Monoacylglycer Suppliers USA
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Product | Description | |
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1H-Pyrrolo[3,2-b]pyridine-6-carboxylic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic Acid Methyl Ester is the methyl ester derivative of 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic Acid (P998590) and is used as a reagent in the synthesis of azetidinylpiperidine derivatives as monoacylglycerol lipase inhibitors useful in the treatment of inflammatory pain. Group: Biochemicals. Grades: Highly Purified. CAS No. 1015609-11-6. Pack Sizes: 50mg, 500mg. Molecular Formula: C9H8N2O2, Molecular Weight: 176.17. US Biological Life Sciences. | Worldwide |
2-Amino-1-(4-phenoxyphenyl)ethanol Quick inquiry Where to buy Suppliers range | 2-Amino-1-(4-phenoxyphenyl)ethanol is used as a reagent in the synthesis of (4-phenoxyphenyl) tetrazolecarboxamides and its related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). Group: Biochemicals. Grades: Highly Purified. CAS No. 153285-74-6. Pack Sizes: 100mg, 1g. Molecular Formula: C14H15NO2, Molecular Weight: 229.27. US Biological Life Sciences. | Worldwide |
(2E,?4E)?-2,?4-?Tetradecadienoic acid Quick inquiry Where to buy Suppliers range | (2E,?4E)?-2,?4-?Tetradecadienoic acid is used as a reactant in polymerization reactions such as the syntheses of monoacylglycerol and 1,?2-?diacyl-?sn-?glycerol. Group: Biochemicals. Grades: Highly Purified. CAS No. 24738-49-6. Pack Sizes: 5mg, 25mg. Molecular Formula: C14H24O2, Molecular Weight: 224.34. US Biological Life Sciences. | Worldwide |
2-Oleoyl glycerol Quick inquiry Where to buy Suppliers range | 2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol, is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases. Synonyms: 2-Monoolein; 2-OG; 2-Monooleoylglycerol; 2-Glyceryl monooleate; Glyceryl 2-oleate; 2-(9Z-octadecenoyl)-sn-glycerol. Grades: >99%. CAS No. 3443-84-3. Molecular formula: C21H40O4. Mole weight: 356.54. | |
ABX-1431 Quick inquiry Where to buy Suppliers range | ABX-1431 is an inhibitor of monoacylglycerol lipase (MAGL; IC50s = 14 and 27 nM for human and rat enzyme, respectively). Synonyms: 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[[2-pyrrolidin-1-yl-4- (trifluoromethyl) phenyl]methyl]piperazine-1-carboxylate. Grades: ≥98%. CAS No. 1446817-84-0. Molecular formula: C20H22F9N3O2. Mole weight: 507.3. | |
di-22:6-BMP Quick inquiry Where to buy Suppliers range | di-22:6-BMP can be used as a biomarker of tissue DIPL that can be monitored in the plasma/serum and urine. Synonyms: Di-22:6-Bis(monoacylglycerol)Phosphate; 1,1'-[Phosphinicobis[oxy[2-hydroxy-3,1-propanediyl]]] di-(4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-docosahexaenoate; 4,7,10,13,16,19-Docosahexaenoic acid, phosphinicobis[oxy[2-hydroxy-3,1-propanediyl]] ester, (4Z, 4'Z, 7Z, 7'Z, 10Z, 10'Z, 13Z, 13'Z, 16Z, 16'Z, 19Z, 19'Z)-. Molecular formula: C50H75O10P. Mole weight: 867.10. | |
FAAH Inhibitor III, URB937 (Cyclohexylcarbamic acid-(3-carbamoyl-6-hydroxybiphenyl-3-yl)ester, Fatty Acid Amide Hydrolase Inhibitor III, URB937, Cyclohexylcarbamic acid-carbamoyl hydroxybiphenyl-3-yl) ester) Quick inquiry Where to buy Suppliers range | A blood-brain-barrier impermeable p-hydroxyphenylcarbamate compound that acts as a potent and irreversible inhibitor of FAAH activity (IC50 = 26.8nM rat brain) with excellent selectivity over monoacylglycerol lipases (IC50 > 100uM). Shown to rapidly block mouse liver FAAH activity over brain (ED50 = 0.2mg/kg vs. 40mg/kg, s.c.), elevate anandamide and palmitoylethanolamide levels in peripheral tissues (1mg/kg, i.p.) and exert antinociceptive action. The CNS-penetrant FAAH Inhibitor II, URB597 is also available. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Glyceryl Monostearate Quick inquiry Where to buy Suppliers range | While the names glyceryl monostearate and mono- and diglycerides are used for a variety of esters of long-chain fatty acids, the esters fall into two distinct grades: 40-55 percent monoglycerides The PhEur describes glyceryl monostearate 40-55 as a mixture of monoacylglycerols, mostly monostearoylglycerol, together with quantities of di- and triacylglycerols. It contains 40-55% of monoacylglycerols, 30-45% of diacylglycerols, and 5-15% of triacylglycerols. Uses: Used for research and manufacturing. Group: Emulsifier Excipients. Alternative Names: Capmul GMS-50; Cutina GMS; 2, 3-dihydroxypropyl octadecanoate; Geleol; glycerine monostearate; glycerin monostearate; glycerol monostearate; glyceroli monostearas; glycerol stearate; glyceryl stearate; GMS; HallStar GMS; Imwitor 191; Imwitor 900; Kessco GMS; Lipo GMS; monoester with 1, 2, 3-propanetriol; monostearin; Myvaplex 600P; Myvatex; 1, 2, 3-propanetriol octadecanoate; Protachem GMS-450; Rita GMS; stearic acid, monoester with glycerol; stearic monoglyceride; Stepan GMS; Tegin; Tegin 503; Tegin 515; Tegin 4100; Tegin M; Unimate GMS. Grades: Pharmceutical Excipients. CAS No. 31566-31-1. Product ID: PE-0518. | |
Glycidyl Docosahexaenoate-d5 Quick inquiry Where to buy Suppliers range | A labeled monoacylglycerol used in the preparation of triacylglycerols acylated with n-3 polyunsaturated fatty acids for nutritional applications. Group: Biochemicals. Alternative Names: (all-Z)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Glycidyl Eicosapentaenoate-d5 Quick inquiry Where to buy Suppliers range | A labeled monoacylglycerol used in the preparation of triacylglycerols acylated with n-3 polyunsaturated fatty acids for nutritional applications. Group: Biochemicals. Alternative Names: (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid Glycidyl-d5 Ester; EPA Glycidyl-d5 Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Glycidyl Linoleate-d5 Quick inquiry Where to buy Suppliers range | Potential inhibitor of Monoacylglycerol Lipase. Group: Biochemicals. Alternative Names: (9Z,12Z)-9,12-Octadecadienoic Acid 2-Oxiranylmethyl Ester-d5; Linoleic Acid 2,3-Epoxypropyl Ester-d5; 2,3-Epoxypropyl Linoleate-d5; Linoleic Acid Glycidyl Ester-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Glycidyl Myristate-d5 Quick inquiry Where to buy Suppliers range | Labeled Glycidyl Myristate. A potential inhibitor of monoacylglycerol lipase. Group: Biochemicals. Alternative Names: Tetradecanoic Acid 2-Oxiranylmethyl-d5 Ester; Glycidyl-d5 Tetradecanoate; Myristic Acid Glycidyl-d5 Ester; NSC 404224-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
JW 618 Quick inquiry Where to buy Suppliers range | JW 618 is an inhibitor of monoacylglycerol lipase (MAGL), displaying IC50 values of 123, 385, and 6.9 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively. MAGL is a 33 kDa serine hydrolase that catalyses the hydrolysis of monoacylglycerols to their corresponding fatty acids. Synonyms: 1,1,1,3,3,3-hexafluoropropan-2-yl N-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate. Grades: ≥98%. CAS No. 1416133-88-4. Molecular formula: C17H14F6N2O2. Mole weight: 392.3. | |
JW 642 Quick inquiry Where to buy Suppliers range | Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the hydrolysis of 2-AG to arachidonic acid and glycerol, thus terminating its biological function. JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively. JW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s = 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively). Synonyms: JW642; JW-642; JW 642. Grades: >98%. CAS No. 1416133-89-5. Molecular formula: C21H20F6N2O3. Mole weight: 462.39. | |
JZL184 Quick inquiry Where to buy Suppliers range | JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM. Synonyms: JZL184; JZL 184; JZL-184. Grades: >98%. CAS No. 1101854-58-3. Molecular formula: C27H24N2O9. Mole weight: 520.49. | |
JZL195 Quick inquiry Where to buy Suppliers range | JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA), the endogenous ligands for the cannabinoid G-protein coupled receptors CB1 and CB2. IC50 values are 2 nM for MAGL and 4 nM for FAAH. JZL195 has been shown to inhibit endocannabinoid hydrolysis and elevate 2-AG and AEA levels in vivo. Synonyms: JZL195; JZL-195; JZL 195. Grades: >98%. CAS No. 1210004-12-8. Molecular formula: C24H23N3O5. Mole weight: 433.46. | |
KML-29 Quick inquiry Where to buy Suppliers range | KML-29 is an extremely specific monoacylglycerol lipase (MAGL) inhibitor. KML-2 should be useful to distinguish between actions of 2-arachidonoyl glycerol (an endogenous ligand of cannabinoid receptors that is deactivated by MAGL) and anandamide, another endocannabinoid. Group: Biochemicals. Alternative Names: 4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic Acid 2,2,2-Trifluoro-1-(trifluoromethyl)ethyl Ester; 1,1,1,3,3,3-Hexafluoropropan-2-yl 4- (Bis (benzo[d][1, 3]dioxol-5-yl) (hydroxy) methyl) piperidine-1-carboxylate; KML29. Grades: Highly Purified. CAS No. 1380424-42-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
LEI-106 Quick inquiry Where to buy Suppliers range | LEI-106 is a potent inhibitor of sn-1 DAGLα (IC50 = 18 nM). It inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6 in mouse brain membrane homogenates and in HEK293T cell membrane preparations. Synonyms: 2-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)sulfonyl-[(4-phenoxyphenyl)methyl]amino]acetic acid. Grades: ≥98%. CAS No. 1620582-23-1. Molecular formula: C26H27NO6S. Mole weight: 481.6. | |
MGAT2-IN-1 Quick inquiry Where to buy Suppliers range | An orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) (IC50= 7.8 for human, and 2.4 nM for mouse MGAT2). Synonyms: N-(4-chloro-2,6-difluorophenyl)-1-[5-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]pyrimidin-2-yl]-7-(2-oxopyrrolidin-1-yl)-2,3-dihydroindole-5-sulfonamide. CAS No. 1800025-30-2. Molecular formula: C27H21ClF5N7O3S. Mole weight: 654.01. | |
MJN110 Quick inquiry Where to buy Suppliers range | MJN110 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor that modulates the synaptic processes. MJN110 has the potential for the treatment of acute nausea and vomiting as well as anticipatory nausea by elevation of endogenous cannabinoid 2-arachidonoylglycerol (2-AG) levels in the brain. Uses: Antihyperalgesic agent. Synonyms: MJN-110; MJN 110; MJN110;2,5-dioxopyrrolidin-1-yl 4-(bis(4-chlorophenyl)methyl)piperazine-1-carboxylate. Grades: 98%. CAS No. 1438416-21-7. Molecular formula: C22H21Cl2N3O4. Mole weight: 462.33. | |
Monoacylglycerol Lipase Inhibitor 21 Quick inquiry Where to buy Suppliers range | MAGL inhibitor 21 is a potent and selective inhibitor of monoacylglycerol lipase (MAGL), an enzyme responsible for the inactivation of the endocannabinoid 2-arachidonoylglycerol (2-AG). It exhibits analgesic and tissue-protecting effects in animal models. Synonyms: MAGL Inhibitor 21; 1,3-Benzodioxol-5-ylmethyl 6-(4-phenylphenyl)hexanoate. Grades: ≥98%. CAS No. 1643657-35-5. Molecular formula: C26H26O4. Mole weight: 402.5. | |
N-Arachidonyl maleimide Quick inquiry Where to buy Suppliers range | N-Arachidonyl maleimide (NAM) is a potent and irreversible inhibitor of monoacylglycerol lipase (MAGL), an enzyme in the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). Synonyms: NAM; 1-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]pyrrole-2,5-dione. Grades: ≥98%. CAS No. 876305-42-9. Molecular formula: C24H35NO2. Mole weight: 369.5. | |
NF 1819 Quick inquiry Where to buy Suppliers range | NF 1819 is a selective irreversible β-lactam-based monoacylglycerol lipase inhibitor with IC50 values of 0.25 and 7.4 nM at rMAGL and hMAGL. Synonyms: NF-1819; NF 1819; NF1819; (3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone. Grades: ≥98% by HPLC. CAS No. 1881244-28-5. Molecular formula: C24H22FN5O4. Mole weight: 463.46. | |
URB754 Quick inquiry Where to buy Suppliers range | URB754 is a potent and non-competitive inhibitor of monoacylglycerol lipase (MAGL) with IC50 value of 200 nM for the recombinant rat brain enzyme. However, it does not inhibit human recombinant, rat brain, or mouse brain MAGL at concentrations up to 100 μM. The MAGL inhibitory activity of URB754 was reported to be attributed to the impurity bis(methylthio)mercurane (IC50 = 11.9 nM for rat recombinant MAGL) that is found in commercial samples. Synonyms: URB-754; URB 754; 6-methyl-2-(4-methylanilino)-3,1-benzoxazin-4-one. Grades: >98%. CAS No. 86672-58-4. Molecular formula: C16H14N2O2. Mole weight: 266.3. |