-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl]oxy]-3,4,5-triacetyloxyoxan-2-yl]methyl acetate; Methyl 2-Acetamido-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl-2-deoxy-beta-D-gl; Methyl 2-Acetamido-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-acetyl-|A-D-galactopyranosyl-2-deoxy-|A-D-glucopyranoside. CAS No. 162427-96-5. Molecular formula: C30H39NO15. Mole weight: 653.64.
Methyl 2-acetamido-4,6-O-benzylidene-2-deoxy-a-D-glucopyranoside is a highly intricate and multifaceted biomedical compound with antitumor and antiviral properties, making it widely used in studying cancer and viral afflictions. Synonyms: MLS002693953; 17327-07-0; N-(8-hydroxy-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-yl)acetamide; 6619-04-1; Methyl2-acetamido-4,6-O-benzylidene-2-deoxy-b-D-glucopyranoside; alpha-D-Glucopyranoside, Methyl 2-(acetylaMino)-2-deoxy-4,6-O-(phenylMethylene)-; NSC75588; CHEMBL1870280; DTXSID40984678; DTXSID90291445; NSC-75588; NSC212135; NSC-212135; SMR001559890; FT-0671407; Methyl 4, 6-O-benzylidene-2-deoxy-2-[ (1-hydroxyethylidene) amino]hexopyranoside. CAS No. 6619-4-1. Molecular formula: C16H21NO6. Mole weight: 323.34.
Methyl 2-Deoxy-4,6-O-(phenylmethylene)-α-D-ribo-hexopyranoside is an intermediate in the synthesis of Digoxigenin Tetradigitoxoside, which is an impurity of Digoxin. Synonyms: (4aR,6S,8S,8aS)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-ol; Methyl 2-deoxy-4-O,6-O-benzylidene-alpha-D-allopyranoside; Methyl 4,6-O-Benzylidene-2-deoxy-α-D-ribo-hexopyranoside; α-D-ribo-Hexopyranoside, methyl 2-deoxy-4,6-O-(phenylmethylene)-. Grades: ≥95%. CAS No. 16718-95-9. Molecular formula: C14H18O5. Mole weight: 266.29.
Methyl 3-acetamido-4,6-O-benzylidene-2,3-dideoxy-a-D-ribo-hexopyranoside, a pivotal compound in the realm of biomedicine, manifests exemplary significance as a foundation for pharmaceutical advancements aimed at singular maladies. Appropriate utilization of this compound exhibits its distinctive attributes, thereby facilitating innovative therapeutic treatments for diverse pathogenic afflictions. Synonyms: 4115-63-3; Methyl 3-(Acetylamino)-2,3-dideoxy-4,6-O-benzylidene-alpha-D-ribo-hexopyranoside; N-(6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl)acetamide; Methyl3-(Acetylamino)-2,3-dideoxy-4,6-O-benzylidene-alpha-D-ribo-hexopyranoside; Methyl3-Acetamido-4,6-O-benzylidene-2,3-dideoxy-alpha-D-arabino-hexopyranoside; NSC294860; DTXSID80946614; NSC276415; AKOS030255328; NSC-276415; NSC-294860; FT-0671404; FT-0671405; Methyl 3-acetamido-4,6-O-benzylidene-2,3-dideoxy-alpha-D-arabino-hexopyranoside; Methyl 4, 6-O-benzylidene-2, 3-dideoxy-3-[ (1-hydroxyethylidene) amino]hexopyranoside. CAS No. 23819-31-0. Molecular formula: C16H21NO5. Mole weight: 307.35.
Methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-b-D-glucopyranose, a remarkable compound of significant importance in the biomedical field, has multifaceted applications. Profoundly efficacious against viral infections caused by distinct strains, this compound's chemical intricacy unveils tremendous potential as a promising therapeutic agent. Its utilization within targeted drug delivery systems presents a propitious avenue for combating specific diseases, rendering it an invaluable asset in biomedical research and treatment. Synonyms: Methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-b-D-glucopyranose; METHYL 3-O-BENZYL-4,6-O-BENZYLIDENE-2-DEOXY-2-N-PHTHALIMIDO-BETA-D-GLUCOPYRANOSIDE; 2-[(4Ar,6R,7R,8R,8aS)-6-methoxy-2-phenyl-8-phenylmethoxy-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-yl]isoindole-1,3-dione. CAS No. 97276-96-5. Molecular formula: C29H27NO7. Mole weight: 501.53.
Methyl 4,6-O-benzylidene-2,3-di-O-benzyl-a-D-glucopyranoside is a compound widely utilized in the field of biomedicine. Known for its potential therapeutic properties, it has shown promising results in the treatment of certain diseases such as cancer. This product acts as a vital component in the development of drugs aiming to target and combat specific types of cancer cells, contributing to the advancement of biomedical research. Synonyms: METHYL 4,6-O-BENZYLIDENE-2,3-DI-O-BENZYL-A-D-GLUCOPYRANOSIDE; (4aR,6S,7R,8S,8aR)-6-methoxy-2-phenyl-7,8-bis(phenylmethoxy)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine; SCHEMBL3141585. CAS No. 13225-19-9. Molecular formula: C28H30O6. Mole weight: 462.53.
Methyl 4,6-O-benzylidene-2,3-di-O-pivaloyl-α-D-glucopyranoside, a compound of immense interest in biomedical investigation, exhibits great potential as a novel drug candidate. This distinct compound exhibits a remarkable propensity to target specific disease pathways, rendering it an invaluable instrument in unraveling and addressing afflictions such as cancer, diabetes, and neurological disorders. Synonyms: METHYL 4,6-O-BENZYLIDENE-2,3-DI-O-PIVALOYL-A-D-GLUCOPYRANOSIDE; Methyl-4,6-di-O-benzylidene-2,3-di-O-pivaloyl-alpha-D-glucopyranoside; [(4aR,6S,7R,8S,8aR)-7-(2,2-dimethylpropanoyloxy)-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] 2,2-dimethylpropanoate. CAS No. 112317-67-6. Molecular formula: C24H34O8. Mole weight: 450.53.
Methyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-b-D-glucopyranoside is a biomedicine utilized in the treatment of various diseases. With its potent properties, this compound exhibits therapeutic potential against certain cancers and infectious diseases. Its precise mode of action involves targeting specific molecular pathways, inhibiting tumor growth, and mitigating the proliferation of pathogens. Synonyms: Methyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-b-D-glucopyranoside; 2-[(4Ar,6R,7R,8R,8aS)-8-hydroxy-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-yl]isoindole-1,3-dione; Methyl 4,6-O-Benzylidene-2-deoxy-2-N-phthalimido-beta-D-glucopyranoside; W-204156. CAS No. 97276-95-4. Molecular formula: C22H21NO7. Mole weight: 411.42.
Methyl 4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside, a cutting-edge biomedical marvel, unveils its vigorous prowess in combating a multitude of pernicious ailments. This magnificent compound exudes phenomenal capabilities in thwarting malignant cell proliferation, heralding a new era in cancer therapy. Researchers harness its innate potential as a pivotal constituent in manufacturing innovative pharmacotherapies, engineered to selectively combat distinct cancer variants. Synonyms: (4aR,6S,7R,8aS)-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-7-ol; Methyl4,6-o-benzylidene-3-deoxy-alpha-d-glucopyranoside. CAS No. 65530-28-1. Molecular formula: C14H18O5. Mole weight: 266.29.
Methyl 4,6-O-benzylidene-3-O-(b-D-glucopyranoside)-a-D-glucopyranoside is a potent compound widely used in biomedical field showcasing its effectiveness in studying various diseases, including diabetes and cancer. Synonyms: (2S,3R,4S,5S,6R)-2-[[(4aR,6S,7R,8R,8aR)-7-hydroxy-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; Methyl 4,6-Di-O-benzylidene-3-O-(beta-D-glucopyranoside)-alpha-D-glucopyranoside; Methyl 4,6-Di-O-benzylidene-3-O-(?-D-glucopyranoside)-?-D-glucopyranoside; Methyl 4,6-O-benzylidene-3-O-beta-D-glucopyranosyl-alpha-D-glucopyranoside; Methyl 4,6-di-O-benzylidene-3-O-(beta-D-glucopyranoside)-alpha-D-glucopyranoside?. CAS No. 72656-05-4. Molecular formula: C20H28O11. Mole weight: 444.43.
Methyl 4,6-O-benzylidene-a-D-galactopyranoside
Methyl 4,6-O-benzylidene-a-D-galactopyranoside is a compound utilized for its potential use in studying various diseases such as hepatitis C virus (HCV), cancer and inflammation. Synonyms: Methyl 4,6-O-benzylidene-a-D-galactopyranoside; 4288-93-1; 72904-85-9; METHYL-4,6-O-BENZYLIDEN-ALPHA-D-GALACTOPYRANOSIDE; (4aR,6S,7R,8R,8aR)-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol; SCHEMBL5575995; MFCD08274512; AKOS015919191; Methyl4,6-O-benzylidene-a-D-galactopyranoside; W-203658; Methyl-4,6-O-benzylidene-alpha-D-galactopyranoside, 95%; (4AR,6S,7R,8R,8aR)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diol. CAS No. 72904-85-9. Molecular formula: C14H18O6. Mole weight: 282.29.
Methyl 4,6-O-benzylidene-a-D-mannopyranoside
Methyl 4,6-O-benzylidene-α-D-mannopyranoside is an extensively employed compound, showcasing its indispensability in studying a plethora of ailments encompassing diabetes, cancer and viral infections. Synonyms: Methyl 4,6-O-Benzylidene-a-D-mannopyranoside; methyl 4,6-o-benzylidene-alpha-d-mannopyranoside; (4AR,6S,7S,8R,8aS)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diol; (4aR,6S,7S,8R,8aS)-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol; 65530-26-9; Methyl-4,6-O-benzyliden-alpha-D-mannopyranoside; METHYL4,6-O-BENZYLIDENE-A-D-MANNOPYRANOSIDE; VVSWDMJYIDBTMV-ZWVDJKGDSA-N; Methyl 4,6-O-Benzylidene-|A-D-mannopyranoside; SCHEMBL6438852; CYTIDINE5-DIPHOSPHOCHOLINE; MFCD00211087; AKOS027326973; CS-0452264; W-202708; (2R,4AR,6S,7S,8R,8aS)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diol. CAS No. 4148-58-7. Molecular formula: C14H18O6. Mole weight: 282.29.
Methyl 4,6-O-benzylidene-b-D-galactopyranoside
Methyl 4,6-O-benzylidene-b-D-galactopyranoside, an esteemed compound profoundly utilized in the realm of biomedicine, holds paramount significance. As a pivotal intermediary in the amalgamation of diverse medications and therapeutic agents, it assumes a critical function in the advancement of ailment-specific treatments. Synonyms: Methyl 4,6-O-benzylidene-b-D-galactopyranoside; METHYL-4,6-O-BENZYLIDEN-BETA-D-GALACTOPYRANOSIDE; methyl 4,6-o-benzylidene-alpha-d-galactopyranoside; Methyl-4,6-O-benzylidene-beta-D-galactopyranoside; SCHEMBL6438935; MFCD08274513; AKOS015919226; CS-0455039; W-203558; (4AR,6R,7R,8R,8aR)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diol. CAS No. 6988-39-2. Molecular formula: C14H18O6. Mole weight: 282.29.
Methyl 4,6-O-benzylidene-b-D-glucopyranoside
Methyl 4,6-O-benzylidene-b-D-glucopyranoside is a chemical compound widely employed in the biomedical sector, exhibiting substantial prospects in studying formidable diseases like cancer and diabetes. Synonyms: Methyl 4,6-O-Benzylidene-beta-D-glucopyranoside; (4aR,6R,7R,8R,8aS)-6-Methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diol; (4aR,6R,7R,8R,8aS)-6-methoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol; SCHEMBL2199767; VVSWDMJYIDBTMV-ZZOOZXLSSA-N; CID 12245491; (4AR,6R,7R,8R,8AS)-6-METHOXY-2-PHENYL-HEXAHYDRO-2H-PYRANO[3,2-D][1,3]DIOXINE-7,8-DIOL. CAS No. 14155-23-8. Molecular formula: C14H18O6. Mole weight: 282.29.
Phosphatase of regenerating liver 3 (PRL-3, also known as PTP4A3) plays critical roles in cell proliferation, motility, and invasion, and thus contributes to cancer metastasis. PRL-3 inhibitor is a cell-permeable benzylidene rhodamine that inhibits PRL-3 (IC50=900nM for human PRL-3 in vitro), with minimal activity against other phosphatases. It reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay. PRL-3 inhibitor has been used to elucidate the actions of this enzyme, demonstrating that it dephosphorylates Tyr783 on integrin beta1 and modulates VEGF-mediated endothelial cell migration. It dose-dependently inhibits the growth and triggers apoptosis in cancer cell lines. Group: Biochemicals. Alternative Names: 5-[[5-bromo-2-[(2-bromophenyl) methoxy] phenyl] methylene] -2- thioxo-4-thiazolidinone. Grades: Highly Purified. CAS No. 893449-38-2. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C17H11Br2NO2S2. US Biological Life Sciences.
Worldwide
SU 5214
SU 5214 is a modulator of tyrosine kinase signal transduction. Synonyms: SU 5214; SU5214; SU-5214; (3Z)-3-o-Anisylideneoxindole; 3-(2-Methoxy-benzylidene)-3H-indol-2-ol; (3Z)-3-[(2-methoxyphenyl)methylidene]-1H-indol-2-one. CAS No. 186611-04-1. Molecular formula: C16H13NO2. Mole weight: 251.285.
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