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2-Methyl-4-hydroxypyridine is used in the synthesis of novel indolizine compounds as inhibitors of phosphodiesterase IV. Also used in the preparation of 2-substituted imidazole ring compoiunds for treatment againast human African trypanosomiasis. Group: Biochemicals. Alternative Names: 2-Methylpyridin-4-ol; 4-Hydroxy-2-methylpyridine; 2-Methyl-4-pyridinol. Grades: Highly Purified. CAS No. 18615-86-6. Pack Sizes: 1g. Molecular Formula: C?H?NO, Molecular Weight: 109.13. US Biological Life Sciences.
3-Hydroxy-1-methylpyridinium Iodide is a hydroxypyridine derivative showed protective effects of human erythrocytes against hemolysis from mechanical trauma. 3-Hydroxy-1-methylpyridinium Iodide is an antioxidant that showed inhibitory activity towards respiratory chain mitochondria. Group: Biochemicals. Alternative Names: 1-Methyl-3-hydroxypyridinium Iodide; 3-Hydroxypyridinium Methiodide. Grades: Highly Purified. CAS No. 7500-5-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
3-hydroxy-2-methylpyridinecarboxylate dioxygenase
A flavoprotein (FAD). Group: Enzymes. Synonyms: methylhydroxypyridinecarboxylate oxidase; 2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase; methylhydroxypyridine carboxylate dioxygenase; 3-hydroxy-3-methylpyridinecarboxylate dioxygenase [incorrect]; 3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.14.12.4. CAS No. 37256-69-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0693; 3-hydroxy-2-methylpyridinecarboxylate dioxygenase; EC 1.14.12.4; 37256-69-2; methylhydroxypyridinecarboxylate oxidase; 2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase; methylhydroxypyridine carboxylate dioxygenase; 3-hydroxy-3-methylpyridinecarboxylate dioxygenase [incorrect]; 3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing). Cat No: EXWM-0693.
4-Trifluoromethylpyridin-2-ol. Group: Biochemicals. Alternative Names: 2-Hydroxy-4-trifluoro methyl pyridine; 4-Trifluoromethyl-1H-pyridin-2-one; 4-Trifluoromethyl-2(1H)-pyridinone; 4-Trifluoromethyl-2-hydroxypyridine; 4-Trifluoromethyl-2-pyridinone; 4-Trifluoromethyl-2-pyridone. Grades: Highly Purified. CAS No. 50650-59-4. Pack Sizes: 1g. Molecular Formula: C6H4F3NO, Molecular Weight: 163.1. US Biological Life Sciences.
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Emoxipine
Emoxipine. Group: Biochemicals. Alternative Names: 2-Ethyl-6-methyl-3-pyridinol; 2-Ethyl-3-hydroxy-6-methylpyridine; 2-Ethyl-6-methyl-3-hydroxypyridine. Grades: Highly Purified. CAS No. 2364-75-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H11NO. US Biological Life Sciences.
Worldwide
Pirbuterol acetate
Pirbuterol acetate is a short-acting β2 adrenoreceptor agonist. It has bronchodilating action and is used as a bronchodilator. It is also used in the treatment of asthma as a breath-activated metered-dose inhaler. It was developed by Valeant and has been listed. Uses: Pirbuterol acetate has bronchodilating action and is used as a bronchodilator. it is also used in the treatment of asthma as a breath-activated metered-dose inhaler. Synonyms: Alpha-6-[(tert-butylamino)methyl]-3-hydroxypyridine-2,6-dimethanol monoacetate;(RS)-2-(tert-Butylamino)-1-(6-hydroxymethyl-5-hydroxy-2-pyridyl)ethanol acetate salt;6-(2-Tert-Butylamino-1-hydroxyethyl)-2-hydroxymethylpyridin-3-ol acetate. Grades: 95%. CAS No. 65652-44-0. Molecular formula: C14H24N2O5. Mole weight: 300.35.
1-Methyl-2-ethyl-3-hydroxypyridin-4-one
Heterocyclic Organic Compound. CAS No. 115864-73-8. Catalog: ACM115864738.
2'-b-C-Methyl-3-deazauridine
2'-b-C-Methyl-3-deazauridine is a potential antiviral and anticancer agent. It is a prodrug of the active metabolite 2'-C-methylguanosine, which can be incorporated into viral RNA or DNA leading to inhibition of viral replication. Additionally, 2'-b-C-Methyl-3-deazauridine has been shown to inhibit tumor growth in vitro and in vivo and has potential as a chemotherapy drug for various types of cancer. Synonyms: 4-Hydroxy-1-(2-b-C-methyl-b-D-ribofuranosyl)-2(1H)-pyridinone; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-4-hydroxypyridin-2(1H)-one. Grades: ≥95%. CAS No. 622379-93-5. Molecular formula: C11H15NO6. Mole weight: 257.24.
(2R,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-((3-Fluoro-6-hydroxypyridin-2-yl)amino)-1,3-oxathiolane-2-carboxylate is an impurity of Emtricitabine (E525000), a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H27FN2O4S, Molecular Weight: 398.49. US Biological Life Sciences.
(2R,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-((3-Fluoro-6-hydroxypyridin-2-yl)amino)-1,3-oxathiolane-2-carboxylate is an impurity of Emtricitabine, which is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Molecular formula: C19H27FN2O4S. Mole weight: 398.49.
3-? ( (4-?Methylpiperazin-?1-?yl) ?methyl) ?benzonitrile is involved in the preparation of N- hydroxyphenyl acryl amide s and N-Hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 859850-90-1. Pack Sizes: 50mg, 100mg. Molecular Formula: C13H17N3, Molecular Weight: 215.29. US Biological Life Sciences.
AN0128, also known as CRM-0005 and ONT-0001, is a tumour necrosis factor alpha (TNF-α) inhibitor potentially for the treatment of atopic dermatitis. AN0128 showed promising combination of anti-bacterial and anti-inflammatory activities. This compound is now in clinical development for dermatological conditions. Daily application of AN0128 (1%) compared with controls reduced bone loss by 38 to 44% (P < 0.05), while vehicle alone had no effect (P> 0.05). The reduction in bone loss with AN0128 was similar to that achieved with a NSAID, ketorolac, and Total toothpaste containing triclosan. AN0128 also reduced the level of gingival inflammation 42% compared with the ligature only (P < 0.05), whereas vehicle alone had no effect (P> 0.05). The results indicate that AN0128 significantly reduces the formation of an inflammatory infiltrate and reduces bone loss, measured histologically and by micro-CT. Group: Inhibitors. Alternative Names: AN-0128; CRM-0005; ONT-0001; AN0128; CRM0005; ONT0001; AN 0128; CRM 0005; ONT 0001. CAS No. 872044-70-7. Molecular formula: C20H16BCl2NO3. Mole weight: 400.06. Appearance: Solid powder. Purity: >98%. IUPACName: ((bis(3-chloro-4-methylphenyl)boraneyl)oxy)(3-hydroxypyridin-2-yl)methanone. Canonical SMILES: CC1=CC=C (B (OC (C2=NC=CC=C2O)=O)C3=CC=C (C)C (Cl)=C3)C=C1Cl. Catalog: ACM872044707.
Lasmiditan Impurity 16 (Hydrobromide)
Lasmiditan Impurity 16 (Hydrobromide). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6-hydroxypyridin-2-yl)(1-methylpiperidin-4-yl)methanone hydrobromide. Molecular Formula: C12H16N2O2·HBr. Mole Weight: 300.05. Catalog: APB01532.
Nikkomycin Z from Streptomyces tendae
Nikkomycin Z is a nucleotide peptide from Streptomyces tendae with antifungal effects. Nikkomycin Z is a selective and competitive inhibitor of chitin synthesis and acts as a competitive analog of the chitin synthetase substrate UDP-N-acetylglucosamine. Synonyms: Nikkomycin; Neopolyoxin C; β-D-Allofuranuronic acid, 5-[[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1,5-dideoxy-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-; (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-β-D-allo-furanuronic acid. Grades: ≥90% by HPLC. CAS No. 59456-70-1. Molecular formula: C20H25N5O10. Mole weight: 495.44.
Pyridostigmine bromide
Pyridostigmine bromide is a parasympathomimetic and a reversible cholinesterase inhibitor used to treat myasthenia gravis and reverse the effects of muscle relaxants. Synonyms: Pyridinium, 3-[[(dimethylamino)carbonyl]oxy]-1-methyl-, bromide (1:1); Kalimin; Kalymin; Mestinon; Mestinon Bromide; NSC 679759; Piridostigmin; 3-Hydroxy-1-methylpyridinium bromide, dimethylcarbamate; Carbamic acid, dimethyl-, ester with 3-hydroxy-1-methylpyridinium bromide; Pyridinium, 3-[[(dimethylamino)carbonyl]oxy]-1-methyl-, bromide; Pyridinium, 3-hydroxy-1-methyl-, bromide, dimethylcarbamate; 1-Methyl-3-hydroxypyridinium bromide dimethylcarbamate; 3-(Dimethylcarbamoyloxy)-1-methylpyridinium bromide; 3-(Dimethylcarbamyloxy)-1-methylpyridinium bromide; 3-[[(Dimethylamino)carbonyl]oxy]-1-methylpyridinium bromide; Regonol; Ro 1-5130. Grades: >98%. CAS No. 101-26-8. Molecular formula: C9H13BrN2O2. Mole weight: 261.12.
Pyridostigmine Bromide
Cholinergic, used in the treatment of myasthenia gravis, and is a pre-exposure antidote to chemical warfare agents. Group: Biochemicals. Alternative Names: 3-[[ (Dimethylamino) carbonyl]oxy]-1-methyl-pyridinium Bromide; 3-Hydroxy-1-methylpyridinium Bromide Dimethylcarbamate; 1-Methyl-3-hydroxypyridinium Bromide Dimethylcarbamate; 3-[[ (Dimethylamino) carbonyl]oxy]-1-methylpyridinium Bromide; Kalimin; Kalymin; Mestinon; Mestinon Bromide; NSC 679759; Piridostigmin. Grades: Highly Purified. CAS No. 101-26-8. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Siderochelin B
It is produced by the strain of Nocardia sp. SC 113, Act. sp. 69-209B-89. It has only weak effect against individual strains, such as E. coli. Synonyms: (2R)-3,4-Dihydro-4β-hydroxy-5-(3-hydroxypyridin-2-yl)-4-methyl-2H-pyrrole-2β-carboxamide. CAS No. 77518-26-4. Molecular formula: C11H13N3O3. Mole weight: 235.24.
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