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4-Methylmorpholine. Group: Biochemicals. Alternative Names: 1-Methylmorpholine; 4-Methylmorpholine; KL 21; N-Methylmorpholine; NMM; NSC 938. Grades: Highly Purified. CAS No. 109-02-4. Pack Sizes: 100ml. Molecular Formula: C5H11NO, Molecular Weight: 101.15. US Biological Life Sciences.
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4-Methylmorpholine N-oxide
4-Methylmorpholine N-oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 7529-22-8. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C5H11NO2. US Biological Life Sciences.
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4-Methylmorpholine N-oxide
4-Methylmorpholine N-oxide. Synonyms: 4-methyl-morpholin4-oxide;Morpholine, 4-methyl-, 4-oxide;Morpholine,4-methyl-,4-oxide;N-Methylmorpholine oxide. CAS No. 7529-22-8. Product ID: CDC10-0464. Molecular formula: C5H11NO2. Category: Cosmetic Surfactants. Product Keywords: Cosmetic Ingredients; Cosmetic Surfactants; 4-Methylmorpholine N-oxide; CDC10-0464; 7529-22-8; C5H11NO2; 4-methyl-morpholin4-oxide; Morpholine, 4-methyl-, 4-oxide; Morpholine,4-methyl-,4-oxide; N-Methylmorpholine oxide; 231-391-8; MFCD00005947; 7529-22-8. Purity: 0.98. Color: Colourless to slightly yellow. EC Number: 231-391-8. Physical State: Liquid. Quality Level: 200. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4ºC). Store protected from moisture. Boiling Point: 118-119ºC. Melting Point: 180-184ºC. Density: 1.14 g/cm3. Product Description: 4-Methylmorpholine N-oxide is an organic compound used as a co-oxidant along with OsO4 and ruthenates in organic synthesis. In recent studies, it has been used as a catalyst in silylcyanation of aldehydes and ketones. Lyocell, a regenerated cellulose fiber, can be prepared using 4-methylmorpholine N-oxide in an eco-friendly manner.
4-Methylmorpholine N-oxide
4-Methylmorpholine N-oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-methyl-morpholin4-oxide;Morpholine, 4-methyl-, 4-oxide;Morpholine,4-methyl-,4-oxide;N-Methylmorpholine oxide;4-METHYLMORPHOLINE N-OXIDE;4-METHYLMORPHOLINE 4-OXIDE;N-METHYLMORPHOLINE 4-OXIDE;NMO. Product Category: Heterocyclic Organic Compound. CAS No. 7529-22-8. Molecular formula: C5H11NO2. Mole weight: 117.15. Density: 1,14 g/cm³. Product ID: ACM7529228. Alfa Chemistry ISO 9001:2015 Certified.
4-Methylmorpholine N-oxide monohydrate
4-Methylmorpholine N-oxide monohydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 70187-32-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C5H13NO3. US Biological Life Sciences.
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Borane 4-Methylmorpholine Complex
Borane 4-Methylmorpholine Complex is a reducing agent present in the synthesis of 3-O-sulfted red seaweed galactan-derived disaccharide alditol. Group: Biochemicals. Grades: Highly Purified. CAS No. 15648-16-5. Pack Sizes: 1g, 5g. Molecular Formula: C5H14BNO, Molecular Weight: 114.98. US Biological Life Sciences.
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N-Methylmorpholine
500g Pack Size. Group: Building Blocks, Organics, Solvents. Formula: O(C2H4)2NCH3. CAS No. 109-02-4. Prepack ID 75505312-500g. Molecular Weight 101.15. See USA prepack pricing.
N-Methylmorpholine 99+% (GC)
N-Methylmorpholine 99+% (GC). Group: Biochemicals. Grades: GC. CAS No. 109-02-4. Pack Sizes: 250ml, 1L, 2.5L, 4L, 16L. US Biological Life Sciences.
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N-Methylmorpholine N-Oxide
4-Methylmorpholine N-Oxide is a metabolite of Morpholine. N-Methylmorpholine N-Oxide is commonly used to dissolve cellulose as well as in the dissolution of of scleroproteins. Group: Biochemicals. Alternative Names: 4-Methylmorpholine 4-Oxide; 4-Methylmorpholine Oxide; 4-Methylmorpholine N-Oxide; N-Methylmorpholine Oxide; N-methylmorpholine N-Oxide; NMMO; NMO; NSC 73198; NSC 82153. Grades: Highly Purified. CAS No. 7529-22-8. Pack Sizes: 5g. US Biological Life Sciences.
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N-Methylmorpholine propylsulfonate inner salt
N-Methylmorpholine propylsulfonate inner salt. Group: Biochemicals. Alternative Names: NMM-PS. Grades: Highly Purified. Pack Sizes: 5g, 10g, 25g, 50g. US Biological Life Sciences.
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N-Methylmorpholine propylsulfonate inner salt 99+%
N-Methylmorpholine propylsulfonate inner salt 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 50g. US Biological Life Sciences.
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(R)-3-Methylmorpholine
(R)-3-Methylmorpholine. Group: Biochemicals. Grades: Highly Purified. CAS No. 74572-04-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H11NO. US Biological Life Sciences.
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2,2,6-Trifluoro-4-methyl-morpholine
2,2,6-Trifluoro-4-methyl-morpholine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MolPort-004-814-826, NSC361573, CID338517, 80958-33-4. Product Category: Heterocyclic Organic Compound. CAS No. 80958-33-4. Molecular formula: C5H8F3NO. Mole weight: 155.1183. Purity: 0.96. IUPACName: 2,2,6-trifluoro-4-methylmorpholine. Canonical SMILES: CN1CC(OC(C1)(F)F)F. Density: 1.26g/cm³. Product ID: ACM80958334. Alfa Chemistry ISO 9001:2015 Certified.
(4-Methylmorpholin-2-yl)methanamine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Morpholinemethanamine,4-methyl-(9CI);(4-METHYLMORPHOLIN-2-YL)METHANAMINE;4-Methyl-2-aminomethylmorpholine. Product Category: Heterocyclic Organic Compound. CAS No. 141814-57-5. Molecular formula: C6H14N2O. Mole weight: 130.19. Density: 0.976. Product ID: ACM141814575. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Cys(STmp)-OH
Fmoc-Cys(STmp)-OH is a novel new tool for the regioselective synthesis of multiple disulfide bridged peptides by Fmoc SPPS. The STmp group is stable to piperidine but is extremely easy to remove by mild thiolysis. Albericio has reported removing four STmp groups on the solid phase with only three 5 minute treatments of 0.1 M N-methylmorpholine (NMM) in DMF containing 5% DTT. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(STmp)-OH, N-α-Fmoc-S-2,4,6-trimethoxyphenylthio-L-cysteine. Product Category: Amino Acids. CAS No. 1403834-74-1. Molecular formula: C27H27NO7S2. Mole weight: 541.64. IUPACName: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2,4,6-trimethoxyphenyl)disulfanyl]propanoic acid. Canonical SMILES: COC1=CC(=C(C(=C1)OC)SSCC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)OC. Density: 1.4±0.1 g/cm3. Product ID: ACM1403834741. Alfa Chemistry ISO 9001:2015 Certified.
Lateritin
Lateritin is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor isolated from the mycelial cake of Gibberella lateritium; bassiatin is the (3S,6R) isomer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Lateritin; Bassiatin. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 65454-13-9. Molecular formula: C15H19NO3. Mole weight: 261.31. Purity: >98%. IUPACName: 3-benzyl-6-isopropyl-4-methylmorpholine-2,5-dione. Canonical SMILES: O=C(OC1C(C)C)C(CC2=CC=CC=C2)N(C)C1=O. Product ID: ACM65454139. Alfa Chemistry ISO 9001:2015 Certified. Categories: Laterite.
(S)-3-Methyl Morpholine
It is useful in preparation of morpholinopyrimidine derivatives as mTOR kinase inhibitors for the treatment of diseases mediated by mTOR kinase and/or one or more PI3K enzymes. Group: Biochemicals. Alternative Names: (3S)-3-Methylmorpholine. Grades: Highly Purified. CAS No. 350595-57-2. Pack Sizes: 250mg. US Biological Life Sciences.
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3- (2-Methylmorpholino) aniline
3- (2-Methylmorpholino) aniline. Group: Biochemicals. Alternative Names: 3-(2-Methyl-4-morpholinyl)-benzenamine; 3-(2-Methylmorpholin-4-yl)aniline. Grades: Highly Purified. CAS No. 1152587-85-3. Pack Sizes: 100mg. Molecular Formula: C11H16N2O, Molecular Weight: 192.26. US Biological Life Sciences.
4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, also known as DMTMM, is an alcohol and water-soluble coupling reagent used to synthesise amides and esters in a one-step procedure. DMTMM is selective, achieves good yields and can be easily removed under reduced pressure from the reaction mixture. DMTMM finds application in the activation of carboxyl polysaccharides to make glucans, in the functionalisation of poly(acrylic acid) and poly(methacrylic acid) with amines via amide bonds, to make glycoconjugates and for coupling propylamine and butylamine to hyaluronic acid. Group: Biochemicals. Alternative Names: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride; DMTMM; MMTM. Grades: Highly Purified. CAS No. 3945-69-5. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C??H??ClN?O?, Molecular Weight: 276.72. US Biological Life Sciences.
DMTMM, a conjugating agent that efficiently conjugat PnPS to Luminex microspheres without affecting the antigenicity of a broad set of PnPS. Synonyms: DMTMM; DMT-MM; kunishima coupling reagent; dmt-mm; Morpholinium, 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-, chloride; J-650384; 4-(4,6-dimethoxy-[1,3,5]triazin-2-yl)-4-methyl-morpholin-4-ium chloride; dmtmm chloride; ACMC-209j5l; SCHEMBL28467; CTK3J8302. Grades: ≥ 95%. CAS No. 3945-69-5. Molecular formula: C10H17ClN4O3. Mole weight: 276.72.
7'-O-(4,4'-Dimethoxytrityloxy)morpholinothymine
7'-O-(4,4'-Dimethoxytrityloxy)morpholinothymine is a crucial compound in biomedicine extensively used in the pharmaceutical industry. It exhibits potential as an antiviral drug against herpesviruses and is researched for its promising role in the treatment of various viral infections. Synonyms: 7'-O-(4,4'-dimethoxytrityl)-5-methylmorpholino uridine; 5'-O-(4,4'-dimethoxytrityl)morpholinothymidine; 1-[(2R,6S)-6-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]morpholin-2-yl]-5-methylpyrimidine-2,4-dione; (2R)-2beta-(5-Methyluracil-1-yl)-6beta-(4,4'-dimethoxytrityloxymethyl)morpholine. Grades: ≥95%. CAS No. 143485-05-6. Molecular formula: C31H33N3O6. Mole weight: 543.61.
ASTX-660 2HCl
The dihydrochloride salt form of ASTX-660 which is found to be an IAP as well as XIAP inhitor that could be significant in the studies of lymphoma and solid tumours. It is still under Phase I/II trial. Synonyms: ASTX660 2HCl; ASTX-660 2HCl; ASTX 660 2HCl; 1-(6-(4-fluorobenzyl)-3,3-dimethylindolin-1-yl)-2-((2R,5R)-5-methyl-2-(((R)-3-methylmorpholino)methyl)piperazin-1-yl)ethan-1-one dihydrochloride. Grades: 98%. CAS No. 1605316-16-2. Molecular formula: C30H43Cl2FN4O2. Mole weight: 581.59.
ASTX-660 Freebase
ASTX-660 is found to be an IAP as well as XIAP inhitor that could be significant in the studies of lymphoma and solid tumours. It is still under Phase I/II trial. Synonyms: ASTX660; ASTX-660; ASTX 660; 1-(6-(4-fluorobenzyl)-3,3-dimethylindolin-1-yl)-2-((2R,5R)-5-methyl-2-(((R)-3-methylmorpholino)methyl)piperazin-1-yl)ethan-1-one. Grades: 98%. CAS No. 1605584-14-2. Molecular formula: C30H41FN4O2. Mole weight: 508.59.
AZD-3147
AZD-3147 is an extremely potent and selective dual inhibitor of mTORC1 and mTORC2. It exhibits >300-fold selectivity for mTOR over PI 3-kinase isoforms. It has physicochemical and pharmacokinetic properties suitable for development as a potential clinical candidate. Uses: Azd-3147 has physicochemical and pharmacokinetic properties suitable for development as a potential clinical candidate. Synonyms: AZD3147; AZD-3147; AZD 3147; (S)-1-(4-(4-(1-(cyclopropylsulfonyl)cyclopropyl)-6-(3-methylmorpholino)pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea. Grades: >98%. CAS No. 1101810-02-9. Molecular formula: C24H31N5O4S2. Mole weight: 517.66.
AZD8055
A potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. It inhibits the phosphorylation of mTORC1 substrates p70S6K and 4E-BP1 as well as phosphorylation of the mTORC2 substrate AKT and downstream proteins. The rapamycin-resistant T37/46 phosphorylation sites on 4E-BP1 were fully inhibited by AZD8055, resulting in significant inhibition of cap-dependent translation. In vitro, AZD8055 potently inhibits proliferation and induces autophagy in H838 and A549 cells. In vivo, AZD8055 induces a dose-dependent pharmacodynamic effect on phosphorylated S6 and phosphorylated AKT at plasma concentrations leading to tumor growth inhibition. Group: Biochemicals. Alternative Names: 5- [2, 4-Bis [ (3S) -3-methyl-4-morpholinyl] pyrido [2, 3-d] pyrimidin-7-yl] -2-methoxy Benzene methanol; [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]- 2-methoxyphenyl] methanol; AZD 8055; [5- [2, 4-Bis ( (3S) -3-methylmorpholin-4-yl) pyrido [5, 6-e] pyrimidin-7-yl] -2-methoxyphenyl] methanol. Grades: Purified. CAS No. 1009298-09-2. Pack Sizes: 10mg. US Biological Life Sciences.
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BAY-1895344 hydrochloride
BAY-1895344 is a potent, orally available and highly selective ATR inhibitor (IC50= 7 nM), which potently inhibits proliferation of a broad spectrum of human tumor cell lines (median IC50 = 78 nM). In cellular mechanistic assays BAY 1895344 potently inhibited hydroxyurea-induced H2AX phosphorylation (IC50 = 36 nM). Synonyms: Elimusertib hydrochloride; BAY 1895344 hydrochloride; BAY1895344 hydrochloride; 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-3-yl)-1,7-naphthyridine hydrochloride; 2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine hydrochloride; Bay 1895344; 1,7-Naphthyridine, 2-[(3R)-3-methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-3-yl)-, hydrochloride (1:1). Grades: ≥95%. Molecular formula: C20H22ClN7O. Mole weight: 411.89.
BMS-247243
BMS-247243 is a novel β-Lactamase inhibitor which is a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Uses: Beta-lactamase-inhibitor. Synonyms: BMS-247243; BMS 247243; BMS247243; UNII-KG8365V22L. (6R,7R)-7-[[2-[4-[(E)-3-(carboxylatomethylamino)-3-oxoprop-1-enyl]-2,5-dichlorophenyl]sulfanylacetyl]amino]-3-[[2,6-dimethyl-1-[3-(4-methylmorpholin-4-ium-4-yl)propyl]pyridin-1-ium-4-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Grades: ≥98%. CAS No. 307316-55-8. Molecular formula: C36H41Cl2N5O8S3. Mole weight: 838.83.
CZ415
CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM; 2. inhibition of Akt (mTORC2 substrate) phosphorylation in HEK293T: IC50 = 14.8 nM; 3. inhibition of IFNγ release in stimulated human whole blood: IC50 = 226 nM. Synonyms: CZ415; CZ-415; CZ 415; (S)-1-(4-(7,7-dimethyl-4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea. CAS No. 1429639-50-8. Molecular formula: C22H29N5O4S. Mole weight: 459.57.
DMTMM
DMTMM (4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride. CAS No. 3945-69-5. Pack Sizes: 25 g; 100 g. Product ID: HY-Y1168.
N-Cyclohexyl-N'-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-methylbenzenesulfonicacid(1:1); 1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)-CARBO DIIMIDE ME; CMCT; N-CYCLOHEXYL-N-(2-MORPHOLINOETHYL)CARBO DIIMIDE-MTS; CMC METHO-P-TOLUENESULFONATE; 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluensulfonate; MORPHO CDI; cme-carbodiimide; N-Cyclohexyl-N-(β-[N-methylmorpholino]ethyl)carbodiimide p-toluenesulfonate; 3-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate; N-cyclohexyl-N-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate; CHM; N-cyclohexyl-N-(2-morpholinoethyl)carbodiimide methyl p-toluenesulfonate; 1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate; 4-(2-(Cyclohexanecarboximidamido)ethyl)-4-methylmorpholin-4-ium 4-methylbenzenesulfonate. Appearance: white to slightly yellow powder. CAS No. 2491-17-0. Molecular formula: C14H26N3O·C7H7O3S. Mole weight: 423.6. Purity: 96+%. IUPACName: N'-cyclohexyl-N-[2-(4-methylmorpholin-4-ium-4-yl)ethyl]methanediimine;4-methylbenzenesulfonate. Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)[O-].C[N+]1(CCOCC1)CCN=C=NC2CCCCC2. ECNumber: 219-650-3. Product ID: ACM2491170. Alfa Chemistry ISO 9001:2015 Certified.
PQR530
PQR530 is a potent dual pan PI3K/mTOR inhibitor undergoing phase II clinical trials in 2016. Aberrant activation of the PI3K/mTOR signaling pathway promotes the growth of malignant tumor cells. Study showed that PQR530 inhibited all PI3K isoforms and the mammalian target of rapamycin (mTOR) complexes C1/2 potently and selectively against tumor progression. Synonyms: PQR530; PQR0530; PQR 530. (S)-4-(difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine. Grades: ≥98%. CAS No. 1927857-61-1. Molecular formula: C18H23F2N7O2. Mole weight: 407.42.
SAR-405
SAR-405 is a potent and selective PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. SAR405 treatment also inhibits autophagy induced either by starvation or by MTOR (mechanistic target of rapamycin) inhibition. Combining SAR405 with everolimus results in a significant synergy on the reduction of cell proliferation using renal tumor cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SAR-405; SAR 405; SAR405. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1523406-39-4. Molecular formula: C19H21ClF3N5O2. Mole weight: 443.86. Purity: >98%. IUPACName: (S)-9-((5-chloropyridin-3-yl)methyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one. Canonical SMILES: O=C1C=C(N2[C@H](C)COCC2)N=C3N(CC4=CC(Cl)=CN=C4)[C@H](C(F)(F)F)CCN31. Product ID: ACM1523406394. Alfa Chemistry ISO 9001:2015 Certified. Categories: SR 405 (VA).
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