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Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolem ic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways. Source:Synthetic. Originally isolated from Streptomyces sp. Group: Biochemicals. Grades: Highly Purified. CAS No. 96829-58-2. Pack Sizes: 50mg, 250mg. Molecular Formula: C29H53NO5. US Biological Life Sciences.
Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase ( FASN ), is used orally for long-term research of obesity [1]. Anti-atherosclerotic effect [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tetrahydrolipstatin; Ro-18-0647. CAS No. 96829-58-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0218.
Orlistat
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardsbuilding blockschiral moleculespharmaceutical toxicology. Alternative Names: Ro 18-0647/002, Orlistat, L-Leucine, N-formyl-, 1-[(3-hexyl-4-oxo-2-oxetanyl)methyl]dodecyl ester, [2S-[2alpha(R*),3beta]]-, Tetrahydrolipstatin, Xenical,(-)-Tetrahydrolipstatin.
Orlistat-d3
Labeled Orlistat, an antiobesity agent. Orlistat is a pancreatic lipase inhibitor. Group: Biochemicals. Alternative Names: N-Formyl-L-leucine (1S) -1- [ [ (2S, 3S) -3-hexyl-4-oxo-2-oxetanyl] methyl] dodecyl Ester-d3; (-)-Tetrahydrolipstatin-d3; Ro 18-0647/002-d3; Tetrahydrolipstatin-d3; Xenical-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Orlistat degradation product sodium salt
A degradation product of the anti-obesity agent orlistat. Synonyms: Orlistat M3 Impurity; Sodium (2S,3S,5S)-2-hexyl-3,5-dihydroxyhexadecanoate. Grades: ≥95%. Molecular formula: C22H43O4·Na. Mole weight: 394.56.
Orlistat Dimer Impurity
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: O5-(N-Formyl-L-leucyl)-(2S,3S,5S)-2-hexyl-3,5-dihydroxyhexadecanoyl-L-leucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester. Grades: > 95%. CAS No. 881900-54-5. Molecular formula: C57H106N2O9. Mole weight: 963.49.
Orlistat Impurity
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: N-Formyl-L-leucine(1S)-1-[(2S,3S)-2-hydroxy-3-[(R)-1-phenylethylcarbomoyl)] nonyl]dodecyl Ester. Grades: > 95%. Molecular formula: C37H64N2O5. Mole weight: 616.93.
Orlistat Impurity 2
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: N-Formyl-L-leucine [S-(E)]-1-(2-Nonenyl)dodecyl Ester. Grades: > 95%. CAS No. 130676-63-0. Molecular formula: C28H53NO3. Mole weight: 451.74.
Orlistat Impurity 28
Orlistat Impurity 28. Uses: For analytical and research use. Group: Impurity standards. CAS No. 112836-64-3. Molecular formula: C22H40O3. Mole weight: 352.56. Catalog: APB112836643.
Orlistat Impurity 3
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)tridecan-2-yl 2-formamido-4-methylpentanoate. Grades: > 95%. Molecular formula: C28H51NO5. Mole weight: 481.72.
Orlistat Impurity 37
Orlistat Impurity 37. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104801-96-9. Molecular formula: C22H42O3. Mole weight: 354.58. Catalog: APB104801969.
Orlistat Impurity 39
Orlistat Impurity 39. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108102-74-5. Molecular formula: C28H53NO4. Mole weight: 467.74. Catalog: APB108102745.
Orlistat Impurity 45
Orlistat Impurity 45. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1072902-75-0. Molecular formula: C29H53NO5. Mole weight: 495.75. Catalog: APB1072902750.
Orlistat Impurity 47
Orlistat Impurity 47. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104872-28-8. Molecular formula: C29H53NO5. Mole weight: 495.75. Catalog: APB104872288.
Orlistat Impurity 8
Orlistat Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1243011-56-4. Molecular formula: C31H57NO5. Mole weight: 523.8. Catalog: APB1243011564.
Orlistat Impurity M1
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: (2S,3S,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic Acid; N-Formyl-L-leucine(1S)-1-[(2S,3S)-3-carboxy-2-hydroxynonyl]dodecyl Ester; 5-(Formamido-4-methylpentanoyloxy)-2-hexyl-3-hydroxyhexadecanoic Acid; Orlistat Impurity M1. Grades: > 95%. CAS No. 130676-66-3. Molecular formula: C29H55NO6. Mole weight: 513.76.
Orlistat Related Compound ((2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic acid)
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: (2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic Acid. Grades: > 95%. CAS No. 130793-28-1. Molecular formula: C29H55NO6. Mole weight: 513.76.
Orlistat Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Orlistat Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Orlistat Related Compound D
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: N-Formyl-L-leucine (3S,4R,6S)-3-Hexyltetrahydro-2-oxo-6-undecyl-2H-pyran-4-yl Ester; Orlistat USP Related Compound D. Grades: > 95%. CAS No. 130793-27-0. Molecular formula: C29H53NO5. Mole weight: 495.75.
Orlistat Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Orlistat Related Compound E
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Orlistat Related Compound [(S)-3-Hexyl-5,6-dihydro-6-undecyl-2H-pyran-2-one]
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: (S)-3-Hexyl-5,6-dihydro-6-undecyl-2H-pyran-2-one. Grades: > 95%. CAS No. 130676-64-1. Molecular formula: C22H40O2. Mole weight: 336.56.
Orlistat USP Related Compound B (Diisopropyl Hydrazine-1, 2-Dicarboxylate)
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: Bicarbamic Acid Diisopropyl Ester; 1,2-Hydrazinedicarboxylic Acid 1,2-Bis(1-methylethyl) Ester; 1,2-Hydrazinedicarboxylic Acid Bis(1-methylethyl) Ester; Bis(1-methylethyl) hydrazine-1,2-dicarboxylate. Grades: > 95%. CAS No. 19740-72-8. Molecular formula: C8H16N2O4. Mole weight: 204.23.
Orlistat USP Related Compound C (Triphenylphosphine Oxide)
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Uses: Used for processing (extraction, separation, and spectrophotometric determination) environmental samples of cadmium and mercury. Synonyms: Triphenylphosphine Oxide; Triphenylphosphine Monoxide; Orlistat Related Compound C; Orlistat USP Related Compound C. Grades: ≥ 99.5% (Assay). CAS No. 791-28-6. Molecular formula: C18H15OP. Mole weight: 278.29.
Orlistat USP Related Compound E
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: L-Isoleucine Orlistat; N-Formyl-L-isoleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester. Grades: > 95%. CAS No. 1072902-75-0. Molecular formula: C29H53NO5. Mole weight: 495.75.
A product from thermal and hydrolytic degradation. Group: Biochemicals. Alternative Names: [2R-[1(S*),2R*,3S*]]-N-Formyl-L-Leucine 1-[3-Carboxy-2-hydroxynonyl]dodecyl Ester; Orlistat Impurity. Grades: Highly Purified. CAS No. 130793-28-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
5-Methyl-L-Norleucine Orlistat Analogue
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: 5-Methyl-L-norleucine Orlistat Analogue;N-Formyl-5-methyl-L-norleucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester. Grades: > 95%. CAS No. 1356847-30-7. Molecular formula: C30H55NO5. Mole weight: 509.78.
L-Valine orlistat
L-Valine orlistat. Group: Biochemicals. Alternative Names: N-Formyl-L-valine (1S) -1- [ [ (2S, 3S) -3-hexyl-4-oxo-2-oxetanyl] methyl] dodecyl ester. Grades: Highly Purified. CAS No. 1243107-50-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C28H51NO5. US Biological Life Sciences.
Worldwide
N-Deformyl-N-benzyloxycarbonyl orlistat
N-Deformyl-N-benzyloxycarbonyl orlistat. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[(Phenylmethoxy)carbonyl]-L-Leucine (1S)-1-[[(2S,3S)-3-Hexyl-4 -oxo-2-oxetanyl]methyl]dodecyl Ester. Product Category: Heterocyclic Organic Compound. CAS No. 108051-94-1. Molecular formula: C36H59NO6. Mole weight: 601.86. Purity: 0.96. IUPACName: [(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoate. Canonical SMILES: CCCCCCCCCCCC(CC1C(C(=O)O1)CCCCCC)OC(=O)C(CC(C)C)NC(=O)OCC2=CC=CC=C2. Density: 1.018g/cm³. Product ID: ACM108051941. Alfa Chemistry ISO 9001:2015 Certified.
N-Deformyl-N-benzyloxycarbonyl Orlistat
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: N-Deformyl-N-benzyloxycarbonyl Orlistat; N-[(Phenylmethoxy)carbonyl]-L-Leucine (1S)-1-[[(2S,3S)-3-Hexyl-4 -oxo-2-oxetanyl]methyl]dodecyl Ester. Grades: > 95%. CAS No. 108051-94-1. Molecular formula: C36H59NO6. Mole weight: 601.87.
N-Deformyl-N-pivaloyl Orlistat
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: N-Deformyl-N-pivaloyl Orlistat; N-Desformyl-N-pivaloyl Orlistat. Grades: > 95%. CAS No. 1356017-35-0. Molecular formula: C33H61NO5. Mole weight: 551.86.
Octyl Orlistat
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: Octyl Orlistat; N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-Octyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester. Grades: > 95%. CAS No. 1243011-56-4. Molecular formula: 1243011-56-4. Mole weight: 523.8.
(R,R,R,R)-Orlistat
(R,R,R,R)-Orlistat. Group: Biochemicals. Alternative Names: N-Formyl-D-leucine (1R) -1- [ [ (2R, 3R) -3-Hexyl-4-oxo-2-oxetanyl] methyl] dodecyl Ester. Grades: Highly Purified. CAS No. 104872-27-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C29H53NO5. US Biological Life Sciences.
Worldwide
(R,R,S,S)-Orlistat
(R,R,S,S)-Orlistat. Group: Biochemicals. Alternative Names: N-Formyl-D-leucine (1R) -1- [ [ (2S, 3S) -3-Hexyl-4-oxo-2-oxetanyl] methyl] dodecyl Ester. Grades: Highly Purified. CAS No. 1225451-00-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C29H53NO5. US Biological Life Sciences.
Worldwide
(R,S,S,S)-Orlistat
An isomeric impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: N-Formyl-D-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester; [2S-[2α(R*),3β]]-N-Formyl-D-leucine 1-[(3-Hexyl-4-oxo-2-oxetanyl)methyl]dodecyl Ester. Grades: > 95%. CAS No. 104872-28-8. Molecular formula: C29H53NO5. Mole weight: 495.75.
An isomeric impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: N-Formyl-L-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester; [2R-[2α(R*),3β]]-N-Formyl-L-leucine 1-[(3-Ηexyl-4-oxo-2-oxetanyl)methyl]dodecyl Ester. Grades: > 95%. CAS No. 111466-61-6. Molecular formula: C29H53NO5. Mole weight: 495.75.
(S,R,R,R)-Orlistat
Orlistat isomer. Used in the asymmetric synthesis of. Group: Biochemicals. Alternative Names: N-Formyl-. Grades: Highly Purified. CAS No. 111466-61-6. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
(S,R,S,S) Orlistat
An isomeric impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: [2S-[2α(S*),3β]]-N-Formyl-L-leucine 1-[(3-Hexyl-4-oxo-2-oxetanyl)methyl]dodecyl Ester. Grades: > 95%. CAS No. 111466-63-8. Molecular formula: C29H53NO5. Mole weight: 495.75.
(S,R,S,S)-Orlistat
(S,R,S,S)-Orlistat. Group: Biochemicals. Alternative Names: [2S-[2a(S*),3b]]-N-Formyl-L-leucine 1-[ (3-Hexyl-4-oxo-2-oxetanyl) methyl]dodecyl Ester. Grades: Highly Purified. CAS No. 111466-63-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C29H53NO5. US Biological Life Sciences.
Worldwide
(S,S,R,R)-Orlistat
An isomeric impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase. Synonyms: [2R-[2α(S*),3β]]-N-Formyl-L-leucine 1-[(3-Hexyl-4-oxo-2-oxetanyl)methyl]dodecyl Ester. Grades: > 95%. CAS No. 111466-62-7. Molecular formula: C29H53NO5. Mole weight: 495.75.
(S,S,R,R)-Orlistat
(S,S,R,R)-Orlistat. Group: Biochemicals. Alternative Names: [2R-[2a(S*),3b]]-N-Formyl-L-leucine 1-[ (3-Hexyl-4-oxo-2-oxetanyl) methyl]dodecyl Ester. Grades: Highly Purified. CAS No. 111466-62-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C29H53NO5. US Biological Life Sciences.
Orlistat impurity M3. Group: Biochemicals. Alternative Names: [2S-(2R*,3R*,5R*)]-. Grades: Highly Purified. CAS No. 130793-30-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(2S,3S,5S)-2-Hexyl-3,5-dihydroxyhexadecanoic Acid Sodium Salt
(2S,3S,5S)-2-Hexyl-3,5-dihydroxyhexadecanoic Acid Sodium Salt is the salt analogue of (2S,3S,5S)-2-Hexyl-3,5-dihydroxyhexadecanoic Acid (H295850), an Orlistat (O686500) impurity M3. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C22H43NaO4. US Biological Life Sciences.
Worldwide
(2S,3S,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic Acid-d3 (Mixture of Diastereomers)
A labeled metabolite of Orlistat. Group: Biochemicals. Alternative Names: N-Formyl-L-leucine(1S)-1-[(2S,3S)-3-carboxy-2-hydroxynonyl]dodecyl Ester-d3; 5-(Formamido-4-methylpentanoyloxy)-2-hexyl-3-hydroxyhexadecanoic Acid-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
(3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]-2-oxetanone is an analog of Tetrahydrolipstatin, an inhibitor of the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG), also an intermediate in the preparation of Orlistat. Group: Biochemicals. Alternative Names: [3S-[3α,4 β(R*)]]-3-Hexyl-4-(2-hydroxytridecyl)-2-oxetanone; (3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. Grades: Highly Purified. CAS No. 68711-40-0. Pack Sizes: 1mg. US Biological Life Sciences.
An analog of Tetrahydrolipstatin, an inhibitor of the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG), also an intermediate in the preparation of Orlistat. Synonyms: (3S,4S)-3-Hexyl-4-((S)-2-hydroxytridecyl)oxetan-2-one. CAS No. 68711-40-0. Molecular formula: C22H42O3. Mole weight: 354.57.
Cetilistat
Cetilistat, also known as ATL-962, is a drug designed to treat obesity. It acts in the same way as the older drug orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Uses: Anti-obesity agents. Synonyms: ATL-962; ATL962; ATL 962; Cetilistat. Grades: 98%. CAS No. 282526-98-1. Molecular formula: C25H39NO3. Mole weight: 401.59.
Labeled N-Formyl-L-leucine (3S,4S,6S)-3-Hexyltetrahydro-2-oxo-6-undecyl-2H-pyran-4-yl ester is an impurity of Orlistat. Group: Biochemicals. Alternative Names: [3S-(3α,4α,6 β)]-N-Formyl-L-leucine 3-Hexyltetrahydro-2-oxo-6-undecyl-2H-pyran-4-yl-d3 Ester; Ro 40-4441-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
(S,R,R,R)-Orlistat (O686495) impurity. Group: Biochemicals. Alternative Names: cis-3-Hexyl-4-[2-hydroxytridecyl]-2-oxetanone. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
(S)-3-Hexyl-5,6-dihydro-6-undecyl-2H-pyran-2-one
A degradation product of Tetrahydrolipstatin (Orlistat). Orlistat impurity. Group: Biochemicals. Alternative Names: Orlistat Impurity. Grades: Highly Purified. CAS No. 130676-64-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
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