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Canagliflozin Ring Opening Impurity is an impurity of Canagliflozin, which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor used in the treatment of type 2 diabetes and obesity. Synonyms: (2S,3R,4R,5R)-1-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)hexane-1,2,3,4,5,6-hexaol; D-Glucitol, 1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-; 1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol. Molecular formula: C24H27FO6S. Mole weight: 462.53.
Everolimus Ring-Opening Impurity
An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Retroaldol Degradation Product. Grades: > 95%. CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.25.
Ezetimibe ring-opening dehydrate impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L31) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (αR,βS)-β-[(4-Fluorophenyl)amino]-α-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanoic Acid. Grades: > 95%. CAS No. 1292292-63-7. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
Loxoprofen Ring-opening Impurity
Loxoprofen Ring-opening Impurity is a degradation product of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: 4-(1-Carboxyethyl)-δ-oxo-benzenehexanoic Acid; 2-[4-(2-Oxo-6-carboxy-pentyl)phenyl-propanoic Acid. Grades: > 95%. CAS No. 1091621-61-2. Molecular formula: C15H18O5. Mole weight: 278.3.
Tacrolimus Ring-opening Impurity
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacrolimus Ring-opening Impurity. Grades: > 95%. Molecular formula: C44H69NO12. Mole weight: 804.04.
Benzyl Penicilloic Acid HCl (Mixture of Diastereomers)
An impurity of Penicilloic Acid which is a thiazolidinedicarboxylic acid obtained from the penicillins by the hydrolytic opening of the lactam ring. Grades: > 95%. Molecular formula: C16H20N2O5S.HCl. Mole weight: 388.87.
Benzyl Penicilloic Acid Mono-Sodium Salt (Mixture of Diastereomers)
An impurity of Penicilloic Acid which is a thiazolidinedicarboxylic acid obtained from the penicillins by the hydrolytic opening of the lactam ring. Grades: > 95%. Molecular formula: C16H19N2O5S.Na. Mole weight: 374.39.
Dapagliflozin Open Sugar Impurity
Dapagliflozin Open Sugar Impurity is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin open sugar impurity; 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; (2S,3R,4R,5R)-1-(4-Chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol; Dapagliflozin ring opening impurity; (1R,2S,3R,4R)-1-(4-Chloro-3-(4-ethoxybenzyl)phenyl)hexane-1,2,3,4,5,6-hexaol. Molecular formula: C21H27ClO7. Mole weight: 426.89.
2-? [ [ (1R, ?2R) ?-?2-? [ [4-? (1, ?2-?Benzisothiazol-?3-?yl) ?-?1-?piperazinyl] ?methyl] ?cyclohexyl] ?methyl] ?-1H-?isoindole-?1, ?3 (2H) ?-?dione is an intermediate in synthesizing Lurasidone Opened Imide (L474935), an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1260025-92-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C27H30N4O2S. US Biological Life Sciences.
An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: 2-(3-METHOXYPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; 2-(3-methoxypropyl)-1,1-dioxothieno[3,2-e]thiazine-6-sulfonamide; B0464-284943; 2-(3-METHOXYPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 171273-35-1. Molecular formula: C10H14N2O5S3. Mole weight: 338.42.
(2R,4S)-2-[(2S,5S)-5-(4-Hydroxyphenyl)-3,6-dioxo-2-piperazinyl]-5,5-dimethyl-4-thiazolidinecarboxylic Acid is an impurity in the synthesis of N-(Penicillan-6-yl) Open Ring Amoxicillinamide Disodium Salt , whch is an impurity of Amoxicillin (A634235); a semi-synthetic antibiotic related to Penicillin (P233500). Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H19N3O5S. US Biological Life Sciences.
[2S-[2α,5α,6 β (S*) ] ] -6- [ [ (4-Hydroxyphenyl) [ [ [ (4-nitrophenyl) methoxy] carbonyl] amino] acetyl] amino] -3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo [3. 2. 0] heptane-2-carboxylic Acid is an impurity in the synthesis of N-(Penicillan-6-yl) Open Ring Amoxicillinamide Disodium Salt, which is an impurity of Amoxicillin (A634235); a semi-synthetic antibiotic related to Penicillin (P233500). Antibacterial. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H23N4NaO9S. US Biological Life Sciences.
4-Oxo Diazepam Open Ring Impurity is one of Diazepam impurities. Diazepam is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: Diazepam Impurity 5; 2-(N-acethyl-N-methylamino)-5-chlorobenzophenone. CAS No. 36271-03-1. Molecular formula: C16H14ClNO2. Mole weight: 287.74.
5-Beta-Hydroxy-Drospirenone-17-Propanol
5-Hydroxy Drospirenone Ring-opened Alcohol Impurity is an impurity of Drospirenone. Synonyms: (5R, 6R, 7R, 8R, 9S, 10R, 13S, 14S, 15S, 16S, 17S)-Octadecahydro-5, 17-dihydroxy-17-(3-hydroxypropyl)-10, 13-dimethyl-3H-dicyclopropa[6, 7:15, 16]cyclopenta[a]phenanthren-3-one; 17α-[3-Hydroxypropyl]-6β,7β:15β,16β-dimethylen-5β-androstan-5,17β-ol-3-one. Grades: > 95%. CAS No. 1357252-81-3. Molecular formula: C24H36O4. Mole weight: 388.54.
Ampicillin open ring dimer
An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: (4S)-2-{1-[(R)-2-amino-2-phenylacetamido]-2-[(1R)-2-{[(4S)-4-carboxy-5,5-dimethylthiazolidin-2-yl]methylamino}-2-oxo-1-phenylethylamino]-2-oxoethyl}-5,5-dimethylthiazolidine-4-carboxylic acid. Molecular formula: C31H40N6O7S2. Mole weight: 672.82.
Anidulafungin Impurity A
Anidulafungin Impurity A is a degradation impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Synonyms: Anidulafungin Open-chain Degradant. Molecular formula: C58H73N7O17. Mole weight: 1140.25.
Arginine Ring-opened Aztreonam
Arginine Ring-opened Aztreonam is an Aztreonam (A965200) Impurity I. Aztreonam is the first totally synthetic monocyclic β-lactam antibiotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C19H31N9O10S2, Molecular Weight: 609.63. US Biological Life Sciences.
Worldwide
Aztreonam Impurity A
Aztreonam Impurity A is an metabolite of Aztreonam, a synthetic monocyclic β-lactam antibiotic. Synonyms: SQ 26992; Open Ring Aztreonam; [S-[R*,R*-(Z)]]-2-[[(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-3-(sulfoamino)-butanoic acid. Grades: > 95%. CAS No. 87500-74-1. Molecular formula: C13H19N5O9S2. Mole weight: 453.45.
Cefdinir Impurity 4
Cefdinir impurity formed by hydrolytic degradation pathway β-lactam ring opened lactones. Synonyms: [2RS-[2α [RS* (Z)], 5β ]]-α -[[ (2-Amino-4-thiazolyl) (hydroxyimino)acetyl]amino]-1, 2, 5, 7-tetrahydro-5-methyl-7-oxo-4H-furo[3, 4-d][1, 3]thiazine-2-acetic Acid. Grades: > 95%. CAS No. 178422-45-2. Molecular formula: C14H15N5O6S2. Mole weight: 413.43.
Cefdinir Impurity H
Cefdinir Impurity H is one of Cefdinir impurities. Cefdinir is a semi-synthetic, broad-spectrum antibiotic, used for soft tissue infections and respiratory tract infections. Synonyms: Cefdinir impurity H; 178949-04-7; Cefdinir decarboxy open ring lactone; 2O1193FN39; (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-hydroxyimino-N-[(5-methyl-7-oxo-1,2,4,5-tetrahydrofuro[3,4-d][1,3]thiazin-2-yl)methyl]acetamide; (Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N -(((2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H -furo(3,4-d)(1,3)thiazin-2-yl)methyl(acetamide; 2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N -(((2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H -furo(3,4-d)(1,3)thiazin-2-yl)methyl(acetamide, (Z)-; UNII-2O1193FN39; SCHEMBL23871786; (Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-{[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl}acetamide; 4-Thiazoleacetamide, 2-amino-alpha-(hydroxyimino)-N-((1,2,5,7-tetrahydro-5-methyl-7-oxo-4H-furo(3,4-d)(1,3)thiazin-2-yl)methyl)-; 4-THIAZOLEACETAMIDE, 2-AMINO-.ALPHA.-(HYDROXYIMINO)-N-((1,2,5,7-TETRAHYDRO-5-METHYL-7-OXO-4H-FURO(3,4-D)(1,3)THIAZIN-2-YL)METHYL)-. Molecular formula: C14H15N5O6S2. Mole weight: 413.43.
Cyclosporin A-Derivative 1 Free base
Cyclosporin A-Derivative 1 Free base is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A open ring; N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester; Cyclosporin A-Derivative 1 (Free base); Cyclosporin A seco(MeGly-MeLeu) Methyl Ester; Leu-Val-Leu-Ala-{d-Ala}-Leu-Leu-Val-{Aaa}-{Abu}-{Sar}; LVLA-{d-Ala}-LLV-{Aaa}-{Abu}-{Sar}. Grades: ≥95%. CAS No. 286852-20-8. Molecular formula: C65H117N11O14. Mole weight: 1276.69.
Dapagliflozin Impurity 5
Dapagliflozin Impurity 5 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; Dapagliflozin Open Ring Impurity. Grades: >90%. CAS No. 2100872-88-4. Molecular formula: C21H27ClO7. Mole weight: 426.89.
Donepezil Open-Ring Keto Acid
Donepezil Open-Ring Keto Acid is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: 2-[3-(1-Benzylpiperidin-4-yl)-2-oxopropyl]-4,5-dimethoxybenzoic acid. CAS No. 197010-25-6. Molecular formula: C24H29NO5. Mole weight: 411.498.
Dorzolamide Impurity A
Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Uses: Carbonic anhydrase inhibitors. Synonyms: L671152; MK507; L 671152; MK 507; L-671152; MK-507; Trusopt. Grades: >98%. CAS No. 120279-96-1. Molecular formula: C10H16N2O4S3. Mole weight: 324.44.
Ertapenem Ring Open Impurity
An impurity of Ertapenem. Ertapenem is a carbapenem antibiotic. Synonyms: 1H-Pyrrole-2-acetic acid, 5-carboxy-4-[[(3S,?5S)?-5-[[(3-carboxyphenyl)?amino]?carbonyl]?-3-pyrrolidinyl]?thio]?-2,?3-dihydro-α-[(1R)?-1-hydroxyethyl]?-3-methyl-, (αS,?2S,?3R)?-. Grades: > 95%. CAS No. 357154-27-9. Molecular formula: C22H27N3O8S. Mole weight: 493.54.
Ezetimibe Azetidinone (Ring-opened Impurity)
A degradation product of the antihyperlipoproteinem ic Ezetimibe. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ezetimibe Azetidinone Ring-opened Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L8) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Azetidinone Ring-opened Sodium Salt Impurity (Technical Grade, >75%). Grades: > 95%. CAS No. 1391053-63-6. Molecular formula: C24H23F2NO4. Mole weight: 427.45.
Ezetimibe (Diacid Impurity)
An open-ringed diacid impurity of Ezetimibe. Group: Biochemicals. Alternative Names: (2R) -2- [ (S) - [ (4-Fluorophenyl) amino] [4- (phenylmethoxy) phenyl] methyl] pentanedioic Acid. Grades: Highly Purified. CAS No. 1013025-04-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ezetimibe Ring-Open Impurity
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L15) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide. Grades: > 95%. CAS No. 1197811-72-5. Molecular formula: C24H23FNO3. Mole weight: 411.45.
Fenoterol Degradation Impurity A
An impurity of Fenoterol. Fenoterol is a β2 adrenoreceptor agonist designed to open up the airways to the lungs. It is classed as sympathomimetic β2 agonist and asthma medication. Synonyms: ,?2,?3,?4-tetrahydro-2-[2-(4-hydroxyphenyl)?-1-methylethyl]?-4,?6,?8-Isoquinolinetriol. Grades: > 95%. CAS No. 161040-25-1. Molecular formula: C18H21NO4. Mole weight: 315.37 80.91.
Flupirtine Dimer
Flupirtine Dimer is an impurity of Flupirtine. Flupirtine is a selective neuronal potassium channel opener that acts as an Analgesic, having substituted pyridine with central analgesic properties. Synonyms: diethyl (6,6'-diamino-2,2'-bis((4-fluorobenzyl)amino)-[3,3'-bipyridine]-5,5'-diyl)dicarbamate. Grades: 98%. CAS No. 1417916-52-9. Molecular formula: C30H32F2N8O4. Mole weight: 606.62.
Gabapentin Related Compound A
Gabapentin Lactam (Gabapentin EP Impurity A; Gabapentin USP Related Compound A) reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntingtons disease. It opens mitochondrial ATP-dependent potassium channels. Group: Biochemicals. Alternative Names: 3-Azaspiro-[4,5]decan-3-one; Gabapentin lactam; USP Gabapentin Related Compound A; Gabapentin EP Impurity A; Gabapentin USP Related Compound A. Grades: Highly Purified. CAS No. 64744-50-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C?H??NO, Molecular Weight: 153.22. US Biological Life Sciences.
It is an impurity of Flupirtine. Flupirtine is a selective neuronal potassium channel opener that acts as an Analgesic, having substituted pyridine with central analgesic properties. Synonyms: Acetamide, N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-; Flupirtine Impurity 04. Grades: 99% by HPLC. CAS No. 91941-04-7. Molecular formula: C14H15FN4O. Mole weight: 274.29.
N-(Penicillan-6-yl) Open Ring Amoxicillinamide Disodium Salt
N-(Penicillan-6-yl) Open Ring Amoxicillinamide Disodium Salt is an impurity of Amoxicillin, which is an antibiotic used to treat a number of bacterial infections including middle ear infections, strep throat, pneumonia, skin infections, and urinary tract infections. Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[2-amino-2-(4-hydroxyphenyl)acetyl]amino]-2-[(2R,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, (2S,5R,6R)- (1:2); (2S,5R,6R)-6-((2R)-2-(2-Amino-2-(4-hydroxyphenyl)acetamido)-2-((2R,4S)-4-carboxy-5,5-dimethylthiazolidin-2-yl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Disodium Salt; Disodium (2S,5R,6R)-6-({(2R)-2-{[amino(4-hydroxyphenyl)acetyl]amino}-2-[(2R,4S)-4-carboxylato-5,5-dimethyl-1,3-thiazolidin-2-yl]acetyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate. Grades: 90%. Molecular formula: C24H29N5Na2O8S2. Mole weight: 625.62.
Paclitaxel Oxetane Ring-Opened 3-Acetyl 4-Benzoyl Impurity is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-bis(acetyloxy)-4-[(benzoyloxy)methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetramethyl-12-oxo-6,10-methanobenzocyclodecen-8-yl ester, (αR,βS)-; (1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-Bis(acetyloxy)-4-[(benzoyloxy)methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetramethyl-12-oxo-6,10-methanobenzocyclodecen-8-yl (αR,βS)-β-(benzoylamino)-α-hydroxybenzenepropanoate; β-(Benzoylamino)-α-hydroxybenzenepropanoic acid (αR,βS)-(1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-bis(acetyloxy)-4-[(benzoyloxy)methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetramethyl-12-oxo-6,10-methanobenzocyclodecen-8-yl ester; Paclitaxel EP Impurity M (5S-isomer); Paclitaxel Oxetane ring opened, acetyl and benzoyl migrated; (1S, 2S, 3R, 4S, 5S, 7S, 8S, 10R, 13S)-5, 10-diacetyloxy-1, 2, 4, 7-tetrahydroxy-8, 12, 15, 15-tetramethyl-9-oxo-4-(phenylcarbonyloxymethyl)tricyclo[9. 3. 1. 03, 8]pentadec-11-en-13-yl (2R,3S)-2-hydroxy-3-phenyl-3-(phenylcarbonylamino)propanoate. Grades: ≥95%. CAS No. 932042-85-8. Molecular formula: C47H53NO15. Mole weight: 871.94.
Piperacillinylamplicillin (Open Ring) Disodium Salt
Piperacillinylamplicillin (Open Ring) Disodium Salt is an impurity of Piperacillin, which is a broad-spectrum semi-synthetic antibiotic related to Penicillin. Synonyms: (2S,5R,6R)-6-((2R)-2-(2-((4S)-4-Carboxy-5,5-dimethylthiazolidin-2-yl)-2-((R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido)acetamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Disodium Salt. Molecular formula: C39H44N8Na2O11S2. Mole weight: 910.92.
Piperacillinylamplicillin (Open Ring) Triethylamine Salt
Piperacillinylamplicillin (Open Ring) Triethylamine Salt is an impurity of Piperacillin, which is a broad-spectrum semi-synthetic antibiotic related to Penicillin. Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[2-[(4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]-2-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]acetyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, compd. with N,N-diethylethanamine (1:1); (2S,5R,6R)-6-({(2R)-2-[([(4S)-4-Carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl]{[(2R)-2-{[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino}-2-phenylacetyl]amino}acetyl)amino]-2-phenylacetyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid N,N-diethylethanamine (1:1). Molecular formula: C39H46N8O11S2.C6H15N. Mole weight: 968.15.
Prasugrel open cycle
An impurity of Prasugrel.Prasugrel is a platelet inhibitor. It can be used to prevent formation of blood clots. Synonyms: 2-Pentanone, 1-[2-(acetyloxy)?-6,?7-dihydrothieno[3,?2-c]?pyridin-5(4H)?-yl]?-5-chloro-1-(2-fluorophenyl)?-. Grades: > 95%. Molecular formula: C20 H21 Cl F N O3 S. Mole weight: 409.91.
An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; (4R)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide; SCHEMBL3576264; (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 165117-54-4. Molecular formula: C10H16N2O6S3. Mole weight: 356.44.
Rivaroxaban Open-Ring N-Methyl Impurity
An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: 4'-Desmorpholino 4'-[N-(5-chloro-2-carboxy-thienyl)N-(5-Carboxy-3-oxa-pentyl)]amino Rivaroxaban; (S)-5-chloro-N-(4-(5-((5-chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)-N-(2-(2-(methylamino)-2-oxoethoxy)ethyl)thiophene-2-carboxamide. CAS No. 1807455-76-0. Molecular formula: C25H24Cl2N4O6S2. Mole weight: 611.52.
An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. CAS No. 2183841-60-1. Molecular formula: C10H17N3O5S3. Mole weight: 355.45.
S-Clopidogrel N-Methyl Impurity
S-Clopidogrel N-Methyl Impurity is an open ring impurity of Clopidogrel. Synonyms: Methyl (2S)-(2-Chlorophenyl)-2-[N-methyl-N-(2-thiophen-2-ylethyl)amino]acetate; Methyl (2S)-(2-Chlorophenyl)-2-[methyl(2-thiophen-2-ylethyl)amino]ethanoate; Clopidogrel Impurity I. Grades: > 95%. CAS No. 1346605-15-9. Molecular formula: C16H18ClNO2S. Mole weight: 323.84.
Tigecycline impurity (ring-open)
Tigecycline (open C-ring D-ring) Quinone Trifluoroacetic Acid Salt
Tigecycline (open C-ring D-ring) quinone Trifluoroacetic Acid Salt is a salt of Tigecycline (open C-ring D-ring) quinone, an impurity of Tigecycline (T440015). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C26H32N4O8 · x(C2HF3O2). US Biological Life Sciences.
Worldwide
Valdecoxib impurity (Ring-open N-OH)
An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Deoxybenzoin Oxime; (1E)-1,2-Diphenylethanone Oxime; (E)-2-Phenylacetophenone Oxime. CAS No. 26306-06-9. Molecular formula: C14H13NO. Mole weight: 211.27.
(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-{[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl}acetamide is one of Cefdinir impurities. Cefdinir is a semi-synthetic, broad-spectrum antibiotic, used for soft tissue infections and respiratory tract infections. Synonyms: [2RS-[2α(Z),5α]]-2-Amino-α-(hydroxyimino)-N-[(1,2,5,7-tetrahydro-5-methyl-7-oxo-4H-furo[3,4-d][1,3]thiazin-2-yl)methyl]-4-thiazoleacetamide; N-[(5-Methyl-7-oxo-1,2,5,7-tetrahydro-4H-furo[3,4-d][1,3]thiazin)-2-ylmethyl]-2-(2-amino-4-thiazolyl)-2-[(Z)-hydroxyimino]acetamide; Cefdinir impurity H; Cefdinir decarboxy open ring lactone; Cefdinir Impurity 3 (Mixture of Diastereomers). Grades: 95%. CAS No. 178949-04-7. Molecular formula: C13H15N5O4S2. Mole weight: 369.42.
Ziprasidone Ring-opened Impurity (Impurity C)
One of the impurities of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. Synonyms: 2-[2-Amino-5-[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-4-chlorophenyl]acetic acid. CAS No. 1159977-64-6. Molecular formula: C21H23ClN4O2S. Mole weight: 430.96.
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