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HDAC 1 inhibitor. Antitumor compound. Antiproliferative. TGF-beta type II receptor inducer. Apoptosis inducer. Anti-inflammatory. Angiogenesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 209783-80-2. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C21H20N4O3. US Biological Life Sciences.
Worldwide
MS-275 (Entinostat, SNDX-275)
Preferentially inhibits HDAC1 (IC50=300 nM) over HDAC3 (IC50=8uM). Has no inhibitory activity towards HDAC8 (IC50>100uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 209783-80-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
24, 25-Dihydroxy VD2
24, 25-Dihydroxy VD2 is a hydroxylated metabolite of Vitamin D2, which is a synthetic analog of Vitamin D. Synonyms: 24, 25-Dihydroxy VD2; 58050-55-8; (E,6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2,3-dimethylhept-4-ene-2,3-diol; 24,25-Dihydroxy Vitamin D2; CS-0802; DTXSID80735363; HY-76801; MS-27598; PD100785; 24,25-Dihydroxy Vitamin D2 (mixture of diastereomers); (3S,5Z,7E,22E,24xi)-9,10-Secoergosta-5,7,10,22-tetraene-3,24,25-triol. Grade: >98%. CAS No. 58050-55-8. Molecular formula: C28H44O3. Mole weight: 428.65.
AChE-IN-3
AChE-IN-3 has moderate inhibitory activity against AChE and strong NO inhibitory activity with an EC50 of 0.57 μM. Synonyms: AChE-IN-3; 2713548-95-7; EX-A8068; AKOS040757991; MS-27552; HY-145112; CS-0356435. CAS No. 2713548-95-7. Molecular formula: C25H21N3O4. Mole weight: 427.45.
Entinostat
Entinostat is a histone deacetylase (HDAC) inhibitor displaying antiproliferative and antineoplastic effects. Entinostat induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), which slows cell growth, differentiation, and tumor development in vivo. Entinostat is potentially used as an antitumor drug in combination with other drugs like adriamycin, PARP inhibitors and Hsp90 inhibitors. Uses: Histone deacetylase inhibitors. Synonyms: MS275; MS-275; MS 2275; SNDX275; SNDX-275; SNDX 275; Entinostat; pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate. Grade: > 98%. CAS No. 209783-80-2. Molecular formula: C21H20N4O3. Mole weight: 376.416.
Entinostat
Entinostat is an oral and selective class I HDAC inhibitor, with IC 50 s of 243 nM, 453 nM, and 248 nM for HDAC1 , HDAC2 , and HDAC3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MS-275; SNDX-275. CAS No. 209783-80-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12163.
yadanziolide A
Yadanziolide A is extracted from seeds of Brucea javanica. It has strong antiviral activity. Synonyms: yadanziolide A; 95258-14-3; (1R,2R,3R,6R,8S,12S,13S,14R,15R,16S,17R)-2,3,12,15,16-Pentahydroxy-17-(hydroxymethyl)-9,13-dimethyl-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-4,11-dione; CHEMBL2037039; HY-N4210; AKOS040760154; AC-34985; DA-61914; MS-27518; CS-0032442; G18579; (1R,2R,3R,6R,8S,12S,13S,14R,15R,16S,17R)-2,3,12,15,16-pentahydroxy-17-(hydroxymethyl)-9,13-dimethyl-5,18-dioxapentacyclo[12.5.0.0(1),?.0(2),(1)?.0?,(1)(3)]nonadec-9-ene-4,11-dione. Grade: 98.0%. CAS No. 95258-14-3. Molecular formula: C23H30O9. Mole weight: 450.5.
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