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2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid is an intermediate useful in the synthesis of rac-3-Oxo Atorvastatin SodiumSalt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1391194-36-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C33H33FN2O5, Molecular Weight: 556.62. US Biological Life Sciences.
2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of rac-3-Oxo Atorvastatin SodiumSalt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 947262-20-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C37H41FN2O5, Molecular Weight: 612.73. US Biological Life Sciences.
2'-Deoxy-5-azacytidylyl-(3'?5')-2'-deoxy-guanosine is an DNA methylation inhibitor in vivo and was shown to effectively tolerated in tumor-free mouse and was found to be similarly effective in reducing tumor growth. Uses: Antineoplastic agents. Synonyms: Guadecitabine sodium;SGI-110; Guadecitabine sodium [USAN]; S110 sodiumsalt; SGI-110 sodiumsalt; sodium; [(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] phosphate; 0RB89YH367; 2'-Deoxy-5-azacytidylyl-(3'-->5')-2'-deoxy-guanosine SodiumSalt; Guanosine, 2'-deoxy-5-azacytidylyl-(3'-5')-2'-deoxy-, sodiumsalt (1:1); SGI 110; SGI-110 sodium; S-110 sodium;Guadecitabine sodium (JAN/USAN);2'-Deoxy-5-azacytidylyl-(3'?5')-2'-deoxy-guanosine SodiuMSalt; Guadecitabine sodium; SGI-110 sodium. CAS No. 929904-85-8. Molecular formula: C18H23N9NaO10P. Mole weight: 579.39.
3-Oxo Rosuvastatin SodiumSalt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 3-Oxo Rosuvastatin SodiuMSalt;-7-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)aMino]-5-pyriMidinyl]-5-hydroxy-3-oxo-. Grades: > 95%. CAS No. 1346606-28-7. Molecular formula: C22H25FN3O6S. Na. Mole weight: 501.51.
A synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: (3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid SodiumSalt. Grades: Highly Purified. CAS No. 94061-80-0. Pack Sizes: 1mg. Molecular Formula: C24H25FNNaO4, Molecular Weight: 433.45. US Biological Life Sciences.
Worldwide
(3S,5S)-Atorvastatin sodiumsalt
Atorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective against hypercholesterolemia and certain dyslipidemias. Synonyms: 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, monosodiumsalt; 3S,5S-Atorvastatin Sodium; sodium (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate. Grades: ≥98%. CAS No. 1428118-38-0. Molecular formula: C33H34FN2O5·Na. Mole weight: 580.6.
(3S,5S)-Rosuvastatin SodiumSalt
An impurity of Rosuvastatin salt.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: Rosuvastatin (3S,5S)-Isomer Sodium ;(3S, 5S)-Rosuvastatin Sodium ;Enantiomer of (3R,5R)-Rosuvastatin Sodium ;(3S,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid sodiumsalt. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
Acrylates copolymer
Acrylates copolymer is able to absorb skin secretions, thereby reducing skin shine and providing an improved skin surface for makeup application. Acrylates copolymer also imparts a pleasant feel to a cosmetic preparation and helps reduce any feeling of oiliness the product may have. It is incorporated into numerous types of cosmetic formulations including skin cleansers, oil control treatments, makeup, and loose and compressed powders. When used in conjunction with a variety of other ingredients, including glycerine, cyclomethicone, retinyl palmitate, and vegetable oils, acrylates copolymer prolongs the availability of these other ingredients to the skin through a form of time-release activity. It also helps counteract some negative properties when applied to the skin, or further enhance positive ones. For example, acrylates copolymer reduces the tackiness and greasiness of glycerine while prolonging its availability in the interstitial network of the skin. When present with retinyl palmitate, acrylates copolymer improves the stability of the formulation and increases its skin contact time. Synonyms: Acrylates copolymer; 2-Propenoic acid, 2-methyl-, polymer with ethyl 2-propenoate and methyl 2-methyl-2-propenoate; acrylic acid terpolymer, partial sodiumsalts; methyl methacrylate/ ethyl acrylate/ methacrylic acid pol.; Acrylic acid-acrylate polymer; polym. Grades: 98%. CAS No. 25133-97-5. Molecular formula: C14H22O6. Mole weight: 286.3209.
Allura Red AC
Allura Red AC is a food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries. Synonyms: Allura Red; Food Red No.40; 6-Hydroxy-5-[2-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl]-2-naphthalenesulfonic Acid SodiumSalt; 6-Hydroxy-5-[(6-methoxy-4-sulfo-m-tolyl)azo]-2-naphthalenesulfonic Acid DisodiumSalt; Allura Red 40; FDC Red 40 dye; Fancy Red; Food Red 17. Grades: >95%. CAS No. 25956-17-6. Molecular formula: C18H14N2Na2O8S2. Mole weight: 496.42.
Allura Red AC
Color additive in foods, drugs and cosmetics. It is used as a food dye and has the E number E129. The study found increased levels of hyperactivity and attention deficit hyperactivity disorder and lower IQs were observed in children consuming the chemicals. It is banned in Denmark, Belgium, France, Switzerland, Sweden. Group: Biochemicals. Alternative Names: 6-Hydroxy-5-[2-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl]-2-naphthalenesulfonic Acid SodiumSalt; 6-Hydroxy-5-[(6-methoxy-4-sulfo-m-tolyl)azo]-2-naphthalenesulfonic Acid DisodiumSalt; Allura Red 40; Allura Red; C.I. Food Red 17; E 129; FD&C Red No. 40; FDC Red 40; FDC Red 40 dye; Fancy Red; Food Red 17; Food Red No. 17; Food Red No. 40; Japan Food Red No. 40. Grades: Highly Purified. CAS No. 25956-17-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Ceftriaxone Sodium
Ceftriaxone Sodium is an antibiotic, a third-generation cephalosporin. It has broad-spectrum activity against Gram-positive bacteria and expanded Gram-negative coverage. lt is useful for the treatment of a number of bacterial infections, includeing ear infections, skin infections, urinary tract infections, pneumonia, gonorrhea, pelvic inflammatory disease, bone and joint infections, intra-abdominal infections, and meningitis and so on. It is used preoperatively to reduce the risk of postoperative infections. It inhibits bacterial cell wall synthesis by means of binding to the penicillin-binding proteins. It is a stimulator of EAAT2 expression with neuroprotective effects in both in ... stimulator of eaat2 expression with neuroprotective effects in both in vitro and in vivo models, which is based in part on its ability to inhibit neuronal cell death by glutamate excitotoxicity. Synonyms: 2,5,6-tetrahydro-2-methyl-5,6-dioxo-)(methoxyimino)acetyl)amino)-8-oxo-3-(((4-triazin-3-yl)thio)methyl)-,sodiumsalt,hydrate(2:4:7)(6r-(6-alpha,7-2;beta(z)))-; [6R-[6alpha, 7beta (Z)]]-7-[[ (2-Amino-4-thiazolyl) (methoxyimino)acetyl]amino]-8-oxo-3-[[ (1, 2, 5, 6-tetrahydro-2-methyl-5, 6-dioxo-1, 2, 4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4. 2. 0]oct-2-ene-2-carboxylic acid sodiumsalt. Grades: 98%. CAS No. 74578-69-1. Molecular formula: C18H16N8Na2O7S3. Mole weight: 598.54.
Cerivastatin SodiumSalt
A competitive inhibitor of HMG-CoA reductase. Uses: Hydroxymethylglutaryl-coa reductase inhibitors. Synonyms: (3R,5S,6E)-7-[4-(4-Fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-6-heptenoic Acid SodiumSalt; Rivastatin, Baycol, Lipobay. Grades: > 95%. CAS No. 143201-11-0. Molecular formula: C26H33FNO5.Na. Mole weight: 458.56 22.99.
CI 42755
Water blue is an organic sodiumsalt resulting from the formal condensation of NSC 56820 with 2 mol eq. of sodium hydroxide. Uses: It is used as a histological stain for collagen and in mallory's method for connective tissue. it has a role as a histological dye. Group: Acid dyes. Alternative Names: MARINE BLUE, NSC8677, ANILINE BLUE, WATER SOLUBLE, CID407402, ZINC04261931, 28631-66-5. CAS No. 28631-66-5. Molecular formula: C32H25N3O9S3.2Na. Mole weight: 737.73. Appearance: Dark reddish-brown or blue crystals. IUPACName: 4-[[4-(anilino)phenyl]-(4-phenyliminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. Canonical SMILES: CC1=CC (=CC (=C1N)S (=O) (=O)[O-])C (=C2C=CC (=NC3=CC=C (C=C3)S (=O) (=O)O)C=C2)C4=CC=C (C=C4)NC5=CC=C (C=C5)S (=O) (=O)[O-]. [Na+]. [Na+]. ECNumber: 249-113-9. Catalog: ACM28631665.
Clodronate disodium tetrahydrate
Clodronate is a non-nitrogenous bisphosphonate that can bind to bone to reduce the bone resorption. It is used as an anti-osteoporotic drug for the prevention of osteoporosis in post-menopausal women and men. Uses: The treatment of osteoporosis. Synonyms: (Dichloromethylene)bisphosphonic Acid DisodiumSalt Tetrahydrate; Sodium clodronate hydrate; Disodium [dichloro (phosphonato)methyl]phosphonic acid tetrahydrate. Grades: >98%. CAS No. 88416-50-6. Molecular formula: CH10Cl2Na2O10P2. Mole weight: 360.908.
An impurity of Lovastatin. Lovastatin is an HMG CoA reductase inhibitor used to treat high blood cholesterol. Synonyms: 3,5-Dihydroxy-7-(8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl)heptenoate Acid SodiumSalt; [1S-[1α(βS*, δS*), 2β, 6β, 8β, 8aα]]-1, 2, 6, 7, 8, 8a-hexahydro-β, δ, 8-trihydroxy-2, 6-dimethyl-1-naphthaleneheptanoic Acid MonosodiumSalt. Grades: > 95%. CAS No. 132294-94-1. Molecular formula: C19H29O5Na. Mole weight: 360.42.
Efaproxiral
synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. One use for efaproxiral is to increase the efficacy of certain chemotherapy drugs which have reduced efficacy against hypoxic tumours, and can thus be made more effective by increased offloading of oxygen into the tumour tissues. However, no benefit was seen for efaproxiral in phase III clinical trials. Synonyms: RSR13; RSR-13; RSR 13; Efaproxyn; NSC722758; (24 (35di methyl anilino) carbonyl methyl phenoxyl2 methyl proprionic acid sodiumsalt. CAS No. 131179-95-8. Molecular formula: C20H23NO4. Mole weight: 341.4.
Efaproxiral Sodium
Efaproxiral, a synthetic allosteric modi?er of hemoglobinoxygen binding af?nity, has been shown to bind reversibly to hemoglobin, stabilizing the deoxyhemoglobin tetramer conformation to reduce its af?nity for oxygen. Synonyms: Efaproxiral sodium; 170787-99-2; RSR13 SODIUM; Sodium 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoate; Efaproxiral (sodium); Efaproxiral sodium [USAN]; RSR-13 SODIUM; 3L83QP52XI; 170787-99-2 (sodium); Efaproxyn; Efaproxiral sodium (USAN); Sodium 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoate; Propanoic acid, 2-(4-(2-((3,5-dimethylphenyl)amino)-2-oxoethyl)phenoxy)-2-methyl-, monosodiumsalt; Efaproxiral Sodium. Grades: >98%. CAS No. 170787-99-2. Molecular formula: C20H23NO4.Na. Mole weight: 363.38.
Fluvastatin 3-Hydroxy-4,6-diene SodiumSalt
Fluvastatin 3-Hydroxy-4,6-diene SodiumSalt is a metabolite of Fluvastatin, a synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: 7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxy-4,6-Heptadienoic Acid SodiumSalt. Grades: Highly Purified. CAS No. 1207963-21-0. Pack Sizes: 5mg. Molecular Formula: C24H23FNNaO3. US Biological Life Sciences.
Worldwide
Fluvastatin, SodiumSalt
A synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid SodiumSalt; Fluindostatin; XU 62-320; Lescol; Lipaxan; Primexin. Grades: Highly Purified. CAS No. 93957-55-2. Pack Sizes: 100mg, 500mg, 1g, 5g. Molecular Formula: C24H25FNNaO4, Molecular Weight: 433.45. US Biological Life Sciences.
Worldwide
Loxoprofen Sodium
A non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase. Group: Biochemicals. Alternative Names: α -Methyl-4-[ (2-oxocyclopentyl) methyl]benzeneacetic Acid SodiumSalt; CS 600; Loxonin; Sodium 2- [4- [ (2-Oxocyclopentyl) methyl] phenyl] propionate; Sodium Loxoprofen. Grades: Highly Purified. CAS No. 80382-23-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Methotrexate disodium
Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia). Synonyms: Amethopterin Sodium; Methotrexate Lederle; Metoart; Metotrexato Lederle; Sodium Methotrexate; N-[4-[[ (2, 4-Diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-glutamic Acid DisodiumSalt; 4-amino-n(sup10)-methyl pteroyl glutamic acid disodiumsalt; amethopterin sodium. Grades: >98.0%. CAS No. 7413-34-5. Molecular formula: C20H20N8Na2O5. Mole weight: 498.40.
Mevastatin Hydroxy Acid SodiumSalt
An active carboxylate of Mevastatin. It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid SodiumSalt;[1S-[1α( βS*, δS*), 2α, 8 β(R*),8aα]]-1,2,6,7,8,8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid MonosodiumSalt; ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid MonosodiumSalt; ML 236B SodiumSalt. Grades: Highly Purified. CAS No. 99782-89-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
N1-MethylpseudoUridine-5'-Triphosphate Lithium
N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (methylpseudouridine-5-triphosphate-sodium-358101.html">B2706-358101) is in stock. Synonyms: 1-Methylpseudouridine-5'-Triphosphate lithium salt; N1-Methylpseudo-UTP tetralithium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-, lithium salt; 1-Methylpseudo-UTP tetralithium salt. Grades: ≥90% by AX-HPLC. Molecular formula: C10H13Li4N2O15P3. Mole weight: 521.89.
N1-MethylpseudoUridine-5'-Triphosphate Sodium
It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The product has passed the functionality test in transcription reaction. The solution is free of DNase and RNase contamination. Synonyms: 1-Methylpseudouridine-5'-Triphosphate sodiumsalt; N1-Methylpseudo-UTP sodiumsalt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-, sodiumsalt; 1-Methylpseudo-UTP sodiumsalt; 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP. Grades: 99%, 100mM sodiumsalt solution. Molecular formula: C10H17N2O15P3.xNa. Mole weight: 498.17 (free acid).
N-(Dithiocarboxy)-N-methyl-D-glucamine sodiumsalt
N-(Dithiocarboxy)-N-methyl-D-glucamine sodiumsalt is a compound used in biomedical research as a chelating agent for metal ions. It can also be used to stabilize certain enzymes and proteins. In pharmacology, it has been studied for its potential use in treating neurodegenerative diseases due to its ability to scavenge free radicals and reduce oxidative stress. Synonyms: N-(Dithiocarbamoyl)-N-methyl-D-glucamine sodiumsalt; Sodium N-Methyl-D-glucamine dithiocarbamate. CAS No. 91840-27-6. Molecular formula: C8H16NO5S2 Na. Mole weight: 293.34.
Pentosan polysulfate sodium
Pentosan polysulfate sodium is a biomedical product used for treating interstitial cystitis, a chronic bladder condition causing pain and frequent urination. This compound acts as an anticoagulant and a urinary protectant, reducing inflammation and restoring the integrity of the bladder lining. Synonyms: 4-O-Methyl-α-D-glucurono-β-D-xylan, hydrogen sulfate, sodiumsalt; Cartrophen; CB 8061; Elmiron; Fibrase; Fibrezym; Hemoclar; HOE/BAY 946; Pentosan polysulfate sodiumsalt; PPS; PZ 68; Sodium pentosan polysulfate; SP 54; Thrombocid. Grades: 95%. CAS No. 140207-93-8. Molecular formula: (C5H6Na2O10S2)n. Mole weight: 4000-6000.
Phosphonomycin Calcium salt
It is produced by the strain of Str. fradiae NRRL-3417, Str. viridchromogenes NRRL-3413. It's an antibiotic that contains phosphorus. It has anti-gram positive bacterial and negative bacterial activity, inorganic phosphorus and sodium chloride can reduce its activity. It has protective effect on mice infected with Staphylococcus aureus, Salmonella typhi and Salmonella paratyphi B by oral administration. Synonyms: (-)-Phosphonomycin Calcium salt; Calcium fosfomycin; fosfomycin calcium; Fosmicin; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (1:1); Phosphonic acid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)-; Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, calcium salt (1:1); Phosphonic acid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-cis)-. Grades: 98%. CAS No. 26016-98-8. Molecular formula: C3H5O4P.Ca. Mole weight: 176.12.
R788 disodium hexahydrate
R788 sodiumsalt hydrate, a methylene phosphate prodrug of the active metabolite R406, is a potent Syk inhibitor. It can be rapidly converted to R406 in vivo. It effectively inhibits BCR signaling in vivo, resulting in reduced proliferation and survival of the malignant B cells and significantly prolonged survival of the treated animals. Synonyms: Fostamatinib disodium hexahydrate; R788 disodium hexahydrate; R 788 disodium hexahydrate; R-788 disodium hexahydrate. Grades: >98%. CAS No. 914295-16-2. Molecular formula: C23H24FN6Na2O9P. Mole weight: 624.42.
Rosuvastatin-d6, SodiumSalt
Labelled Rosuvastatin, a selective, competitive HMG-CoA reductase inhibitor. Group: Biochemicals. Alternative Names: 7-[4- (4-Fluorophenyl)-6- (1-methylethyl-d6)-2-[methyl (methylsulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy-6-heptenoic Acid SodiumSalt. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C??H??D?FN?NaO?S, Molecular Weight: 509.56. US Biological Life Sciences.
Worldwide
Rosuvastatin Impurity 1 SodiumSalt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5S)-5-[(R)-8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl]-3,5-dihydroxypentanoic Acid SodiumSaltSynonyms: (β R, δ S, 6R) -8-Fluoro-5, 6-dihydro-β , δ -dihydroxy-4- (1-methylethyl) -2-[methyl (methylsulfonyl) amino]benzo[h]quinazoline-6-pentanoic Acid SodiumSalt. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
Rosuvastatin Impurity 2 SodiumSalt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5S)-5-[(S)-8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl]-3,5-dihydroxypentanoic Acid SodiumSaltSynonyms: (β R, δ S, 6S) -8-Fluoro-5, 6-dihydro-β , δ -dihydroxy-4- (1-methylethyl) -2-[methyl (methylsulfonyl) amino]benzo[h]quinazoline-6-pentanoic Acid SodiumSalt. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
Rosuvastatin SodiumSalt
Rosuvastatin SodiumSalt.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(N-methyl-N-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid sodiumsalt. Grades: > 95%. CAS No. 147098-18-8. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
Rosuvastatin SodiumSalt (Mixture of (3R,5R), (3S,5S), (3R,5S) and (3S,5R) Isomers)
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 1007871-86-4; Rosuvastatinsodium; Rosuvastatin (Sodium); Rosuvastatincalcium; ZD 4522 SodiumSalt; X-Plended SodiumSalt; Crestor SodiumSalt; AKOS015896415; AM84431; A24860; EN300-718737; rac-Rosuvastatin SodiumSalt (Mixture: R700515 and SodiumSalt of R700500); 7-{4- (4-fluorophenyl)-6-isopropyl-2-[methyl (methylsulfonyl)amino]pyrimidin-5-yl}-3, 5-dihydroxyhept-6-enoic acid; Sodium (E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate; sodium 7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate. Grades: > 95%. CAS No. 1007871-86-4. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
Salinomycin, SodiumSalt
Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodiumsalt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within HMLER breast cancer cells (IC50s = ~24 versus ~90uM).1 At 8uM, salinomycin treatment of 4T1 and MCF7Ras breast cancer cell lines results in a ~2-fold and ~3-fold, respective reduction of CSCs relative to controls.1 Treatment of 5mg/kg salinomycin in mice implanted with SUM159 human breast cancer cells inhibits mammary tumor growth and induces increased epithelial differentiation of tumor cells. Group: Biochemicals. Alternative Names: alpha-ethyl-6?[5-[2-(5-?ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,?10, 12-trimethyl-1, 6, 8-trioxadispiro[4. 1. 5. 3]pentadec-13-en-9-yl]-2-?hydroxy-1, ?3-dimethyl-4- oxoheptyl]tetrahydro-5-methyl-2H-pyran-2-acetic acid,? monosodiumsalt. Grades: Highly Purified. CAS No. 55721-31-8. Pack Sizes: 5mg, 10mg, 50mg. Molecular Formula: C42H69O11 Na, Molecular Weight: 773. US Biological Life Sciences.
Worldwide
Sulfobromophthalein Sodium (BSP)
Sulfobromophthalein disodiumsalt hydrate has been used as a positive control to study the interaction of 11-keto- β-boswellic acid (KBA) and 3-acetyl-11-keto- β-boswellic acid (AKBA) with organic anion transporter OATP1B3. Sulfobromophthalein (BSP) is a high affinity organic ion substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein 2 (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20. Group: Biochemicals. Alternative Names: Bromsulfalein disodiumsalt hydrate; Bromothalein disodiumsalt hydrate; Sulfobromophthalein disodiumsalt hydrate; BSP; disodium 2-hydroxy-5-1z-4-oxo-3-sulfonatocyclohexa-2,5-dien-1-ylidene 2,3,4,5-tetrabromo-6-carboxyphenyl methyl benzenesulfonate tetrahydrate. Grades: Highly Purified. CAS No. 123359-42-2. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C20H8Br4O10S2·2Na, Molecular Weight: 837.99. US Biological Life Sciences.
Worldwide
(3R,5R)-Rosuvastatin SodiumSalt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
(3S,5S)-Atorvastatin SodiumSalt
A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βS,δS)-2-(4-Fluorophenyl)- β , δ -dihydroxy-5- (1-methylethyl)-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium; 3S,5S-Atorvastatin Sodium. Grades: Highly Purified. CAS No. 501121-34-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C33H34FN2NaO5, Molecular Weight: 580.62. US Biological Life Sciences.
Worldwide
Hydroxy Cerivastatin-d3 SodiumSalt
A labeled metabolite of Cerivastatin, a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-[(1S)-2-hydroxy-1-methylethyl]-5-[(methoxy-d3)-methyl]-2-(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Methyl Orange, Indicator, SodiumSalt, 0.05% Aqueous, Laboratory Grade, 500 mL
Formula: C14H14N3O3SNa. Formula Wt: 327. 34. Characteristic: Orange/yellow. Notes: Indicator pH 3. 0 red to 4. 4 yellow. Storage Code: Green; general chemical storage. Group: chem-category ph-indicators. Grades: chem-grade laboratory. CAS No. 547-58-0. Product ID: 875435. -- SOLD FOR EDUCATIONAL USE ONLY --
Methyl Orange, Indicator, SodiumSalt, 0.1% Aqueous, Laboratory Grade, 30 mL
Formula: C14H14N3O3SNa. Formula Wt: 327. 34. Characteristic: Orange/yellow. Notes: Indicator pH 3. 0 red to 4. 4 yellow. Storage Code: Green; general chemical storage. Grades: chem-grade laboratory. CAS No. 547-58-0. Product ID: 875437. -- SOLD FOR EDUCATIONAL USE ONLY --
Methyl Orange, Indicator, SodiumSalt, Powder, Laboratory Grade, 25 g
Formula: C14H14N3O3SNa. Formula Wt: 327. 34. Characteristic: Orange/yellow. Notes: Indicator pH 3. 0 red to 4. 4 yellow. Storage Code: Blue; toxic. Group: chem-category ph-indicators. Grades: chem-grade laboratory. CAS No. 547-58-0. Product ID: 875408. -- SOLD FOR EDUCATIONAL USE ONLY --
MethylRed, Indicator, 0.2% in Alcohol, Laboratory Grade, 500 mL
Indicator pH 4. 4 red to 6. 2 yellow, sodiumsalt Formula: C15H14N3O2Na. Formula Wt: 291. 28. Storage Code: Red; flammable. Group: chem-category ph-indicators. Alternative Names: Acid red 2 sodiumsalt. Grades: chem-grade laboratory. CAS No. 845-10-3. Product ID: 875505. -- SOLD FOR EDUCATIONAL USE ONLY --
Rosuvastatin Impurity H SodiumSalt (Mixture of Diastereomers)
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5RS)-5-[8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl]-3,5-dihydroxypentanoicacid calcium salt. Grades: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
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