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MI 14 is a PI 4-K IIIβ inhibitor with IC50 value of 54 nM. It shows antiviral activity against single-stranded positive sense RNA viruses in HeLa cell-based assays. Synonyms: MI-14; MI 14; MI14; N-[2-[[6-Chloro-3-[3-[(dimethylamino)sulfonyl]phenyl]-2-methylimidazo[1,2-b]pyridazin-8-yl]amino]ethyl]acetamide. Grades: ≥98% by HPLC. CAS No. 1715934-43-2. Molecular formula: C19H23ClN6O3S. Mole weight: 450.94.
MI 14
MI 14 is a selective PI4KIIIβ inhibitor with IC 50 s of 54 nM, >100 μM, >100 μM for PI4KIIIβ, PI4KIIIα, PI4KIIα, respectively. MI 14 has antiviral activity against HCV 1b, CVB3, HRVM, HVC 2a [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1715934-43-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-110248.
Gold wire, 14kt, red, 1.63mm (0.064in) dia, Au 58.3% min
Gold wire, 14kt, red, 1.63mm (0.064in) dia, Au 58.3% min. Group: Alloys.
Gold wire, 14kt, yellow, 1.63mm (0.064in) dia, Au 58.3% min
Gold wire, 14kt, yellow, 1.63mm (0.064in) dia, Au 58.3% min. Group: Alloys.
Microtubule-Associated Protein (142-161) (human)
Synonyms: C-Terminal Fragment of Microtubule Associated Protein Tau; H-Ser-Pro-Gln-Leu-Ala-Thr-Leu-Ala-Asp-Glu-Val-Ser-Ala-Ser-Leu-Ala-Lys-Gln-Gly-Leu-OH; L-Seryl-L-prolyl-L-glutaminyl-L-leucyl-L-alanyl-L-threonyl-L-leucyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-valyl-L-seryl-L-alanyl-L-seryl-L-leucyl-L-alanyl-L-lysyl-L-glutaminylglycyl-L-leucine. Grades: ≥95%. CAS No. 565227-74-9. Molecular formula: C86H147N23O31. Mole weight: 1999.25.
Midasin (1471-1481)
Midasin (1471-1481) is amino acids 1471 to 1481 fragment of Midasin. Midasin is a member of the AAA(+) family of ATPases. It is a nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits. Synonyms: Dynein-related AAA-ATPase MDN1 (1471-1481). Grades: >98%.
Milori Blue 14038-43-8
Milori Blue - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Minocycline Impurity 14
Minocycline Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1035979-44-2. Molecular formula: C24H30ClN3O8. Mole weight: 523.96. Catalog: APB1035979442.
Mirabegron Impurity 14
Mirabegron Impurity 14 is an impurity in commercial preparation of Mirabegron. Synonyms: 3-[(4-{2-[(2-hydroxy-2- phenylethyl) amino]ethyl}phenyl) carbamoyl]propanethioic S- acid. Grades: > 95%. Molecular formula: C20H24N2O3S. Mole weight: 372.48.
An a 2-Adrenergic blocker. An analogue of Mianserin. Antidepressant. Group: Biochemicals. Alternative Names: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; Org-3770; Remeron; Zispin. Grades: Highly Purified. CAS No. 85650-52-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
An a 2-Adrenergic blocker. An analogue of Mianserin. Antidepressant. Group: Biochemicals. Alternative Names: 1,2,3,4,10,14b-Hexahydro-2-(methyl-d3)-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; Org-3770-d3; Remeron-d3; Zispin-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ostreogrycin A (Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, Antibiotic 14752-2, Antibiotic E129A, Antibiotic PA 114A, Antibiotic 1745Z3A, Antibiotic 547C, Factor M)
Ostreogrycin A also commonly referred to as virginiamycin M1 or streptogramin A is the major component of the "virginamycin complex". In the 1950s this complex was independently discovered so many times the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts syngeristically with the structurally unrelated cyclic depsipeptides more commonly known as the virginiamycins B (ostreogrycin B or streptogramin B) and S to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A has proven to be highly active against Gram positive bacteria, particularly methicillin-resistant S. aureus. Group: Biochemicals. Alternative Names: Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, Antibiotic 14752-2, Antibiotic E129A, Antibiotic PA 114A, Antibiotic 1745Z3A, Antibiotic 547C, Factor M. Grades: Highly Purified. CAS No. 21411-53-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
palmitoyl-CoA 14-(E/Z)-desaturase
The enzyme, found in the moth Ostrinia furnacalis (Asian corn borer), produces a mixture of (E)- and (Z)- isomers. The products are subsequently truncated by partial β-oxidation to a blend of 12(E/Z)-tetradec-12-enoyl-CoA, which are converted to the species-specific sex pheromones (E)- and (Z)-tetradec-12-enoyl acetates. Group: Enzymes. Enzyme Commission Number: EC 1.14.19.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0996; palmitoyl-CoA 14-(E/Z)-desaturase; EC 1.14.19.32. Cat No: EXWM-0996.
10-Oxo Mirtazapine (Mirtazapine Impurity F)
10-Oxo Mirtazapine (Mirtazapine Impurity F). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Mirtazapine USP Related Compound D, Mirtazapine RC D (USP), Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-10(2H)-one, 1,3,4,14b-tetrahydro-2-methyl-, 2-Methyl-1,2,3,4-tetrahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepin-10(14bH)-one, Mirtazapine USP RC D,Mirtazapine Imp. F (EP). CAS No. 191546-97-1. IUPAC Name: (14bRS)-2-Methyl-1,3,4,14b-tetrahydropyrazino[2,1-a]pyrido-[2,3-c][2]benzazepin-10(2H)-one. Molecular formula: C17H17N3O. Mole weight: 279.34. Catalog: APS191546971. SMILES: CN1CCN2C(C1)c3ccccc3C(=O)c4cccnc24. Format: Neat.
10-Oxo Mirtazapine (Mirtazapine Impurity F)
Mirtazapine. Group: Biochemicals. Alternative Names: 1,3,4,14b-Tetrahydro-2-methyl-. Grades: Highly Purified. CAS No. 191546-97-1. Pack Sizes: 10mg. US Biological Life Sciences.
(±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. Synonyms: (5Z,8Z,14Z)-11,12-Epoxy-5,8,14-icosatrienoic acid methyl ester; Methyl (5Z,8Z)-10-[3-[(Z)-oct-2-enyl]oxiran-2-yl]deca-5,8-dienoate. Grades: ≥98%. CAS No. 73799-06-1. Molecular formula: C21H34O3. Mole weight: 334.5.
1,1,3,3-Tetramethyl-1,3-Bis[2-(5-Norbornen-2-yl)Ethyl]Disiloxane, Mixture of Endo and Exo
1,1,3,3-Tetramethyl-1,3-Bis[2-(5-Norbornen-2-yl)Ethyl]Disiloxane, Mixture of Endo and Exo. Uses: This product is suitable for scientific research. Group: Saltself assembly and lithographyposs nanohybrid materials. CAS No. 198570-39-7. Pack Sizes: 5 mL in glass bottle. Product ID: 2-(2-bicyclo[2.2.1]hept-5-enyl)ethyl-[2-(2-bicyclo[2.2.1]hept-5-enyl)ethyl-dimethylsilyl]oxy-dimethylsilane. Molecular formula: 374.71. Mole weight: C22H38OSi2. C[Si] (C) (CCC1CC2CC1C=C2)O[Si] (C) (C)CCC3CC4CC3C=C4. 1S/C22H38OSi2/c1-24 (2, 11-9-21-15-17-5-7-19 (21)13-17)23-25 (3, 4)12-10-22-16-18-6-8-20 (22)14-18/h5-8, 17-22H, 9-16H2, 1-4H3. UWRFNCCYPBVADT-UHFFFAOYSA-N. ≥ 97%.
11beta-Hydroxyprogesterone
11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone also activates human mineralocorticoid receptor in COS-7 cells with anED50of 10 nM. Synonyms: (8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; 11OHP compound; Duralutin; Gesterol; Hy-Gestrone; Hylutin; Hyprogest; Pergestron; pregn-4-ene-11 beta-ol-3,20-dione; Pro-Depo; Prodrox; 11β-Hydroxyprogesterone. CAS No. 600-57-7. Molecular formula: C21H30O3. Mole weight: 330.46.
11(Z),14(Z),17(Z)-Eicosatrienoic acid
11(Z),14(Z),17(Z)-Eicosatrienoic acid is an unsaturated fatty acid that can maintain the continued replication of functional mitochondria in Saccharomyces cerevisiae (KD115) [1]. Uses: Scientific research. Group: Natural products. CAS No. 17046-59-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108398B.
1, 2, 3, 4-Cyclobutane tetracarboxylic Acid 1,2,3,4-Tetramethyl Ester is product from the formation of a mixture of maleic anhydride and hexamethylbenzene when exposed to ultraviolet irradiation. Group: Biochemicals. Grades: Highly Purified. CAS No. 14495-41-1. Pack Sizes: 50mg, 100mg. Molecular Formula: C12H16O8, Molecular Weight: 288.25. US Biological Life Sciences.
1,2,3,4-Tetrahydro-6-isoquinolin-6-ol Hydrobromide is a chemical reagent used in the organic synthesis. Used in the preparation of androgen receptor modulators (SARMs) as well as steroidmimetic and chimeric microtubule disruptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 59839-23-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H11NO HBr, Molecular Weight: 149.19. US Biological Life Sciences.
Worldwide
1,2,3,4-Tetrahydroisoquinolin-6-ol
1,2,3,4-Tetrahydroisoquinolin-6-ol is a chemical reagent used in the organic synthesis. Used in the preparation of androgen receptor modulators (SARMs) as well as steroidmimetic and chimeric microtubule disruptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 14446-24-3. Pack Sizes: 50mg, 250mg. Molecular Formula: C9H11NO, Molecular Weight: 149.19. US Biological Life Sciences.
1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene. Uses: Tpe-mb is an intermediate of aggregation-induced emission (aie) material used in the synthesis of blue mitochondrial dyes for bio-imaging. tpe-mb may be used in the preparation of aggregation induced emission (aie) probes for the fluorescence detection of mercury(II) and glutathione. Group: Bioelectronic materials organic light-emitting diode (oled) materials other materials. Alternative Names: Benzene, 1,1'-(1,2-diphenyl-1,2-ethenediyl)bis[4-(bromomethyl)-. CAS No. 1053241-67-0. Pack Sizes: 25 mg in glass insert. Product ID: 1-(bromomethyl)-4-[(E)-2-[4-(bromomethyl)phenyl]-1,2-diphenylethenyl]benzene. Molecular formula: 518.28. Mole weight: C28H22Br2. BrCC (C=C1)=CC=C1/C (C2=CC=CC=C2)=C (C3=CC=CC=C3)/C4=CC=C (CBr)C=C4. 1S/C28H22Br2/c29-19-21-11-15-25 (16-12-21)27 (23-7-3-1-4-8-23)28 (24-9-5-2-6-10-24)26-17-13-22 (20-30)14-18-26/h1-18H, 19-20H2/b28-27+, GHZTXESUSOBGAM-BYYHNAKLSA-N. GHZTXESUSOBGAM-BYYHNAKLSA-N. 95%.
1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene
1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene. Uses: Tpe-ome is a hydroxy-group protected aggregation-induced emission (aie) material used in the synthesis of blue mitochandrial dye. Group: Synthetic tools and reagents. Alternative Names: 1,1'-(1,2-diphenyl-1,2-ethenediyl)bis[4-methoxybenzene],1,2-Bis(p-methoxyphenyl)-1,2-diphenylethylene,TPE-OMe. CAS No. 68578-78-9. Pack Sizes: 1 g in glass bottle. Product ID: 1-methoxy-4-[2-(4-methoxyphenyl)-1,2-diphenylethenyl]benzene. Molecular formula: 392.5g/mol. Mole weight: C28H24O2. COC (C=C1)=CC=C1/C (C2=CC=CC=C2)=C (C3=CC=CC=C3)/C4=CC=C (OC)C=C4. 1S/C28H24O2/c1-29-25-17-13-23 (14-18-25)27 (21-9-5-3-6-10-21)28 (22-11-7-4-8-12-22)24-15-19-26 (30-2)20-16-24/h3-20H, 1-2H3/b28-27+. SJCRDTOTGDVNJD-BYYHNAKLSA-N.
Sodium [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(2-methoxyethoxycarbonylamino)ethyl phosphate N-(Carbonyl-methoxypolyethylenglycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, MPEG-2000-DSPE, Na-salt, DLPG sodium. Grades: 99%. CAS No. 147867-65-0. Product ID: 8-04974. Molecular formula: C45H87O11NPNa. Mole weight: 872.13. Purity: for use in micelles, liposomes, and other lipid-based drug carriers Soluble in Chloroform sparingly, Methanol sparingly Storage -20 °C.
1,2-Dimyristoyl-sn-glycero-3-PG (sodium salt)
1,2-Dimyristoyl-sn-glycero-3-PG (DMPG) is a phospholipid containing the saturated long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes. Synonyms: 1,2-Dimyristoyl-sn-glycero-3-PG (sodium salt); 1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt. Grades: ≥99%. CAS No. 200880-40-6. Molecular formula: C34H66O10PNa. Mole weight: 688.85.
1-(2-Methoxypropoxy)-2-propanol
1-(2-Methoxypropoxy)-2-propanol (Mixture of Diastereomers) was identified as a bio-toxic composition of leachate of landfills by means to establish understandings towards possible adverse effects on human health and ecosystem. Group: Biochemicals. Alternative Names: 1-(2-methoxypropoxy)propan-2-ol. Grades: Highly Purified. CAS No. 13429-07-7. Pack Sizes: 10mg. Molecular Formula: C?H??O?, Molecular Weight: 148.2. US Biological Life Sciences.
Worldwide
13,14-Anhydro-10-desacetyl Baccatin
13,14-Anhydro-10-desacetyl Baccatin is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: Docetaxel Impurity 24. CAS No. 1217248-58-2. Molecular formula: C29H34O9. Mole weight: 526.57.
13-{[(3-N-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(triethylsilyl) Baccatin III
13-{[(3-N-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(triethylsilyl) Baccatin III is one of Paclitaxel precursors. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester; 5-{(3xi,5beta,7alpha,10beta,13alpha)-4,10-Bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-9-oxo-7-[(triethylsilyl)oxy]-5,20-epoxytax-11-en-13-yl} 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate. Grades: 98%. CAS No. 143527-71-3. Molecular formula: C54H73NO15Si. Mole weight: 1004.24.
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III is one of Paclitaxel precursors. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[[(2, 2, 2-trichloroethoxy)carbonyl]oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester; 5-[(3xi,5beta,7beta,10beta,13alpha)-4,10-Bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-9-oxo-7-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-5,20-epoxytax-11-en-13-yl] 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate. Grades: > 98%. CAS No. 143527-73-5. Molecular formula: C51H60Cl3NO17. Mole weight: 1065.38.
1,3,4,6-Tetra-O-acetyl-2-deoxy-2-iodo-b-D-galactopyranose, a coveted compound in organic synthesis, boasts a prowess of incorporating iodine atoms into carbohydrate molecules, rendering it an instrument of choice in the chemical manipulation of oligosaccharides. With its extensive use in producing glycosyl donors and acceptors, as well as its wide applicability as a precursor for iodinated carbohydrates, there is no denying the indispensability of this compound in the realm of carbohydrate chemistry. Synonyms: 1,3,4,6-TETRA-O-ACETYL-2-DEOXY-2-IODO-B-D-GALACTOPYRANOSE; 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-iodo-beta-D-galactopyranose; [(2R,3S,4S,5R,6S)-3,4,6-triacetyloxy-5-iodooxan-2-yl]methyl acetate; 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-iodo-beta-D-galactopyranose, Min. 98%. CAS No. 141510-66-9. Molecular formula: C14H19IO9. Mole weight: 458.20.
1, 3-Bis (methoxymethoxy) -5-[ (1E) -2-[4- (methoxymethoxy) phenyl]ethenyl]-benzene is a useful synthetic intermediate in the synthesis of Resveratrol Impurity B (H950990); an impurity of Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1 and also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. CAS No. 1414361-09-3. Pack Sizes: 1g, 10g. Molecular Formula: C20H24O6, Molecular Weight: 360.4. US Biological Life Sciences.
Worldwide
1,3-Cyclohexanebis(methylamine), mixture of isomers
1,3-Dibenzylurea is used in microwave assisted synthesis, molecular docking and HIV-1 gp 120 CD4 binding inhibition studies of symmetrical N,N-disubstituted urea/thiourea. Group: Biochemicals. Grades: Highly Purified. CAS No. 1466-67-7. Pack Sizes: 500mg, 1g. Molecular Formula: C15H16N2O. US Biological Life Sciences.
Worldwide
1,3-O-Dibenzyl-N-acetyl-β-D-glucosamine
Used in preparation of fluorinated glucosamine analogs which could inhibit cell migration and inflammation. Synonyms: Phenylmethyl 2-(Acetylamino)-2-deoxy-3-O-(phenylmethyl)-β-D-glucopyranoside. CAS No. 14855-31-3. Molecular formula: C22H27NO6. Mole weight: 401.45.
1400W Dihydrochloride
1400W dihydrochloride is the dihydrochloride form of 1400W (HY-18730). 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase ( iNOS ) inhibitor, with a K d value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 214358-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18731.
(±)14,15-Epoxyeicosatrienoic acid
(±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) is the Cytochrome P450 metabolite of arachidonic acid. While CYP3A4 may be involved in breast cancer cell growth, (±)14,15-Epoxyeicosatrienoic acid may promote mitosis and anchorage-dependent cloning through STAT3 affected by CYP3A4. (±)14,15-Epoxyeicosatrienoic acid exhibits STAT3-dependent cell growth promotion and may also participate in the autocrine/paracrine pathway that drives cell growth [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)14(15)-EET. CAS No. 197508-62-6. Pack Sizes: 50 μg (312.04 μM * 500 μL in Ethanol). Product ID: HY-150084.
1,4-Bis(aminomethyl)cyclohexane (cis- and trans- mixture)
14-epi-Hydroxymutilin is a derivative of Mutilin (M820050). Mutilin, is used to perform biological studies with focus on anti-microbial activity. This complex is also a reagent in the production of pleuromutilin derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 87680-55-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C20H32O3, Molecular Weight: 320.47. US Biological Life Sciences.
Worldwide
14-Methylpentadecanoic Acid
14-Methylpentadecanoic Acid is a fatty acid found in the soft tissues of the Far-?East bivalve mollusk Spisula sachalinensis. It is also a lipid biomarkers for microbial communities in hydrothermal chimney structures. Group: Biochemicals. Grades: Highly Purified. CAS No. 4669-2-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C16H32O2, Molecular Weight: 256.42. US Biological Life Sciences.
1-(5-Carboxypentyl)-2,3,3-trimethyl-3H-indol-1-ium-5-sulfonate, a highly sought-after fluorescent probe, has gained immense popularity in biomedical research due to its ability to detect minute cellular anomalies associated with cancer and other life-threatening diseases. Its application extends beyond its diagnostic potential and is frequently utilized in drug discovery initiatives aimed at identifying novel therapeutics that target specific and often elusive signaling pathways involved in disease progression. Its remarkable attributes and versatility have made it an indispensable tool in the ever-expanding realm of medical research. Synonyms: 1-(5-carboxypentyl)-2,3,3-trimethyl-3H-indolium-5-sulfonate (IM OCS). CAS No. 146368-08-3. Molecular formula: C17H23NO5S. Mole weight: 353.4.
15-keto-17-phenyl trinor prostaglandin F2α
15-keto-17-phenyl-13,14-dihydro trinor PGF2α isopropyl ester is a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Synonyms: 15-keto-17-phenyl trinor PGF2α; (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 949564-89-0. Molecular formula: C23H30O5. Mole weight: 386.5.
15(S)-HPETE
15(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A41 or reduced to 15(S)-HETE by peroxidases.2,1 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.3 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO. Uses: Scientific research. Group: Signaling pathways. CAS No. 70981-96-3. Pack Sizes: 25 μg (297.20 μM * 250 μL in Ethanol). Product ID: HY-113438.
1,6-Hexanediol Diacrylate
1,6-hexanediol diacrylate is a clear yellow liquid. (NTP, 1992);Liquid;Clear yellow liquid with a mild ester-like odor. Group: Polymers. Product ID: 6-prop-2-enoyloxyhexyl prop-2-enoate. Molecular formula: 226.27g/mol. Mole weight: C12H18O4. C=CC(=O)OCCCCCCOC(=O)C=C. InChI=1S/C12H18O4/c1-3-11 (13)15-9-7-5-6-8-10-16-12 (14)4-2/h3-4H, 1-2, 5-10H2. FIHBHSQYSYVZQE-UHFFFAOYSA-N.
16(R)-HETE
16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Synonyms: 16R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; (5Z,8Z,11Z,14Z)-(16R)-16-Hydroxyeicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-22-0. Molecular formula: C20H32O3. Mole weight: 320.5.
16(S)-HETE
16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. Synonyms: (16S)-hydroxyarachidonic acid; (5Z,8Z,11Z,14Z,16S)-16-hydroxyicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-23-1. Molecular formula: C20H32O3. Mole weight: 320.5.
17-AAG hydrochloride
17-AAG hydrochloride is a potent HSP90 inhibitor with IC50 value of 5 nM, which is a 100-fold higher binding affinity for HSP90 derived from tumour cells than that from normal cells. It is less toxic by binding to Hsp90 and altering its function. It causes the degradation of HER2, HER3, Akt, and both mutant and wild-type androgen receptor (AR), leading to the RB-dependent G1 growth arrest of prostate cancer cells. It has the ability to induce apoptosis of cells transformed with imatinib mesylate-resistant T315I and E255K BCR-ABL mutants with IC50 values of 2.3 μM and 1.0 μM, respectively. It displays significantly higher binding affinity for Hsp90 from 3T3-src, B16 or CT26 xenografts in nude mice compared with that from the normal tissues in vivo. Uses: 17-aag hydrochloride has the ability to induce apoptosis of cells transformed with imatinib mesylate-resistant t315i and e255k bcr-abl mutants. Synonyms: 17-AAG hydrochloride; 17 AAG hydrochloride; 17AAG hydrochloride; [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate hydrochloride;Tanespimycin Hydrochloride;NSC 330507 Hydrochloride;CP 127374 Hydrochloride;17-(Allylamino)-17-desmethylgeldanamycin hydrochloride. Grades: >98%. CAS No. 911710-03-7. Molecular formula: C31H44ClN3O8. Mole weight: 622.15.
17α-Hydroxymethyl-17 β-methyl-18-nor-2-oxa-5α-androst-13-en-3-one is a derivative of epiandrosterone (E578000), which is a steroid hormone that is present in normal human urine as a minor constituent , it is a less active 3 β-isomer of the androgen Androsterone (A635535). Group: Biochemicals. Grades: Highly Purified. CAS No. 1448460-32-9. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C19H28O3, Molecular Weight: 304.42. US Biological Life Sciences.
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17α-Hydroxyprogesterone Caproate
17α-Hydroxyprogesterone Caproate , a synthetic steroidal progestin, is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid used in the treatment of threatened miscarriage, gynecological disorders such as dysmenorrhea, premenstrual synd. Uses: More recently has received the most attention in the prevention of preterm birth. Synonyms: Primolut Depot; HYDROXYPROGESTERONE CAPROATE; [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate. Grades: ≥98%. CAS No. 630-56-8. Molecular formula: C27H40O4. Mole weight: 428.6.
17-Phenyl trinor prostaglandin E2 ethyl amide
17-Phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively). Synonyms: 17-phenyl trinor PGE2 ethyl amide; (Z)-N-ethyl-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide. Grades: ≥98%. CAS No. 1219032-20-8. Molecular formula: C25H35NO4. Mole weight: 413.6.
1-Bromododecane
Liquid. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Solubility enhancing reagents. Alternative Names: Lauryl bromide. CAS No. 143-15-7. Product ID: 1-bromododecane. Molecular formula: 249.23. Mole weight: C12H25Br. CCCCCCCCCCCCBr. InChI=1S / C12H25Br / c1-2-3-4-5-6-7-8-9-10-11-12-13 / h2-12H2, 1H3. PBLNBZIONSLZBU-UHFFFAOYSA-N. 98% min.
1-Bromotetradecane
1-Bromotetradecane. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Solubility enhancing reagents. CAS No. 112-71-0. Product ID: 1-bromotetradecane. Molecular formula: 277.29. Mole weight: C14H29Br. CCCCCCCCCCCCCCBr. InChI=1S / C14H29Br / c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15 / h2-14H2, 1H3. KOFZTCSTGIWCQG-UHFFFAOYSA-N. 98% min.
1-Bromovinylboronic acid MIDA ester
1-Bromovinylboronic acid MIDA ester. Group: Salt. CAS No. 1449377-16-5.
1-Decyl-3-methylimidazolium Tetrafluoroborate
1-Decyl-3-methylimidazolium tetrafluoroborate is an ionic liquid, which can be used as a clathrate hydrate crystal inhibitor in drilling fluid.It can also be used as a microextraction solvent in the determination of synthetic dyes in foods and cosmetics. Uses: Metal plating, electropolishing, metal reprocessing, phase transfer media, batteries fuel cells, nanomaterials, industrial solvents, nuclear fuel red waste, enzymatic catalysis, lubricants heat transfer and solar energy conversion. Group: Electrolytesbattery materials. Alternative Names: [C10MIM][BF4]. CAS No. 244193-56-4. Product ID: 1-decyl-3-methylimidazol-3-ium; tetrafluoroborate. Molecular formula: 310.19. Mole weight: C14H27BF4N2. [B-](F)(F)(F)F. CCCCCCCCCCN1C=C[N+](=C1)C. 1S / C14H27N2. BF4 / c1-3-4-5-6-7-8-9-10-11-16-13-12-15 (2) 14-16; 2-1 (3, 4) 5 / h12-14H, 3-11H2, 1-2H3; / q+1; -1. QGUMDWFYJYXDTH-UHFFFAOYSA-N. >98.0%(HPLC)(N).
1H,1H-Heptafluorobutyl acetate
1H,1H-Heptafluorobutyl acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1H,1H-HEPTAFLUOROBUTYL ACETATE;2,2,3,3,4,4,4-Heptafluorobutylacetate;1H,1H-HEPTAFLUOROBUTYL ACETATE, 97% MIN. Product Category: Heterocyclic Organic Compound. CAS No. 356-06-9. Molecular formula: C6H5F7O2. Mole weight: 242.09. Purity: 0.96. IUPACName: 2,2,3,3,4,4,4-heptafluorobutyl acetate. Canonical SMILES: CC(=O)OCC(C(C(F)(F)F)(F)F)(F)F. Density: 1435. Product ID: ACM356069. Alfa Chemistry ISO 9001:2015 Certified.
1-Hydroxycarvedilol
1-Hydroxy Carvedilol is a metabolite of Carvedilol found in humans, rats, dogs and mice. 1-Hydroxy Carvedilol is a β androneceptor antagonist with antioxidant and free radical scavenger activity. Synonyms: 4-[2-Hydroxy-3-[[2-(2-methoxyphenoxy)ethyl]amino]propoxy]-9H-carbazol-1-ol; BM 910183; SB 209995. Grades: > 95%. CAS No. 146574-41-6. Molecular formula: C24H26N2O5. Mole weight: 422.49.
1-Hydroxy Carvedilol
1-Hydroxy Carvedilol is a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice. 1-Hydroxy Carvedilol is a β androneceptor antagonist with antioxidant and free radical scavenger activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 146574-41-6. Pack Sizes: 5mg, 50mg. Molecular Formula: C24H26N2O5, Molecular Weight: 422.47. US Biological Life Sciences.
Worldwide
1-Methylcyclopentanol
1-Methylcyclopentanol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Methylcyclopentanol, Cyclopentanol, 1-methyl-, 1-Methyl-1-cyclopentanol, 1-Hydroxy-1-methylcyclopentane, ghl.PD_Mitscher_leg0.419, M39652_ALDRICH, NSC23230, CID73830, EINECS 215-963-4, ZINC01602491, 1462-03-9, InChI=1/C6H12O/c1-6(7)4-2-3-5-6/h7H,2-5H2,1H, UNL. Product Category: Alcohols. Appearance: white crystalline low melting solid. CAS No. 1462-03-9. Molecular formula: C6H12O. Mole weight: 100.16. Purity: 0.97. IUPACName: 1-methylcyclopentan-1-ol. Canonical SMILES: CC1(CCCC1)O. Density: 0.904. ECNumber: 215-963-4. Product ID: ACM1462039. Alfa Chemistry ISO 9001:2015 Certified.
1-O-Benzyl-2,3-O-isopropylidene-6-O-tosyl-a-L-sorbofuranoside is a compound that exhibits vast potential for therapeutic interventions in numerous pathophysiological conditions, such as neoplastic disorders and microbial infections. By exerting its anti-cancer and antibacterial effects through the perturbation of DNA replication processes, this compound has demonstrated significant efficacy in preclinical studies. Interestingly, its use as an adjunctive agent has also been explored with promising findings in enhancing the therapeutic outcomes of conventional drugs and in facilitating the development of novel treatment modalities. Synonyms: 1-O-BENZYL-2,3-O-ISOPROPYLIDENE-6-O-TOSYL-A-L-SORBOFURANOSIDE; 1-O-Benzyl-2,3-O-isopropylidene-6-O-tosyl-alpha-L-sorbofuranose; {(3aS,5S,6R,6aS)-3a-[(Benzyloxy)methyl]-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl}methyl 4-methylbenzenesulfonate. CAS No. 1459288-93-7. Molecular formula: C23H28O8S. Mole weight: 464.53.
1-Octanethiol
1-octanethiol appears as a clear colorless liquid. Flash point 115°F. Insoluble in water and less dense than water. Used to make other chemicals.;Liquid;COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.;Water-white liquid with a mild odor. Group: Self-assembly materials solubility enhancing reagents self assembly and contact printing materials. CAS No. 111-88-6. Product ID: octane-1-thiol. Molecular formula: 146.3g/mol. Mole weight: C8H18S;CH2SH(CH2)6CH3;C8H18S. CCCCCCCCS. InChI=1S / C8H18S / c1-2-3-4-5-6-7-8-9 / h9H, 2-8H2, 1H3. KZCOBXFFBQJQHH-UHFFFAOYSA-N.
1-Oxo Mirtazapine (Mirtazapine Impurity C)
1-Oxo Mirtazapine (Mirtazapine Impurity C). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-1(2H)-one, 3,4,10,14b-tetrahydro-2-methyl-, Mirtazapine Related Compound C (USP). CAS No. 191546-96-0. Molecular formula: C17H17N3O. Mole weight: 279.34. Catalog: APS191546960. SMILES: CN1CCN2C(C1=O)c3ccccc3Cc4cccnc24. Format: Neat.
1-Oxo Mirtazapine (Mirtazapine Impurity C)
Mirtazapine Impurity C. Group: Biochemicals. Alternative Names: 3,4,10,14b-Tetrahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-1(2H)-one;Mirtazapine Impurity C. Grades: Highly Purified. CAS No. 191546-96-0. Pack Sizes: 1mg. US Biological Life Sciences.
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