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| Product | Description | |
|---|---|---|
| N-Methyl-D-aspartic acid (NMDA) | NMDA?N-Methyl-D-aspartic acid?is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Group: Biochemicals. Alternative Names: (R)-2-(Methylamino)succinic acid; NMDA; N-Methyl-D-aspartate. Grades: Highly Purified. CAS No. 6384-92-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C?H?NO?, Molecular Weight: 147.13. US Biological Life Sciences. |  Worldwide |
| (1S,2R)-cis-4-Cyclohexene-1,2-dicarboxylic Acid 1-Monomethyl Ester | (1S,2R)-cis-4-Cyclohexene-1,2-dicarboxylic Acid 1-Monomethyl Ester acts as a reagent in the asymmetric synthesis of unnatural β-amino acids, and also in the selective preparation of N-methyl-D-aspartic acid (NMDA) antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 88335-93-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H12O4, Molecular Weight: 184.19. US Biological Life Sciences. | Worldwide |
| Glycine | Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 56-40-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0966. |  |
| Glycine-13C2 | Glycine- 13 C 2 is the 13 C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 67836-01-5. Pack Sizes: 10 mg; 25 mg. Product ID: HY-Y0966S3. | |
| Glycine-15N | Glycine- 15 N is the 15 N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 7299-33-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-Y0966S. | |
| Glycine-2-13C | Glycine-2- 13 C is the 13 C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 20220-62-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-Y0966S2. | |
| Glycine-2-13C,15N | Glycine-2- 13 C, 15 N is the 13 C- and 15 N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 91795-59-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-Y0966S7. | |
| Glycine (Standard) | Glycine (Standard) is the analytical standard of Glycine. This product is intended for research and analytical applications. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 56-40-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0966R. | |
| NMDA | NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Uses: Scientific research. Group: Natural products. Alternative Names: N-Methyl-D-aspartic acid. CAS No. 6384-92-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-17551. | |
| N-Methyl-DL-aspartic acid | N-Methyl-DL-aspartic acid. Uses: Designed for use in research and industrial production. CAS No. 17833-53-3. Purity: 0.95. Product ID: ACM17833533-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-(methylamino)butanedioic acid, N-Methyl-D-aspartic acid. |  |
| 7-Chlorokynurenic acid | 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor ( IC 50 =0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a K i of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-CKA. CAS No. 18000-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100811. | |
| CGP 39551 | Cgp 39551 is a selective and competitive N-methyl-D-aspartate (NMDA) receptor antagonist originated by Novartis. Ki is 310 nM for inhibition of [3H]-CPP binding in rat brain. CGP 39551 produces excitatory effects and causes psychotomimetic effects in humans. Treatment for Craniocerebral trauma, Epilepsy and Stroke was discontinued. Uses: Craniocerebral trauma, epilepsy and stroke. Synonyms: Cgp 39551; Cgp39551; Cgp-39551; (E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester;CGP 39551;(E)-(-)-2-amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester. Grades: 98%. CAS No. 127910-32-1. Molecular formula: C8H16NO5P. Mole weight: 237.19. |  |
| Cgp 39653 | Cgp 39653 is a competitive N-Methyl-D-aspartate (NMDA) receptor antagonist. CGP 39653 can selectively bins to the NMDA receptor as an antagonist with high affinity. It is currently the ligand of choice for labeling the NMDA receptor. Uses: The ligand of choice for labeling the nmda receptor. Synonyms: Cgp 39653; Cgp-39653; Cgp-39653; (R,Z)-2-amino-4-(phosphonomethyl)hept-3-enoic acid. Grades: 98%. CAS No. 132472-31-2. Molecular formula: C8H16NO5P. Mole weight: 237.19. | |
| Cycloleucine | Cycloleucine is a competitive inhibitor of glycine modulatory site of N-methyl-D-aspartate (NMDA) receptor, with immunosuppressive, antineoplastic and cytostatic activities. It competitively inhibits methionine adenosyltransferase, thereby inhibiting S-adenosylmethionine (SAM) synthesis from methionine and ATP, and subsequent nucleic acid methylation and polyamine production. Synonyms: 1-Aminocyclopentanecarboxylic acid; 1-Amino-1-cyclopentanecarboxylic acid; 1-Amino-1-carboxycyclopentane; NSC 1026; NSC 112194; NSC 112195; NSC 112197; ACPC. Grades: ≥98%. CAS No. 52-52-8. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| DL-AP5 | DL-AP5 (2-APV) is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 shows significantly antinociceptive activity. DL-AP5 specifically blocks on channels in the rabbit retina [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-APV; DL-2-Amino-5-phosphonovaleric acid. CAS No. 76326-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100714. | |
| DL-AP5 | DL-AP5 is the racemic version of the selective N-methyl-D-aspartate (NMDA) receptor antagonist, D-AP5 (Item No. 14539).1 Whereas D-AP5 is the active (?)-stereoisomer that competitively inhibits the glutamate binding site of NMDA receptors (Kd = 1.4 μM), the (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity.1 AP5 has been widely used to study the activity of NMDA receptors particularly in regard to researching synaptic plasticity, learning, and memory.2. Group: Biochemicals. Alternative Names: 5-Phosphononorvaline; (±)-2-Amino-5-phosphonopentanoic Acid; (±)-2-Amino-5-phosphonovaleric Acid; 2-APV; 2-Amino-5-phosphonopentanoic Acid; 2-Amino-5-phosphonovaleric Acid; 5-Phosphono-DL-norvaline; AP 5; AP 5 (amino acid); APV; DL-2-Amino-5-phosphonovaleric Acid; DL-AP5. Grades: Highly Purified. CAS No. 76326-31-3. Pack Sizes: 1mg, 5mg, 10mg, 50mg. Molecular Formula: C?H??NO?P, Molecular Weight: 197.13. US Biological Life Sciences. | Worldwide |
| DL-AP5 sodium | DL-AP5 (2-APV) sodium is a competitive NMDA (N-methyl-D-aspartate) receptor antagonist. DL-AP5 sodium shows significantly antinociceptive activity. DL-AP5 sodium specifically blocks on channels in the rabbit retina [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-APV sodium; DL-2-Amino-5-phosphonovaleric acid sodium. CAS No. 1303993-72-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-100714C. | |
| Fmoc-D-serine | N-Fmoc-D-serine is an N-Fmoc-protected form of D-Serine. D-Serine is a neurotransmitter that is concentrated in the mammalian brain, and is one of the very few amino acids that occur in the D- and L-configurations in significant amounts. D-Serine is a potent agonist of the N-methyl-D-aspartate (NMDA) receptor in the brain, which is associated with schizophrenia. Use of D-Serine has been considered as an additional therapy for refractory schizophrenic patients. Synonyms: Fmoc-D-Ser-OH; Fmoc-D-β-Hydroxyalanine; (R)-Fmoc-2-amino-3-hydroxypropionic acid. Grades: ≥ 98% (HPLC). CAS No. 116861-26-8. Molecular formula: C18H17NO5. Mole weight: 327.30. | |
| γ-Glu-Glu | Gamma-L-glutamyl-L-glutamic acid is a dipeptide that plays a role in cellular metabolism. It activates N-methyl-D-aspartate (NMDA) receptors in rats. Synonyms: gamma-L-Glutamyl-L-glutamic acid; (S)-2-((S)-4-Amino-4-carboxybutanamido)pentanedioic acid; g-Glutamylglutamic acid. Grades: ≥98% by HPLC. CAS No. 1116-22-9. Molecular formula: C10H16N2O7. Mole weight: 276.24. | |
| γ-L-Glutamyl-L-glutamic Acid 1-Benzyl 21,25-Dimethyl Triester Chloride | Protected γ-L-Glutamyl-L-glutamic Acid. A short peptide found in Lentinus edodes, asparagus shoot and tabacco cells. γ-L-Glutamyl-L-glutamic Acid is a partial agonist at the N-methyl-D-aspartate receptors in cultured cerebellar granule cells. A substrate for γ-glutamyl transpeptidase (γ-GTP). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Glycylglycine (Gly-Gly, Diglycine) | N-Glycylglycine is a derivative of Glycine, a non-essential amino acid that enhances N-methyl-D-aspartate (NMDA) receptor mediated synaptic potentials in the neocortex of rats. Glycine is also being used as adjuvant therapy for the treatment of schizophrenia. Group: Biochemicals. Alternative Names: Gly-Gly, Diglycine;18: PN: WO2012015910 SEQID: 19 Unclaimed Sequence; 1: PN: WO2010117786 PAGE: 166 Claimed Protein; 2-(Aminoacetamido)acetic Acid; 221: PN: EP2161028 PAGE: 11 Claimed Protein; 31: PN: FR2860236 PAGE: 10 Claimed Protein; 36: PN: EP2204377 SEQID: 36 Claimed Protein; 36: PN: WO2010076654 SEQID: 36 Claimed Protein; 69: PN: US20110195077 SEQID: 14 Claimed Sequence; 6: PN: WO2013027191 SEQID: 14 Claimed Sequence; Diglycine; Diglycocoll; Gly2; Glycine Dipeptide; N-Glycylglycine; NSC 49346; α-Glycylglycine. Grades: Molecular Biology Grade. CAS No. 556-50-3. Pack Sizes: 100g, 250g, 500g, 1Kg, 5Kg. Molecular Formula: C?H?N?O?, Molecular Weight: 132.12. US Biological Life Sciences. | Worldwide |
| Ibotenic acid | Ibotenic acid has agonist activity at both the N-methyl-D-aspartate ( NMDA ) and trans-ACPD or metabolotropic quisqualate (Q m ) receptor sites. Uses: Scientific research. Group: Natural products. Alternative Names: (RS)-Ibotenic acid; DL-Ibotenic acid. CAS No. 2552-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2311. | |
| L-Phenylalanine | L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) ( K B of 573 μM ) and non-NMDARs , respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Phenylalanine. CAS No. 63-91-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-N0215. | |
| L-Phenylalanine-13C | L-Phenylalanine- 13 C is the 13 C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-2-Amino-3-phenylpropionic acid- 13 C. CAS No. 81201-86-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0215S2. | |
| L-Phenylalanine-13C9,15N | L-Phenylalanine- 13 C 9 , 15 N is the 13 C- and 15 N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-2-Amino-3-phenylpropionic acid- 13 C9, 15 N. CAS No. 878339-23-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0215S11. | |
| L-Phenylalanine-15N | L-Phenylalanine- 15 N is the 15 N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-2-Amino-3-phenylpropionic acid- 15 N. CAS No. 29700-34-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0215S5. | |
| L-Phenylalanine-d5 | L-Phenylalanine-d 5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 56253-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0215S12. | |
| LY 233536 | LY 233536 is a novel competitive N-methyl-D-aspartate (NMDA) receptor antagonist, but few detailed information has been published yet. Synonyms: LY 233536; LY-233536; LY233536; (3R-(3alpha,4aalpha,6beta,8aalpha))-decahydro-6-(1H-tetrazol-5-ylmethyl)- 3-Isoquinolinecarboxylic acid. Grades: 98%. CAS No. 136845-59-5. Molecular formula: C12H19N5O2. Mole weight: 265.32. | |
| LY 235959 | LY 235959 is a competitive N-Methyl-D-Aspartate Receptor antagonist originated by Eli Lilly. No development was reported for treatment of Movement disorders in USA. Research for treatment of Alzheimer's disease was discontinued. Uses: Alzheimer's disease;movement disorders. Synonyms: LY 235959; LY235959; LY-235959; (3S)-(3-alpha-4-alpha,alpha-6-beta-8-alpha,alpha)-Decahydro-6-(phosphonomethyl)-3-isoquinolinecarboxylic acid;LY 235959. Grades: 98%. CAS No. 137433-06-8. Molecular formula: C11H20NO5P. Mole weight: 277.26. | |
| N-Fmoc-D-serine | N-Fmoc-D-serine is an N-Fmoc-protected form of D-Serine (S270975). D-Serine is a neurotransmitter that is concentrated in the mammalian brain, and is one of the very few amino acids that occur in the D- and L-configurations in significant amounts. D-Serine is an potent agonist of the N-methyl-D-aspartate (NMDA) receptor in the brain, which is associated with schizophrenia. Use of D-Serine has been considered as an additional therapy for refractory schizophrenic patients. Group: Biochemicals. Grades: Highly Purified. CAS No. 116861-26-8. Pack Sizes: 1g, 5g. Molecular Formula: C18H17NO5, Molecular Weight: 327.33. US Biological Life Sciences. | Worldwide |
| PACAP (1-38) free acid | PACAP (1-38) free acid is an endogenous neuropeptide. PACAP (1-38) free acid potently stimulates antral motility and somatostatin secretion, inhibits the secretion of gastrin and stimulates the release of vasoactive intestinal polypeptide, gastrin releasing peptide and substance P. PACAP (1-38) free acid also enhances N-methyl-D-aspartate receptor function and expression of brain-derived neurotrophic factor through RACK1 [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 129405-61-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0221C. | |
| Pregn-5-en-3β-ol | Pregn-5-en-3β-ol, a steroid compound, when formulated as the biscarboxylic acid hemiesters along with androst-5-en-3β-ol, serves as a potent positive allosteric modulator of NMDA (N-methyl-D-aspartate) receptors, making it applicable for research into psychiatric disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2862-58-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W882667. | |
| Quinolinic acid | Quinolinic acid is an endogenous N-methyl-D-aspartate ( NMDA ) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 89-00-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 10 g. Product ID: HY-100807. | |
| Sarcosine | Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Methylglycine; Sarcosin. CAS No. 107-97-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-101037. | |
| Selfotel | Selfotel (CGS 19755) is a selective and competitive antagonist at N-methyl-D-aspartate (NMDA) -preferring receptor. CGS 19755 inhibits the binding of [3H]-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid to NMDA-type receptors with an IC 50 of 50 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGS 19755. CAS No. 110347-85-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15086. | |
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