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6-Methoxy-2-naphthaleneaceticacid (desmethyl naproxen). Group: Biochemicals. Alternative Names: 2-(6-Methoxy-2-naphthyl)aceticacid; 6-Methoxy-2-naphthylaceticacid; 6-MNA. Grades: Highly Purified. CAS No. 23981-47-7. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C13H12O3. US Biological Life Sciences.
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6-Methoxynaphthalene-2-aceticAcid
A metabolite of Naproxen, which is a non-selective COX inhibitor. Synonyms: 2-(6-methoxy-2-naphthalenyl)aceticacid; 2-(6-methoxynaphthalen-2-yl)aceticacid. Grades: 97 %. CAS No. 23981-47-7. Molecular formula: C13H12O3. Mole weight: 216.23.
A metabolite of Nabumetone. A competitive, non-selective COX inhibitor. Group: Biochemicals. Alternative Names: 6-MNA, BRL 10720, Desmethyl Naproxen. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor (CINOD). Inhibits COX-1 and COX-2 while releasing NO. Demonstrates higher efficacy than naproxen, its congener drug, in reducing levels of profibrotic cytokine transforming growth factor-beta and oxidative stress in a mouse model of bleomycin-induced lung fibrosis. Orally available. Group: Biochemicals. Grades: Highly Purified. CAS No. 1262956-64-8. Pack Sizes: 1mg. US Biological Life Sciences.
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6-Bromo-2-napthoic Acid
6-Bromo-2-napthoic Acid is used in the preparation of Adapalene, a synthetic aromatic retinoid with specificity for RAR β and RARγ receptors. Group: Biochemicals. Alternative Names: (6-Bromonaphthalen-2-yl)aceticAcid; 6-Bromo-2-naphthalenecarboxylic Acid; 6-Bromo-2-naphthylaceticAcid. Grades: Highly Purified. CAS No. 5773-80-8. Pack Sizes: 2.5g. US Biological Life Sciences.
Setipiprant / ACT-129968 / KYTH-105 is a potent and selective CRTH2 antagonist. Setipiprant at multiple oral doses was well tolerated and reduced both the allergen-induced LAR and the associated AHR in allergic asthmatics. Group: Fluorinated apis. Alternative Names: ACT-129968. CAS No. 866460-33-5. Molecular formula: C24H19FN2O3. Mole weight: 402.43. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 2-[8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]aceticacid. Catalog: OFC866460335.
Setipiprant
Setipiprant is a potent, orally available and selective CRTH2 antagonist, which is a G protein-coupled receptor for PGD2. It may be a promising target for the treatment of allergic disorders. It was well tolerated and reduced both the allergen-induced LAR and the associated AHR in allergic asthmatics at multiple oral doses. It is a drug originally developed by Actelion, but it failed to show sufficient advantages and was discontinued from further development in this application. Later it was developed as a novel treatment for baldness by Kythera. Uses: Setipiprant may be a promising target for the treatment of allergic disorders. Synonyms: ACT-129968; ACT 129968; ACT129968; 2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)aceticacid;ACT129968;2-[8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]aceticacid;8-Fluoro-1,2,3,4-tetrahydro-2-(1-naphthalenylcarbonyl)-5H-pyrido[4,3-b]indole-5-aceticacid; KYTH-105; KYTH105; KYTH 105. Grades: >98 %. CAS No. 866460-33-5. Molecular formula: C24H19FN2O3. Mole weight: 402.42.
Tolrestat
Tolrestat is an orally active and potent aldose reductase inhibitor with IC50 value of 35 nM. It was approved for the control of certain diabetic complications. It reduces RBC (red blood cells) sorbitol levels in rats. It decreased, in dose-related manner, the RBC sorbitol levels in normal and in streptozotocin diabetic rats. It failed a Phase III trial in the U.S. due to toxicity. It was discontinued by Wyeth in 1997 because of the risk of severe liver toxicity and death. It was sold under the tradename Alredase. Uses: Tolrestat was approved for the control of certain diabetic complications. Synonyms: AY 27773; AY-27773; AY27773; Tolrestat; AY-27,773; AY 27,773; AY27,773; Alredase; Tolrestatum; Lorestat;2-[[6-methoxy-5-(trifluoromethyl)naphthalene-1-carbothioyl]-methylamino]aceticacid;N-[[6-Methoxy-5-(triiquoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglyeine. Grades: 95%. CAS No. 82964-04-3. Molecular formula: C16H14F3NO3S. Mole weight: 357.35.
1-(2,3,8,8-Tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-yl)ethanone is a volatile and highly flammable liquid that has a low boiling point, making it an ideal candidate for use in lab experiments. This compound has a distinct chemical structure that is composed of an eight-membered ring of carbon atoms and an ethanone group. Uses: 1-(2,3,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-yl)ethanone has been studied for its potential application in a variety of scientific research areas. it has been used as a reagent in the synthesis of various compounds, such as pyrrolidines, quinolines, and pyridines. it has also been used as a solvent in the extraction of various natural products, including essential oils, fatty acids. Group: Heterocyclic organic compound. Alternative Names: 7-ACETYL, 1,2,3,4,5,6,7,8-OCTAHYDRO-1,1,6,7-TETRAMETHYL NAPHTHALENE;2-ACETONAPHTHONE-1,2,3,4,5,6,7,8-OCTAHYDRO-2,3,8,8-TETRAMETHYL;1-(2,3,8,8-TETRAMETHYL-1,2,3,4,5,6,7,8-OCTAHYDRO-NAPHTHALEN-2-YL)-ETHANONE;ISOCYCLEMONE E;ISO E;ISO E SUPER;1-(1, 2, 3, 4, 5, 6, 7, 8a-octahydro-2, 3, 8, 8-tetramethyl-2-naphthalenyl)-Ethanone;1-(1, 2, 3, 4, 5, 6, 7, 8-octahydro-2, 3, 8, 8-tetramethyl-2-naphthalenyl)-e. CAS No. 54464-57-2. Molecular formula: C16H26O. Mole weight: 234.377. Appearance: Liquid. IUPACName: 1-(2,3,8,8-tetramethyl-1,3,4,5,6,7-hexahydronaphthalen-2-yl)ethanone. Canonical SMILES:
1-Acetylnaphthalene
1-Acetylnaphthalene is used in the preparation of S(-)-1-(1'-naphthyl) ethanol, an important synthetic intermediate of mevinic acid analog. Group: Biochemicals. Alternative Names: 1'-Acetonaphthone; 1-(1-Naphthalenyl)ethanone; 1-(1-Naphthyl)ethanone; 1-(Naphthalen-4-yl)ethanone; 1-Acetonaphthalene; 1-Acetonaphthone; 1-Naphthyl Methyl Ketone; Methyl 1-Naphthyl Ketone; Methyl α-Naphthyl Ketone; NSC 7659; α-Acetonaphthone; α-Acetylnaphthalene; α-Naphthyl Methyl Ketone. Grades: Highly Purified. CAS No. 941-98-0. Pack Sizes: 100g. US Biological Life Sciences.
2-[[1-[(1,4-Dimethoxy-3-methyl-2-naphthalenyl)methyl]-2-methyl-2-propen-1-yl]thio]-aceticAcid Methyl Ester is an intermediate in the synthesis of trans-2-Methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone (M294080). trans-2-Methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone is a metabollite is a metabollite of Vitamin K2, mainly MK-4 (M218595), known as a hemostatic agent and is used as adjunctive therapy for the pain of osteoporosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 99347-76-9. Pack Sizes: 5mg, 10mg. Molecular Formula: C21H26O4S, Molecular Weight: 374.49. US Biological Life Sciences.
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2-[ (1-Hydroxy-2-naphthalenyl) oxy]aceticacid
2-[ (1-Hydroxy-2-naphthalenyl) oxy]aceticacid. Group: Biochemicals. Alternative Names: [(1-Hydroxy-2-naphthyl)oxy]aceticacid. Grades: Highly Purified. CAS No. 72836-73-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C12H10O4. US Biological Life Sciences.
2-[[1-(hydroxymethyl)-2-naphthalenyl]oxy]-aceticAcid Ethyl Ester is an intermediate in the synthesis of 2-[[1-[ (Z) - (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-aceticacid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1155038-30-4. Pack Sizes: 1g, 2.5g. Molecular Formula: C15H16O4, Molecular Weight: 260.29. US Biological Life Sciences.
2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-aceticAcid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 260784-21-2. Pack Sizes: 100mg, 1g. Molecular Formula: C16H11NO4S2, Molecular Weight: 345.39. US Biological Life Sciences.
2-[[2-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-1-naphthalenyl]oxy]-aceticAcid is an analog of 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-aceticAcid (O859575). 2-[[1-[ (Z) - (4-Oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-aceticAcid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 1348775-25-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C16H11NO4S2, Molecular Weight: 345.39. US Biological Life Sciences.
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2-[ (3-Hydroxy-2-naphthalenyl) oxy]aceticacid
2-[ (3-Hydroxy-2-naphthalenyl) oxy]aceticacid. Group: Biochemicals. Alternative Names: (3-Hydroxy-2-naphthyloxy)aceticacid; [ (3-Hydroxy-2-naphthalenyl) oxy]aceticacid. Grades: Highly Purified. CAS No. 72836-74-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C12H10O4. US Biological Life Sciences.
2-[[4-(1-Naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-aceticAcid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1038366-57-2. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H11N3O2S, Molecular Weight: 285.32. US Biological Life Sciences.
2-[[5-Bromo-4-(1-cyclopropyl-2-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-aceticAcid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-94-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H14BrN3O2S, Molecular Weight: 404.28. US Biological Life Sciences.
2-[[5-Bromo-4-(4-propyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-aceticAcid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-96-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C17H16BrN3O2S, Molecular Weight: 406.3. US Biological Life Sciences.
2-[[5-Bromo-4-(5-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-aceticAcid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1533519-97-9. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H14BrN3O2S, Molecular Weight: 404.28. US Biological Life Sciences.
2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-aceticAcid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. Group: Biochemicals. Grades: Highly Purified. CAS No. 1210330-64-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H10BrN3O2S, Molecular Weight: 364.22. US Biological Life Sciences.
2-[[6-bromo-1-[ (4-oxo-2-thioxo-5-thiazolidinylidene) methyl]-2-naphthalenyl]oxy]-aceticAcid is used in biological activities in the preparation and aldose reductase inhibitory activity of a new series of 5-[[2- (ω -carboxyalkoxy) aryl]methylene]-4-oxo-2-thioxothiazolidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 123021-42-1. Pack Sizes: 50mg, 500mg. Molecular Formula: C16H10BrNO4S2, Molecular Weight: 424.29. US Biological Life Sciences.
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2-[ (6-Hydroxy-2-naphthalenyl) oxy]aceticacid
2-[ (6-Hydroxy-2-naphthalenyl) oxy]aceticacid. Group: Biochemicals. Alternative Names: [ (6-Hydroxy-2-naphthalenyl) oxy]aceticacid. Grades: Highly Purified. CAS No. 10441-36-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C12H10O4. US Biological Life Sciences.
Used in the preparation of Amrubicin, an anthracycline antibiotic. Group: Biochemicals. Alternative Names: 2-(Acetylamino)-1,2,3,4-tetrahydro-5,8-dimethoxy-2-naphthalenecarboxylic Acid-13C. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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2-(Naphthalen-2-yl)aceticacid
2-(Naphthalen-2-yl)aceticacid (2-Naphthylaceticacid), a plant growth regulator, is a 3-Indoleaceticacid (HY-18569) antagonist [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 2-Naphthylaceticacid. CAS No. 581-96-4. Pack Sizes: 5 g; 25 g. Product ID: HY-W016187.
2-Naphthyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a biomedicine product used in the treatment of various diseases. It exhibits potential as an antineoplastic agent and has shown inhibitory effects on tumor growth. This compound plays a crucial role in cancer research and drug development, specifically targeting malignancies related to the glucosamine pathway. Synonyms: [(2R,3S,4R,5R,6S)-5-acetamido-3,4-diacetyloxy-6-naphthalen-2-yloxyoxan-2-yl]methyl acetate; (2/'NAPHTHYL) 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSIDE; beta-D-Glucopyranoside, 2-naphthalenyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate; Naphthalen-2-yl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucopyranoside; aceticacid 3-acetoxy-2-acetoxymethyl-5-acetylamino-6-(naphthalen-2-yloxy)-tetrahydro-pyran-4-yl ester. CAS No. 131531-80-1. Molecular formula: C24H27NO9. Mole weight: 473.47.
6-(3-((1r,3s,5R,7S)-3-Acetoxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoic Acid Ethyl Ester is an impurity of Adapalene, which is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne. Synonyms: 2-Naphthalenecarboxylic acid, 6-[3-[(5R,7S)-3-(acetyloxy)tricyclo[3.3.1.13,7]dec-1-yl]-4-methoxyphenyl]-, ethyl ester. Molecular formula: C32H34O5. Mole weight: 498.61.
Acetyl-3-(2-naphthyl)-D-alanine was used to study the aromatic binding site of α-chymotrypsin. It was used to design an asymmetric synthesis of a new cylindrically chiral and air-stable ferrocenyldiphosphine and its application to rhodium-catalyzed asymmetric hydrogenation. Synonyms: Ac-D-Ala(2-naphthyl)-OH; (R)-N-Acetyl-2-naphthylalanine; Ac-D-2-Nal-OH; (R)-2-ACETAMIDO-3-(NAPHTHALEN-2-YL)PROPANOIC ACID; N-Acetyl-3-(2-naphthyl)-D-alanine; 2-Naphthalenepropanoic acid, a-(acetylamino)-, (aR)-; Ac-D-Ala(2-Naph)-OH. Grades: ≥ 98% (HPLC). CAS No. 37440-01-0. Molecular formula: C15H15NO3. Mole weight: 257.28.
Acid Red 1
Acid Red 1. Group: Biochemicals. Alternative Names: 1379 Red; Acetyl Red G; Acetyl Red J; Acetyl Rose 2GL; Acid Bright Red; Acid Brilliant Fuchsine 2G; Acid Brilliant Red; Acid Fast Red 3G; Acid Fast Red EG; Acid Fast Red EGG; Acid Geranine 2G; Acid Geranine 2GN; Acid Leather Red KG; Acid Naftol Red G; Acid Naphthol Red G; Acid Phloxine GA; Acid Red 1; Acid Red 2G; Acid Red G; Acid Red GA; Acid Red GN; Acid Red Geramine G; Acid Rose 2GL; Acidal Brilliant Red 2G; Acidine Red G; Acilan Naphthol Red G; Ahcocid Carmine 2G; Amacid Phloxine G; Amacid Phloxine G Conc; Amecid Floxine 2GN; Amido Naphthol Red 2G; Amido Naphthol Red G; Amido Naphthol Red GA; Amido Red 2G; Atul Acid Geranine G; Azo...iton Red G; Leather Red G; Lignin Pink; Lissamine Red 2G; Monacid Red 2G; Multacid Red G; Multicuer Red G; Naphthazine Rose 2G; Naphtocard Red 2G; Neolan Red E 2GN; Phloxine 2G; Phloxine G; Pontacyl Carmine 2G; Ravi Acid Red AG; Red 2G; Ritacid Red S; Sandolan Rhodine E 2GL; Sandolan Rhodine E 2GLI; Solar Fast Red 3G; Triacid Amidonaphthol Red G; Triacid Light Red G; Unitertracid Red 2G; Vibra Color Red ARE 1; Vondacid Light Red NG; Water Red 177614; 5-(Acetylamino)-4-hydroxy-3-(2-phenyldiazenyl)-2,7-naphthalenedisulfonic Acid Sodium Salt. Grades: Highly Purified. CAS No. 3734-67-6. Pack Sizes: 5g. Molecular Formula: C18H13N3NaO8S2, Molecular Weight: 509.42. US Biological Life Sciences.
Agomelatine L(+)-Tartaric acid is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. It is used as an antidepressant drug. It has been approved by FDA in October 2011. It has toxicities, such as Hyperhidrosis, Abdominal pain, Nausea, Vomiting, Diarrhoea, Constipation, Back pain, Fatigue and so on. Uses: Agomelatine l(+)-tartaric acid is used as an antidepressant drug. Synonyms: Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-,(2R,3R)-2,3-dihydroxybutanedioate;S-20098 L(+)-Tartaric acid. Grades: >98%. CAS No. 824393-18-2. Molecular formula: C19H23NO8. Mole weight: 393.39.
Amino-naphthalen-1-yl-aceticacid
Amino-naphthalen-1-yl-aceticacid. Group: Biochemicals. Alternative Names: 2-Amino-2-(naphthalen-4-yl)aceticacid. Grades: Highly Purified. CAS No. 97611-60-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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Amino-naphthalen-1-yl-aceticacid ≥95% (NMR)
Amino-naphthalen-1-yl-aceticacid ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Amino(naphthalen-2-yl)aceticacid
Amino(naphthalen-2-yl)aceticacid. Group: Biochemicals. Grades: Highly Purified. CAS No. 33741-78-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Black PN. Group: Biochemicals. Alternative Names: 4-(Acetylamino)-5-hydroxy-6-[2-[7-sulfo-4-[2-(4-sulfophenyl)diazenyl]-1-naphthalenyl]diazenyl]-1,7-naphthalenedisulfonic Acid Sodium Salt (1:4); 4-(Acetylamino)-5-hydroxy-6-[[7-sulfo-4-[(4-sulfophenyl)azo]-1-naphthalenyl]azo]-, tetrasodium Salt 1,7-Naphthalenedisulfonic Acid; Brilliant Black BN; C.I. Food Black 1; 1743 Black; Black PN; Blue Black BN; Brilliant Acid Black BN Extra Pure A; Brilliant Acid Black BNA Export; Brilliant Black 1; Brilliant Black 80; Brilliant Black A; Brilliant Black N; Brilliant Black NAF; Brilliant Black NFQ; Brilliant Black PN; C.I. 28440; Certicol Black PNW; Cilefa Black B; E 151; Edicol Supra Black BN; Food Black 1; Hexacol Black PN; L Black 8000; Melan Black; Tetrasodium 2-[4-(p-Sulfophenylazo)-7-sulfo-1-naphthylazo]-8-acetamido-1-naphthol-3,5-disulfonate; Xylene Black F. Grades: Highly Purified. CAS No. 2519-30-4. Pack Sizes: 1g, 10g, 100g, 250g. Molecular Formula: C28H17N5Na4O14S4, Molecular Weight: 867.68. US Biological Life Sciences.
Worldwide
BMS 961
BMS 961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist with an IC50 value of 30 nM. Synonyms: BMS961; BMS-961; 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino]-benzoic acid; Benzoic acid, 3-fluoro-4-[[2-hydroxy-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)acetyl]amino]-. Grades: ≥97% by HPLC. CAS No. 185629-22-5. Molecular formula: C23H26FNO4. Mole weight: 399.45.
Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist. It decreases tumor volume of Dunning R3327H prostate tumor flank implants in rats when administered at a dose of 1 mg/kg per month. Formulations containing degarelix have been used in the treatment of advanced prostate cancer. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-4-((S)-dihydroorotamido)-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide aceticacid; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate (1:1); FE 200486; Gonax. Grades: ≥98%. CAS No. 934016-19-0. Molecular formula: C82H103ClN18O16.C2H4O2. Mole weight: 1692.31.
Des-Amido-Cetrorelix
Des-Amido-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Alanine; Cetrorelix Acid; Cetrorelix impurity-7+OH; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alanine; ((S)-2-((S)-2-((R)-2-((S)-2-((S)-2-((R)-2-((R)-2-((R)-2-acetamido-3-(naphthalen-2-yl)propanamido)-3-(4-chlorophenyl)propanamido)-3-(pyridin-3-yl)propanamido)-3-hydroxypropanamido)-3-(4-hydroxyphenyl)propanamido)-5-ureidopentanamido)-4-methylpentanamido)-5-((diaminomethylene)amino)pentanoyl)-L-prolyl-D-alanine. CAS No. 2901757-74-0. Molecular formula: C70H91ClN16O15. Mole weight: 1432.05.
Des-D-Ala-Cetrorelix
Des-D-Ala-Cetrorelix is an impurity of Cetrorelix, which is a gonadotropin-releasing hormone antagonist used in the treatment of prostate and breast cancers. Synonyms: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Proline; 1-9 Acid Cetrorelix; ((S)-2-((S)-2-((R)-2-((S)-2-((S)-2-((R)-2-((R)-2-((R)-2-acetamido-3-(naphthalen-2-yl)propanamido)-3-(4-chlorophenyl)propanamido)-3-(pyridin-3-yl)propanamido)-3-hydroxypropanamido)-3-(4-hydroxyphenyl)propanamido)-5-ureidopentanamido)-4-methylpentanamido)-5-((diaminomethylene)amino)pentanoyl)-L-proline; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-proline. CAS No. 2901757-75-1. Molecular formula: C67H86ClN15O14. Mole weight: 1360.97.
Catalyst system that exhibits very high catalytic activity and enantioselectivity in the hydrogenation of a wide range of substrates. Catalyst used in the synthesis of β-amino acids by hydrogenation. Group: Ruthenium series catalysts. Alternative Names: Bis(acetato)(binap) ruthenium; Diacetato[(R)-(+)-2,2 inverted exclamation marka-bis(diphenylphosphino)-1,1 inverted exclamation marka-binaphthyl]ruthenium(II); Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II), Ru(OAc)2[(R)-binap]; DIACETATO[(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II); RU(OAC)2[(R)-BINAP]; DIACETATO[(S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL]RUTHENIUM(II); Diacetato[(S)-(-)-2,2 inverted exclamation marka-bis(diphenylphosphino)-1,1 inverted exclamation marka-binaphthyl]ruthenium(II); SC10141; 325146-81-4. CAS No. 325146-81-4. Molecular formula: C48H40O4P2Ru. Mole weight: 843.862g/mol. IUPACName: aceticacid;[1-(2-diphenylphosphanylnaphthalen-1-yl)naphthalen-2-yl]-diphenylphosphane;ruthenium. Canonical SMILES: CC (=O)O. CC (=O)O. C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=C (C4=CC=CC=C4C=C3)C5=C (C=CC6=CC=CC=C65)P (C7=CC=CC=C7)C8=CC=CC=C8. [Ru]. Catalog: ACM325146814.