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An intermediate in the preparation of Ondansetron impurities and organic polymers. Group: Biochemicals. Alternative Names: 1,1'-(Methylenedi-p-phenylene)dihydrazine DiHydrochloride; 4, 4'-Di hydrazinodiphenyl methane Hydrochloride. Grades: Highly Purified. CAS No. 100829-65-0. Pack Sizes: 250mg. US Biological Life Sciences.
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2- [ (4-Chloro phenyl ) methy l ene ]-N-methylhydrazinecar bothioamide
2- [ (4-Chloro phenyl ) methy l ene ]-N-methylhydrazinecar bothioamide , is an amino acid derivative that can be used as a potential antitubercular (combats tuberculosis bacteria) drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 10444-72-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H10ClN3S, Molecular Weight: 227.71. US Biological Life Sciences.
Worldwide
2- [ (4-Ethyl phenyl ) methyl ene ]-N-methylhydrazinecar bothioamide
2- [ (4-Ethyl phenyl ) methyl ene ]-N-methylhydrazinecar bothioamide is a thiacetazone analog and a mycolic acid biosynthesis inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 386255-47-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H15N3S, Molecular Weight: 221.32. US Biological Life Sciences.
Worldwide
2- [ (4-Ethyl phenyl ) methyl ene ]-N-phenylhydrazinecarbo thioamide
2- [ (4-Ethyl phenyl ) methyl ene ]-N-phenylhydrazinecarbo thioamide (cas# 691395-41-2) is a compound useful in organic synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 691395-41-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C16H17N3S, Molecular Weight: 283.39. US Biological Life Sciences.
Worldwide
2- [ (4-Fluoro phenyl ) methy l ene ]-N-methylhydrazinecar bothioamide
2- [ (4-Fluoro phenyl ) methy l ene ]-N-methylhydrazinecar bothioamide (cas# 301201-62-7) is a compound useful in organic synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 301201-62-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H10FN3S, Molecular Weight: 211.26. US Biological Life Sciences.
(2E) -2- [ (4-Ethyl phenyl ) methyl ene ] hydrazinecarb othioamide is used in skin whitening compounds, as it inhibits the generation of melanins. Group: Biochemicals. Grades: Highly Purified. CAS No. 1334179-95-1. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H13N3S, Molecular Weight: 251.55. US Biological Life Sciences.
Worldwide
(2E) -2- [ (4-methylphenyl ) met hyl ene ] hydrazinec arbothioamide
(2E) -2- [ (4-methylphenyl ) met hyl ene ] hydrazinec arbothioamide is used in skin whitening compounds, as it inhibits the generation of melanins. Group: Biochemicals. Grades: Highly Purified. CAS No. 1321617-35-9. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H11N3S, Molecular Weight: 193.27. US Biological Life Sciences.
Worldwide
(2E) -2- [ (4-methylphenyl ) met hyl ene ]-N-phenylhydrazinecarbo thioamide
(2E) -2- [ (4-methylphenyl ) met hyl ene ]-N-phenylhydrazinecarbo thioamide is used in the preparation of triazole thiones and triazoles via copper-catalyzed oxidative heterocyclization of arylidene arylthiosemicarbazide s. Group: Biochemicals. Grades: Highly Purified. CAS No. 1807960-36-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C15H15N3S, Molecular Weight: 269.36. US Biological Life Sciences.
Worldwide
(2E) -N- methyl -2- [ (4-methylphenyl ) met hyl ene ] hydrazinec arbothioamide
(2E) -N- methyl -2- [ (4-methylphenyl ) met hyl ene ] hydrazinec arbothioamide is prepared in reaction of 4-methylbenzaldehyde and 4- methyl thiosemicarbazide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1262832-60-9. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H13N3S, Molecular Weight: 207.3. US Biological Life Sciences.
[2-Fluoro-4- (methylsulfonyl) phenyl]hydrazine. Group: Biochemicals. Grades: Highly Purified. CAS No. 832714-48-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H9FN2O2S, Molecular Weight: 204.22. US Biological Life Sciences.
Worldwide
3-Trifluoro methylphenylhydrazine Hydrochloride
3-Trifluoro methylphenylhydrazine Hydrochloride, is an intermediate in the synthesis of pharmaceutical compounds including inhibitors, and anticancer agents. It is used in the synthesis of isosteviol-fused pyrazolines and pyrazoles as potential anticancer agents. Group: Biochemicals. Alternative Names: (α, α, α-trifluoro-m-tolyl)hydrazine Hydrochloride; [3- (trifluoromethyl) phenyl]hydrazine Monohydrochloride. Grades: Highly Purified. CAS No. 3107-33-3. Pack Sizes: 5g. US Biological Life Sciences.
2-(Methylamino)-1-phenylethanol is a reagent used in the synthesis of novel hydrazine inhibitors for human vascular adhesion protein-1. Group: Biochemicals. Grades: Highly Purified. CAS No. 6589-55-5. Pack Sizes: 250mg, 1g. Molecular Formula: C9H13NO, Molecular Weight: 151.21. US Biological Life Sciences.
Aprepitant Impurity 47. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)-1-iminoethyl)hydrazinecarboxylate. CAS No. 219821-37-1. Molecular Formula: C24H25F7N4O4. Mole Weight: 566.47. Catalog: APB219821371.
Carfilzomib Impurity 42
Carfilzomib Impurity 42. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S,2S,2'S)-N,N'-((2S,2'S)-hydrazine-1,2-diylbis(1-oxo-3-phenylpropane-2,1-diyl))bis(4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide). Molecular Formula: C62H84N10O10. Mole Weight: 1129.39. Catalog: APB04735.
Co 102862
Co 102862, also known as V102862, an orally active anticonvulsant with robust activity, is a potent, broad-spectrum state-dependent inhibitor of mammalian voltage-gated Na+ channels with ~ 80-fold higher affinity for inactivated Na+ channels compared to channels in the resting state. Synonyms: CO-102862; CO 102862; CO102862; [[4- (4-fluorophenoxy) phenyl]methylideneamino]urea; 4-(4-fluorophenoxy)benzaldehyde semicarbazone; Co 102862; Co-102862; FPhOBal semicarbazone; 181144-66-1; 2- (4- (4-Fluorophenoxy) benzylidene) hydrazinecarboxamide; Hydrazinecarboxamide, 2-[[4-(4-fluorophenoxy)phenyl]methylene]-. Grades: >99 %. CAS No. 181144-66-1. Molecular formula: C14H12FN3O2. Mole weight: 273.26.
An intermediate for the synthesis of Atazanavir-d5. Group: Biochemicals. Alternative Names: 2- [ (2S, 3S) -3- [ [ (1, 1-Dimethylethoxy) carbonyl] amino] -2-hydroxy-4-phenyl-d5-butyl] -2- [ [4- (2-pyridinyl) phenyl] methyl] hydrazinecarboxylic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
flavin-containing monooxygenase
A flavoprotein. A broad spectrum monooxygenase that accepts substrates as diverse as hydrazines, phosphines, boron-containing compounds, sulfides, selenides, iodide, as well as primary, secondary and tertiary amines. This enzyme is distinct from other monooxygenases in that the enzyme forms a relatively stable hydroperoxy flavin intermediate. This microsomal enzyme generally converts nucleophilic heteroatom-containing chemicals and drugs into harmless, readily excreted metabolites. For example, N-oxygenation is largely responsible for the detoxification of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Group: Enzymes. Synonyms: dimethylanilin...CAS No. 37256-73-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0887; flavin-containing monooxygenase; EC 1.14.13.8; 37256-73-8; dimethylaniline oxidase; dimethylaniline N-oxidase; FAD-containing monooxygenase; N,N-dimethylaniline monooxygenase; DMA oxidase; flavin mixed function oxidase; Ziegler's enzyme; mixed-function amine oxidase; FMO; FMO-I; FMO-II; FMO1; FMO2; FMO3; FMO4; FMO5; flavin monooxygenase; methylphenyltetrahydropyridine N-monooxygenase; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase; dimethylaniline monooxygenase (N-oxide-forming). Cat No: EXWM-0887.
The Dmab group can be cleaved selectively in the presence of tBu-based protected groups by treatment with 2% hydrazine in DMF, making this derivative an extremely useful tool for the preparation of cyclic peptides by FMOC SPPS. Synonyms: Fmoc-L-Asp(ODmab)-OH; Fmoc-Asp(ODmab)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartic acid 4-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methyl] ester. Grades: ≥ 99.5% (Chiral HPLC). CAS No. 269066-08-2. Molecular formula: C39H42N2O8. Mole weight: 666.70.
Isocarboxazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) belonging to the hydrazine class. It is primarily used to treat mood and anxiety disorders. It is also used for the treatment of Parkinson's disease and other dementia-related disorders. It is also effective in the treatment of major depression, dysthymic disorder, and atypical depression. It blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO, thereby increasing the concentrations of norepinephrine and 5-hydroxytrytamine at central aminergic receptors. It was developed by Validus and has been listed. Uses: Isocarboxazid is primarily used to treat mood and anxiety disorders. it is also used for the treatment of parkinson's disease and other dementia-related disorders. it is also effective in the treatment of major depression, dysthymic disorder, and atypical. Synonyms: 1-Benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine;3-Isoxazolecarboxylic acid, 5-methyl-, 2-(phenylmethyl)hydrazide;3-Isoxazolecarboxylic acid, 5-methyl-, 2-benzylhydrazide;5-Methyl-3-isoxazole-carboxylic Acid 2-Benzylhydrazide;3-(N-Benzylhydrazinocarbon. Grades: 95%. CAS No. 59-63-2. Molecular formula: C12H13N3O2. Mole weight: 231.25.
N- (4-Diethylaminobenzylideneamino) guanidine acetic acid salt
Heterocyclic Organic Compound. Alternative Names: 2- [ [4- (Diethylamino) phenyl] methylene] hydrazinecarboximidamide Acetate. CAS No. 1185244-51-2. Molecular formula: C14H23N5O2. Mole weight: 293.36. Appearance: Off-White to Light Green Solid. Purity: 0.96. IUPACName: acetic acid; 2-[[4- (diethylamino) phenyl]methylideneamino]guanidine. Catalog: ACM1185244512.
S 25585
S 25585 is a potent neuropeptide Y (NPY) Y5 receptor antagonist (IC50 = 5.4, > 1000, > 10 000 and > 10 000 nM at Y5, Y1, Y2 and Y4 receptors, respectively) without affinity for a wide range of other receptors. S 25585 significantly inhibits NPY-induced feeding but not through blockade of Y5 receptors. Synonyms: S 25585; S-25585; S25585; 1-Benzoyl-2- [ [trans-4- [ [ [ [2-nitro-4- (trifluoromethyl) phenyl] sulfonyl] amino] methyl] cyclohexyl] carbonyl] hydrazine; N-[[4- (benzamidocarbamoyl) cyclohexyl]methyl]-2-nitro-4- (trifluoromethyl) benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 263849-50-9. Molecular formula: C22H23F3N4O6S. Mole weight: 528.5.
Aprepitant Impurity 50. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-methyl (2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)-1-hydrazinylethylidene)carbamate. Molecular Formula: C24H25F7N4O4. Mole Weight: 566.47. Catalog: APB02495.
Atazanavir EP Impurity I
Atazanavir EP Impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((S)-1-(((2S,3S)-3-hydroxy-1-phenyl-4-((E)-1-(4-(pyridin-2-yl)benzyl)-2-(4-(pyridin-2-yl)benzylidene)hydrazinyl)butan-2-yl)amino)-3,3-dimethyl-1-oxobutan-2-yl)carbamate. Molecular Formula: C42H46N6O4. Mole Weight: 698.85. Catalog: APB03262.
Bizine hydrochloride
Bizine hydrochloride is a potent and selective histone demethylase LSD1 inhibitor. Bizine can modulate bulk histone methylation in cancer cells and protect neurons exposed to oxidative stress, suggesting potential applications in neurodegenerative disease. Uses: Potential neurodegenerative disease therapy. Synonyms: N-[4-(2-hydrazinylethyl)phenyl]-4-phenylbutanamide hydrochloride. Grades: 98%. Molecular formula: C18H23N3O.HCl. Mole weight: 333.86.
CGP-75355
CGP-75355 is an HIV Protease inhibitor (EC50= 0.7 nM). Uses: Hiv protease inhibitors. Synonyms: CGP-75355; CGP 75355; CGP75355; UNII-4ZE7DBE752; methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-phenylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate; 232632, BMS; 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester; atazanavir; atazanavir sulfate; BMS 232632; BMS 232632 05; BMS-232632; BMS-232632-05; BMS232632; BMS23263205. Grades: >98%. CAS No. 191594-64-6. Molecular formula: C39H53N5O7. Mole weight: 703.87.
Dantrolene Impurity 3
2-[1-(Aminocarbonyl)-2-[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazinyl]-acetic Acid Ethyl Ester is an intermediate used in the synthesis of 1-(5-Phenylfurfurylideneamino)hydantoins. Synonyms: 2-[1-(Aminocarbonyl)-2-[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazinyl]-acetic Acid Ethyl Ester. Grades: > 95%. CAS No. 55227-60-6. Molecular formula: C16H16N4O6. Mole weight: 360.32.
An intermediate for the synthesis of Atazanavir. Group: Biochemicals. Alternative Names: (αS, βS)- β -Amino-α - [ [1- [ [4- (2-pyridinyl) phenyl] methyl] hydrazino] methyl] benzenepropanol Trihydrochloride; [S-(R*,R*)]- β -Amino-α - [ [1- [ [4- (2-pyridinyl) phenyl] methyl] hydrazino] methyl] benzenepropanol Trihydrochloride. Grades: Highly Purified. CAS No. 198904-87-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
DIRECT PURE YELLOW 5G
Direct Dyes. Alternative Names: DIRECT PURE YELLOW 5G; Coomassie Yellow 6G; Direct Pure Yellow; Acid Yellow 186. CAS No. 10130-29-7. Molecular formula: C24H19N4NaO5S2. Mole weight: 530.55. Purity: 0.96. IUPACName: sodium 2-[4-[2-(1-anilino-1,3-dioxobutan-2-ylidene)hydrazinyl]phenyl]-6-methyl-1,3-benzothiazole-7-sulfonate. Canonical SMILES: CC1=C (C2=C (C=C1)N=C (S2)C3=CC=C (C=C3)NN=C (C (=O)C)C (=O)NC4=CC=CC=C4)S (=O) (=O)[O-]. [Na+]. ECNumber: 233-365-1. Catalog: ACM10130297.
Hetrombopag
Hetrombopag is an orally active human thrombopoietin receptor agonist. Hetrombopag protects Cardiomyocyte Survival from Oxidative Stress Damage as an Enhancer of Stem Cells. Hetrombopag specifically stimulated proliferation and/or differentiation of human TPOR-expressing cells, including 32D-MPL and human hematopoietic stem cells, with low nanomolar EC50 values through stimulation of STAT, PI3K and ERK signalling pathways. Notably, hetrombopag effectively up-regulated G1 -phase-related proteins, including p-RB, Cyclin D1 and CDK4/6, normalized progression of the cell cycle, and prevented apoptosis by modulating BCL-XL/BAK expression in 32D-MPL cells. Group: Agonists. Alternative Names: SHR8735; SHR 8735; SHR-8735; Hetrombopag. CAS No. 1257792-41-8. Molecular formula: C25H22N4O5. Mole weight: 458.47. Appearance: Solid powder. Purity: >98%. IUPACName: (E)-5-(2-hydroxy-3-(2-(3-methyl-5-oxo-1-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)phenyl)furan-2-carboxylic acid. Canonical SMILES: O=C (C1=CC=C (C2=CC=CC (N/N=C3C (N (C4=CC=C5CCCCC5=C4) N=C/3C) =O) =C2O) O1) O. Catalog: ACM1257792418.
Sivifene gel is the phenylhydrazone 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone formulated as a topical agent with immunomodulating and potential antineoplastic activities. Applied topically as a gel, sivifene may stimulate a local immune response against human papillomavirus (HPV)-induced cervical intraepithelial neoplasia. Synonyms: A 007; A007; A-007; 4-[[2-(2,4-dinitrophenyl)hydrazinyl]-(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one; 4,4'-Dihydroxybenzophenone 2,4-dinitrophenylhydrazone. CAS No. 2675-35-6. Molecular formula: C19H14N4O6. Mole weight: 394.34.
SQ 29548
SQ 29548 is a potent and selective TP receptor antagonist. It inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 μM. Synonyms: SQ-29548; SQ29548; (Z)-7-[(1S,2R,3R,4R)-3-[[2-(phenylcarbamoyl)hydrazinyl]methyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid. Grades: ≥98%. CAS No. 98672-91-4. Molecular formula: C21H29N3O4. Mole weight: 387.5.
A negative allosteric modulator selective for NR2A containingnMDA receptors (pIC50 = 6.8 and <4.3uM for NR2A and NR2B, respectively). No effect on NR2B-containingnMDA receptors with concentrations less than 50 mM. Inhibition on NR2A containingnMDA receptors is glycine (or D-serine)-binding, but not glutamate-binding, dependent. Group: Biochemicals. Grades: Highly Purified. CAS No. 852918-02-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
(Z)-JIB-04
(Z)-JIB-04 is a Z-isomer of JIB-04, which is a small-molecule histone demethylase inhibitor with antitumor activity. JIB-04 selectively inhibits tumor growth via targeting various tumorigenic signaling pathways. Synonyms: 5-Chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine; JIB-04 Z-isomer. CAS No. 199596-24-2. Molecular formula: C17H13ClN4. Mole weight: 308.769.
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