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10,10'-Oxybis(5-methyl-10,11-dihydro-5H-dibenzo[b,f]azepine) is an impurity in the synthesis of Metapramine (M225830), a norepinephrine reuptake inhibitor without affecting the reuptake of serotonin or dopamine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C30H28N2O. US Biological Life Sciences.
1-(4-(4-Hydroxyphenyl)butan-2-yl)-1H-indole-5,6-diol can be obtained from DL-Norepinephrine Hydrochloride (N674500) which is Antagonist of dibutyryl cyclic-AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release. Analytical Standard, Impurity of Drug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C18H19NO3, Molecular Weight: 297.35. US Biological Life Sciences.
1-(4-(4-Hydroxyphenyl)butan-2-yl)-1H-indole-5,6-diol is an impurity of Norepinephrine, which is widely used as an injectable drug for the treatment of critically low blood pressure. Synonyms: Dobutamine Aminochrome Impurity; 1-[4-(4-Hydroxyphenyl)-2-butanyl]-1H-indole-5,6-diol; 1H-Indole-5,6-diol, 1-[3-(4-hydroxyphenyl)-1-methylpropyl]-; Aminochrome Impurity 1. Grade: ≥95%. CAS No. 2514709-72-7. Molecular formula: C18H19NO3. Mole weight: 297.35.
1-phenyl-3-azabicyclo[3.1.0]hexan-2-one
1-phenyl-3-azabicyclo[3.1.0]hexan-2-one is an milnacipran impurity. Milnacipran is an antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. Group: Biochemicals. Grades: Highly Purified. CAS No. 153275-06-0. Pack Sizes: 100mg, 1g. Molecular Formula: C11H11NO, Molecular Weight: 173.21. US Biological Life Sciences.
Worldwide
1-Phenyl-3-azabicyclo[3.1.0]hexan-2-one
1-Phenyl-3-azabicyclo[3.1.0]hexan-2-one is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: 1-Phenyl-3-aza-bicyclo[3.1.0]hexan-2-one; Milnacipran Impurity 12; 3-Azabicyclo[3.1.0]hexan-2-one, 1-phenyl-. Grade: ≥95%. CAS No. 153275-06-0. Molecular formula: C11H11NO. Mole weight: 173.21.
1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one
1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one is an intermediate in the synthesis of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: 1-Phenyl-2-oxo-3-oxabicyclo[3.1.0]hexane; Milnacipran Impurity 31. Grade: ≥95%. CAS No. 63106-93-4. Molecular formula: C11H10O2. Mole weight: 174.20.
(1R, 1'R, 2S, 2'S) -2, 2'- ( ( (2-Aminopropane -1, 3-diyl) bis (oxy) ) bis ( methyl ene ) ) bis (phenylcyclopropane carboxamide)
(1R, 1'R, 2S, 2'S) -2, 2'- ( ( (2-Aminopropane -1, 3-diyl) bis (oxy) ) bis ( methyl ene ) ) bis (phenylcyclopropane carboxamide) is an impurity of the drug Milnacipria (M344600), which is an antidepressnant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C25H31N3O4, Molecular Weight: 437.53. US Biological Life Sciences.
(1R,1'R,2S,2'S)-2,2'-(((2-Aminopropane-1,3-diyl)bis(oxy))bis(methylene))bis(phenylcyclopropanecarboxamide) is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: Milnacipran Dimer Impurity A. Grade: 95%. Molecular formula: C25H31N3O4. Mole weight: 437.53.
(1R, 2R) -2- (Hydroxy methyl ) -1-phenylcyclopropane carboxylic Acid is an impurity in the synthesis of Milnacipran (M344600). Milnacipran is an antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C11H12O3, Molecular Weight: 192.21. US Biological Life Sciences.
(1R,2R)-2-(Hydroxymethyl)-1-phenylcyclopropanecarboxylic Acid is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: trans-2-(Hydroxymethyl)-1-phenylcyclopropanecarboxylic acid; Milnacipran EP Impurity C; Milnacipran Impurity 9; Cyclopropanecarboxylic acid, 2-(hydroxymethyl)-1-phenyl-, (1R,2R)-. Grade: 95%. CAS No. 22613-99-6. Molecular formula: C11H12O3. Mole weight: 192.21.
(1R, 2R) -rel-2- [ (1, 3-Dihydro-1, 3-dioxo-2H-isoindol-2-yl) methyl ] -N, N-diethyl-1-phenyl-cyclopropane carboxamide is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 907205-34-9. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C22H22N2O3. US Biological Life Sciences.
(1R, 2R) -rel-N, N-Diethyl-2- (hydroxy methyl ) -1-phenyl-cyclopropane carboxamide is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1797131-72-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C15H21NO2. US Biological Life Sciences.
(1R, 2S) -rel-N, N-Diethyl-2- [ [ [ (4- methyl phenyl) sulfonyl] oxy] methyl ] -1-phenyl-cyclopropane carboxamide is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 923037-67-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C22H27NO4S. US Biological Life Sciences.
(1S, 2S) -2- (Acetoxy methyl ) -1-phenylcyclopropane carboxylic Acid is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C13H14O4. US Biological Life Sciences.
( (1S, 2S) -2- (Diethylcarbamoyl) -2-phenylcyclopropyl) methyl Acetate is an intermediate in synthesizing rac,trans-Milnacipran Hydrochloride (M344625), which is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C17H23NO3. US Biological Life Sciences.
((1S,2S)-2-(Diethylcarbamoyl)-2-phenylcyclopropyl)methyl Acetate is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Molecular formula: C17H23NO3. Mole weight: 289.37.
(1S, 2S) -2- (Hydroxy methyl ) -1-phenylcyclopropane carboxylic Acid is an impurity in the synthesis of Milnacipran (M344600). Milnacipran is an antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C11H12O3, Molecular Weight: 192.21. US Biological Life Sciences.
(1S,2S)-2-(Hydroxymethyl)-1-phenylcyclopropanecarboxylic Acid is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: Cyclopropanecarboxylic acid, 2-(hydroxymethyl)-1-phenyl-, (1S,2S)-. Molecular formula: C11H12O3. Mole weight: 192.21.
2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: Duloxetine EP Impurity E; 2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthol hydrochloride (1:1); 1-Naphthalenol, 2-[3-(methylamino)-1-(2-thienyl)propyl]-, hydrochloride (1:1). Grade: ≥95%. CAS No. 1033719-36-6. Molecular formula: C18H20ClNOS. Mole weight: 333.87.
2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol is an impurity of Duloxetine (D721000), a dual serotonin and norepinephrine reuptake inhibitor (SNRI) used in treatment of stress urinary incontinence. Group: Biochemicals. Grades: Highly Purified. CAS No. 1033719-36-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
2-Desamino 2-Chloro Norepinephrine
2-Desamino 2-Chloro Norepinephrine is an impurity of Noradrenaline, which is widely used as an injectable drug for the treatment of critically low blood pressure. Synonyms: 4-(2-Chloro-1-hydroxyethyl)-1,2-benzenediol; α-(Chloromethyl)-3,4-dihydroxy-benzyl alcohol; 1-(3,4-Dihydroxyphenyl)-2-chloroethanol; 1,2-Benzenediol, 4-(2-chloro-1-hydroxyethyl)-; Norepinephrine Impurity 35; Noradrenaline (Norepinephrine) Impurity 13. Grade: ≥95%. CAS No. 5530-29-0. Molecular formula: C8H9ClO3. Mole weight: 188.61.
2-(Hydroxymethyl)-1-phenylcyclopropanecarbonitrile is an impurity of Milnacipran, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Synonyms: Milnacipran EP Impurity D; Cyclopropanecarbonitrile, 2-(hydroxymethyl)-1-phenyl-. CAS No. 60788-55-8. Molecular formula: C11H11NO. Mole weight: 173.21.
An impurity of Norepinephrine. Norepinephrine, also known as noradrenaline, is a marker for catecholamine-secreting tumors such as pheochromocytoma, paraganglioma, and neuroblastoma. Synonyms: 1,2,3,4-Tetrahydro-2-(1-methylethyl)-4,6,7-isoquinolinetriol; N-Isopropyl-1,2,3,4-tetrahydro-4,6,7-isoquinolinetriol. CAS No. 2771193-17-8. Molecular formula: C12H17NO3. Mole weight: 223.27.
(2S,3R)-2-Amino-3-(3-(benzoyloxy)-4-hydroxyphenyl)-3-hydroxypropanoic Acid is an impurity of Droxidopa, which is a synthetic amino acid precursor used as a prodrug to the neurotransmitter norepinephrine (noradrenaline). Molecular formula: C16H15NO6. Mole weight: 317.29.
3-(1,3-Benzodioxol-5-yl)serine
An impurity of Droxidopa. Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). It is capable of crossing the protective blood-brain barrier. Synonyms: 3,4-methylenedioxyphenylserine; alpha-Amino-beta-hydroxy-1,3-benzodioxole-5-propanoic acid; Droxidopa Impurity 22; N-Benzyloxycarbonyl DL-threo-βα-Amino-β-hydroxy-1,3-benzodioxole-5-propanoic acid. CAS No. 56672-56-1. Molecular formula: C10H11NO5. Mole weight: 225.20.
3,3'-(Methylimino)bis[1-(2-thienyl)-1-propanone Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: 3,3''-(Methylazanediyl)bis(1-(thiophen-2-yl)propan-1-one) Hydrochloride; 1-Propanone, 3,3'-(methylimino)bis[1-(2-thienyl)-, hydrochloride (1:1); Duloxetine Impurity 7. Grade: ≥95%. CAS No. 494221-37-3. Molecular formula: C15H18ClNO2S2. Mole weight: 343.89.
3,3'-(Naphthalene-1,3-diyl)bis(N-methyl-3-(thiophen-2-yl)propan-1-amine) Dihydrochloride is an impurity of Duloxetine (D721000), a dual serotonin and norepinephrine reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
3,3'-(Naphthalene-1,3-diyl)bis(N-methyl-3-(thiophen-2-yl)propan-1-amine) Dihydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: 3,3'-(1,3-Naphthalenediyl)bis[N-methyl-3-(2-thienyl)-1-propanamine] dihydrochloride; 1,3-Naphthalenedipropanamine, N1,N3-dimethyl-γ,γ'-di-2-thienyl-, hydrochloride (1:2). Molecular formula: C26H32Cl2N2S2. Mole weight: 507.58.
3,4-Di-O-benzyl DL-erythro-Droxidopa Hydrochloride is a prominent pharmaceutical compound, serving as a robust prodrug effectively transformed into norepinephrine. Primarily designed to study manifestations linked to Parkinson's disease, orthostatic hypotension and neurogenic orthostatic hypotension. This compound showcases an augmented level of stability and bioavailability owing to its hydrochloride formulation. Uses: Protected dl-erythro-droxidopa. Synonyms: DL-erythro-3-[3,4-Bis(benzyloxy)phenyl]serine Hydrochloride; β-Hydroxy-3-(phenylmethoxy)-O-(phenylmethyl)-erythro-L-tyrosine Hydrochloride; (βS)-O-Benzyl-3-(benzyloxy)-β-hydroxy-L-tyrosine hydrochloride (1:1); L-Tyrosine, β-hydroxy-3-(phenylmethoxy)-O-(phenylmethyl)-, (βS)-, hydrochloride (1:1); Droxidopa Impurity 28. Grade: ≥95%. CAS No. 73594-44-2. Molecular formula: C23H24ClNO5. Mole weight: 429.89.
3-(Methylamino)-1-(thiophen-3-yl)propane-1-ol
3-(Methylamino)-1-(thiophen-3-yl)propane-1-ol, is an impurity of Duloxetine (D721000), that acts as an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI) (1,2). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate (3). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C8H13NOS, Molecular Weight: 171.26. US Biological Life Sciences.
Worldwide
3-(Methylamino)-1-(thiophen-3-yl)propane-1-ol
3-(Methylamino)-1-(thiophen-3-yl)propane-1-ol is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: 3-(Methylamino)-1-(3-thienyl)-1-propanol; 3-Thiophenemethanol, α-[2-(methylamino)ethyl]-; Duloxetine Impurity A. Molecular formula: C8H13NOS. Mole weight: 171.26.
(3R)-N-Methyl-3-(3-methylphenoxy)-3-phenylpropan-1-amine Hydrochloride is an impurity of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: (R)-N-methyl-3-phenyl-3-(m-tolyloxy)propan-1-amine hydrochloride; (3R)-N-Methyl-3-(3-methylphenoxy)-3-phenyl-1-propanamine hydrochloride (1:1); Benzenepropanamine, N-methyl-γ-(3-methylphenoxy)-, (γR)-, hydrochloride (1:1); Atomoxetine EP Impurity D HCl (Atomoxetine USP Related Compound B (R-Isomer)). CAS No. 1643684-05-2. Molecular formula: C17H22ClNO. Mole weight: 291.81.
(3R)-N-Methyl-3-(4-methylphenoxy)-3-phenylpropan-1-amine Hydrochloride is an impurity of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: (R)-N-methyl-3-phenyl-3-(p-tolyloxy)propan-1-amine hydrochloride; (3R)-N-Methyl-3-(4-methylphenoxy)-3-phenyl-1-propanamine hydrochloride (1:1); Benzenepropanamine, N-methyl-γ-(4-methylphenoxy)-, (γR)-, hydrochloride (1:1); Atomoxetine EP Impurity C HCl. Grade: ≥95%. CAS No. 1643684-06-3. Molecular formula: C17H22ClNO. Mole weight: 291.81.
(3S)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: DLX-ISO 3; Duloxetine EP Impurity F; (γS)-N-Methyl-γ-(1-naphthalenyloxy)-3-thiophenepropanamine; (3S)-N-Methyl-3-(1-naphthyloxy)-3-(3-thienyl)-1-propanamine; 3-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)-; (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine. Grade: ≥95%. CAS No. 959392-22-4. Molecular formula: C18H19NOS. Mole weight: 297.41.
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: rac Dehydro-O-desmethyl Venlafaxine; 1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine. CAS No. 1346600-38-1. Molecular formula: C16H23NO. Mole weight: 245.37.
4-(1-Cyclohexyl-2-(dimethylamino)ethyl)phenol
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: rac Deoxy-O-desmethyl Venlafaxine; Cyclohexyl-4-hydroxy-N,N-dimethylbenzeneethanamine. CAS No. 1346605-18-2. Molecular formula: C16H25NO. Mole weight: 247.38.
[4-Hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienylmethanone Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: Methanone, [4-hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienyl-, monohydrochloride; Methanone, [4-hydroxy-1-methyl-4-(2-thienyl)-3-piperidinyl]-2-thienyl-, hydrochloride (1:1). CAS No. 494221-40-8. Molecular formula: C15H18ClNO2S2. Mole weight: 343.89.
4'-Hydroxy Atomoxetine
4'-Hydroxyatomoxetine is an impurity of Atomoxetine, a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Uses: A metabolite of atomoxetine, a norepinephrine uptake blocker. Synonyms: Atomoxetine 4-Hydroxy Impurity; 4-Hydroxyatomoxetine; p-Hydroxy Atomoxetine; Phenol, 3-methyl-4-[(1R)-3-(methylamino)-1-phenylpropoxy]-; 3-Methyl-4-((R)-3-methylamino-1-phenyl-propoxy)-phenol. Grade: ≥90%. CAS No. 435293-66-6. Molecular formula: C17H21NO2. Mole weight: 271.35.
5-(4-methoxyphenyl)-1-oxa-3-azaspiro[5.5]undecane
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: Venlafaxine Impurity 13. CAS No. 727728-51-0. Molecular formula: C16H23NO2. Mole weight: 261.36.
Atomoxetine EP Impurity A HCl
Atomoxetine EP Impurity A HCl is a hydrochloride circuit impurity of Atomoxetine manifesting as a selective norepinephrine reuptake inhibitor (NRI) prescribed predominantly for ADHD, albeit sporadically utilized for major depressive disorder. Synonyms: N-methyl-3-phenoxy-3-phenyl-propylamine hydrochloride. Grade: > 95%. CAS No. 873310-33-9. Molecular formula: C16H20NOCl. Mole weight: 277.79.
Atomoxetine EP Impurity F
Atomoxetine EP Impurity F is a derivative of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: 3-Fluoro (S)-Atomoxetine; (3S)-3-(3-Fluoro-2-methylphenoxy)-N-methyl-3-phenylpropan-1-amine; (3S)-N-Methyl-3-(3-fluoro-2-methylphenoxy)-3-phenylpropan-1-amine. Molecular formula: C17H20FNO. Mole weight: 273.34.
Atomoxetine-N-amide
Atomoxetine-N-amide is a derivative of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: Atomoxetine-N-Amide Impurity; (R)-1-Methyl-1-(3-phenyl-3-(o-tolyloxy)propyl)urea; Atomoxetine Impurity 2. Molecular formula: C18H22N2O2. Mole weight: 298.38.
Centanafadine Lactam
Centanafadine Lactam is an impurity or metabolite of Centanafadine, which is a dual norepinephrine-dopamine transporter inhibitor used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Synonyms: (1S,5R)-5-(2-Naphthyl)-3-azabicyclo[3.1.0]hexan-2-one; 3-Azabicyclo[3.1.0]hexan-2-one, 5-(2-naphthalenyl)-, (1S,5R)-. Molecular formula: C15H13NO. Mole weight: 223.27.
Desmethoxy Venlafaxine Hydrochloride
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Molecular formula: C16H25NO. HCl. Mole weight: 283.84.
Desvenlafaxine benzoate
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: Phenol, 4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)-, benzoate (1:1). CAS No. 1147940-37-1. Molecular formula: C23H31NO4. Mole weight: 385.5.
Desvenlafaxine fumarate
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: O-Desmethylvenlafaxine fumarate; 4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol fumarate. Grade: 95%. CAS No. 93414-04-1. Molecular formula: C20H29NO6. Mole weight: 379.45.
(±)-Duloxetine
(±)-Duloxetine is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-; N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine; N-Methyl-3-(1-naphthoxy)-3-(2-thienyl)propylamine; (+/-)-Duloxetine. Grade: 95%. CAS No. 116817-13-1. Molecular formula: C18H19NOS. Mole weight: 297.41.
Duloxetine EP Impurity F Hydrochloride
Duloxetine EP Impurity F Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride; Duloxetine Related Compound F. Grade: 98%. CAS No. 2748376-86-3. Molecular formula: C18H20ClNOS. Mole weight: 333.88.
Duloxetine Related Compound H
Duloxetine Related Compound H is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (S)-Duloxetine Succinamide; 4-[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]-4-oxobutanoic Acid. Grade: 98%. CAS No. 199191-66-7. Molecular formula: C22H23NO4S. Mole weight: 397.49.
Erythro-β,3-dihydroxy-DL-tyrosine
Erythro-β,3-dihydroxy-DL-tyrosine is an impurity of Droxidopa, which is a synthetic amino acid precursor used as a prodrug to the neurotransmitter norepinephrine (noradrenaline). Synonyms: Droxidopa Impurity 11 (DL-erythro-Droxidopa); DL-erythro-3,4-Dihydroxyphenylserine; Erythro-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic Acid; Erythro-3-(3,4-Dihydroxyphenyl)serine; rel-(βR)-β,3-Dihydroxy-D-tyrosine; DL-Tyrosine, β,3-dihydroxy-, erythro-; Serine, 3-(3,4-dihydroxyphenyl)-, DL-erythro-; D-Tyrosine, β,3-dihydroxy-, (βR)-rel-. CAS No. 16322-99-9. Molecular formula: C9H11NO5. Mole weight: 213.19.
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: Decyclohexanol-ethoxycarbonyl-O-desmethyl Venlafaxine; α-[(Dimethylamino)methyl]-4-hydroxybenzeneacteic Acid Ethyl Ester. CAS No. 1346600-77-8. Molecular formula: C13H19NO3. Mole weight: 237.3.
Fluoronaphthalene
An impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used for major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. Synonyms: Naphthalene, 1-fluoro-; 1-Fluoronaphthalene; NSC 4690; α-Fluoronaphthalene; Duloxetine USP Impurity G; Duloxetine EP Impurity G. Grade: ≥95%. CAS No. 321-38-0. Molecular formula: C10H7F. Mole weight: 146.16.
Milnacipran-[d5] hydrochloride
Milnacipran-[d5] hydrochloride is a labelled impurity of Milnacipran. Milnaciprana is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat fibromyalgia. Synonyms: Milnacipran-d5 hydrochloride; Milnacipran-d5 HCl. Grade: > 95%. Molecular formula: C15H18ClN2OD5. Mole weight: 287.85.
(±)-N-Methylduloxetine
(±)-N-Methylduloxetine is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: 2-Thiophenepropanamine, N,N-dimethyl-γ-(1-naphthalenyloxy)-; N,N-Dimethyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine; N,N-Dimethyl-3-((1-naphthalenyl)oxy)-3-(2-thienyl)propanamine; N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine. Grade: 95%. CAS No. 116817-11-9. Molecular formula: C19H21NOS. Mole weight: 311.44.
Norepinephrine-[d6] Hydrochloride
Norepinephrine-[d6] Hydrochloride is a labelled analog of Norepinephrine, which is an impurity of Epinephrine. Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors. Synonyms: noradrenaline. Grade: 95% by CP; 98% atom D. CAS No. 1219803-04-9. Molecular formula: C8H6D6ClNO3. Mole weight: 211.68.
Norepinephrine-D6 Hydrochloride
Norepinephrine-D6 Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1219803-04-9. Molecular formula: C8H6D6ClNO3. Mole weight: 211.68. Catalog: APB1219803049.
(R)-Desmethyl Atomoxetine Hydrochloride
(R)-Desmethyl Atomoxetine Hydrochloride is a metabolite of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Synonyms: (R)-γ-(2-Methylphenoxy)benzenepropanamine Hydrochloride; Atomoxetine N-Desmethyl Impurity; (R)-3-(2-Methylphenoxy)-3-phenyl-1-propanamine hydrochloride (1:1); Benzenepropanamine, γ-(2-methylphenoxy)-, (3R)-, hydrochloride (1:1). Molecular formula: C16H20ClNO. Mole weight: 277.79.
(R)-Duloxetine
(R)-Duloxetine is the R-configuration of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (γR)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine; (R)-N-Methyl-3-(1-naphthoxy)-3-(2-thienyl)propylamine; (3R)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine; 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γR)-; Duloxetine EP Impurity A; Duloxetine USP Related Compound A. Grade: 95%. CAS No. 116539-60-7. Molecular formula: C18H19NOS. Mole weight: 297.41.
(S)-N-Desmethyl Duloxetine Hydrochloride
(S)-N-Desmethyl Duloxetine Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (γS)-γ-(1-Naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (S)-γ-(1-Naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (3S)-3-(1-Naphthyloxy)-3-(2-thienyl)-1-propanamine hydrochloride (1:1); 2-Thiophenepropanamine, γ-(1-naphthalenyloxy)-, (γS)-, hydrochloride (1:1). CAS No. 1798887-69-0. Molecular formula: C17H18ClNOS. Mole weight: 319.85.
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