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| Product | Description | |
|---|---|---|
| Nebivolol Impurity 1 | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.19 nM. Synonyms: (R,R,S,S)-Nebivolol; (αR,α'S,2R,2'S)-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol; (R)-1-((R)-6-Fluorochroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol. Grades: > 95%. CAS No. 1360598-84-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 405.45. |  |
| Nebivolol Impurity 10 HCl (RS,SR) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.31 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'S,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-23-6. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91. | |
| Nebivolol Impurity 11 | Nebivolol Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-azanediylbis(1-(6-fluorochroman-2-yl)ethan-1-ol). CAS No. 99200-09-6. Molecular Formula: C22H25F2NO4. Mole Weight: 405.18. Catalog: APB99200096. |  |
| Nebivolol Impurity 11 (D-Nebivolol) HCl | Nebivolol Impurity 11 (D-Nebivolol) HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 213132-06-0. Molecular Formula: C22H26ClF2NO4. Mole Weight: 441.9. Catalog: APB213132060. | |
| Nebivolol Impurity 11 (SR,SR) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.32 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'R,?2S,?2'R)?-. Grades: > 95%. Molecular formula: C22H25F2NO4. Mole weight: 405.45. | |
| Nebivolol Impurity 12 | Nebivolol Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 920275-27-0. Molecular Formula: C22H26ClF2NO4. Mole Weight: 441.9. Catalog: APB920275270. | |
| Nebivolol Impurity 12 HCl (RR,RR) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.33 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-25-8. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91. | |
| Nebivolol Impurity 13 | Nebivolol Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 920275-25-8. Molecular Formula: C22H26ClF2NO4. Mole Weight: 441.9. Catalog: APB920275258. | |
| Nebivolol Impurity 13 HCl (SS,SS) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.34 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'S,?2S,?2'S)?-. Grades: > 95%. CAS No. 920275-27-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91. | |
| Nebivolol Impurity 14 | Nebivolol Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C11H12ClFO2. Mole Weight: 230.66. Catalog: APB08798. | |
| Nebivolol Impurity 14 (D-Nebivolol) (SR,RR) HCl | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.35 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2R,?2'S)?-. Grades: > 95%. CAS No. 213132-06-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91. | |
| Nebivolol Impurity 15 | Nebivolol Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1315508-93-0. Molecular Formula: C11H12ClFO2. Mole Weight: 230.66. Catalog: APB1315508930. | |
| Nebivolol Impurity 16 | Nebivolol Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1315508-96-3. Molecular Formula: C11H12ClFO2. Mole Weight: 230.66. Catalog: APB1315508963. | |
| Nebivolol Impurity 17 | Nebivolol Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1315508-95-2. Molecular Formula: C11H12ClFO2. Mole Weight: 230.66. Catalog: APB1315508952. | |
| Nebivolol Impurity 18 | Nebivolol Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1315508-94-1. Molecular Formula: C11H12ClFO2. Mole Weight: 230.66. Catalog: APB1315508941. | |
| Nebivolol Impurity 1 (RR,SS) | Nebivolol Impurity 1 (RR,SS). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-1-((R)-6-fluorochroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol. CAS No. 1360598-84-0. Molecular Formula: C22H25F2NO4. Mole Weight: 405.44. Catalog: APB1360598840. | |
| Nebivolol Impurity 2 | Nebivolol Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S,1R,1'R)-2,2'-azanediylbis(1-((S)-6-fluorochroman-2-yl)ethanol). CAS No. 920275-19-0. Molecular Formula: C22H25F2NO4. Mole Weight: 405.44. Catalog: APB920275190. | |
| Nebivolol Impurity 20 | Nebivolol Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-1-((R)-6-fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol. CAS No. 2415933-03-6. Molecular Formula: C22H25F2NO4. Mole Weight: 405.44. Catalog: APB2415933036. | |
| Nebivolol Impurity 20 | Nebivolol Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C31H33F2NO8. Mole Weight: 585.6. Catalog: APB08799. | |
| Nebivolol Impurity 21 | Nebivolol Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391051-68-5. Molecular Formula: C22H24F2N2O5. Mole Weight: 434.44. Catalog: APB1391051685. | |
| Nebivolol Impurity 22 | Nebivolol Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 876514-31-7. Molecular Formula: C11H11FO2. Mole Weight: 194.21. Catalog: APB876514317. | |
| Nebivolol Impurity 26 | Nebivolol Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (RS)-1-((RS)-6-fluorochroman-2-yl)-2-(methylamino)ethanol. Molecular Formula: C12H16FNO2. Mole Weight: 225.12. Catalog: APB01461. | |
| Nebivolol Impurity 27 (Hydrochloride) | Nebivolol Impurity 27 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-(benzylazanediyl)bis(1-(6-fluorochroman-2-yl)ethanol) hydrochloride. CAS No. 1803397-45-6. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB1803397456. | |
| Nebivolol Impurity 28 | Nebivolol Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-6-fluoro-2-((S)-oxiran-2-yl)chroman. CAS No. 129050-23-3. Molecular Formula: C11H11FO2. Mole Weight: 194.07. Catalog: APB129050233. | |
| Nebivolol Impurity 29 | Nebivolol Impurity 29. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-6-fluoro-2-((R)-oxiran-2-yl)chroman. CAS No. 197706-50-6. Molecular Formula: C11H11FO2. Mole Weight: 194.07. Catalog: APB197706506. | |
| Nebivolol Impurity 2 HCl (SR,RS) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.20 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2S,?2'S)?-. Grades: > 95%. CAS No. 920275-19-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91. | |
| Nebivolol Impurity 3 | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.24 nM. Synonyms: 2H-1-Benzopyran-2-methanol, 6-fluoro-3,?4-dihydro-α-[[(phenylmethyl)?amino]?methyl]?-, (αR,?2R)?-. Grades: > 95%. CAS No. 1029684-20-5. Molecular formula: C17H18FNO2. Mole weight: 287.34. | |
| Nebivolol Impurity 30 | Nebivolol Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-6-fluoro-2-((S)-oxiran-2-yl)chroman. CAS No. 129050-26-6. Molecular Formula: C11H11FO2. Mole Weight: 194.07. Catalog: APB129050266. | |
| Nebivolol Impurity 31 | Nebivolol Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-6-fluoro-2-((R)-oxiran-2-yl)chroman. CAS No. 197706-51-7. Molecular Formula: C11H11FO2. Mole Weight: 194.20. Catalog: APB197706517. | |
| Nebivolol Impurity 33 | Nebivolol Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-6-fluorochroman-2-carboxylic acid. CAS No. 129101-37-7. Molecular Formula: C10H9FO3. Mole Weight: 196.18. Catalog: APB129101377. | |
| Nebivolol Impurity 34 | Nebivolol Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-6-fluorochroman-2-carboxylic acid. CAS No. 129101-36-6. Molecular Formula: C10H9FO3. Mole Weight: 196.18. Catalog: APB129101366. | |
| Nebivolol Impurity 35 | Nebivolol Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-methyl 6-fluorochroman-2-carboxylate. CAS No. 129050-25-5. Molecular Formula: C11H11FO3. Mole Weight: 210.20. Catalog: APB129050255. | |
| Nebivolol Impurity 36 | Nebivolol Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-methyl 6-fluorochroman-2-carboxylate. CAS No. 1219915-01-1. Molecular Formula: C11H11FO3. Mole Weight: 210.20. Catalog: APB1219915011. | |
| Nebivolol Impurity 37 | Nebivolol Impurity 37. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-ethyl 6-fluorochroman-2-carboxylate. CAS No. 1335103-88-2. Molecular Formula: C12H13FO3. Mole Weight: 224.23. Catalog: APB1335103882. | |
| Nebivolol Impurity 38 | Nebivolol Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-ethyl 6-fluorochroman-2-carboxylate. CAS No. 1335103-90-6. Molecular Formula: C12H13FO3. Mole Weight: 224.23. Catalog: APB1335103906. | |
| Nebivolol Impurity 39 | Nebivolol Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-chloro-1-(6-fluorochroman-2-yl)ethanone. CAS No. 1219914-99-4. Molecular Formula: C11H10ClFO2. Mole Weight: 228.65. Catalog: APB1219914994. | |
| Nebivolol Impurity 4 | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.25 nM. Synonyms: 2H-1-Benzopyran-2-methanol, 6-fluoro-3,?4-dihydro-α-[[(phenylmethyl)?amino]?methyl]?-, (αS,?2S)?-. Grades: > 95%. CAS No. 129050-29-9. Molecular formula: C17H18FNO2. Mole weight: 287.34. | |
| Nebivolol Impurity 40 | Nebivolol Impurity 40. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-chloro-1-(6-fluorochroman-2-yl)ethanone. CAS No. 1219915-00-0. Molecular Formula: C11H10ClFO2. Mole Weight: 228.65. Catalog: APB1219915000. | |
| Nebivolol Impurity 47 | Nebivolol Impurity 47. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-(benzylamino)-1-((S)-6-fluorochroman-2-yl)ethanol. CAS No. 1030385-16-0. Molecular Formula: C18H20FNO2. Mole Weight: 301.36. Catalog: APB1030385160. | |
| Nebivolol Impurity 49 (Hydrochloride) | Nebivolol Impurity 49 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(benzyl((S)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01460. | |
| Nebivolol Impurity 5 | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.26 nM. Synonyms: 2H-1-Benzopyran-2-methanol, 6-fluoro-3,?4-dihydro-α-[[(phenylmethyl)?amino]?methyl]?-. Grades: > 95%. CAS No. 99199-91-4. Molecular formula: C17H18FNO2. Mole weight: 287.34. | |
| Nebivolol Impurity 50 (Hydrochloride) | Nebivolol Impurity 50 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(benzyl((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01459. | |
| Nebivolol Impurity 51 (Hydrochloride) | Nebivolol Impurity 51 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(benzyl((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((R)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01458. | |
| Nebivolol Impurity 52 (Hydrochloride) | Nebivolol Impurity 52 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-(benzyl((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01457. | |
| Nebivolol Impurity 58 | Nebivolol Impurity 58. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 6-fluorochroman-2-carboxylate. Molecular Formula: C12H13FO3. Mole Weight: 224.23. Catalog: APB01456. | |
| Nebivolol Impurity 59 | Nebivolol Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 6-fluorochroman-2-carboxylate. Molecular Formula: C11H11FO3. Mole Weight: 210.20. Catalog: APB01453. | |
| Nebivolol Impurity 60 | Nebivolol Impurity 60. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Nebivolol Impurity 60. Molecular Formula: C13H15FO3S. Mole Weight: 270.32. Catalog: APB01454. | |
| Nebivolol Impurity 61 | Nebivolol Impurity 61. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Nebivolol Impurity 61. Molecular Formula: C13H15FO3S. Mole Weight: 270.32. Catalog: APB01455. | |
| Nebivolol Impurity 62 | Nebivolol Impurity 62. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-1-(6-fluorochroman-2-yl)ethanone. Molecular Formula: C11H10ClFO2. Mole Weight: 228.65. Catalog: APB01451. | |
| Nebivolol Impurity 63 | Nebivolol Impurity 63. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Nebivolol Impurity 63. Molecular Formula: C14H17FO3S. Mole Weight: 284.35. Catalog: APB01452. | |
| Nebivolol Impurity 64 | Nebivolol Impurity 64. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-1-(6-fluorochroman-2-yl)ethanol. Molecular Formula: C11H12ClFO2. Mole Weight: 230.66. Catalog: APB01450. | |
| Nebivolol Impurity 65 | Nebivolol Impurity 65. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Nebivolol Impurity 65. Molecular Formula: C13H15FO3S. Mole Weight: 270.32. Catalog: APB01449. | |
| Nebivolol Impurity 67 | Nebivolol Impurity 67. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (RS)-6-fluoro-2-((SR)-oxiran-2-yl)chroman. Molecular Formula: C11H11FO2. Mole Weight: 194.20. Catalog: APB01448. | |
| Nebivolol Impurity 69 | Nebivolol Impurity 69. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-1-((S)-6-fluorochroman-2-yl)ethanol. Molecular Formula: C11H12ClFO2. Mole Weight: 230.66. Catalog: APB01446. | |
| Nebivolol Impurity 6 (SS) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.27 nM. Synonyms: (S)-(benzylamino)((S)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.26. | |
| Nebivolol Impurity 70 | Nebivolol Impurity 70. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-1-((R)-6-fluorochroman-2-yl)ethanol. Molecular Formula: C11H12ClFO2. Mole Weight: 230.66. Catalog: APB01447. | |
| Nebivolol Impurity 71 | Nebivolol Impurity 71. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R)-6-fluoro-2-(oxiran-2-yl)chroman. Molecular Formula: C11H11FO2. Mole Weight: 194.20. Catalog: APB01445. | |
| Nebivolol Impurity 72 (Hydrochloride) | Nebivolol Impurity 72 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(benzyl((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01444. | |
| Nebivolol Impurity 74 | Nebivolol Impurity 74. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (SR)-1-((RS)-6-fluorochroman-2-yl)-2-(methylamino)ethanol. Molecular Formula: C12H16FNO2. Mole Weight: 225.26. Catalog: APB01443. | |
| Nebivolol Impurity 75 | Nebivolol Impurity 75. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(benzylamino)-1-(6-fluorochroman-2-yl)ethanol. CAS No. 99199-91-4. Molecular Formula: C18H20FNO2. Mole Weight: 301.36. Catalog: APB99199914. | |
| Nebivolol Impurity 76 | Nebivolol Impurity 76. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (SR)-2-(benzylamino)-1-((RS)-6-fluorochroman-2-yl)ethanol. Molecular Formula: C18H20FNO2. Mole Weight: 301.36. Catalog: APB01442. | |
| Nebivolol Impurity 77 | Nebivolol Impurity 77. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (RS)-2-(benzylamino)-1-((RS)-6-fluorochroman-2-yl)ethanol. Molecular Formula: C18H20FNO2. Mole Weight: 301.36. Catalog: APB01441. | |
| Nebivolol Impurity 7 (RR) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.28 nM. Synonyms: (R)-(benzylamino)((R)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.27. | |
| Nebivolol Impurity 81 (Hydrochloride) | Nebivolol Impurity 81 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S,1R,1'R)-2,2'-(benzylazanediyl)bis(1-((S)-6-fluorochroman-2-yl)ethanol) hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01440. | |
| Nebivolol Impurity 8 (SR) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.29 nM. Synonyms: (S)-(benzylamino)((R)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.27. | |
| Nebivolol Impurity 9 (RS) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.30 nM. Synonyms: (R)-(benzylamino)((S)-chroman-2-yl)methanol. Grades: > 95%. Molecular formula: C12H16FNO2. Mole weight: 225.27. | |
| Nebivolol Impurity A | This active molecular is a β-adrenergic receptor antagonist. Levonebivolol is an enantiomer of Nebivolol which is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and left ventricular failure in Europe. It is highly cardioselective under certain circumstances. In Apr 2015, US FDA approved an ANDA for nebivolol submitted by Amerigen. In Jan 2016, Forest Laboratories and the University of Chicago withdrew a phase II/III trial for Hypertension in patients with chronic obstructive pulmonary disease in USA. Uses: Treatment of hypertension and left ventricular failure. Synonyms: R67145; R-67145; R 67145; Levonebivolol. (αS,α'S,2R,2'S)-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; [2S-[2R*[R*[R*(S*)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro- 2H-1-benzopyran-2-methanol; Levonebivolol; R 67145; l-Nebivolol. Grades: 98%. CAS No. 118457-16-2. Molecular formula: C22H25F2NO4. Mole weight: 405.44. | |
| Nebivolol Impurity B (SR,SS) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.17 nM. Synonyms: [2S-[2R*[R*[S*(R*)]]]]-α,α'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol. Grades: > 95%. CAS No. 119365-25-2. Molecular formula: C22H25F2NO4. Mole weight: 405.45. | |
| Nebivolol Impurity I HCl (RR,SR) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.21 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'S,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-20-3. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91. | |
| Nebivolol Impurity II HCl (SS,RS) | An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.22 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'S,?2S,?2'S)?-. Grades: > 95%. CAS No. 920299-27-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91. | |
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