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| Product | Description | |
|---|---|---|
| Serum, Mouse | United States Biological supplies a complete range of animal serum products for use in diagnostics and molecular biology research. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 100ml. US Biological Life Sciences. |  Worldwide |
| Serum, Mouse a-Allotype, Strains CBA and Bra/Rij, Normal | Serum, Mouse a-Allotype, Strains CBA and Bra/Rij, Normal. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Serum, Mouse, b-Allotype, Strains C57Bl and KalwRij, Normal | Serum, Mouse, b-Allotype, Strains C57Bl and KalwRij, Normal. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Serum, Mouse, Normal | Normal mouse serum obtained from a donor population of adult Swiss webster mice (either sex). This preparation is non-sterile. Group: Biologicals. Grades: Serum. Pack Sizes: 5ml. US Biological Life Sciences. | Worldwide |
| Aspoxicillin | Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC 90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 63358-49-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135842. |  |
| Elobixibat | Elobixibat (A 3309; AZD 7806) is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor, with an IC 50 value of 0.53 nM (human IBAT ), 0.13 nM (mouse IBAT), 5.8 nM (canine IBAT). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 3309; AZD 7806. CAS No. 439087-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15790. | |
| Native Mouse Creatine Kinase MM | Creatine kinase, muscle also known as CKM is a creatine kinase that in humans is encoded by the CKM gene. In the figure to the right, the crystal structure of the muscle-type M-CK monomer is shown. In vivo, two such monomers arrange symmetrically to form the active MM-CK enzyme. In heart, in addition to the MM-CK homodimer, also the heterodimer MB-CK consisting of one muscle (M-CK) and one brain-type (B-CK) subunit is expressed. The latter may be an important serum marker for myocardial infarction, if released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Group: Enzymes. Synonyms: CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; CK-MM. Purity: > 90% (SDS-PAGE). CK. Mole weight: 43 kDa. Storage: Store at -20° C. Form: Liquid, 50% Glycerol, 50 mM TrisCl, 2.5 mM b-mercaptoethanol, 0.05% NaN3. Source: Mouse Skeletal Muscle. Species: Mouse. CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; CK-MM. Cat No: NATE-1887. |  |
| NPS-1034 | NPS-1034 is a novel MET inhibitor, which inhibits the activated MET receptor and its constitutively active mutants. NPS-1034, inhibits various constitutively active mutant forms of MET as well as HGF-activated wild-type MET. NPS-1034 inhibited the proliferation of cells expressing activated MET and promoted the regression of tumors formed from such cells in a mouse xenograft model through anti-angiogenic and pro-apoptotic actions. NPS-1034 also inhibited HGF-stimulated activation of MET signaling in the presence or absence of serum. Notably, NPS-1034 inhibited three MET variants that are resistant to the MET inhibitors SU11274, NVP-BVU972, and PHA665752. Synonyms: NPS-1034; NPS1034; NPS 1034. Grades: 98%. CAS No. 1221713-92-3. Molecular formula: C31H23F2N5O3. Mole weight: 551.554. |  |
| Pluripotin | SC1 (Pluripotin) was identified in a cell-based chemical library screen for small molecules that regulate mouse embryonic stem (ES) cell self-renewal. SC1 is sufficient to sustain long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP). Mouse ES cells maintained in the presence of SC1 retain their ability to differentiate into cells representing all three germ layers in vitro, form chimeric mouse, and contribute to germ line in vivo. Uses: Self-renewal. Synonyms: SC-1; SC 1; SC1; Pluripotin. Grades: 0.98. CAS No. 839707-37-8. Molecular formula: C27H25F3N8O2. Mole weight: 550.54. | |
| Seladelpar Lysine dihydrate | Seladelpar (MBX-8025) Lysine dihydrate is the Lysine dihydrate salt form of Seladelpar (HY-19522). Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-δ , with EC 50 of 2 nM. Seladelpar Lysine dihydrate shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar Lysine dihydrate can be used for the study of primary biliary cholangitis. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate. CAS No. 928821-40-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19522C. | |
| SR 1903 | SR 1903 is an inverse agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and an agonist of liver X receptor (LXR). It also binds to PPARγ without activity. It reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity. Synonyms: 1-[2'-Methyl-4'-[[4-(4-pyridylmethyl)-1-piperazinyl]methyl]-4-biphenylyl]-1-(trifluoromethyl)-2,2,2-trifluoroethanol. Grades: ≥98%. CAS No. 1414248-06-8. Molecular formula: C27H27F6N3O. Mole weight: 523.51. | |
| Hepcidin-1 (mouse) | Two kinds of hepcidin are found in mice. Hepcidin-1, a homolog of human Hepcidin-25 in serum, may be involved in murine brain iron metabolism. Hepcidin-2 is a pentapeptide with different sequences in urine. Synonyms: H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys22, Cys11-Cys19, Cys13-Cys14); L-alpha-aspartyl-L-threonyl-L-asparagyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-asparagyl-L-seryl-L-glutaminyl-L-cysteinyl-glycyl-L-isoleucyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->22),(11->19),(13->14)-tetrakis(disulfide); L-α-Aspartyl-L-threonyl-L-asparaginyl-L-phenylalanyl-L-prolyl-N-[(1R, 4R, 7S, 10S, 13R, 18R, 21R, 24S, 30R, 33S, 36S, 39S, 42S, 45R, 50R, 53S)-53-(4-aminobutyl)-18-{[(2S)-6-amino-1-{[(1S, 2R)-1-carboxy-2-hydroxypropyl]amino}-1-oxo-2-hexanyl]carbamoyl}-39, 42-bis(2-amino-2-oxoethyl)-33-(3-amino-3-oxopropyl)-7-benzyl-10, 24-di[(2S)-2-butanyl]-36-(hydroxymethyl)-3, 6, 9, 12, 20, 23, 26, 29, 32, 35, 38, 41, 44, 52, 55, 60-hexadecaoxo-15, 16, 47, 48, 57, 58, 63, 64-octathia-2, 5, 8, 11, 19, 22, 25, 28, 31, 34, 37, 40, 43, 51, 54, 61-hexadecaazatetracyclo[28.25.4.44, 21.245, 50]pentahexacont-13-yl]-L-isoleucinamide. Grades: ≥95%. CAS No. 1676104-75-8. Molecular formula: C111H169N31O35S8. Mole weight: 2754.28. | |
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