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It is a dimethyl analogue of Guanosine, a purine nucleoside and a novel influenza neuraminidase inhibitor. Synonyms: N1,2'-O-dimethylguanosine; Guanosine, 1-methyl-2'-O-methyl-; 1-Methyl-2'-O-methylguanosine; 2'-O-Methyl-1-methylguanosine. Grades: ≥95%. CAS No. 73667-71-7. Molecular formula: C12H17N5O5. Mole weight: 311.29.
1-Methyl-6-thioguanosine
1-Methyl-6-thioguanosine is a compound useful in organic synthesis. Synonyms: 1-Methyl-6-thio-guanosine. CAS No. 55727-08-7. Molecular formula: C11H15N5O4S. Mole weight: 313.33.
1-Methylguanosine
1-Methylguanosine is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patients with malignant tumours. These nucleosides have been proposed as tumour markers. Their measurement could provide a non-invasive diagnostic method, help identify different cancers, and monitor any therapeutic effects. Synonyms: N1-Methylguanosine; Guanosine, 1-methyl-; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methyl-1H-purin-6(9H)-one; 1-Methyl-2-amino-9-(β-D-ribofuranosyl)-9H-purine-6(1H)-one. Grades: ≥95%. CAS No. 2140-65-0. Molecular formula: C11H15N5O5. Mole weight: 297.27.
2',3',5'-Tri-O-acetyl-6-S-methyl-6-thio-guanosine
2',3',5'-Tri-O-acetyl-6-S-methyl-6-thio-guanosine, a nucleoside analog, has been extensively studied for its efficacy in disrupting viral RNA synthesis and inhibiting the replication of Hepatitis C Virus (HCV). Furthermore, promising research suggests its potential utility as a treatment option for certain malignant neoplasms, such as leukemia and lymphoma. Grades: ≥95%. CAS No. 80681-58-9. Molecular formula: C17H21N5O7S. Mole weight: 439.44.
23S rRNA (guanosine2251-2'-O)-methyltransferase
The enzyme catalyses the methylation of guanosine2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. Group: Enzymes. Synonyms: rlmB (gene name); yifH (gene name). Enzyme Commission Number: EC 2.1.1.185. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1784; 23S rRNA (guanosine2251-2'-O)-methyltransferase; EC 2.1.1.185; rlmB (gene name); yifH (gene name). Cat No: EXWM-1784.
2',5'-CYCLIC METHYLPHOSPHONATE GUANOSINE
Heterocyclic Organic Compound. CAS No. 129546-31-2. Catalog: ACM129546312.
Spb1p is a site-specific 2'-O-ribose RNA methyltransferase that catalyses the formation of 2'-O-methylguanosine2922, a universally conserved position of the catalytic center of the ribosome that is essential for translation. 2'-O-Methylguanosine2922 is formed at a later stage of the processing, during the maturation of of the 27S pre-rRNA. In absence of snR52, Spb1p can also catalyse the formation of uridine2921. Group: Enzymes. Synonyms: Spb1p (gene name); YCL054W (gene name). Enzyme Commission Number: EC 2.1.1.167. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1764; 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase; EC 2.1.1.167; Spb1p (gene name); YCL054W (gene name). Cat No: EXWM-1764.
2-Amino-6-methoxy-2'-C-methylguanosine 5'-triphosphate triethylammonium salt
2-Amino-6-methoxy-2'-C-methylguanosine 5'-triphosphate triethylammonium salt, a remarkable chemical, unveils its unfathomable effects by unraveling the intricate mechanisms underlying RNA methylation, RNA splicing, and RNA modification. With a structural resemblance to guanosine triphosphate (GTP), this analog emerges as a pivotal tool fostering innovative research endeavors concerning the enigmatic domains of cancer biology and genetic disorders. Molecular formula: C12H20N5O14P3·C24H60N4. Mole weight: 955.99.
2'-C-beta-Methylguanosine
2'-C-β-MethylGuanosine is an anti-HCV agent. 2'-C-β-MethylGuanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus. Uses: A nucleoside derivative as antiviral, antitumor, and antidiabetic prodrug agents. Synonyms: 2'-C-Methylguanosine; 2'-C-β-MethylGuanosine; 2-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-(2-C-methyl-beta-D-ribofuranosyl)-. Grades: ≥95%. CAS No. 374750-30-8. Molecular formula: C11H15N5O5. Mole weight: 297.27.
2-C- β-MethylGuanosine 5-Triphosphate is a derivative of 2-C- β-MethylGuanosine (M311820) which is an anti-HCV agent. 2-C- β-MethylGuanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C11H18N5O12P3 xC6H15N, Molecular Weight: 505.21. US Biological Life Sciences.
Worldwide
2-C-methyl-6-O-methyl-guanosine
2-C-methyl-6-O-methyl-guanosine - an exalted nucleoside analog flourishing in the realm of biomedical applications. As a prodigious antiviral agent, its dominion extends to combating the perils inflicted by RNA viruses like hepatitis C and respiratory syncytial virus (RSV). Proficiently curbing viral replication and subduing the viral life cycle, it has garnered reverence among scientific circles. Moreover, its boundless panorama of therapeutic possibilities in countering diverse viral afflictions continues to enthrall researchers worldwide. Beware, for this extraordinary entity is unrivaled in its prowess. Synonyms: (2R,3R,4R,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol. CAS No. 714249-80-6. Molecular formula: C12H17N5O5. Mole weight: 311.29.
2'-Deoxy-3', 5'-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-8-[ (1-methyl-6-phenyl-1H-imidazo[4, 5-b]pyridin-2-yl) amino]-6-O- (phenylmethyl) guanosine is an intermediate in the synthesis of 2-Deoxyguanosine-C8 adducts with mutagenic/carcinogenic heterocyclic amines. Group: Biochemicals. Grades: Highly Purified. CAS No. 896719-58-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C42H57N9O4Si2. US Biological Life Sciences.
2'-Deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-8-[(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]-6-O-(phenylmethyl)guanosine is an intermediate in the synthesis of 2'-Deoxyguanosine-C8 adducts with mutagenic/carcinogenic heterocyclic amines. CAS No. 896719-58-7. Molecular formula: C42H57N9O4Si2. Mole weight: 808.13.
2'-Deoxy-3', 5'-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-8-[ (1-methyl-6-phenyl-1H-imidazo[4, 5-b]pyridin-2-yl) amino]-guanosine is an intermediate in the synthesis of 2-Deoxyguanosine-C8 adducts with mutagenic/carcinogenic heterocyclic amines. Group: Biochemicals. Grades: Highly Purified. CAS No. 915092-62-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C35H51N9O4Si2. US Biological Life Sciences.
2'-Deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-8-[(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]-guanosine is an intermediate in the synthesis of 2'-Deoxyguanosine-C8 adducts with mutagenic/carcinogenic heterocyclic amines. Synonyms: 2'-Deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-8-[(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]-guanosine; 915092-62-5. CAS No. 915092-62-5. Molecular formula: C35H51N9O4Si2. Mole weight: 718.01.
2'-Deoxy-5'-O-DMT-N2-isobutyryl-O6-methylguanosine 3'-CE phosphoramidite is an immensely popular building block in the biomedical sector as it is instrumental in synthesizing modified RNA with methylated guanosines. Its high purity and steadfastness make it the best bet for manufacturing modified RNA molecules. The potential of this product extends far beyond that of just an ideal building block-- it can greatly aid in the development of therapeutic drugs which can be used to combat an assortment of viral diseases and cancers. Synonyms: 2'-Deoxy-5'-O-DMT-N2-isobutyryl-O6-methyl-D-guanosine 3'-CE phosphoramidite; 5'-O-DMT-N2-isobutyryl-O6-methyl-2'-deoxyguanosine 3'-CE phosphoramidite. Grades: 98%. Molecular formula: C45H56N7O8P. Mole weight: 853.96.
2'-Deoxy-5'-O-DMT-N2-methylguanosine 3'-CE phosphoramidite is a crucial component in the biomedical field, finding its application in synthesizing nucleic acids. Its primary utility lies in the synthesis of altered RNA, particularly in the introduction of methylguanosine modifications. This exceptional product empowers researchers to delve into the intricate interplay between methylguanosine modifications and the structure and function of RNA. Synonyms: N2-Methyl-dG CEP; 2'-Deoxy-5'-O-DMT-N2-methyl-D-guanosine 3'-CE phosphoramidite; 5'-O-DMT-N2-methyl-2'-deoxyguanosine 3'-CE phosphoramidite. Grades: 95%. CAS No. 808132-80-1. Molecular formula: C41H50N7O7P. Mole weight: 783.85.
2'-Deoxy-6-O-methyl-guanosine
It is a DNA adduct. Synonyms: O6-Methyldeoxyguanosine; O6-Methyl-2'-deoxyguanosine; 2'-Deoxy-O(6)-methylguanosine; 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-6-methoxy-9H-purin-2-amine; O6-Methyl-dG; 2-amino-6-methoxy-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine; (2R,3S,5R)-5-(2-amino-6-methoxy-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2-Amino-9-(2-deoxy-β-D-ribofuranosyl)-6-methoxy-9H-purine. Grades: ≥95%. CAS No. 964-21-6. Molecular formula: C11H15N5O4. Mole weight: 281.27.
2'-Deoxy-8-methylthio-guanosine
2'-Deoxy-8-methylthio-guanosine, known for its remarkable antiviral attributes, holds great significance in the biomedical realm. Its utilization prevails as a potent therapeutic solution against various viral ailments such as hepatitis C and herpes simplex. This compound adeptly hampers viral replication by precisely targeting pivotal enzymes involved in the intricate viral life cycle. Evidently, the profound mechanism of action it possesses renders this compound an indispensable asset for rigorous viral infection investigations and therapeutic interventions. Synonyms: 8-methylthio-2'-deoxyguanosine; Guanosine, 2'-deoxy-8-(methylthio)-. Grades: ≥95%. CAS No. 157946-92-4. Molecular formula: C11H15N5O4S. Mole weight: 313.33.
2'-Deoxy-N-(2-methyl-1-oxopropyl)-guanosine
2'-Deoxy-N-(2-methyl-1-oxopropyl)-guanosine is used to prepare methylene carboxamide-linked dinucleotides as HIV-1 nucleocapsid protein NCp7 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 68892-42-2. Pack Sizes: 250mg, 1g. Molecular Formula: C14H19N5O5, Molecular Weight: 337.33. US Biological Life Sciences.
Worldwide
2'-Methyl-guanosine-(iBu)-succinyl-CPG
2'-Methyl-guanosine-(iBu)-succinyl-CPG is a crucial biomedicine product used for solid-phase synthesis of oligonucleotides. It serves as a key building block for the chemical synthesis of modified nucleic acids. With its unique succinyl modification, this CPG derivative enables efficient incorporation into oligonucleotides for pharmaceutical research and diagnostic applications related to drug screening, target identification, and disease detection.
2'- (N-Methylanthraniloyl) guanosine 3',5'-Cyclicmonophosphate, Sodium Salt (MANT-cGMP)
A blue fluorescent derivative of cGMP is a useful substrate the assay of cyclic nucleotide phosphdiesterase. Also inhibits calmodulin-dependent activation of cyclic nucleotide phosphodiesterase by peptide segments of HIV envelope glycoproteins has been monitored using MANT-cGMP.Fluorescence: max. Abs. 359nm; max. Em. 448nm; e x 10-3: 5.2. Group: Biochemicals. Alternative Names: Cyclic 3,5-(hydrogen phosphate) 2-[2-(methylamino)benzoate] Guanosine Monosodium Salt; MANT-cGMP. Grades: Highly Purified. CAS No. 221905-46-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
2'-(O-Methyl)-guanosine
2'-(O-Methyl)-guanosine is a modified guanosine used mostly in molecular biology studies. It is involved in the biological regulation of RNA structures and protein synthesis. It has potential therapeutic applications in research of viral disease and neurodegenerative disorders. Grades: ≥ 98% by HPLC. Molecular formula: C11H15N5O5. Mole weight: 297.27.
2'-O-Methylguanosine
It is a guanine nucleoside analogue that is used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA virus polymerases. Synonyms: Guanosine, 2'-O-methyl-; 2'-O-MethylGuanosine; O2'-Methylguanosine; 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-amino-9-(2-O-methyl-beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 2140-71-8. Molecular formula: C11H15N5O5. Mole weight: 297.27.
2'-O-Methylguanosine 5'-triphosphate
2'-O-Methylguanosine 5'-triphosphate is a vital biomolecule extensively utilized in diverse biomedical applications, serving as an essential substrate for RNA research and development and modification. Notably, this compound finding extensive application in research endeavors aimed at unraveling the intricate mechanisms underlying RNA metabolism, RNA splicing, and RNA editing. Synonyms: 2'-O-Methyl-GTP; 2'-O-methylguanosine 5'-(tetrahydrogen triphosphate); [[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate; 6H-Purin-6-one, 2-amino-1, 9-dihydro-9-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-2-O-methyl-b-D-ribofuranosyl]-; Guanosine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-. Grades: ≥97% by HPLC. CAS No. 61556-44-3. Molecular formula: C11H18N5O14P3. Mole weight: 537.21.
2'-O-Methylguanosine-5'-triphosphate trilithium salt
2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities. Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[ ({[ (hydroxyphosphinato) oxy]phosphinato}oxy) phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grades: ≥97% by HPLC. Molecular formula: C11H15Li3N5O14P3. Mole weight: 555.00.
2'-O-Methylguanosine-5'-triphosphate trisodium salt
2'-O-Methylguanosine-5'-triphosphate trisodium salt is a nucleotide analog with diverse applications. Its use in RNA synthesis not only increases stability but also specificity for protein binding. When utilized as a probe, it is an invaluable tool for investigating RNA structure and function. Beyond such scientific applications, this compound also boasts potential therapeutic benefits when targeting viral diseases and cancer. Synonyms: 2'-O-Me-GTP trisodium salt; Trisodium 5'-O-[ ({[ (hydroxyphosphinato) oxy]phosphinato}oxy) phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), sodium salt (1:3); sodium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grades: ≥97% by HPLC. Molecular formula: C11H15N5Na3O14P3. Mole weight: 603.15.
2'-O-Methyl-N2-isobutyroylguanosine
2'-O-Methyl-N2-isobutyroylguanosine is a biomedicine used in the reserch of certain diseases, including cancer. It acting as an antineoplastic compound and exhibiting potent activity against specific tumor cells. Its mechanism of action involves inhibiting cell growth and inducing apoptosis. Synonyms: N2-Isobutyryl-2'-O-methylguanosine; N2-Isobutyryl-2'-O-methyl-D-guanosine; IBU-2'-OME-G; N2-isobutyryl-O2'-methyl-guanosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 2'-O-methyl-N-(2-methyl-1-oxopropyl)-. Grades: ≥95%. CAS No. 63264-29-9. Molecular formula: C15H21N5O6. Mole weight: 367.36.
2'-O-Methyl-N2-methylguanosine
2'-O-Methyl-N2-methylguanosine, an indispensable compound in biomedicine, assumes a pivotal role in drug development for diverse ailments. Its myriad applications encompass investigating cancer and viral infections, as well as pioneering antiviral and antineoplastic therapies. Synonyms: Guanosine, N-methyl-2'-O-methyl-; N,2'-O-Dimethylguanosine; N2,2'-O-dimethylguanosine; 9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-(methylamino)-1,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 135023-21-1. Molecular formula: C12H17N5O5. Mole weight: 311.29.
2'-O-Methyl-N2,N2-dimethyl-guanosine
It is a modified nucleoside in tRNA of hyperthermophilic archaebacteria. Synonyms: N2,N2,2'-O-Trimethylguanosine; Guanosine, N,N-dimethyl-2'-O-methyl-; N,N,2'-O-Trimethylguanosine; N,N-Dimethyl-2'-O-methylguanosine. Grades: ≥95%. CAS No. 113886-73-0. Molecular formula: C13H19N5O5. Mole weight: 325.32.
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-methylguanosine 3'-CE phosphoramidite is an invaluable compound in the field of compound, playing a pivotal role as a foundation for constructing modified nucleotides. By incorporating the N2-methylguanosine modification into oligonucleotides, this phosphoramidite enhances both stability and targeting functionalities, thereby facilitating the application of disease-specific reserchs. Synonyms: 2'-TBDMS-5'-Dimethoxytrityl-N2-methyl-guanosine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C47H64N7O8PSi. Mole weight: 914.11.
2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine, a vital reagent in the biomedical sector, holds immense significance for synthesizing diverse antiviral medications. Its unparalleled structure and mechanism of action contribute significantly to combating viral infections like hepatitis C and HIV. Synonyms: 2'-TBDMS-ibu-rG; 2'-O-(tert-Butyldimethylsilyl)-N-isobutyrylguanosine; Guanosine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine. Grades: 96%. CAS No. 182007-86-9. Molecular formula: C20H33N5O6Si. Mole weight: 467.59.
Used in the preparation of 2'-Deoxyguanosine-C8 adducts. Synonyms: 2'-Deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-8-[(3,8-dimethyl-3H-imidazo[4,5-f]quinoxalin-2-yl)amino]-6-O-(phenylmethyl)-guanosine. CAS No. 896719-54-3. Molecular formula: C40H56N10O4Si. Mole weight: 797.11.
Used in the preparation of 2'-Deoxyguanosine-C8 adducts. Group: Biochemicals. Alternative Names: 2'-Deoxy-3', 5'-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-8-[ (3, 8-dimethyl-3H-imidazo[4, 5-f]quinoxalin-2-yl) amino]-6-O- (phenylmethyl) -guanosine. Grades: Highly Purified. CAS No. 896719-54-3. Pack Sizes: 10mg. US Biological Life Sciences.
dG-C8-MeIQx derivative. MeIQx-DNA adducts exist in human tissues and this adduct formation may be involved in human cancer development. Synonyms: N2-(Deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. Molecular formula: C33H50N10O4Si2. Mole weight: 706.99.
dG-C8-MeIQx (D29615) derivative. MeIQx-DNA adducts exist in human tissues and this adduct formation may be involved in human cancer development. Group: Biochemicals. Alternative Names: N2-(Deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
dG-C8-MeIQx-d3 derivative. MeIQx-DNA adducts exist in human tissues and this adduct formation may be involved in human cancer development. Synonyms: N2-(Deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-d3. Molecular formula: C33H47D3N10O4Si2. Mole weight: 710.
dG-C8-MeIQx-d3 derivative. MeIQx-DNA adducts exist in human tissues and this adduct formation may be involved in human cancer development. Group: Biochemicals. Alternative Names: N2-(Deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Used in the preparation of nucleotide analogs. Group: Biochemicals. Alternative Names: 3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine; 6H-Furo[3,2-f]-1,3,5,2,4-trioxadisilocin, guanosine deriv.; 3', 5'-O-Tetraisopropyl disiloxane Guanosine. Grades: Highly Purified. CAS No. 88183-82-8. Pack Sizes: 5mg. US Biological Life Sciences.
3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine is a versatile biomedical compound, showcasing remarkable antiviral efficacy. It selectively combats specific viral strains with vigor. Its superior inhibitory prowess impedes replication of targeted viruses, rendering it an indispensable asset in the realms of pharmaceutical development and biomedical exploration. Synonyms: 3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine; 6H-Furo[3,2-f]-1,3,5,2,4-trioxadisilocin, guanosine deriv.; 3',5'-O-Tetraisopropyldisiloxane Guanosine. Molecular formula: C22H39N5O6Si2. Mole weight: 525.75.
3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is a vital compound used in biomedicine. It is commonly employed in drug formulation and research regarding diseases such as cancer, cellular signaling disorders, and viral infections. This product, known for its therapeutic potential, can provide valuable insights into the development of targeted therapies and the design of novel drugs. Synonyms: 3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine; 6H-Furo[3,2-f]-1,3,5,2,4-trioxadisilocin, guanosine deriv.; 3',5'-O-Tetraisopropyldisiloxane guanosine. CAS No. 88183-82-8. Molecular formula: C22H39N5O6Si2. Mole weight: 525.75.
Used in the preparation of nucleotide analogs. Group: Biochemicals. Alternative Names: 3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine-13C,15N2; 6H-Furo[3,2-f]-1,3,5,2,4-trioxadisilocin, guanosine deriv.-13C,15N2; 3', 5'-O-Tetraisopropyl disiloxane Guanosine-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Heterocyclic Organic Compound. Alternative Names: 3'-(methylanthraniloyl)-2'-deoxy-guanosine diphosphate. CAS No. 127383-33-9. Catalog: ACM127383339.
3'-(O-Methyl)-guanosine
3'-(O-Methyl)-guanosine is a crucial compound widely used in the biomedical industry known for its antiviral properties. It is utilized in the development of drugs for the reserch of viral infections like hepatitis C and influenza. Grades: ≥ 98% by HPLC. Molecular formula: C11H15N5O5. Mole weight: 297.27.
3'-O-Methylguanosine
3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. Synonyms: 3'-O-Methyl-D-guanosine; 3'-O-Methylguanosine; O3'-methyl-guanosine; 3'-OMe-G; 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 10300-27-3. Molecular formula: C11H15N5O5. Mole weight: 297.27.
4'-a-C-Methylguanosine
4'-a-C-Methylguanosine, an indispensible element in the realm of biomedical research, stands as a pivotal piece for the analysis of antiviral therapeutic measures. Its profound impact extends to inhibiting the replication of RNA viruses, encompassing the pernicious respiratory syncytial virus and the daunting flaviviruses. This compound, with its unmatched relevance, becomes a linchpin in the process of formulating prospective pharmaceutical solutions aimed at combating these afflictions. Synonyms: 4'-Methylguanosine; Guanosine, 4'-C-methyl-; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 4'-α-C-Methylguanosine; 2-Amino-9-[5-deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-3,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 153186-32-4. Molecular formula: C11H15N5O5. Mole weight: 297.27.
5'-DMT-2'-(O-methyl)-guanosine (N-iBu)
5'-DMT-2'-(O-methyl)-guanosine (N-iBu) is a prominent biomedical compound extensively employed in nucleotide chemistry research assuming a paramount significance in fabricating altered nucleotides and probing their plausible ramifications in related developments. Its application in studying antiviral therapies exhibiting substantial potential by deftly manipulating viral replication and protein research and development pathways. Grades: ≥ 98% by HPLC (Isomeric impurity 0 %). Molecular formula: C36H39N5O8. Mole weight: 669.72.
5'-DMT-2'-(O-methyl)-guanosine (N-PAC)
5'-DMT-2'-(O-methyl)-guanosine (N-PAC) is a remarkable pharmacological compound, extensively employed in the research of select malignant neoplasms and viral afflictions. Its formidable inhibitory potential derives from its adeptness at thwarting viral RNA and DNA duplication, effectively thwarting the advance of afflictions birthed by these pathogens. Grades: ≥ 98% by HPLC. Molecular formula: C40H39N5O9. Mole weight: 733.77.
5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine is a revolutionary biomedical substance renowned for its remarkable antiviral and antiproliferative attributes. Synonyms: N-(9-{(1R,3R,4R,7S)-1-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-7-hydroxy-2,5-dioxa-bicyclo[2.2.1]hept-3-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O,4'-C-methylene-N-(2-methyl-1-oxopropyl)-; (1R,3R,4R,7S)-1-(4,4'-Dimethoxytrityloxymethyl)-7-hydroxy-3-(2-N-isobutyrylguanin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane. Grades: ≥95%. CAS No. 206055-72-3. Molecular formula: C36H37N5O8. Mole weight: 667.71.
5'-O-(Dimethoxytrityl)-N2-methyl-2'-deoxy-guanosine is an indispensable compound, emerging as a pivotal compound for the research and development of deoxyribonucleic acid (DNA) moieties. Its intrinsic value resides in the research of pharmaceuticals, specifically in the sphere of antiviral therapeutics and remedies aimed at combatting afflictions pertaining to DNA. Synonyms: 2'-Deoxy-5'-O-[(2,3-dimethoxyphenyl)(diphenyl)methyl]-N-methylguanosine. CAS No. 869354-96-1. Molecular formula: C32H33N5O6. Mole weight: 583.64.
5'-O-DMT-2'-O-methylguanosine
5'-O-DMT-2'-O-methylguanosine, a nucleoside analogue, finds its purpose in biomedical research due to its potential antiviral activity against RNA viruses, an area of significant scientific interest. Its inhibitory role in the replication of notorious viruses such as Zika virus and hepatitis C virus warrants further academic study. Synonyms: 2'-O-Methyl-5'-O-DMT-D-guanosine; 5'-O-Dimethoxytrityl-2'-O-methylguanosine; 5'-O-DMT-2'-O-methyl-D-guanosine. Grades: ≥ 98% (HPLC). CAS No. 103285-24-1. Molecular formula: C32H33N5O7. Mole weight: 599.65.
5'-O-DMT-2'-O-methylguanosine
5'-O-DMT-2'-O-methylguanosine. Group: Biochemicals. Alternative Names: 2'-O-Methyl-5'-O-DMT-D-guanosine; 5'-O-Dimethoxytrityl-2'-O-methylguanosine. Grades: Highly Purified. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite is a highly specialized compound used in biomedical research for the synthesis of modified RNA strands. It functions as a phosphoramidite reagent for the site-specific incorporation of 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine during oligonucleotide synthesis. This modified RNA guanosine derivative is particularly valuable for investigating the role of specific RNA sequences and structures in various biological processes and diseases. Synonyms: 2'-OMe-iPr-Pac-G phosphoramidite; 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methyl-D-guanosine 3'-CE phosphoramidite. Grades: 97%. Molecular formula: C52H62N7O10P. Mole weight: 976.09.
5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine
5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine, a remarkable antiviral agent employed in advanced biomedical investigations, defies viral replication across diverse strains, such as the treacherous influenza and herpes simplex virus. Equally significant, this compound boasts unrivaled eminence in probing RNA biology and delineating protein synthesis intricacies. Scientific affluence beckons its application, impelling groundbreaking inquiries exploring viral replication mechanisms and pioneering antiviral therapies. Synonyms: N2-Isobutyryl-5'-O-DMT-2'-O-methyl-D-guanosine. Grades: ≥ 98% (HPLC). CAS No. 114745-26-5. Molecular formula: C36H39N5O8. Mole weight: 669.74.
5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine
5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine. Group: Biochemicals. Alternative Names: N2-Isobutyryl-5'-O-DMT-2'-O-methyl-D-guanosine. Grades: Highly Purified. CAS No. 114745-26-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C36H39N5O8. US Biological Life Sciences.
Worldwide
5'(R)-C-Methylguanosine
5'(R)-C-Methylguanosine, a vital research tool in the biomedical industry, is a highly intricate biomedicine product. This modified guanosine derivative holds immense significance in RNA metabolism. Its utilization primarily centers around the exploration of RNA modification's profound influence on gene expression. Moreover, this compound provides invaluable insights into the involvement of modified nucleosides in various afflictions like cancer and neurological disorders. Empowering scientific investigations, it serves as an indispensable asset for discerning the intricacies of disease pathogenesis and therapeutic interventions. Synonyms: NSC 347203; 9-(6'-Deoxy-beta-D-allofuranosyl)guanine; 2-Amino-9-(6-deoxy-β-D-allofuranosyl)-3,9-dihydro-6H-purin-6-one; 9-DAFG. Grades: ≥95%. CAS No. 85421-89-2. Molecular formula: C11H15N5O5. Mole weight: 297.27.
5'-tert-Butyldimethylsilyloxy-2'-deoxyguanosine
5'-tert-Butyldimethylsilyloxy-2'-deoxyguanosine, a modified guanosine, is a pivotal compound in biomedical research, facilitating DNA synthesis. It provides an ideal substrate for DNA polymerases while also being a key ingredient in nucleic acids chemistry, useful in exploring the relationship between DNA damage and cancer. Additionally, its application as a tool to focus on the structure-function links of DNA-repair enzymes has been extensive, unveiling novel research opportunities. Synonyms: 5'-O-TBDMS-2'-deoxyguanosine; 2-Amino-9-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 5'-O-TBDMS-dG; 2'-Deoxy-5'-O-[dimethyl(2-methyl-2-propanyl)silyl]guanosine. Grades: ≥97% by HPLC. CAS No. 51549-33-8. Molecular formula: C16H27N5O4Si. Mole weight: 381.51.
6-Methyl-thio-guanosine
6-Methyl-thio-guanosine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg, 200mg. US Biological Life Sciences.
Worldwide
6-Methyl-thio-guanosine
6-Methyl-thio-guanosine is a remarkable biomedical concoction widely employed as a nucleoside analog in research of viral infestations, namely hepatitis C and influenza. Displays a formidable arsenal of antiviral capabilities, it efficaciously impedes viral recompoundion through its assimilation into the viral RNA strand, thereby forestalling the intricate process of enhancement. Synonyms: 2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine; 9H-Purin-2-amine, 6-(methylthio)-9-beta-D-ribofuranosyl-; 6-Methylthioguanosine; (2R,3R,4S,5R)-2-(2-amino-6-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-Amino-6-methylthiopurine ribonucleoside. Grades: ≥95%. CAS No. 4914-73-2. Molecular formula: C11H15N5O4S. Mole weight: 313.33.
6-Methylthio-guanosine
6-Methylthio-guanosine, a petite molecule, offers a vantage point for investigating the intricate interplay between post-transcriptional modification and gene expression. Its structural resemblance to S-adenosylmethionine, along with a demonstrated impact on mRNA transcript stabilization and translation regulation, hold immense value for scientific investigations. Furthermore, its potential therapeutic applications in treating viral infections and cancer open up new avenues of exploration for the scientific community. Grades: ≥ 98%. Molecular formula: C11H15N5O4S. Mole weight: 313.33.
6-O-MethylGuanosine
6-O-MethylGuanosine is a modified nucleoside [1]. 6-O-MethylGuanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7803-88-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-111648.
7-Methyl-6-thioguanosine
7-Methyl-6-thioguanosine, a well-known compound in the field of biomedicine, exhibits potent antiviral attributes. Its application shines specifically in addressing RNA virus-induced ailments, such as hepatitis C and selective respiratory viruses. Bolstering immunological reaction while restraining viral duplication, this invaluable resource elevates significance in the realms of biomedical investigations and pharmaceutical advancements. Synonyms: MESG; 6-Mercapto-7-methylguanosine; 7-Methyl-6-thioguanosine; 55727-10-1; 2-Amino-6-mercapto-7-methylpurine ribonucleoside; 5F1954X1MN; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methylpurin-9-ium-6-thiolate; 7-methyl-6-Thioguanosine (technical grade); UNII-5F1954X1MN; Guanosine, 7-methyl-6-thio-; CHEMBL1234483; 6-THIO-7-METHYLGUANOSINE; DTXSID601235975; AKOS040744092; 2-Amino-6,9-dihydro-7-methyl-9-beta-D-ribofuranosyl-6-thioxo-1H-purinium hydroxide, inner salt; PD018378; Q27261945; 2-amino-7-methyl-9-beta-D-ribofuranosyl-9H-purin-7-ium-6-thiolate; 1H-PURINIUM, 2-AMINO-6,9-DIHYDRO-7-METHYL-9-.BETA.-D-RIBOFURANOSYL-6-THIOXO-, INNER SALT; 1H-Purinium, 2-amino-6,9-dihydro-7-methyl-9-beta-D-ribofuranosyl-6-thioxo-, hydroxide, inner salt. Grades: ≥ 75%. CAS No. 55727-10-1. Molecular formula: C11H15N5O4S. Mole weight: 313.34.
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