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Naftifine is a topical, synthetic, broad spectrum allylamine derivate. It has antifungal, antibacterial and anti-inflammatory activity and is used for the treatment of tinea pedis, tinea cruris, and tinea corporis. It can be fungicidal or fungistatic depending on the concentration and the organisms involved. It appears to interfere with sterol biosynthesis by inhibiting the enzyme squalene 2,3-epoxidase. It was developed by Merz pharma and has been listed. Uses: Naftifine has antifungal, antibacterial and anti-inflammatory activity and is used for the treatment of tinea pedis, tinea cruris, and tinea corporis. Synonyms: Naftifinum; AW105843; AW-105843; SN105843; SN-105843; N-trans-cinnamyl-n-methyl-(1-naphthylmethyl)amine. Grades: 98%. CAS No. 65472-88-0. Molecular formula: C21H21N. Mole weight: 287.41.
Naftifine cis-Isomer
An impurity of Naftifine, which is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,5-epoxidase enzyme. Synonyms: (Z)-N-Methyl-N-(3-phenyl-2-propen-1-yl)-1-naphthalenemethanamine Hydrochloride;(Z)-N-Cinnamyl-N-methyl-1-naphthalenemethanamine Hydrochloride. Grades: > 95%. CAS No. 65473-08-7. Molecular formula: C21H21N. Mole weight: 287.41.
Naftifine hydrochloride
Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii , and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 65473-14-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B0518A.
An antifungal agent. Group: Biochemicals. Alternative Names: Exoderil, Naftin, Suadian. Grades: Highly Purified. CAS No. 65473-14-5. Pack Sizes: 50mg. US Biological Life Sciences.
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Naftifine Impurity 1
An impurity of Naftifine, which is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme. Synonyms: 1-(4-(Aminomethyl)naphthalen-1-yl)-N,N-dimethylmethanamine. Grades: > 95%. Molecular formula: C14H18N2. Mole weight: 214.31.
Naftifine-N-methyl-d3, Hydrochloride Salt
Labelled Naftifine, which is used as an antifungal agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Desmethyl Naftifine HCl
An impurity of Naftifine, which is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,4-epoxidase enzyme. Synonyms: 1-Naphthalenemethanami?ne, N-(3-phenyl-2-propenyl)?-, hydrochloride, (E)?- (9CI). Grades: > 95%. CAS No. 98978-52-0. Molecular formula: C20H19N. HCl. Mole weight: 273.38 36.46.
(E)-Naftifine
(E)-Naftifine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-Naphthalenemethanamine, N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-, 1-Naphthalenemethanamine, N-methyl-N-[(2E)-3-phenyl-2-propenyl]- (9CI), Nafetifine, N-Methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine, 1-Naphthalenemethanamine, N-methyl-N-(3-phenyl-2-propenyl)-, (E)-, Naftifine, Naftifungin. CAS No. 65472-88-0. Pack Sizes: 10MG. IUPAC Name: (E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine. Molecular Formula: C21H21N. Mole Weight: 287.40. Catalog: APS65472880. SMILES: CN(C\C=C\c1ccccc1)Cc2cccc3ccccc23. Format: Neat. Shipping: Room Temperature.
1- (4- (Aminomethyl) naphthalen-1-yl) -N, N-dimethylmethanamine is a potential impurity of Naftifine (N213100), an antimycotic allylamine. An antifungal (topical) agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C14H18N2, Molecular Weight: 214.31. US Biological Life Sciences.
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(2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne
(2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne is a byproduct in the synthesis of Terbinafine Hydrochloride (T107500); an orally active, antimycotic allylamine related to Naftifine. It is a specific inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Also antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 635708-74-6. Pack Sizes: 10mg, 100mg. Molecular Formula: C?H??Cl, Molecular Weight: 156.65. US Biological Life Sciences.
A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: E-Carboxyterbinafine, (5E) -2, 2-Dimethyl-7-[methyl (1-naphthalenylmethyl) amino]-5-hepten-3-ynoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
(E)-N-Methyl-N-(3-phenyl-2-propen-1-yl)-1-naphthalenemethanamine hydrochloride. Group: Biochemicals. Alternative Names: Naftifine hydrochloride; (E)-N-Cinnamyl-N-methyl-1-naphthalenemethanamine hydrochloride; AW 105-843. Grades: Highly Purified. CAS No. 65473-14-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C21H22ClN. US Biological Life Sciences.
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Hydroxy Terbinafine
A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: 2, 2-Dimethyl-7-[ (1-naphthalenylmethyl) amino]- (5E) -5-hepten-3-ynoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A deuterated metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-7-[(1-naphthalenyl-d7-methyl)amino]-(5E)-5-hepten-3-ynoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
A deuterated intermediate in the synthesis of the metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-7-[(1-naphthalenyl-d7-methyl)amino]-(5E)-5-hepten-3-ynoic Acid, Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Alternative Names: N- [ (2E) -6, 6-Di methyl -2-hepten-4-ynyl] -1-naphthalene methanamine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A deuterated intermediate in the synthesis of the metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
An orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Group: Biochemicals. Alternative Names: Lamisil, N- [ (2E) -6, 6-Di methyl -2-hepten-4-ynyl] -N- methyl -1-naphthalene methanamine. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
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