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| Product | Description | |
|---|---|---|
| 1-Methylpseudouridine | 1-Methylpseudouridine. Group: Biochemicals. Alternative Names: 1-Methyl-5-b-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 13860-38-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences. |  Worldwide |
| 1-MethylpseudoUridine | N1-methyl-pseudoUridine (1-Methylpseudouridine), a methylpseudoUridine, outperforms 5 mC and 5 mC/N1-methyl-pseudoUridine in translation. N1-methyl-pseudoUridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density. Synonyms: N1-Methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-b-D-ribofuranosyl-; (-)-1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; Antibiotic U-50228; U-50228; 1-N-Me-pseudouridine; (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol; Uracil, 1-methyl-5-b-D-ribofuranosyl-. Grades: ≥95%. CAS No. 13860-38-3. Molecular formula: C10H14N2O6. Mole weight: 258.23. |  |
| 1-MethylpseudoUridine-5'-triphosphate | 1-MethylpseudoUridine-5'-triphosphate is a vital reagent in biomedical research. It is commonly used as a substrate to study RNA modifications and their role in gene expression regulation. This modified nucleotide analog allows for the analysis of enzymatic activities, RNA synthesis, and translation processes. It finds applications in the study of RNA splicing, RNA folding, and RNA-protein interactions, aiding in the understanding and potential treatment of various diseases. | |
| 2'-O-Methylpseudouridine | 2'-O-Methylpseudouridine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. US Biological Life Sciences. | Worldwide |
| 2'-O-MethylpseudoUridine-5'-Triphosphate Lithium | 2'-O-MethylpseudoUridine-5'-Triphosphate Lithium is a nucleotide analog commonly used in molecular biology research to investigate RNA modification and translation. It has been shown to enhance ribosomal reading efficiency and suppress frameshifting during translation. It may also play a role in regulating immune function and has potential therapeutic applications in autoimmunity and inflammatory diseases. Synonyms: 2'-O-Methylpseudo-UTP tetralithium salt. Grades: ≥90% by AX-HPLC. Molecular formula: C10H13Li4N2O15P3. Mole weight: 521.89. | |
| 6-Methylpseudouridine | 6-Methylpseudouridine is a powerful and discerning antiviral compound, boasting remarkable efficacy in the research of notorious RNA viruses like the Zika virus and hepatitis C. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 6-methyl-5-β-D-ribofuranosyl-; 6-Methyl-5-beta-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 1613530-10-1. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| N1-Methyl-2'-O-MethylpseudoUridine-5'-Triphosphate Lithium | A modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. Synonyms: N1,2'-O-Dimethylpseudo-UTP tetralithium salt; N1-Methyl-2'-O-Methylpseudo-UTP tetralithium salt. Grades: ≥90% by AX-HPLC. Molecular formula: C11H15Li4N2O15P3. Mole weight: 535.92. | |
| N1-MethylpseudoUridine-5'-Triphosphate | N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stock. Synonyms: 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-; 1-Methylpseudo-UTP. Grades: ≥95%. CAS No. 1428903-59-6. Molecular formula: C10H17N2O15P3. Mole weight: 498.17. | |
| N1-MethylpseudoUridine-5'-Triphosphate Lithium | N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stock. Synonyms: 1-Methylpseudouridine-5'-Triphosphate lithium salt; N1-Methylpseudo-UTP tetralithium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-, lithium salt; 1-Methylpseudo-UTP tetralithium salt. Grades: ≥90% by AX-HPLC. Molecular formula: C10H13Li4N2O15P3. Mole weight: 521.89. | |
| N1-MethylpseudoUridine-5'-Triphosphate Sodium | It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The product has passed the functionality test in transcription reaction. The solution is free of DNase and RNase contamination. Synonyms: 1-Methylpseudouridine-5'-Triphosphate sodium salt; N1-Methylpseudo-UTP sodium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-1-methyl-, sodium salt; 1-Methylpseudo-UTP sodium salt; 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP. Grades: 99%, 100mM sodium salt solution. Molecular formula: C10H17N2O15P3.xNa. Mole weight: 498.17 (free acid). | |
| N3-MethylpseudoUridine | 3-MethylpseudoUridine is used for increasing viability or longevity of organ or organ explant using modified mRNAs for proteins essential for organ survival. Synonyms: 3-Methyl-5-(beta-D-ribofuranosyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 3-methyl-5-beta-D-ribofuranosyl-; 3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; NSC 363818; (1S)-1,4-Anhydro-1-(3-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-D-ribitol. Grades: ≥95%. CAS No. 81691-06-7. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| 5,6-Dihydro-5-azathymidine | 5,6-Dihydro-5-azathymidine is produced by the strain of Streptomyces platensis var. clarensis (NRRL-8035). It has anti-gram-positive bacteria, negative bacteria and DNA virus activities. The strain also produces pseudouridine and 1-methylpseudouridine. Synonyms: 1-(2-Deoxypentofuranosyl)-4-hydroxy-5-methyl-5,6-dihydro-1,3,5-triazin-2(1H)-one. CAS No. 57350-36-4. Molecular formula: C9H15N3O5. Mole weight: 245.23. | |
| 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine | 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine, an essential compound in the field of biomedical research, holds immense significance for studying RNA modifications. Its role as a powerful tool in unraveling the impact of modified nucleosides on RNA structure and function is undeniable. Furthermore, its potential therapeutic implications in combating RNA dysregulation-associated ailments, such as cancer and neurodegenerative disorders, make it a promising avenue worth exploring. Synonyms: 3'-O-tert-butyldimethylsilyl-5'-O-DMT-N1-methylpseudoUridine; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyl-N1-methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1-methyl-; 5'-O-(4,4'-dimethoxitrityl)-3'-O-(tert-butyldimethylsilyl)-1-N-methylpseudouridine; 5-[(2S,3S,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-1-methylpyrimidine-2,4-dione. Grades: ≥95%. CAS No. 875302-43-5. Molecular formula: C37H46N2O8Si. Mole weight: 674.86. | |
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