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| Product | Description | |
|---|---|---|
| Nintedanib | Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3 , FGFR1/2/3 and PDGFRα/β with IC 50 s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBF 1120. CAS No. 656247-17-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50904. |  |
| Nintedanib-[13C,d3] | Nintedanib-[13C,d3] is the labelled analogue of Nintedanib. Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). Synonyms: Nintedanib 13CD3; [13C,2H3]-BIBF 1120; [13C,2H3]-Intedanib; [13C,2H3]-Vargatef; methyl (Z)-3-(((4-(N-methyl-2-(4-(methyl-13C-d3)piperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate; Ofev-13C,d3. Grade: ≥95%. Molecular formula: C30[13C]H30D3N5O4. Mole weight: 543.65. |  |
| Nintedanib esylate | Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3 , FGFR1/2/3 and PDGFRα/β with IC 50 s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBF 1120 esylate. CAS No. 656247-18-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-11106. | |
| Nintedanib Impurity 12 | Nintedanib Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1139458-48-2. Molecular formula: C26H23N3O4. Mole weight: 441.49. Catalog: APB1139458482. |  |
| Nintedanib Impurity 6 | Nintedanib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038972-16-5. Molecular formula: C13H18N4O3. Mole weight: 278.31. Catalog: APB1038972165. | |
| Nintedanib Impurity 9 | Nintedanib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1860012-61-8. Molecular formula: C9H10N2O4. Mole weight: 210.19. Catalog: APB1860012618. | |
| Desmethyl Nintedanib | An impurity of Nintedanib, which is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/73 nM. Synonyms: Nintedanib Impurity G; 2,3-Dihydro-3-[[[4-[[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-methyl Ester-1H-indole-6-carboxylic Acid; (Z)-Methyl 3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate. CAS No. 894783-61-0. Molecular formula: C30H31N5O4. Mole weight: 525.60. | |
| 1,2-bis(4-methylpiperazin-1-yl)ethanone | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-(5CI); Nintedanib Impurity E. Grade: ≥95%. CAS No. 856843-88-4. Molecular formula: C12H24N4O. Mole weight: 240.35. | |
| 2,2'-(piperazine-1,4-diyl)bis(N-methyl-N-(4-nitrophenyl)acetamide) | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Nintedanib Impurity G. Grade: ≥95%. CAS No. 2410649-54-4. Molecular formula: C22H26N6O6. Mole weight: 470.48. | |
| 2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: 4-Methyl-N-(4-nitrophenyl)-1-piperazineacetamide; Nintedanib Impurity F. Grade: ≥95%. CAS No. 708279-23-6. Molecular formula: C13H18N4O3. Mole weight: 278.31. | |
| 2-chloro-N-methyl-N-(4-nitrophenyl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Acetamide, 2-chloro-N-methyl-N-(4-nitrophenyl)-; α-Chloro-N-methyl-p-nitroacetanilide; Nintedanib Impurity B. Grade: ≥95%. CAS No. 2653-16-9. Molecular formula: C9H9ClN2O3. Mole weight: 228.63. | |
| (3Z)-2,3-Dihydro-2-oxo-3-(phenyl-1-piperidinylmethylene)-1H-indole-6-carboxylic acid methyl ester | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Nintedanib Impurity U. Grade: ≥95%. CAS No. 2102162-79-6. Molecular formula: C22H22N2O3. Mole weight: 362.42. | |
| Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))(3Z,3'E)-bis(2-oxoindoline-6-carboxylate) | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Nintedanib Impurity 50. Grade: ≥95%. CAS No. 2410284-90-9. Molecular formula: C56H52N8O8. Mole weight: 965.08. | |
| Methyl (3Z) -3-{[ (4-{methyl[ (4-methylpiperazin-1-yl) acetyl]amino}phenyl) amino] (phenyl) methylidene}-2-oxo-2, 3-dihydro-1H-indole-6-carboxylate | Methyl (3Z) -3-{[ (4-{methyl[ (4-methylpiperazin-1-yl) acetyl]amino}phenyl) amino] (phenyl) methylidene}-2-oxo-2, 3-dihydro-1H-indole-6-carboxylate. Group: Biochemicals. Alternative Names: Nintedanib; Ofev; BIBF 1120; Vargatef. Grades: Highly Purified. CAS No. 928326-83-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C31H33O4N5. US Biological Life Sciences. |  Worldwide |
| (Z)-Methyl 3-(((4-(N-methyl-2-(piperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Synonyms: Nintedanib metabolite M3; Nintedanib impurity I; 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-. Grade: ≥95%. CAS No. 334951-61-0. Molecular formula: C30H31N5O4. Mole weight: 525.60. | |
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