Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| MT1 | MT1 is a bivalent chemical probe of BET bromodomains , with an IC 50 of 0.789 nM for BRD4(1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2060573-82-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111976. |  |
| MT1-MMP Inhibitor, NSC405020 | The MT1-MMP Inhibitor, NSC405020 controls the biological activity of MT1-MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. |  |
| MT1-MMP Inhibitor, NSC405020 (3,4-Dichloro-N-(1-methylbutyl)benzamide, 3,4-Dichloro-N-(pentan-2-yl)benzamide) | A cell-permeable pentanylbenzamide compound that acts as an allosteric, reversible, and selective inhibitor of the collgenolytic activity of MT1-MMP. Does not affect the catalytic activity of cellular MT-1-MMP thus allows it to retain its ability to activate MMP-2. Selectively targets the hemopexin (PEX) domain of MT1-MMP, thereby repressing its pro-tumorigenic activity. Its binding to the PEX domain is dependent on Met-328, Arg-330, Asp-376, Met-422, and Ser-470 in the druggable pocket of the enzyme. Shown to block 184B5-MT cell migration on collagen-1 and repress MCF7-b3/MT tumor growth in xenografted mice (0.5mg/kg, intratumoral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| (1,2,6,7,-Tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile | (1,2,6,7,-Tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Ramelteon. Synonyms: 2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile; Dihydro-1H-indeno[5,4-B]furan-8(2H)-ylidene)acetonitrile. Grades: >95%. CAS No. 221530-44-5. Molecular formula: C13H11NO. Mole weight: 197.23. |  |
| 1-(2-aminoethyl)-6-methoxyindan | 1-(2-aminoethyl)-6-methoxyindan is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: 2,3-Dihydro-6-methoxy-1H-indene-1-ethanamine; rac-2,3-Dihydro-6-methoxy-1H-indene-1-ethanamine. Grades: 95%. CAS No. 108048-37-9. Molecular formula: C12H17NO. Mole weight: 191.27. | |
| 1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-acetamide | 1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-acetamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Grades: >90%. CAS No. 1053239-38-5. Molecular formula: C13H15NO2. Mole weight: 217.26. | |
| (2E)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)acetonitrile | (2E)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)acetonitrile is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: (E)-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)acetonitrile; (E)-(6-methoxyindan-1-ylidene)acetonitrile. Grades: 95%. CAS No. 187871-98-3. Molecular formula: C12H11NO. Mole weight: 185.22. | |
| 2-Iodomelatonin | 2-Iodomelatonin is a potent agonist of the melatonin receptors 1 (MT1) with Ki value of 28 pM. It could be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues. It inhibits forskolin-stimulated cAMP production in CHO cells expressing human MT1 30-fold more potently than melatonin. It has been used to characterize the role of MT1 in melatonin-mediated signaling. It is useful in receptor binding studies with radioactive iodomelatonin. Synonyms: N-[2-(2-Iodo-5-methoxyindol-3-yl)ethyl]acetamide; N-Acetyl-2-iodo-5-methoxytryptamine. Grades: ≥98% by HPLC. CAS No. 93515-00-5. Molecular formula: C13H15IN2O2. Mole weight: 358.18. | |
| 2-Iodomelatonin | Potent melatonin agonist (pKi values are 10.55 and 9.87 at human recombinant MT1 and MT2 receptors respectively). 2-[125I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues. Group: Biochemicals. Grades: Highly Purified. CAS No. 93515-00-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| (2Z)-(6-Methoxy-2,3-dihydro-1H-inden-1-ylidene)acetonitrile | (2Z)-(6-Methoxy-2,3-dihydro-1H-inden-1-ylidene)acetonitrile is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: A byproduct formed during the production of ramelteon. Synonyms: (Z)-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)acetonitrile; (2Z)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)acetonitrile. CAS No. 468104-14-5. Molecular formula: C12H11NO. Mole weight: 185.22. | |
| 4,5-dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one | 4,5-dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep medication used to treat sleeplessness (insomnia). Synonyms: 4,5-Dibromo-6,7-dihydro-1H-indeno[5,4-b]furan-8(2H)-one; Ramelteon Impurity I. CAS No. 196597-77-0. Molecular formula: C11H8Br2O2. Mole weight: 331.99. | |
| 4-Acetyl Ramelteon | 4-Acetyl Ramelteon is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: N-[2-(4-Acetyl-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl])ethyl]propanamide. Grades: >95%. CAS No. 1346598-94-4. Molecular formula: C18H23NO3. Mole weight: 301.38. | |
| 4-Hydroxy Ramelteon | 4-Hydroxy Ramelteon is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: A metabolite of ramelteon (r110051). Synonyms: (S)-N-(2-(4-hydroxy-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl)propionamide. Grades: >95%. CAS No. 1204581-50-9. Molecular formula: C16H21NO3. Mole weight: 275.34. | |
| 4-Hydroxy Ramelteon β-D-Glucuronide | 4-Hydroxy Ramelteon β-D-Glucuronide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Molecular formula: C22H29NO9. Mole weight: 451.47. | |
| 4-Hydroxy Ramelteon beta-D-Glucuronide | 4-Hydroxy Ramelteon beta-D-Glucuronide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: 4-Hydroxy Ramelteon ?-D-Glucuronide; 4-Hydroxy Ramelteon beta-D-Glucuronide. Molecular formula: C22H29NO9. Mole weight: 451.47. | |
| 4-P-PDOT | 4-P-PDOT is an antagonist of the melatonin 2 (MT2) receptor (pKi = 8.37) that displays 60-fold selectivity for MT2 over MT1. Synonyms: AH 024; cis-4-phenyl-2-Propionamidotetralin; N-(4-Phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide. Grades: ≥98%. CAS No. 134865-74-0. Molecular formula: C19H21NO. Mole weight: 279.4. | |
| 4-P-PDOT | 4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist. 4-P-PDOT is >300-fold more selective for MT2 than MT1. 4-P-PDOT significantly counteracts Melatonin-mediated antioxidant effects (GSH/GSSG ratio, phospho-ERK, Nrf2 nuclear translocation, Nrf2 DNA-binding activity)[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 134865-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100609. | |
| 8-M-PDOT | 8-M-PDOT is a melatonin receptor agonist, with 20-fold selective for the MT2 (vs MT1) subtype (pKi = 8.23 and 8.95 at human recombinant MT1 and MT2 receptors respectively). Synonyms: 8-Methoxy-2-propionamidotetralin. Grades: ≥99% by HPLC. CAS No. 134865-70-6. Molecular formula: C14H19NO2. Mole weight: 233.31. | |
| Afobazole | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346; Afobazol; Fabomotizole; CM 346; CM-346. Grades: >98%. CAS No. 173352-21-1. Molecular formula: C15H21N3O2S. Mole weight: 307.41. | |
| Afobazole hydrochloride | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346 hydrochloride; Afobazol hydrochloride; Fabomotizole hydrochloride; CM 346 hydrochloride; CM-346 hydrochloride. Grades: >98%. CAS No. 173352-39-1. Molecular formula: C15H22ClN3O2S. Mole weight: 343.87. | |
| Agomelatine | Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098. CAS No. 138112-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038. | |
| Agomelatine hydrochloride | Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098 hydrochloride. CAS No. 1176316-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038A. | |
| Amiselimod HCl | Amiselimod, formerly known as MT-1303, is a prodrug that is converted to (S)-amiselimod phosphate by sphingosine kinases. And it also is a potent and selective immunosuppressant and sphingosine 1 phosphate receptor modulator, as an investigational therapy for people with relapsing-remitting muscular sclerosis (RRMS), inflammatory bowel disease (IBD), and other autoimmune diseases. Synonyms: 2-amino-2-{2-[4- (heptyloxy) -3- (trifluoromethyl) phenyl]ethyl}propane-1, 3-diol hydrochloride; MT-1303; MT1303; MT 1303; Amiselimod HCl. CAS No. 942398-84-7. Molecular formula: C19H31ClF3NO3. Mole weight: 413.91. | |
| DH 97 | DH 97 is a potent MT2 melatonin receptor antagonist (pKi = 8.03) with 89- and 229-fold selectivity over MT1 and GPR50 (melatonin-related orphan receptor) respectively. Synonyms: DH-97; DH 97; DH97; N-Pentanoyl-2-benzyltryptamine; N-[2-(2-benzyl-1H-indol-3-yl)ethyl]pentanamide. CAS No. 220339-00-4. Molecular formula: C22H26N2O. Mole weight: 334.46. | |
| (E)-1-(2-Aminoethylidene)-6-methoxyindan | (E)-1-(2-Aminoethylidene)-6-methoxyindan is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: (E)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethanamine; (2E)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethanamine. CAS No. 178676-73-8. Molecular formula: C12H15NO. Mole weight: 189.25. | |
| (E)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylidene)ethylamine | (E)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylidene)ethylamine is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the preparation of ramelteon. Synonyms: 2-[(8E)-1H,2H,6H,7H,8H-indeno[5,4-b]furan-8-ylidene]ethan-1-amine; 2-[(E)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylidene]ethylamine. Grades: >95%. CAS No. 196597-61-2. Molecular formula: C13H15NO. Mole weight: 201.26. | |
| (E)-N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethyl]propanamide | (E)-N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the preparation of ramelteon. Synonyms: N-[(2E)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethyl]propanamide. Grades: >95%. CAS No. 196597-82-7. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
| GR 135531 | GR 135531 is a high affinity agonist of MT3 melatonin receptors, with low affinity for MT1 and MT2 melatonin receptors. GR 135531 can be used to discriminate between the melatonin receptor subtypes. Synonyms: GR 135531; GR135531; GR-1355315-Methoxycarbonylamino-N-acetyltryptamine; 5-MCA-NAT; methyl N-[3-(2-acetamidoethyl)-1H-indol-5-yl]carbamate. Grades: ≥97% by HPLC. CAS No. 190277-13-5. Molecular formula: C14H17N3O3. Mole weight: 275.31. | |
| Luzindole | Luzindole is a melatonin receptor antagonist which preferentially targets MT1B. Synonyms: Luzindole, N-0774, N0774, N 0774, N-acetyl-2-benzyltryptamine. Grades: ≥99% by HPLC. CAS No. 117946-91-5. Molecular formula: C19H20N2O. Mole weight: 292.38. | |
| Luzindole | Luzindole (N-0774) is a selective melatonin receptor antagonist. Luzindole preferentially targets MT2 (Mel 1b ) over MT1 (Mel 1a ) with K i values of 10.2 and 158 nM for human MT2 and MT1, respectively. Luzindole suppresses experimental autoimmune encephalomyelitis (EAE), and exerts antidepressant-like activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-0774. CAS No. 117946-91-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101254. | |
| LY 156735 | This active molecular is high affinity nonselective melatonin receptors MT1 and MT2 agonist which is under development for the treatment of insomnia and other sleep disorders. Its agonist action on MT1 and MT2 receptors in the suprachiasmatic nucleus in the brain enables its action as a chronobiotic. The action of LY 156735 on MT1 and MT2 receptors promots sleeping because melatonin's effects at these same receptors is linked with maintenance of normal-sleep wake cycle. The EC50 value of LY 156735 is 0.0479nM, compared to 0.063nM for melatonin. In May 2004, LY 156735 had received orphan drug status for the treatment of circadian sleep disorders in totally blind individuals in the US. In Nov 2005, data which was presented at the 18th Annual Congress of the European College of Neuropsychopharmacology had been added to the adverse events and Anxiety disorders therapeutic trials sections. Uses: The treatment of insomnia and other sleep disorders. Synonyms: LY 156735; LY156735; LY-156735; TIK-301; TIK 301; TIK301; N-[(2R)-2-(6-chloro-5-methoxy-1H-indol-3-yl)propyl]acetamide. Grades: 98%. CAS No. 118702-11-7. Molecular formula: C14H17ClN2O2. Mole weight: 280.75. | |
| Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1[1]. (Ex/Em=325 nm/400 nm). Uses: Scientific research. Group: Peptides. Alternative Names: Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2. CAS No. 720710-69-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4931. | |
| MMP-9 Inhibitor II (MMP-9 PEX Inhibitor) | This compound is a cell-permeable, selective, and reversible thiopyrimidone MMP-9 allosteric inhibitor that binds specifically to the non-catalytic site of MMP-9 at the PEX domain with a =2.1uM and thereby disrupts MMP-9 homodimerization and its cross-talk with CD44 and the EGFR-MAPK signaling pathway. It does not bind to the PEX domain of MMP-2 or MT1-MMP and it is shown to decrease MMP-9 mediated cell migration in COS-1 cells at 100uM. Also, it inhibits cell migration and invasion of HT-1080 and MDA-MB-435 human cancer cells in a dose-dependent manner from 0.1 to 100M, without altering MMP-9 expression or proteolytic activity in HT-1080 cells. In addition, it attenuates both primary tumor growth and metastasis in vivo in a mouse model without obvious toxicity (20mg/kg, 6 days/week, i.v. and i.t.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-[2-[(1S)-5-bromo-2,3-dihydro-6-(2-propen-1-yloxy)-1H-inden-1-yl]ethyl]propanamide | N-[2-[(1S)-5-bromo-2,3-dihydro-6-(2-propen-1-yloxy)-1H-inden-1-yl]ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (S)-N-[2-[5-bromo-2,3-dihydro-6-(2-propenyloxy)-1H-inden-1-yl]ethyl]propanamide; (S)-N-[2-(6-allyloxy-5-bromoindan-1-yl)ethyl]propionamide. Grades: >95%. CAS No. 196597-85-0. Molecular formula: C17H22BrNO2. Mole weight: 352.27. | |
| Naphthofluorescein | Naphthofluorescein is a furin inhibitor that inhibits furin-mediated cleavage of the pro-form of membrane type-1 matrix metalloproteinase (MT1-MMP), resulting in decreased levels of active MT1-MMP. Naphthofluorescein is a red-emitting fluorescent probe for hydrogen peroxide in living cells. Synonyms: CCG 8295. Grades: ≥98%. CAS No. 61419-02-1. Molecular formula: C28H16O5. Mole weight: 432.4. | |
| NSC 405020 | NSC-405020 is a novel small molecule inhibitor of MT1-MMP that specifically targets PEX domain rather than the catalytic domain of MT1-MMP with IC50 >100 μM and does not inhibit the catalytic activity of MT1-MMP or MMP-2. Synonyms: TWS119; TWS 119; TWS-119. CAS No. 7497-7-6. Molecular formula: C12H15Cl2NO. Mole weight: 260.158. | |
| Rac-N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-yl)ethyl]propanamide | Rac-N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-yl)ethyl]propanamide is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: N-[2-(2,3-Dihydro-6-methoxy-1H-inden-1-yl)ethyl]propanamide; N-[2-(6-Methoxy-indan-1-yl)-ethyl]-propionamide. CAS No. 178677-89-9. Molecular formula: C15H21NO2. Mole weight: 247.33. | |
| rac Ramelteon-d3 (rac N-[-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide-d3, rac TAK-375-d3, rac Rozerem-d3) | Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic. Group: Biochemicals. Alternative Names: rac N-[-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide-d3; rac TAK-375-d3; rac Rozerem-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ramelteon | Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic. Group: Biochemicals. Alternative Names: N-[-[(8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide; TAK-375; Rozerem. Grades: Highly Purified. CAS No. 196597-26-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ramelteon | Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (S)-N-[2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl]propionamide; TAK-375. Grades: >98%. CAS No. 196597-26-9. Molecular formula: C16H21NO2. Mole weight: 259.34. | |
| Ramelteon | Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with Ki values of 14 and 112 pM, respectively. Ramelteon has the potential for the research of insomnia. Ramelteon consistently reduces sleep onset after long-term treatment, with no next-morning residual effects or rebound insomnia or withdrawal symptoms upon discontinuation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-375. CAS No. 196597-26-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0014. | |
| Ramelteon Impurity 1 | Ramelteon Impurity 1 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: 2-(7,8-Dihydro-6H-indeno[5,4-b]furan-8-yl)ethan-1-amine. Grades: > 95%. Molecular formula: C13H15NO. Mole weight: 201.26. | |
| Ramelteon Impurity 10 | Ramelteon Impurity 10 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: Ramelteon Chiral amide impurity. Grades: >98%. CAS No. 1149757-30-1. Molecular formula: C22H21NO4. Mole weight: 363.41. | |
| Ramelteon Impurity 11 | Ramelteon Impurity 11 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: Ramelteon Impurity IV. Grades: > 95%. Molecular formula: C32H40N2O4. Mole weight: 516.67. | |
| Ramelteon Impurity 12 | Ramelteon Impurity 12 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (S)-2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)acetonitrile. Grades: >98%. CAS No. 1185516-79-3. Molecular formula: C13H13NO. Mole weight: 199.25. | |
| Ramelteon Impurity 13 | Ramelteon Impurity 13 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-acetamide. Grades: >95%. CAS No. 221530-38-7. Molecular formula: C13H15NO2. Mole weight: 217.26. | |
| Ramelteon Impurity 14 | Ramelteon Impurity 14 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: Ramelteon Acetyl impurity; N-[2-[(8S)?-1,?6,?7,?8-Tetrahydro-2H-indeno[5,?4-b]?furan-8-yl]?ethyl]?acetamide. CAS No. 326793-94-6. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
| Ramelteon Impurity 15 | Ramelteon Impurity 15 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: Despropionyl Ramelteon; (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine. Grades: 95%. CAS No. 196597-81-6. Molecular formula: C13H17NO. Mole weight: 203.28. | |
| Ramelteon Impurity 15 Hydrochloride | Ramelteon Impurity 15 Hydrochloride is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Ramelteon (r110051) intermediate. Synonyms: Despropionyl Ramelteon Hydrochloride; (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine Hydrochloride. Grades: 95%. CAS No. 196597-80-5. Molecular formula: C13H17NO.HCl. Mole weight: 239.74. | |
| Ramelteon Impurity 16 | Ramelteon Impurity 16 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (E)-6,7-Dihydro Ramelteon; (E)-N-(2-(6,7-Dihydro-1H-indeno[5,4-b]furan-8(2H)-ylidene)ethyl)propionamide. CAS No. 1365920-11-1. Molecular formula: C16H19NO2. Mole weight: 257.33. | |
| Ramelteon Impurity 17 | Ramelteon Impurity 17 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: Ramelteon Stage-2 Dimer Impurity; Bis(2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl)amine. Grades: >95%. CAS No. 1365920-38-2. Molecular formula: C26H31NO2. Mole weight: 389.54. | |
| Ramelteon Impurity 18 | Ramelteon Impurity 18 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: Ramelteon Dimer Impurity. Molecular formula: C29H35NO3. Mole weight: 445.59. | |
| Ramelteon Impurity 19 | Ramelteon Impurity 19 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: Ramelteon Double bond amide impurity. CAS No. 1149757-29-8. Molecular formula: C22H19NO4. Mole weight: 361.39. | |
| Ramelteon Impurity 1 HCl | Ramelteon Impurity 1 HCl is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: 2-(7,8-Dihydro-6H-indeno[5,4-b]furan-8-yl)ethan-1-amine hydrochloride. CAS No. 1252018-54-4. Molecular formula: C13H15NO.HCl. Mole weight: 237.72. | |
| Ramelteon Impurity 2 | Ramelteon Impurity 2 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: 2H-Indeno[5,4-b]furan-8-ol, 1,6,7,8-tetrahydro-; 1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ol; 1H,2H,6H,7H,8H-Indeno[5,4-b]furan-8-ol; 2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-ol. Grades: 95%. CAS No. 1092507-07-7. Molecular formula: C11H12O2. Mole weight: 176.21. | |
| Ramelteon Impurity 20 | Ramelteon Impurity 20 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)acetic acid. CAS No. 1092507-02-2. Molecular formula: C13H14O3. Mole weight: 218.25. | |
| Ramelteon Impurity 21 | Ramelteon Impurity 21 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (R)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)acetic acid. CAS No. 1092507-03-3. Molecular formula: C13H14O3. Mole weight: 218.25. | |
| Ramelteon Impurity 22 | Ramelteon Impurity 22 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: N-[2-(7,8-Dihydro-6H-indeno[5,4-b]furan-8-yl)ethyl]propanamide. CAS No. 1252018-55-5. Molecular formula: C16H19NO2. Mole weight: 257.33. | |
| Ramelteon Impurity 23 | Ramelteon Impurity 23 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Molecular formula: C16H21NO4. Mole weight: 291.34. | |
| Ramelteon Impurity 24 | Ramelteon Impurity 24 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: 6-Oxo-ramelteon; N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide; Ramelteon Metabolite H. CAS No. 896736-22-4. Molecular formula: C16H19NO3. Mole weight: 273.33. | |
| Ramelteon Impurity 25 | Ramelteon Impurity 25 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Molecular formula: C17H21NO3. Mole weight: 287.35. | |
| Ramelteon Impurity 26 | Ramelteon Impurity 26 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Molecular formula: C16H19NO2. Mole weight: 257.33. | |
| Ramelteon Impurity 27 | Ramelteon Impurity 27 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: GQN8VYN6G3; Propanamide, N-[2-(1,6-dihydro-2H-indeno[5,4-b]furan-8-yl)ethyl]-; UNII-GQN8VYN6G3; N-(2-(1,6-Dihydro-2H-indeno(5,4-b)furan-8-yl)ethyl)propanamide; Propanamide, N-(2-(1,6-dihydro-2H-indeno(5,4-b)furan-8-yl)ethyl)-; N-[2-(2,6-dihydro-1H-cyclopenta[e][1]benzofuran-8-yl)ethyl]propanamide; SCHEMBL1566409; EN300-23537652; L017219; Z5039886990; N-(2-{1H,2H,6H-indeno[5,4-b]furan-8-yl}ethyl)propanamide. CAS No. 196597-30-5. Molecular formula: C16H19NO2. Mole weight: 257.33. | |
| Ramelteon Impurity 28 | Ramelteon Impurity 28 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (R)-N-(2-(7,8-dihydro-6H-indeno[5,4-b]furan-8-yl)ethyl)propionamide. Molecular formula: C16H19NO2. Mole weight: 257.33. | |
| Ramelteon Impurity 3 | Ramelteon Impurity 3 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (S)-N-[2-(7,8-Dihydro-6H-cyclopenta[e][1]benzofuran-8-yl)ethyl]propanamide. Grades: > 95%. CAS No. 880152-62-5. Molecular formula: C16H19NO2. Mole weight: 257.33. | |
| Ramelteon Impurity 4 | Ramelteon Impurity 4 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Grades: > 95%. Molecular formula: C26H32N2O2. Mole weight: 404.54. | |
| Ramelteon Impurity 5 | Ramelteon Impurity 5 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one; 6,7-dihydro-1H-indeno[5,4-b]furan-8(2H)-one. Grades: > 95 %. CAS No. 196597-78-1. Molecular formula: C11H10O2. Mole weight: 174.20. | |
| Ramelteon Impurity 7 | Ramelteon Impurity 7 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Ramelteon (r110050) intermediate. Synonyms: 2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-amine hydrochloride; Ramelteon Stage-2 Impurity. Grades: 95%. CAS No. 448964-37-2. Molecular formula: C13H17NO. Mole weight: 203.28. | |
| Ramelteon Impurity 7 HCl | Ramelteon Impurity 7 HCl is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: 2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-amine hydrochloride; Ramelteon Stage-2 Impurity HCl. Grades: >98%. CAS No. 1053239-39-6. Molecular formula: C13H17NO.HCl. Mole weight: 239.74. | |
| Ramelteon Impurity 8 | Ramelteon Impurity 8 is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: A receptor agonist; a therapeutic agent for sleep disorders. Synonyms: 6,7-Dibromo-2,3-dihydro-5-benzofuranpropanoic Acid; 3-(6,7-Dibromo-2,3-dihydrobenzofuran-5-yl)propanoic Acid. CAS No. 196597-76-9. Molecular formula: C11H10Br2O3. Mole weight: 350. | |
Our database is helping our users find suppliers everyday.
