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United States Biological supplies a complete range of animal serum products for use in diagnostics and molecular biology research. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 100ml. US Biological Life Sciences.
Worldwide
Serum, Mouse a-Allotype, Strains CBA and Bra/Rij, Normal
Serum, Mouse a-Allotype, Strains CBA and Bra/Rij, Normal. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
Serum, Mouse, b-Allotype, Strains C57Bl and KalwRij, Normal
Serum, Mouse, b-Allotype, Strains C57Bl and KalwRij, Normal. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
Serum, Mouse, Normal
Normal mouse serum obtained from a donor population of adult Swiss webster mice (either sex). This preparation is non-sterile. Group: Biologicals. Grades: Serum. Pack Sizes: 5ml. US Biological Life Sciences.
Worldwide
244cis
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2956402-64-3. Pack Sizes: 1 mg (25.76 mM * 40 ?L in Ethanol). Product ID: HY-160552.
24-Nor 3β-Ursodeoxycholic Acid
24-Nor 3β-Ursodeoxycholic Acid is a side chain-shortened C23 homologue of Ursodeoxycholic Acid (UDCA) and has shown potent anti-cholestatic, anti-inflammatory, and anti-fibrotic properties. It is highly effective in preclinical mouse models of cholestatic and fibrotic liver diseases, significantly reducing serum alkaline phosphatase (ALP) levels in a dose-dependent fashion. Synonyms: (3β,5β,7β)-3,7-Dihydroxy-24-norcholan-23-oic Acid; 3β,7β-Dihydroxy-24-nor-5β-cholan-23-oic Acid; 3β-Norursodeoxycholic Acid; 24-Nor 3Beta-Ursodeoxycholic Acid; (R)-3-((3S,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)butanoic acid. Grade: ≥95%. Molecular formula: C23H38O4. Mole weight: 378.55.
Aspoxicillin
Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC 90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 63358-49-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135842.
Elobixibat
Elobixibat (A 3309; AZD 7806) is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor, with an IC 50 value of 0.53 nM (human IBAT ), 0.13 nM (mouse IBAT), 5.8 nM (canine IBAT). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 3309; AZD 7806. CAS No. 439087-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15790.
Native Mouse Creatine Kinase MM
Creatine kinase, muscle also known as CKM is a creatine kinase that in humans is encoded by the CKM gene. In the figure to the right, the crystal structure of the muscle-type M-CK monomer is shown. In vivo, two such monomers arrange symmetrically to form the active MM-CK enzyme. In heart, in addition to the MM-CK homodimer, also the heterodimer MB-CK consisting of one muscle (M-CK) and one brain-type (B-CK) subunit is expressed. The latter may be an important serum marker for myocardial infarction, if released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Group: Enzymes. Synonyms: CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; CK-MM. Purity: > 90% (SDS-PAGE). CK. Mole weight: 43 kDa. Storage: Store at -20° C. Form: Liquid, 50% Glycerol, 50 mM TrisCl, 2.5 mM b-mercaptoethanol, 0.05% NaN3. Source: Mouse Skeletal Muscle. Species: Mouse. CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; CK-MM. Cat No: NATE-1887.
Seladelpar Lysine dihydrate
Seladelpar (MBX-8025) Lysine dihydrate is the Lysine dihydrate salt form of Seladelpar (HY-19522). Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-δ , with EC 50 of 2 nM. Seladelpar Lysine dihydrate shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar Lysine dihydrate can be used for the study of primary biliary cholangitis. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate. CAS No. 928821-40-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19522C.
Streptozotocin
Streptozotocin is a monosaccharide antibiotic produced by Str. achromogenes 128 (NRRL 2697). It has antibacterial effect, and human serum and urine do not affect its activity. It can protect mice infected with Staphylococcus aureus, Pasteurella pestis and Proteus vulgaris. The same amount of antibiotic U-15774 can inhibit mouse sarcoma-180, sarcoma L5178Y, Walker-256 and Ehrlich carcinoma. Streptozotocin is a glucosamine-nitrosourea derivative, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent. It is commonly used for the treatment of metastatic pancreatic islet cell carcinoma. Uses: The treatment of metastatic pancreatic islet cell carcinoma. Synonyms: streptozosin; Estreptozocina. Grade: 95% (mixture of isomers). CAS No. 18883-66-4. Molecular formula: C8H15N3O7. Mole weight: 265.22.
Hepcidin-1 (mouse)
Two kinds of hepcidin are found in mice. Hepcidin-1, a homolog of human Hepcidin-25 in serum, may be involved in murine brain iron metabolism. Hepcidin-2 is a pentapeptide with different sequences in urine. Synonyms: H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys22, Cys11-Cys19, Cys13-Cys14); L-alpha-aspartyl-L-threonyl-L-asparagyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-asparagyl-L-seryl-L-glutaminyl-L-cysteinyl-glycyl-L-isoleucyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->22),(11->19),(13->14)-tetrakis(disulfide); L-α-Aspartyl-L-threonyl-L-asparaginyl-L-phenylalanyl-L-prolyl-N-[(1R,4R,7S,10S,13R,18R,21R,24S,30R,33S,36S,39S,42S,45R,50R,53S)-53-(4-aminobutyl)-18-{[(2S)-6-amino-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]amino}-1-oxo-2-hexanyl]carbamoyl}-39,42-bis(2-amino-2-oxoethyl)-33-(3-amino-3-oxopropyl)-7-benzyl-10,24-di[(2S)-2-butanyl]-36-(hydroxymethyl)-3,6,9,12,20,23,26,29,32,35,38,41,44,52,55,60-hexadecaoxo-15,16,47,48,57,58,63,64-octathia-2,5,8,11,19,22,25,28,31,34,37,40,43,51,54,61-hexadecaazatetracyclo[28.25.4.44,21.245,50]pentahexacont-13-yl]-L-isoleucinamide. Grade: ≥95%. CAS No. 1676104-75-8. Molecular formula: C111H169N31O35S8. Mole weight: 2754.28.
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