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5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C18H20FN3O4. CAS No. 82419-36-1. Prepack ID 11654280-5g. Molecular Weight 361.37. See USA prepack pricing.
Ofloxacin
Ofloxacin. Group: Biochemicals. Alternative Names: 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; Ofloxacine; DL-8280. Grades: Highly Purified. CAS No. 82419-36-1. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C18H20FN3O4. US Biological Life Sciences.
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Ofloxacin
Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase. Ofloxacin shows inhibitory activity against vaccinia virus (VV). Uses: Scientific research. Group: Natural products. Alternative Names: Hoe-280. CAS No. 82419-36-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0125.
Ofloxacin
Ofloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic. It has antimicrobial activity. It can inhibit DNA gyrase, Topo II (topoisomerase II) and Topo IV (Topo II α). Uses: Anti-bacterial agents; anti-infective agents, urinary; nucleic acid synthesis inhibitors. Synonyms: RS-10085; RS 10085; RS10085; DL-8280; DR-3355; ORF-28489; Ru-43280; 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; Ofloxacine; HOE-280; Exocin; Flobacin; Floxil; Floxin; Monoflocet; Ocuflox. Grades: >98%. CAS No. 82419-36-1. Molecular formula: C18H20FN3O4. Mole weight: 361.37.
Labeled fluorinated quinolone antibacterial. Group: Biochemicals. Alternative Names: 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl-d8)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; Ofloxacine-d8; DL-8280-d8; HOE-280-d8; Exocin-d8; Flobacin-d8; Floxil-d8; Floxin-d8; Monoflocet-d8; Ocuflox-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Ofloxacin EP Impurity A
Ofloxacin EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 82419-35-0. Molecular Formula: C13H9F2NO4. Mole Weight: 281.22. Catalog: APB82419350.
Ofloxacin EP Impurity B
Ofloxacin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123155-82-8. Molecular Formula: C17H20FN3O2. Mole Weight: 317.36. Catalog: APB123155828.
Ofloxacin EP Impurity C
An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: 2,3-Dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid. Grades: > 95%. Molecular formula: C18H21N3O4. Mole weight: 343.39.
Ofloxacin EP Impurity C
Ofloxacin EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 95848-94-5. Molecular Formula: C18H21N3O4. Mole Weight: 343.38. Catalog: APB95848945.
Ofloxacin EP Impurity D
An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: 9-Piperazino Ofloxacin; 10-Fluoro-2,3-dihydro-3-methyl-9-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; Ofloxacin EP Impurity D. Grades: > 95%. CAS No. 197291-75-1. Molecular formula: C18H20FN3O4. Mole weight: 361.38.
Ofloxacin EP Impurity D
Ofloxacin EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 197291-75-1. Molecular Formula: C18H20FN3O4. Mole Weight: 361.37. Catalog: APB197291751.
Ofloxacin EP Impurity E
Ofloxacin EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 82419-52-1. Molecular Formula: C17H18FN3O4. Mole Weight: 347.35. Catalog: APB82419521.
Ofloxacin EP Impurity F
Ofloxacin EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104721-52-0. Molecular Formula: C18H20FN3O5. Mole Weight: 377.37. Catalog: APB104721520.
An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: Decarboxyl Ofloxacin; 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one; (±)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one. Grades: > 95%. CAS No. 123155-82-8. Molecular formula: C17H20FN3O2. Mole weight: 317.37.
Ofloxacin Impurity E
An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: Desmethyl Ofloxacin; 9-Fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; Ofloxacin EP Impurity E. Grades: > 95%. CAS No. 82419-52-1. Molecular formula: C17H18FN3O4. Mole weight: 347.346.
Ofloxacin N-Oxide Acetic Acid Salt (Impurity F)
An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: Ofloxacin N-Oxide Acetic Acid Salt;9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Acetic Acid Salt. Grades: > 95%. CAS No. 104721-52-0. Molecular formula: C18H20FN3O5. C2H4O2. Mole weight: 377.38 60.05.
2,3-Dehydro ofloxacin
2,3-Dehydro ofloxacin. Group: Biochemicals. Alternative Names: 9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid. Grades: Highly Purified. CAS No. 115841-55-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H18FN3O4. US Biological Life Sciences.
Ofloxacin intermediate. Group: Biochemicals. Alternative Names: 9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid. Grades: Highly Purified. CAS No. 82419-35-0. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Decarboxyl ofloxacin
Decarboxyl ofloxacin. Group: Biochemicals. Alternative Names: 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one; (±)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one. Grades: Highly Purified. CAS No. 123155-82-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H20FN3O2. US Biological Life Sciences.
Worldwide
Decarboxyl ofloxacin
Heterocyclic Organic Compound. Alternative Names: 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one; (±)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one. CAS No. 123155-82-8. Molecular formula: C17H20FN3O2. Mole weight: 317.36. Catalog: ACM123155828.
Desmethyl Ofloxacin
Desmethyl Ofloxacin. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ofloxacin USP RC A,Ofloxacin Imp. E (EP), (RS)-9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid, Ofloxacin USP Related Compound A. CAS No. 82419-52-1. IUPAC Name: (RS)-9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid. Molecular Formula: C17H18FN3O4. Mole Weight: 347.34. Catalog: APS82419521. SMILES: CC1COc2c (N3CCNCC3)c (F)cc4C (=O)C (=CN1c24)C (=O)O. Format: Neat.
Desmethyl Ofloxacin-d8 Hydrochloride
A labeled metabolite of Ofloxacin. Group: Biochemicals. Alternative Names: 9-Fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl-d8)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Levofloxacin
Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Ofloxacin. CAS No. 100986-85-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 5 g. Product ID: HY-B0330.
Levofloxacin-13C,d3
Levofloxacin-13C,d3 is 13C and deuterium labeled levofloxacin. Levofloxacin, C18H20FN3O4, is a type of quinolone drug with broad-spectrum antibacterial effects. Group: Isotope-labeled synthetic intermediates. Alternative Names: (-)-Ofloxacin-13C,d3. CAS No. 1261398-33-7. Molecular formula: C1713CH17D3FN3O4. Mole weight: 365.38. Appearance: Solid. Purity: ≥98.0%. Canonical SMILES: O=C1C2=CC (F)=C (N3CCN (CC3)[13C] ([2H]) ([2H])[2H])C4=C2N (C=C1C (O)=O)[C@@H] (C)CO4. Catalog: ACM1261398337.
Levofloxacin-d8
Heterocyclic Organic Compound. Alternative Names: (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl-d8)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Hemihydrate;Levofloxacin-d8;Levofloxacin-D8/ Ofloxacin-D8;Levooxacin-d8. CAS No. 1217716-71-6. Molecular formula: C18H12D8FN3O4. Mole weight: 369.416797424. Catalog: ACM1217716716.
Levofloxacin-d8
Labeled S-(-)-Form of Ofloxacin. An antibiotic used against gram-negative organisms. Group: Biochemicals. Alternative Names: (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl-d8)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Hemihydrate. Grades: Highly Purified. CAS No. 1217716-71-6,unlabeled: 100986-85-4. Pack Sizes: 1mg. Molecular Formula: C??H??D?FN?O?, Molecular Weight: 369.42. US Biological Life Sciences.
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Levofloxacin-d8
Levofloxacin-d 8 is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (-)-Ofloxacin-d8. CAS No. 1217716-71-6. Pack Sizes: 1 mg. Product ID: HY-B0330S.
Levofloxacin Hemihydrate
The hydrate form of Levofloxacin, an Ofloxacin derivative, could be commonly used as an antibacterial agent through influencing DNA replication. It is an antibiotic with activity against gram-negative bacteria. Uses: Anti-bacterial agents. Synonyms: RWJ 25213; RWJ-25213; RWJ25213; (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Hemihydrate; Dynaquin; Levofloxacin Hydrate. Grades: 98%. CAS No. 138199-71-0. Molecular formula: C18H20FN3O4.1/2H2O. Mole weight: 370.38.
Levofloxacin hydrochloride
Levofloxacin (Levofloxacin) is a levofloxacin isomer, water solubility is 8 times of ofloxacin, belongs to the third generation of quinolone antibacterial drugs. Synonyms: (s)-ofloxacin; 7H-Pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylicacid, 9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (S)-; Cravit; HR355; LeChemicalbookvaquin; RWJ25213-097; Tavanic; (-)-(S)-9-Fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7H-pyrido(1, 2, 3-de)-1, 4-benzoxazine-6-carboxylicacid. CAS No. 100986-85-4. Product ID: PAP-0061. Molecular formula: C18H20FN3O4. Category: Anti-Infectives. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; Levofloxacin hydrochloride; PAP-0061; Anti-Infectives; C18H20FN3O4; 100986-85-4. Appearance: White to faint yellow. Standard: Chp/USP/EP. Chemical Name: (s)-ofloxacin. Grade: Pharmaceutical Grade. Solubility: chloroform: soluble10mg/mL. Storage: Keep in dark place,Sealed in dry,2-8°C. Applications: Oral levofloxacin is mainly used for mild and moderate infections caused by sensitive bacteria, and the dosage is 250mg to 500mg each time, once a day. The corresponding indications are extremely broad - including but not limited to: community-acquired pneumonia, bacterial sinusitis, acute bronchitis, complex and uncomplex skin tissue or skin structural infections, chronic bacterial prostatitis, complex urinary tract infections. Product Description: Levoflo
Levofloxacin hydrochloride
Levofloxacin ((-)-Ofloxacin) hydrochloride is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrochloride can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrochloride shows anti-orthopoxvirus activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Ofloxacin hydrochloride. CAS No. 177325-13-2. Pack Sizes: 1 g. Product ID: HY-B0330B.
Levofloxacin Impurity 8
An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (R)-Ofloxacin Carboxylic Acid (Dextrofloxacin Difluoro Impurity); (3R)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid. Grades: > 95%. CAS No. 110548-07-7. Molecular formula: C13H9F2NO4. Mole weight: 281.22.
Levofloxacin Lactate Liposome
Levofloxacin lactate is the levorotatory form of ofloxacin, which has about twice the antibacterial activity of ofloxacin. This product is a pre-formulated liposome with levofloxacin lactate. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Levofloxacin (Standard)
Levofloxacin (Standard) is the analytical standard of Levofloxacin. This product is intended for research and analytical applications. Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Ofloxacin (Standard). CAS No. 100986-85-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0330R.
N,N-Desethylene Ofloxacin Hydrochloride
N,N-Desethylene Ofloxacin Hydrochloride is an Ofloxacin (O245750) derivative. Group: Biochemicals. Alternative Names: 9-Fluoro-2, 3-dihydro-3-methyl-10-[[2- (methylamino) ethyl]amino]-7-oxo-7H-pyrido[1, 2, 3-de]-1, 4-benzoxazine-6-carboxylic Acid Hydrochloride. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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(R)-Ofloxacin
An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; (+)-Ofloxacin. Grades: > 95%. CAS No. 100986-86-5. Molecular formula: C18H20FN3O4. Mole weight: 361.38.
(R)-Ofloxacin
Heterocyclic Organic Compound. Alternative Names: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; (+)-Ofloxacin; (R)-(+)-Ofloxacin; D-Ofloxacin; DR 3354; d-Levofloxacin. CAS No. 100986-86-5. Molecular formula: C18H20FN3O4. Mole weight: 361.37. Catalog: ACM100986865.
(R)-Ofloxacin
(R)-Ofloxacin. Group: Biochemicals. Alternative Names: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; (+)-Ofloxacin; (R)-(+)-Ofloxacin. Grades: Highly Purified. CAS No. 100986-86-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C18H20FN3O4. US Biological Life Sciences.
2, 3, 4, 5-Tetrafluoro-α - [ [ [ (1S) -2-hydroxy-1-methylethyl] amino] methylene] - β-oxo-benzenepropanoic Acid Ethyl Ester is used in the synthesis of the drug Levofloxacin (L360000), which is a S-(-) form of Ofloxacin (O245750), an antibiotic used against gram-negative organisms. Group: Biochemicals. Grades: Highly Purified. CAS No. 110548-02-2. Pack Sizes: 100mg, 500mg. Molecular Formula: C15H15F4NO4, Molecular Weight: 349.28. US Biological Life Sciences.
2, 3, 4, 5-Tetrafluoro-α - [ [ [ (1S) -2-hydroxy-1-methylethyl] amino] methylene] - β-oxo-benzenepropanoic Acid Methyl Ester is used in the synthesis of the drug Levofloxacin (L360000), which is a S-(-) form of Ofloxacin (O245750), an antibiotic used against gram-negative organisms. Group: Biochemicals. Grades: Highly Purified. CAS No. 1213269-48-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C14H13F4NO4, Molecular Weight: 335.25. US Biological Life Sciences.
Worldwide
2,3,4-Trichloronitrobenzene
2,3,4-Trichloronitrobenzene is a useful synthetic intermediate that is mainly used as the starting material in the synthesis of third generation quinolone antibacterial drugs, such as Lomefloxacin (L469415, HCl) and Ofloxacin (O245750). 2,3,4-Trichloronitrobenzene is also used as the starting material in the synthesis of Aclonifen (A190200); a compound used as a pesticide and herbicide. Group: Biochemicals. Grades: Highly Purified. CAS No. 17700-09-3. Pack Sizes: 5g, 10g. Molecular Formula: C6H2Cl3NO2, Molecular Weight: 226.44. US Biological Life Sciences.
Worldwide
Irloxacin
Irloxacin is a new quinolone derivative, and shows greater activity with an acid pH. It has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. In vitro activity of irloxacin against mycobacteria (20 M. tuberculosis, 17 M. avium, 5 Mycobacterium bovis, 5 Mycobacterium chelonae, 5 Mycobacterium fortuitum and 1 Mycobacterium gadium) using the Bactec at pH 6.8 and 5.0, with other quinolones (ofloxacin, ciprofloxacin, pefloxacin and 27753 RP) were compared. All quinolones tested showed good activity against mycobacteria at pH 6.8 and 5.0. Irloxacin at pH 5.0 had a greater activity against M. avium. Group: Others. Alternative Names: E 3432; E3432; E-3432; Irloxacin; Pirfloxacin. CAS No. 91524-15-1. Molecular formula: C16H13FN2O3. Mole weight: 300.29. Appearance: Solid powder. Purity: >98%. IUPACName: 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-. Canonical SMILES: O=C (C1=CN (CC)C2=C (C=C (F)C (N3C=CC=C3)=C2)C1=O)O. Catalog: ACM91524151.
Norfloxacin
Norfloxacin and ofloxacin, levofloxacin, ciprofloxacin belong to the third generation fluoroquinolone antibacterial drugs, with a broad spectrum of antibacterial action, especially against aerobic gram-negative bacteria with high antibacterial activity, against the following bacteria in vitro has a good antibacterial effect: Most of the bacteria in the Enterobacteriaceae family, including E. coli, Enterobacter cloacae, Enterobacter aerogenes, E. coli, Klebsiella, Chemicalbook Proteus, Salmonella, Shigella, Vibrio, Yersinia, etc. Norfloxacin also has antibacterial activity against multi-drug resistant bacteria in vitro. The penicillin-resistant Neisseria gonorrhoeae, Haemophilus influenzae and Moraxella catarrh also have good antibacterial effects. Norfloxacin is A bactericide that causes bacterial death by inhibiting DNA synthesis and replication by acting on the A subunit of bacterial DNA helicase. CAS No. 70458-96-7. Product ID: PAP-0063. Molecular formula: C16H18FN3O3. Category: Antibiotic. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; Norfloxacin; PAP-0063; Antibiotic; C16H18FN3O3; 70458-96-7. Appearance: Crystalline Powder. Standard: USP. Grade: CEP/ISO. Color: White to yellow. Physical State: Crystalline Powder. Solubility: Very slightly soluble in water, slightly soluble in acetone and in ethanol (96 per cent). Storage: Keep in dark place,Sealed in dry,Room Temperature. Applications: C
Pazufloxacin
Pazufloxacin (T-3761), a new quinolone derivative, showed broad and potent antibacterial activity. T-3761 showed good efficacy in mice against systemic, pulmonary, and urinary tract infections with gram-positive and gram-negative bacteria, including quinolone-resistant Serratia marcescens and Pseudomonas aeruginosa. The in vivo activity of T-3761 was comparable to or greater than those of ofloxacin, ciprofloxacin, norfloxacin, and tosufloxacin against most infection models in mice. The activities of T-3761 were lower than those of tosufloxacin against gram-positive bacterial systemic and pulmonary infections in mice but not against infections with methicillin-resistant Staphylococcus aureus. T-3761 had a broad spectrum of activity and had potent activity against gram-positive and -negative bacteria. The MICs of T-3761 against 90% of the methicillin-susceptible Staphylococcus aureus, methicillin-susceptible and -resistant Staphylococcus epidermidis, and Clostridium spp. tested were 0.39 to 6.25 micrograms/ml. The MBCs of T-3761 were either equal to or twofold greater than the MICs. The 50% inhibitory concentrations of T-3761 for DNA gyrases isolated from E. coli and P. aeruginosa were 0.88 and 1.9 micrograms/ml, respectively. Synonyms: T-3761; T3761; T 3761. Grades: >98%. CAS No. 127045-41-4. Molecular formula: C16H15FN2O4. Mole weight: 318.3.
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