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(5E)-7-[(1R,2R,3R,5S)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(1E,3S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide is one of bimatoprost intermediates. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: (5E)-7-{(1R,2R,3R,5S)-3,5-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-[(1E,3S)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-5-phenyl-1-penten-1-yl]cyclopentyl}-N-ethyl-5-heptenamide; 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(1E,3S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5E)-. Molecular formula: C43H79NO4Si3. Mole weight: 758.35.
5-Methyl-2-hepten-4-one
5-Methyl-2-hepten-4-one. Group: Biochemicals. Grades: Highly Purified. CAS No. 81925-81-7. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C8H14O. US Biological Life Sciences.
A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: E-Carboxyterbinafine, (5E) -2, 2-Dimethyl-7-[methyl (1-naphthalenylmethyl) amino]-5-hepten-3-ynoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A deuterated metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-7-[(1-naphthalenyl-d7-methyl)amino]-(5E)-5-hepten-3-ynoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
A deuterated intermediate in the synthesis of the metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-7-[(1-naphthalenyl-d7-methyl)amino]-(5E)-5-hepten-3-ynoic Acid, Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: N- [ (2E) -6, 6-Di methyl -2-hepten-4-ynyl] -1-naphthalene methanamine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Group: Biochemicals. Alternative Names: Lamisil, N- [ (2E) -6, 6-Di methyl -2-hepten-4-ynyl] -N- methyl -1-naphthalene methanamine. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
an impurity of Limaprost. Synonyms: (2E)-7-[(1R,2R)-2-[(1E,3S,5S)-3-Hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-2-heptenoic Acid. Grades: > 95%. CAS No. 853998-93-3. Molecular formula: C22H36O4. Mole weight: 364.53.
15-epi-Travoprost
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. CAS No. 1420791-14-5. Molecular formula: C26H35F3O6. Mole weight: 500.56.
15-Keto latanoprost
15-Keto latanoprost. Group: Biochemicals. Alternative Names: (5Z) -7-[ (1R, 2R, 3R, 5S) -3, 5-Dihydroxy-2- (3-oxo-5-phenylpentyl) cyclopentyl]-5-heptenoic acid 1-methylethyl ester. Grades: Highly Purified. CAS No. 135646-98-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C26H38O5. US Biological Life Sciences.
Worldwide
15-Keto Latanoprost
a metabolite of Latanoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; [1R-[1α(Z), 2β, 3α, 5α]]-7-[3, 5-Dihydroxy-2-(3-oxo- 5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. Grades: > 95%. CAS No. 135646-98-9. Molecular formula: C26H38O5. Mole weight: 430.59.
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; 15-keto Fluprostenol Isopropyl Ester. CAS No. 404830-45-1. Molecular formula: C26H33F3O6. Mole weight: 498.54.
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 value for the free acid forms of 15(R)-17-phenyl trinor PGF2α wa determined to be 30 nM in a FP receptor binding assay using the cat iris sphincter muscle. Synonyms: 9α,11α,15R-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester; 15-epi Bimatoprost isopropylester; 15(R)-Bimatoprost isopropyl ester; 15(R)-17-phenyl trinor PGF2α isopropyl ester; Isopropyl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenoate; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-. Grades: 98%. CAS No. 130273-87-9. Molecular formula: C26H38O5. Mole weight: 430.59.
It is an impurity of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Synonyms: (3S,6R)-2,3-Dimethyl-6-[(1R,3aalpha)-4beta-hydroxy-7abeta-methylhydrindane-1beta-yl]-4-heptene-2-ol; Paricalcitol Impurity A01. CAS No. 95716-67-9. Molecular formula: C19H34O2. Mole weight: 294.47.
(3R,5R)-Rosuvastatin Calcium is a derivative of Rosuvastatin, a statin medication used to treat cardiovascular disease. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt. CAS No. 1422515-55-6. Molecular formula: C44H54CaF2N6O12S2. Mole weight: 1001.14.
(3R,5R)-Rosuvastatin Methyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester. Grades: > 95%. CAS No. 1776088-23-3. Molecular formula: C23H30FN3O6S. Mole weight: 495.57.
(3R,5R)-Rosuvastatin Sodium Salt
An enantiomer of Rosuvastatin used for treatment, prevention and combination therapy of lipid-related disorders. Group: Biochemicals. Alternative Names: (3R, 5R, 6E)-7-[4- (4-Fluorophenyl)-6- (1-methylethyl)-2-[methyl (methylsulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy-6-heptenoic Acid Sodium. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
(3R,5R)-Rosuvastatin Sodium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester is an intermediate in the synthesis of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (3R,5S,E)-Tert-butyl 7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Pitavastatin Impurity compound C; 2-Methyl-2-propanyl (3R,5S,6E)-7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoate; 6-Heptenoic acid, 7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-. Grades: 97%. Molecular formula: C29H33NO4. Mole weight: 459.58.
An intermediate for the preparation of (3R,5S)-Fluvastatin. Group: Biochemicals. Alternative Names: (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 194934-96-8. Pack Sizes: 1mg. US Biological Life Sciences.
(3S,5R)-Fluvastatin sodium salt. Group: Biochemicals. Alternative Names: (3S,5R)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt. Grades: Highly Purified. CAS No. 155229-76-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H25FNNaO4. US Biological Life Sciences.
Worldwide
(3S,5S)-Fluvastatin Sodium Salt
(3S,5S)-Fluvastatin Sodium Salt is an analogue of Fluvastatin (F601250). Synonyms: (S,S)-Fluvastatin Sodium Salt; [S-[R*,R*-(E)]]-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Monosodium Salt. Grades: > 95%. CAS No. 194935-01-8. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
(3S,5S)-Rosuvastatin Sodium Salt
An impurity of Rosuvastatin salt.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: Rosuvastatin (3S,5S)-Isomer Sodium ;(3S, 5S)-Rosuvastatin Sodium ;Enantiomer of (3R,5R)-Rosuvastatin Sodium ;(3S,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid sodium salt. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
5,19-Epoxy-3,14-viscidadien-16 oic acid
5,19-Epoxy-3,14-viscidadien-16 oic acid is a compound obtained from Myoporaceae sp. Synonyms: 2-Heptenoic acid, 6-(3,6,7,8,9,9a-hexahydro-4-methyl-1H-3,6a-methanocyclopent[c]oxocin-7-yl)-2-methyl-, [3R- [3α, 6aα, 7β(R*), 9aβ]]-. CAS No. 110623-88-6. Molecular formula: C20H30O3. Mole weight: 318.45.
5,6-trans-Travoprost
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5E)-7-[(1R,3R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. CAS No. 1563176-59-9. Molecular formula: C26H35F3O6. Mole weight: 500.56.
5-trans-Latanoprost
an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Synonyms: (5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. Grades: > 95%. CAS No. 913258-34-1. Molecular formula: C26H40O5. Mole weight: 432.60.
AL 8810 isopropyl ester
AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost and Travoprost. Synonyms: AL 8810 isopropyl ester; Propan-2-yl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoate; 5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-; HMS3648C21; AKOS025294879; SR-01000946200; SR-01000946200-1; 9alpha, 15R- dihydroxy- 11beta- fluoro- 15- (2, 3- dihydro- 1H- inden- 2- yl)- 16, 17, 18, 19, 20- pentanor- prosta- 5Z, 13E- dien- 1- oic acid, isopropyl ester. Grades: ≥98%. CAS No. 208114-93-6. Molecular formula: C27H37FO4. Mole weight: 444.6.
Alternaric acid
It is produced by the strain of Alternaria solani. The main antifungal activity was 0.1-1.0 ?/mL, which inhibited the spore germination of Plomonas aeruginosa, Porphyra porphyra and Black grapevine panicle. Synonyms: D-Arabinonic acid,4,5-dideoxy-2-C-((1E)-7-((6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-4-methylene-7-oxo-1-heptenyl)-4-ethyl; 3-Nonenoic acid,9-(5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-9-oxo-,(6R-(3(2S*(1R*,2S*),3E),6R*)); 3-Octenoic acid,2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-8-[(tetrahydro-6-methyl-2,4-dioxopyran-3-yl)carbonyl]-(8CI); Alternaric acid (6CI,7CI); D-Arabinonic acid,4,5-dideoxy-2-C-[(1E)-7-[(6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl]-4-methylene-7-oxo-1-heptenyl]-4-ethyl-(9CI). Grades: 98%. CAS No. 10088-62-7. Molecular formula: C21H30O8. Mole weight: 410.46.
Arbozol
Heterocyclic Organic Compound. Alternative Names: ARBOZOL;BICYCLO[2.2.1]HEPT-5-ENE-2-METHANOL,5,6-DIMETHYL-1-(1-METHYLETHENYL)-;5,6-Dimethyl-1-isopropenylbicyclo[2.2.1]-5-heptene-2-methanol;5,6-Dimethyl-(1-methylethenyl)bicyclo(2.2.1)hept-5-ene-2-methanol. CAS No. 110458-85-0. Molecular formula: C13H20O. Mole weight: 192.3. Catalog: ACM110458850.
Atorvastatin 3-Deoxyhept-2E-Enoic Acid
Atorvastatin 3-Deoxyhept-2E-Enoic Acid is an impurity of Atorvastatin, which is an HMG-CoA reductase inhibitor used to reduce cholesterol and prevent cardiovascular-related disease. Synonyms: (S,E)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-5-hydroxyhept-2-enoic acid; Atorvastatin 3-deoxyhept-2-enoic acid; (2E)-2,3-Dehydroxy Atorvastatin; 2-Heptenoic acid, 7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-, (2E,5S)-; (2E,5S)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-2-heptenoic acid. Grades: ≥95%. CAS No. 1105067-93-3. Molecular formula: C33H33FN2O4. Mole weight: 540.64.
An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: (2E)-2,3-Dehydroxy Atorvastatin calcium; (2E,5S)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-2-heptenoic Acid calcium salt. Grades: > 95%. Molecular formula: C66H64F2N4O8Ca. Mole weight: 1119.33.
Bimatoprost Acid Methyl Ester
Bimatoprost Acid Methyl Ester is an impurity of the antiglaucoma agent Bimatoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; 17-Phenyl-18,19,20-trinor-PGF2α Methyl Ester. Grades: > 95%. CAS No. 38315-47-8. Molecular formula: C24H34O5. Mole weight: 402.54.
Brefeldin a
Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator. Brefeldin A inhibits HSV-1 and has anti-cancer activity. Group: Inhibitors. Alternative Names: NECTROLIDE; SYNERGISIDIN; 4h-cyclopent(f)oxacyclotridecin-4-one, 1, 6, 7, 8, 9, 11a-beta, 12, 13, 14, 14a-alpha-de; cahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-; cyanaein; CYANEIN; DECUMBIN; GAMMA-4-DIHDYROXY-2-(6-HYDROXY-1-HEPTENYL)-4-CYCLOPENTANECROTONIC ACID LAMBDA-LACTONE. CAS No. 20350-15-6. Molecular formula: C16H24O4. Mole weight: 280.36. Purity: 0.9987. Catalog: ACM20350156.
Carboxy terbinafine
Carboxy terbinafine. Group: Biochemicals. Alternative Names: (5E) -2, 2-Dimethyl-7-[methyl (1-naphthalenylmethyl) amino]-5-hepten-3-ynoic acid; Carboxybutyl terbinafine; E-Carboxyterbinafine. Grades: Highly Purified. CAS No. 99473-14-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C21H23NO2. US Biological Life Sciences.
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