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| Product | Description | |
|---|---|---|
| Neurokinin A | Neurokinin A is a member of the endogenous tachykinin agonist with preference for the NK-2R (NK-2 receptor). Synonyms: Neurokinin A; Substance K; Neuromedin L; H-D-His-D-Lys-Thr-Asp-D-Ser-Phe-D-Val-Gly-D-Leu-D-Met-NH2. Grades: ≥97% by HPLC. CAS No. 86933-74-6. Molecular formula: C50H80N14O14S. Mole weight: 1133.33. |  |
| Neurokinin A | Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Substance K; Neurokinin α; Neuromedin L. CAS No. 86933-74-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0197. |  |
| Neurokinin A (4-10) | Neurokinin A (4-10), an endogenous neuromodulatory peptide formerly known as substance K, is an atachykinin NK2 receptor agonist. Synonyms: H-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2; L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; (5S,8S,14S,17S,20S,23S)-23-amino-17-benzyl-5-carbamoyl-20-(hydroxymethyl)-8-isobutyl-14-isopropyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid. Grades: 98%. CAS No. 97559-35-8. Molecular formula: C34H54N8O10S. Mole weight: 766.91. | |
| Neurokinin A TFA | Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Substance K TFA; Neurokinin α TFA; Neuromedin L TFA; NKA TFA. CAS No. 2828433-19-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0197A. | |
| Neurokinin B | Neurokinin B, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Uses: Neurotransmitter agents. Synonyms: NKB; H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; Neurokinin K; Neurokinin beta; β-Neurokinin; Neuromedin K; (5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidazol-4-yl)methyl)-32-amino-17,20-dibenzyl-5-carbamoyl-23-(carboxymethyl)-8-isobutyl-14-isopropyl-29-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-2-thia-6,9,12,15,18,21,24,27,30-nonaazatetratriacontan-34-oic acid. Grades: ≥95%. CAS No. 86933-75-7. Molecular formula: C55H79N13O14S2. Mole weight: 1210.42. | |
| Neurokinin B acetate | Neurokinin B acetate, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Synonyms: H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2.CH3CO2H; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide acetic acid; Neurokinin B (swine spinal cord) acetate; Neurokinin B (human) acetate; Neurokinin B (pig spinal cord) acetate; Neurokinin B (porcine) acetate; Neurokinin β (pig spinal cord) acetate; Neuromedin K (pig spinal cord) acetate; Porcine neurokinin B acetate; Zneurok1 (human) acetate. Grades: ≥95%. Molecular formula: C57H83N13O16S2. Mole weight: 1270.48. | |
| Neurokinin B TFA | Neurokinin B TFA belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect [1]. Uses: Scientific research. Group: Peptides. CAS No. 101536-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0242A. | |
| [Ala5, beta-Ala8]-Neurokinin A (4-10) | It is a potent and selective agonist of NK-2 receptor. Synonyms: L-alpha-aspartyl-L-alanyl-L-phenylalanyl-L-valyl-beta-alanyl-L-leucyl-L-methioninamide; L-Methioninamide, L-α-aspartyl-L-alanyl-L-phenylalanyl-L-valyl-β-alanyl-L-leucyl-; (5S,8S,15S,18S,21S,24S)-24-Amino-18-benzyl-5-carbamoyl-8-isobutyl-15-isopropyl-21-methyl-7,10,14,17,20,23-hexaoxo-2-thia-6,9,13,16,19,22-hexaazahexacosan-26-oic acid; Asp-Ala-Phe-Val-β-Ala-Leu-Met-NH2; [ala5,β-ala8]-α-neurokinin fragment 4-10. Grades: ≥95%. CAS No. 127633-71-0. Molecular formula: C35H56N8O9S. Mole weight: 764.93. | |
| [bAla8]-Neurokinin A (4-10) | An agonist of neurokinin 2 (NK2) receptor. Synonyms: MEN 10210; H-Asp-Ser-Phe-Val-bAla-Leu-Met-NH2; DSFVXLM; L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-beta-alanyl-L-leucyl-L-methioninamide. Grades: ≥95%. CAS No. 122063-01-8. Molecular formula: C35H56N8O10S. Mole weight: 780.93. | |
| [bAla8]-Neurokinin A(4-10) | [bAla8]-Neurokinin A(4-10). Group: Biochemicals. Grades: Purified. CAS No. 122063-01-8. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| (d-Pro2,d-trp6,8,nle10)-neurokinin b | Heterocyclic Organic Compound. Alternative Names: ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2;(D-PRO2,D-TRP6,8,NLE10)-NEUROKININ B;DPHDFWVWL-NLE-NH2;H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2. CAS No. 109212-72-8. Molecular formula: C67H87N15O14. Mole weight: 1326.5. Catalog: ACM109212728. |  |
| [Lys5,?MeLeu9,?Nle10]?-?Neurokinin A (4-10) Fragment | [Lys5,MeLeu9,Nle10]-Neurokinin A (4-10) Fragment is a neurokinin A derivative. It is an NK2 agonist with IC50 value of 6.1 nM. It can induce contraction in smooth muscle cells of rodents. Synonyms: (3S,6S,9S,12S,18S,21S)-3-Amino-6-(4-aminobutyl)-9-benzyl-21-carbamoyl-18-isobutyl-12-isopropyl-17-methyl-4,7,10,13,16,19-hexaoxo-5,8,11,14,17,20-hexaazapentacosan-1-oic acid. Grades: ≥95% by HPLC. CAS No. 137565-28-7. Molecular formula: C39H65N9O9. Mole weight: 804. | |
| (Nle10)-neurokinin a(4-10) | Heterocyclic Organic Compound. CAS No. 110863-33-7. Molecular formula: C35H56N8O10. Catalog: ACM110863337. | |
| (N-Me-phe7)-neurokinin b | Heterocyclic Organic Compound. CAS No. 110880-53-0. Molecular formula: C60H81N13O14S2. Purity: 0.96. Catalog: ACM110880530. | |
| (N-Me-Phe7)-Neurokinin B | The MePhe-analog of NKB shows high selectivity for NKB receptors. Synonyms: (MePhe7)neurokinin B; L-α-Aspartyl-L-methionyl-L-histidyl-L-α-aspartyl-L-phenylalanyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide. Grades: 95%. CAS No. 110880-53-0. Molecular formula: C60H81N13O14S2. Mole weight: 1272.49. | |
| (Pro7)-neurokinin b | Heterocyclic Organic Compound. Alternative Names: ASP-MET-HIS-ASP-PHE-PHE-PRO-GLY-LEU-MET-NH2;H2N-ASP-MET-HIS-ASP-PHE-PHE-PRO-GLY-LEU-MET-NH2;H-ASP-MET-HIS-ASP-PHE-PHE-PRO-GLY-LEU-MET-NH2;(PRO7)-NEUROKININ B;L-Asp-L-Met-L-His-L-Asp-L-Phe-L-Phe-L-Pro-Gly-L-Leu-L-Met-NH2. CAS No. 120814-48-4. Molecular formula: C55H77N13O14S2. Mole weight: 1208.41. Catalog: ACM120814484. | |
| (Trp7,β-Ala8)-Neurokinin A (4-10) | (Trp7,β-Ala8)-Neurokinin A (4-10) is a potent and selective NK-3 receptor antagonist demonstrated by antagonizing neurokinin B on the NK-3 receptor in the rat portal vein. Synonyms: R486; L-α-Aspartyl-L-seryl-L-phenylalanyl-L-tryptophyl-β-alanyl-L-leucyl-L-methioninamide; L-Methioninamide, L-α-aspartyl-L-seryl-L-phenylalanyl-L-tryptophyl-β-alanyl-L-leucyl-; H-Asp-Ser-Phe-Trp-β-Ala-Leu-Met-NH2. Grades: ≥95%. CAS No. 132041-95-3. Molecular formula: C41H57N9O10S. Mole weight: 868.01. | |
| 1- (3, 5-Bis (trifluoromethyl) phenyl) ethoxy) -3- (p-tolyl) morpholino) methyl) -5-oxo-4, 5-dihydro-1H-1, 2, 4-triazol-1-yl) phosphonic Acid | 1- (3, 5-Bis (trifluoromethyl) phenyl) ethoxy) -3- (p-tolyl) morpholino) methyl) -5-oxo-4, 5-dihydro-1H-1, 2, 4-triazol-1-yl) phosphonic Acid is an impurity of Fosaprepitant (F727300), which a selective neurokinin-1 (NK-1) receptor antagonist, an antiemetic drug, and a Aprepitant (A729800) prodrug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C31H31F6N4O6P, Molecular Weight: 700.57. US Biological Life Sciences. | Worldwide |
| 1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid | 1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: Fosaprepitant Impurity F; (4-Benzyl-3-{[(2S,3R)-2-{(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-methylphenyl)-4-morpholinyl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid; Phosphonic acid, [3-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-methylphenyl)-4-morpholinyl]methyl]-4,5-dihydro-5-oxo-4-(phenylmethyl)-1H-1,2,4-triazol-1-yl]-. Molecular formula: C31H31F6N4O6P. Mole weight: 700.56. | |
| (1'R,2R,3R)-Defluoro Fosaprepitant Dimeglumine | (1'R,2R,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'R,2R,3R)-Fosaprepitant Dimeglumine | (1'R,2R,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'R,2R,3S)-Defluoro Fosaprepitant Dimeglumine | (1'R,2R,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'R,2S,3R)-Defluoro Fosaprepitant Dimeglumine | (1'R,2S,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'R,2S,3R)-Fosaprepitant Dimeglumine | (1'R,2S,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Uses: Antiemetics. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'R,2S,3S)-Defluoro Fosaprepitant Dimeglumine | (1'R,2S,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'R,2S,3S)-Fosaprepitant Dimeglumine | (1'R,2S,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'S,2R,3R)-Defluoro Fosaprepitant Dimeglumine | (1'S,2R,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'S,2R,3R)-Fosaprepitant Dimeglumine | (1'S,2R,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'S,2R,3S)-Defluoro Fosaprepitant Dimeglumine | (1'S,2R,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'S,2R,3S)-Fosaprepitant Dimeglumine | (1'S,2R,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1S,2S,3R)-Aprepitant | (1S,2S,3R)-Aprepitant is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C23H21F7N4O3. Mole weight: 516.44. | |
| (1'S,2S,3R)-Defluoro Fosaprepitant Dimeglumine | (1'S,2S,3R)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'S,2S,3R)-Fosaprepitant Dimeglumine | (1'S,2S,3R)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| (1'S,2S,3S)-Defluoro Fosaprepitant Dimeglumine | (1'S,2S,3S)-Defluoro Fosaprepitant Dimeglumine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1). Molecular formula: C37H57F6N6O16P. Mole weight: 986.84. | |
| (1'S,2S,3S)-Fosaprepitant Dimeglumine | (1'S,2S,3S)-Fosaprepitant Dimeglumine is an isomer of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid (2:1); [3-[[(2S,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol (1:2). Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. | |
| [1(S)-Phenylethoxy]-Aprepitant | [1(S)-Phenylethoxy]-Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Group: Biochemicals. Grades: Highly Purified. CAS No. 170902-81-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| 2-[(1S)-1-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)-2-oxoethoxy]acetic Acid Methyl Ester | 2-[(1S)-1-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)-2-oxoethoxy]acetic Acid Methyl Ester is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Intermediate in the preparation of aprepitant metabolites. Synonyms: Methyl [(1S)-1-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-2-(4-fluorophenyl)-2-oxoethoxy]acetate; [(1S)-1-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)-2-oxoethoxy]acetic Acid Methyl Ester; Acetic acid, 2-[(1S)-1-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)-2-oxoethoxy]-, methyl ester. Grades: ≥95%. CAS No. 419574-29-1. Molecular formula: C21H17F7O5. Mole weight: 482.34. | |
| 2,2-Bis[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)ethanone | 2,2-Bis[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)ethanone is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Intermediate in the preparation of aprepitant metabolites. Synonyms: Ethanone, 2,2-bis[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-; 2,2-Bis{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-1-(4-fluorophenyl)ethan-1-one. Grades: ≥95%. CAS No. 419574-40-6. Molecular formula: C28H19F13O3. Mole weight: 650.43. | |
| 2-Hydroxy-4-(phenylmethyl)-3-morpholinone | 2-Hydroxy-4-(phenylmethyl)-3-morpholinone is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Morpholinone, 2-hydroxy-4-(phenylmethyl)-; Fosaprepitant Impurity 23; 4-Benzyl-2-hydroxy-3-morpholinone; 2-Hydroxy-4-benzylmorpholin-3-one. Grades: 95%. CAS No. 287930-73-8. Molecular formula: C11H13NO3. Mole weight: 207.23. | |
| 2- (R)-[1- (R)- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy]-3- (S)-fluorophenylmorpholine | 2- (R) -[1- (R) - (3, 5-Bis (trifluoromethyl) phenyl) ethoxy]-3- (S) -fluorophenylmorpholine[Aprepitant-M2] is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A metabolite of aprepitant. Synonyms: Aprepitant-M2; (2R, 3S)-2- ( (R)-1- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy)-3- (4-fluorophenyl)morpholine; Morpholine, 2-[ (1R)-1-[3, 5-bis (trifluoromethyl)phenyl]ethoxy]-3- (4-fluorophenyl)-, (2R,3S)-; (2R- (2aR*), 3a)-2- (1- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy)-3- (4-fluorophenyl)morpholine. Grades: 96%. CAS No. 171338-27-5. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
| 2- (R)-[1- (S)- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy]-3- (S)-fluorophenylmorpholine | 2- (R)-[1- (S)- (3, 5-Bis (trifluoromethyl)phenyl)ethoxy]-3- (S)-fluorophenylmorpholine is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A metabolite of aprepitant. Synonyms: Fosaprepitant Impurity 32; Morpholine, 2-[ (1S)-1-[3, 5-bis (trifluoromethyl)phenyl]ethoxy]-3- (4-fluorophenyl)-, (2R,3S)-; [2R-[2aR*), 3a]-2-[1-[3, 5-Bis (trifluoromethyl)phenyl]ethoxy]-3- (4-fluorophenyl)morpholine. Grades: 95%. CAS No. 170729-79-0. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
| (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine | (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Intermediate in the preparation of enantiomerically pure aprepitant diastereomers and derivatives. Synonyms: Aprepitant dehydro dealkyl; Desfluro Aprepitant; 2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-; (R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine; 2alpha-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine; Aprepitant Impurity 6. Grades: ≥95%. CAS No. 380499-07-0. Molecular formula: C20H16F7NO2. Mole weight: 435.33. | |
| (2R,3R,1S)-Aprepitant | (2R,3R,1S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1242175-34-3. Pack Sizes: 1mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| (2R,3R)-2-benzhydryl-N-benzylquinuclidin-3-amine-(D)-10-camphorsulfonate | (2R,3R)-2-benzhydryl-N-benzylquinuclidin-3-amine-(D)-10-camphorsulfonate is an impurity of Maropitant. Maropitant is a neurokinin (NK1) receptor antagonist. Synonyms: Maropitant Impurity 1. Grades: 99% by HPLC. CAS No. 2243127-08-2. Molecular formula: C37H46N2O4S. Mole weight: 614.85. | |
| (2S,3R,1R)-Aprepitant | (2S,3R,1R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1185502-97-9. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| (2S,3S,1R)-Aprepitant | (2S,3S,1R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. (2S,3S,1R)-Aprepitant is also a useful synthetic intermediate in the synthesis of morpholine tachykinin receptor antagonist prodrugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 172822-28-5. Pack Sizes: 1mg. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.429999999999. US Biological Life Sciences. | Worldwide |
| (2S,3S)-2-benzhydryl-N-benzylquinuclidin-3-amine-(1R)-10-camphorsulfonate | (2S,3S)-2-benzhydryl-N-benzylquinuclidin-3-amine-(1R)-10-camphorsulfonate is an impurity of Maropitant. Maropitant is a neurokinin (NK1) receptor antagonist. Synonyms: Maropitant Impurity A; Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1R,4S)-, compd. with (2S,3S)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine (1:1). Grades: 99% by HPLC. CAS No. 862543-55-3. Molecular formula: C37H46N2O4S. Mole weight: 614.85. | |
| 3-Des-(4-fluorophenyl) 3-(4-Fluorobiphen-3-yl) Aprepitant | 3-Des-(4-fluorophenyl) 3-(4-Fluorobiphen-3-yl) is a derivative of Aprepitant, which is a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 5-{[(2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-(3-fluoro-4-biphenylyl)-4-morpholinyl]methyl}-2,4-dihydro-3H-1,2,4-triazol-3-one; 3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(3-fluoro[1,1'-biphenyl]-4-yl)-4-morpholinyl]methyl]-2,4-dihydro-. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| 4-Benzyl-2,3-morpholinedione | 4-Benzyl-2,3-morpholinedione is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 4-(Phenylmethyl)-2,3-morpholinedione; 2,3-Morpholinedione, 4-(phenylmethyl)-. Grades: ≥95%. CAS No. 110843-90-8. Molecular formula: C11H11NO3. Mole weight: 205.21. | |
| 5-Chloromethyl-2H-1,2,4-triazolin-3-one | 5-Chloromethyl-2H-1,2,4-triazolin-3-one is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 5-(Chloromethyl)-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-(Chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 5-Chloromethyl-2,3-dihydro-4H-1,2,4-triazol-3-one; 3-Chloromethyl-1,2,4-triazolin-5-one. Grades: ≥95%. CAS No. 252742-72-6. Molecular formula: C3H4ClN3O. Mole weight: 133.54. | |
| (5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone | (5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is a diastereomeric byproduct in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A diastereomeric byproduct formed during the synthesis of aprepitant metabolites. Synonyms: 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6R)-; Aprepitant M2 Metabolite 5-Epimer. Grades: ≥95%. CAS No. 419574-33-7. Molecular formula: C20H16F7NO3. Mole weight: 451.33. | |
| (5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone | (5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is an active metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Morpholinone, 6-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6S)-; ent-Aprepitant-M3; Aprepitant M3 Metabolite (1S,5R,6S)-Isomer. Molecular formula: C20H16F7NO3. Mole weight: 451.33. | |
| Acetylaszonalenin | Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes. It acts as an antagonist of neurokinin-1 (NK1) receptor. Synonyms: 2-acetoxy-n,n,n-trimethylethanaminium iodide; (+)-Acetylaszonalenin; (5aS,13aR,14aS)-5-acetyl-14a-(1,1-dimethyl-2-propen-1-yl)-5a,13a,14,14a-tetrahydro-indolo[3',2':4,5]pyrrolo[2,1-c][1,4]benzodiazepine-7,13(5H,12H)-dione; LL-S490β; Antibiotic LL-S490&beta. Grades: ≥95%. CAS No. 42230-55-7. Molecular formula: C25H25N3O3. Mole weight: 415.48. | |
| Ac-leu-asp-gln-trp-phe-gly-nh2 | Heterocyclic Organic Compound. Alternative Names: AC-LEU-ASP-GLN-TRP-PHE-GLY-NH2;R396;NEUROKININ NK-2 RECEPTOR ANTAGONIST;Ac-L-Leu-L-Asp-L-Gln-L-Trp-L-Phe-Gly-NH2. CAS No. 129809-09-2. Molecular formula: C39H51N9O10. Mole weight: 805.8765. Purity: 0.96. IUPACName: (3S)-3-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-4-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-oxobutanoic acid. Density: 1.322g/cm³. Catalog: ACM129809092. | |
| Aprepitant | Aprepitant an antiemetic and antagonist of the neurokinin-1 (NK1) receptor (Ki = 3nM; IC50 = 0.09nM for the human receptor).It is selective for NK1 over NK3 receptors (Ki = 454.1nM for human NK3). In vivo, aprepitant (1mg/Kg) prevents plasma extravasation into the esophagus of guinea pigs induced by substance P. It also reduces NK1-agonist-induced foot tapping in gerbils. Formulations containing aprepitant have been used to prevent chemotherapy-induced nausea and vomiting. Group: Biochemicals. Alternative Names: 5-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-1, 2-dihydro-3H-1, 2, 4-triazol-3-one; Emend; L 754030; MK-869; ONO-7436. Grades: Highly Purified. CAS No. 170729-80-3. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C23H21F7N4O3, Molecular Weight: 534.43. US Biological Life Sciences. | Worldwide |
| Aprepitant | Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a K d of 86 pM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0869; MK-869; L-754030. CAS No. 170729-80-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10052. | |
| Aprepitant EP Impurity B | Aprepitant EP Impurity B is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-3-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one. CAS No. 2348441-62-1. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant EP Impurity C | Aprepitant EP Impurity C is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-4-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one; 4-Defluoro-4-(p-fluorophenyl)aprepitant. CAS No. 2348441-63-2. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant glucuronide | Aprepitant glucuronide is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C29H29F7N4O9. Mole weight: 710.55. | |
| Aprepitant Impurity 10 HCl | Aprepitant Impurity 10 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: (2R,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride; 1447693-83-5. CAS No. 1447693-83-5. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 11 HCl | Aprepitant Impurity 11 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 12 HCl | Aprepitant Impurity 12 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
| Aprepitant Impurity 13 | Aprepitant Impurity 13 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant Impurity 14 | Aprepitant Impurity 14 is a derivative of Aprepitant, which is a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Des-(4-fluorophenyl) 3-(R)-(4'-Fluorobiphen-4-yl) Aprepitant. Molecular formula: C29H25F7N4O3. Mole weight: 610.52. | |
| Aprepitant Impurity 15 | Aprepitant Impurity 15 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C23H22F6N4O4. Mole weight: 532.43. | |
| Aprepitant Impurity 16 | Aprepitant Impurity 16 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. CAS No. 638990-20-2. Molecular formula: C22H24N2O5. Mole weight: 396.44. | |
| Aprepitant Impurity 17 | Aprepitant Impurity 17 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C21H19F6NO3. Mole weight: 447.37. | |
| Aprepitant Impurity 18 | Aprepitant Impurity 18 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C12H7F9O2. Mole weight: 354.17. | |
| Aprepitant Impurity 19 | Aprepitant Impurity 19 is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3,7-Dimethyl-3-octanol. CAS No. 78-69-3. Molecular formula: C10H22O. Mole weight: 158.28. | |
| Aprepitant Impurity 1 HCl | Aprepitant Impurity 1 HCl is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Molecular formula: C20H18F7NO2.HCl. Mole weight: 473.81. | |
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